ru-28362 has been researched along with mifepristone in 26 studies
| Studies (ru-28362) | Trials (ru-28362) | Recent Studies (post-2010) (ru-28362) | Studies (mifepristone) | Trials (mifepristone) | Recent Studies (post-2010) (mifepristone) |
|---|---|---|---|---|---|
| 175 | 0 | 3 | 6,536 | 595 | 1,758 |
| Protein | Taxonomy | ru-28362 (IC50) | mifepristone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Canis lupus familiaris (dog) | 0.0264 | |
| Bile salt export pump | Homo sapiens (human) | 2.02 | |
| Estrogen receptor | Homo sapiens (human) | 4.311 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.0249 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.0003 | |
| Progesterone receptor | Homo sapiens (human) | 0.1347 | |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | 0.774 | |
| Glucocorticoid receptor | Mus musculus (house mouse) | 0.0022 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 2.0938 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 9.5 | |
| Coagulation factor VII | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Homo sapiens (human) | 0.2988 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 1.5 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4.9 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 0.0016 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 0.555 | |
| Tissue factor | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.0083 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0014 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.0022 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0078 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Mu-type opioid receptor | Homo sapiens (human) | 2.457 | |
| Estrogen receptor beta | Homo sapiens (human) | 1.528 | |
| Glucocorticoid receptor | Sus scrofa (pig) | 0.0153 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 20 (76.92) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farnworth, P; Michel, U | 1 |
| De Moraes, S; Nourani, R; Rahnemaye, F; Spadari, RC | 1 |
| Funder, JW; Myles, K; Pearce, PT; Roy, LP | 1 |
| de Jong, W; de Kloet, ER; van den Berg, DT; van Dijken, HH | 1 |
| Agarwal, MK; Hainque, B; Moustaid, N; Quignard-Boulange, A | 1 |
| King, I; Sartorelli, AC; Violette, SM | 1 |
| Dixon, JE; Glembotski, CC; Shields, PP | 1 |
| Asher, C; Civian, MM; Garty, H; Peterson-Yantorno, K | 1 |
| Funder, JW; Provencher, PH; Saltis, J | 1 |
| Briski, KP; Sylvester, PW | 1 |
| Dean, RG; Edwards, GL; Martin, RJ; White, BD | 1 |
| de Kloet, ER; Joëls, M | 1 |
| Dayanithi, G; Gratzl, M; Link, H | 1 |
| Hunt, A; Kelly, FJ; Langley, SC; Postle, AD; Rickett, GW; York, DA | 1 |
| Bahn, RS; Heufelder, AE; Wenzel, BE | 1 |
| Burollaud, T; Danzé, PM; Dautrevaux, M; Formstecher, P; Tbarka, N | 1 |
| Husted, RF; Schmidt, TJ; Stokes, JB | 1 |
| McGaugh, JL; Roozendaal, B | 2 |
| Fujita, H; Maeda, N; Matsuda, S; Sakanaka, M; Tanaka, J; Toku, K | 1 |
| Asselin, C; Boudreau, F; Morin, C; Provencher, PH | 1 |
| McGaugh, JL; Roozendaal, B; Williams, CL | 1 |
| Hattori, TA; Kawato, S; Kimoto, T; Takahashi, T; Tanabe, N; Yasumatsu, N | 1 |
| Allaman, I; Magistretti, PJ; Pellerin, L | 1 |
| Ghitza, UE; Li, YQ; Lu, L; Wang, XY; Zhao, M | 1 |
| Dallman, MF; Ginsberg, AB; Horneman, HF; Pecoraro, NC; Warne, JP | 1 |
26 other study(ies) available for ru-28362 and mifepristone
| Article | Year |
|---|---|
Follistatin steady state messenger ribonucleic acid levels in confluent cultures of a rat renal mesangial cell line are regulated by multiple factors.
Topics: Activins; Amino Acid Isomerases; Androstanols; Angiotensin II; Animals; Base Sequence; Carrier Proteins; Cell Line; Cells, Cultured; Cyclosporins; Dihydrotestosterone; Dinoprostone; Epidermal Growth Factor; Estradiol; Fibroblast Growth Factor 2; Follistatin; Gene Expression; Glomerular Mesangium; Glycoproteins; Inhibins; Mifepristone; Molecular Sequence Data; Oligodeoxyribonucleotides; Peptidylprolyl Isomerase; Progesterone; Rats; RNA; RNA Probes; RNA, Messenger; Somatostatin; Tretinoin | 1992 |
Footshock stress-induced supersensitivity to isoprenaline in the isolated pacemaker of the rat: effects of the compounds RU-38486 and RU-28362.
Topics: Androstanols; Animals; Biological Clocks; Cytosol; Dose-Response Relationship, Drug; Electroshock; Heart Rate; Isoproterenol; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Steroid; Stress, Psychological | 1992 |
Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aldosterone; Androstanols; Animals; Bicarbonates; Carbenoxolone; Child; Electrolytes; Female; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Male; Mifepristone; Mineralocorticoids; Natriuresis; Pseudohypoaldosteronism; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone | 1990 |
Differential central effects of mineralocorticoid and glucocorticoid agonists and antagonists on blood pressure.
Topics: Adrenalectomy; Aldosterone; Androstanols; Animals; Blood Pressure; Brain; Corticosterone; Glucocorticoids; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats; Rats, Inbred Strains; Spironolactone | 1990 |
Analysis of the glucocorticoid receptor during differentiation of 3T3-F442A preadipocyte cell line in culture.
Topics: Adipose Tissue; Androstanols; Binding, Competitive; Cell Differentiation; Cell Line; Dexamethasone; Kinetics; Mifepristone; Receptors, Glucocorticoid | 1990 |
Induction of the terminal differentiation of a human squamous cell carcinoma by steroids with glucocorticoid activity.
Topics: 17-alpha-Hydroxyprogesterone; Androstanols; Carcinoma, Squamous Cell; Cell Differentiation; Desoxycorticosterone; Dose-Response Relationship, Drug; Glucocorticoids; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Mifepristone; Mineralocorticoids; Neovascularization, Pathologic; Progesterone; Tretinoin; Tumor Cells, Cultured | 1989 |
The secretion of atrial natriuretic factor-(99-126) by cultured cardiac myocytes is regulated by glucocorticoids.
Topics: Amino Acids; Androstanols; Animals; Atrial Natriuretic Factor; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Cytoplasmic Granules; Dexamethasone; Diuretics; Estrenes; Glucocorticoids; Heart Atria; Immunohistochemistry; Immunosorbent Techniques; Mifepristone; Myocardium; Peptide Fragments; Protein Processing, Post-Translational; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
Effects of corticoid agonists and antagonists on apical Na+ permeability of toad urinary bladder.
Topics: Adrenal Cortex Hormones; Aldosterone; Androstanols; Animals; Bufo marinus; Cell Membrane Permeability; Injections; Mifepristone; Oocytes; Receptors, Mineralocorticoid; RNA; Sodium; Sodium Channels; Urinary Bladder; Xenopus | 1994 |
Glucocorticoids but not mineralocorticoids modulate endothelin-1 and angiotensin II binding in SHR vascular smooth muscle cells.
Topics: Aldosterone; Androstanols; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Endothelin Receptor Antagonists; Endothelins; Glucocorticoids; Hypertension; Imidazoles; Losartan; Male; Mifepristone; Muscle, Smooth, Vascular; Peptides, Cyclic; Rats; Rats, Inbred SHR; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Tetrazoles; Viper Venoms | 1995 |
Antagonism of type II, but not type I glucocorticoid receptors results in elevated basal luteinizing hormone release in male rats.
Topics: Androstanols; Animals; Canrenone; Glucocorticoids; Luteinizing Hormone; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 1994 |
Type II corticosteroid receptor stimulation increases NPY gene expression in basomedial hypothalamus of rats.
Topics: Adrenalectomy; Aldosterone; Androstanols; Animals; Blood Glucose; Drug Interactions; Gene Expression Regulation; Hypothalamus, Middle; Infusions, Parenteral; Insulin; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, Steroid; RNA, Messenger; Spironolactone | 1994 |
Corticosteroid actions on amino acid-mediated transmission in rat CA1 hippocampal cells.
Topics: Action Potentials; Adrenalectomy; Aldosterone; Androstanols; Animals; Corticosterone; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mifepristone; Neurons; Pyramidal Tracts; Rats; Rats, Wistar; Synapses; Time Factors | 1993 |
Glucocorticoids rapidly inhibit oxytocin-stimulated adrenocorticotropin release from rat anterior pituitary cells, without modifying intracellular calcium transients.
Topics: Adrenocorticotropic Hormone; Androstanols; Animals; Calcium; Cells, Cultured; Corticosterone; Female; In Vitro Techniques; Kinetics; Mifepristone; Oxytocin; Pituitary Gland, Anterior; Rats; Rats, Wistar; Time Factors | 1993 |
Effects of the glucocorticoid agonist, RU28362, and the antagonist RU486 on lung phosphatidylcholine and antioxidant enzyme development in the genetically obese Zucker rat.
Topics: Androstanols; Animals; Body Weight; Eating; Glucocorticoids; Lung; Male; Mifepristone; Organ Size; Phospholipids; Rats; Rats, Zucker; Receptors, Glucocorticoid | 1993 |
Glucocorticoids modulate the synthesis and expression of a 72 kDa heat shock protein in cultured Graves' retroocular fibroblasts.
Topics: Androstanols; Blotting, Western; Cells, Cultured; Connective Tissue; Dexamethasone; Dose-Response Relationship, Drug; Eye; Fibroblasts; Fluorescent Antibody Technique; Graves Disease; Heat-Shock Proteins; Hot Temperature; Humans; Mifepristone; Receptors, Glucocorticoid | 1993 |
Binding of RU486 and deacylcortivazol to the glucocorticoid receptor is insensitive to sulfhydryl-modifying agents.
Topics: Alkylation; Androstanols; Animals; Binding, Competitive; Ethylmaleimide; Liver; Male; Maleimides; Mifepristone; Pregnatrienes; Rats; Rats, Wistar; Receptors, Glucocorticoid; Structure-Activity Relationship; Sulfhydryl Reagents; Triamcinolone Acetonide | 1993 |
Steroid hormone stimulation of Na+ transport in A6 cells is mediated via glucocorticoid receptors.
Topics: Androstanols; Animals; Biological Transport, Active; Cell Line; DNA-Binding Proteins; Glucocorticoids; Kidney; Kinetics; Mifepristone; Mineralocorticoids; Nephrons; Receptors, Glucocorticoid; Sodium; Structure-Activity Relationship; Triamcinolone Acetonide; Xenopus laevis | 1993 |
Basolateral amygdala lesions block the memory-enhancing effect of glucocorticoid administration in the dorsal hippocampus of rats.
Topics: Amygdala; Androstanols; Animals; Avoidance Learning; Electroshock; Glucocorticoids; Hippocampus; Hormone Antagonists; Injections, Intraventricular; Male; Maze Learning; Memory; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 1997 |
Glucocorticoid receptor agonist and antagonist administration into the basolateral but not central amygdala modulates memory storage.
Topics: Amygdala; Androstanols; Animals; Male; Maze Learning; Memory; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 1997 |
Glucocorticoid- and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Androstanols; Animals; Animals, Newborn; Cells, Cultured; Cholesterol; Corticosterone; Culture Media; Culture Media, Serum-Free; Dehydroepiandrosterone; Dexamethasone; Estradiol; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrocortisone; Microglia; Mifepristone; Pregnenolone; Proliferating Cell Nuclear Antigen; Prosencephalon; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Testosterone | 1997 |
Transcriptional regulation of pre-pro-endothelin-1 gene by glucocorticoids in vascular smooth muscle cells.
Topics: Androstanols; Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelin-1; Endothelins; Gene Expression Regulation; Glucocorticoids; Hormone Antagonists; Mifepristone; Muscle, Smooth, Vascular; Protein Precursors; Rats; RNA, Messenger; Transcription, Genetic | 1998 |
Glucocorticoid receptor activation in the rat nucleus of the solitary tract facilitates memory consolidation: involvement of the basolateral amygdala.
Topics: Amygdala; Androstanols; Animals; Avoidance Learning; Cerebellum; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Hormone Antagonists; Injections, Intraventricular; Male; Memory; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Solitary Nucleus | 1999 |
Corticosterone acutely prolonged N-methyl-d-aspartate receptor-mediated Ca2+ elevation in cultured rat hippocampal neurons.
Topics: Androstanols; Animals; Calcium; Calcium Signaling; Cells, Cultured; Corticosterone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Hippocampus; Hormone Antagonists; Membrane Potentials; Mifepristone; Mitochondria; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate | 2002 |
Glucocorticoids modulate neurotransmitter-induced glycogen metabolism in cultured cortical astrocytes.
Topics: Androstanols; Animals; Animals, Newborn; Astrocytes; Blotting, Northern; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Deoxyglucose; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; Glucocorticoids; Glycogen; Hormone Antagonists; Intracellular Signaling Peptides and Proteins; Lactase; Mice; Mifepristone; Neurotransmitter Agents; Norepinephrine; RNA, Messenger; Tritium | 2004 |
Stress impairs reconsolidation of drug memory via glucocorticoid receptors in the basolateral amygdala.
Topics: Amygdala; Analgesics, Opioid; Androstanols; Animals; Association Learning; Behavior, Animal; Conditioning, Operant; Corticosterone; Drug Administration Routes; Enzyme Inhibitors; Hormone Antagonists; Male; Memory Disorders; Metyrapone; Mifepristone; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward; Stress, Psychological | 2008 |
Rapid alteration of stress-induced hypothalamic-pituitary-adrenal hormone secretion in the rat: a comparison of glucocorticoids and cannabinoids.
Topics: Adrenocorticotropic Hormone; Androstanols; Animals; Cannabinoids; Dose-Response Relationship, Drug; Feedback, Physiological; Glucocorticoids; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Paraventricular Hypothalamic Nucleus; Piperidines; Pituitary-Adrenal System; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Glutamate; Restraint, Physical; Stress, Physiological | 2010 |