rtki cpd has been researched along with tyrosine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (11.76) | 18.2507 |
| 2000's | 29 (85.29) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DeWild, LJ; Klein, JM; McCarthy, TA | 1 |
| Soltoff, SP | 1 |
| Ben-Bassat, H; Klein, BY; Rojansky, N; Stekelenburg, J | 1 |
| Akhand, AA; Kato, M; Kurokawa, K; Liu, W; Miyata, T; Nakashima, I; Uchida, K; Yokoyama, I | 1 |
| Ogata, T | 1 |
| Eguchi, S; Hirata, Y; Iwasaki, H; Marumo, F; Ueno, H | 1 |
| Bagnato, A; Catt, KJ; Tecce, R; Vacca, F | 1 |
| Adachi, H; Fujioka, T; Kim, JH; Saito, K; Tsujimoto, M; Ui, M; Yokoyama, S | 1 |
| El-Obeid, A; Hesselager, G; Nistér, M; Westermark, B | 1 |
| Bode, AM; Chen, N; Dong, Z; Ma, WY; Zhang, Y | 1 |
| Chen, X; Resh, MD | 1 |
| Huang, XL; Lawrence, M; Madara, P; Nanavaty, UB; Pawliczak, R; Shelhamer, JH | 1 |
| Hunger-Glaser, I; Rozengurt, E; Salazar, EP | 1 |
| Marcoux, N; Vuori, K | 1 |
| Barrett, KE; Bertelsen, LS; Keely, SJ | 1 |
| Adachi, T; Chihara, J; Cui, CH; Kanda, A; Kayaba, H; Ohta, K | 1 |
| Brown, EM; Chattopadhyay, N; MacLeod, RJ; Yano, S | 1 |
| Barki-Harrington, L; El-Shewy, HM; Kelly, FL; Luttrell, LM | 1 |
| Abulrob, A; Andrade, MF; Giuseppin, S; McDermid, A; Moreno, M; Stanimirovic, D | 1 |
| Basuroy, S; Rao, RK; Seth, A; Sheth, P | 1 |
| Delamere, NA; Tamiya, S | 1 |
| Fujioka, A; Itoh, RE; Kurokawa, K; Matsuda, M; Mayer, BJ; Sharma, A | 1 |
| Mariappa, D; Seshagiri, PB; Shivaji, S; Siva, AB | 1 |
| Cai, K; Enomoto, A; Hosoi, Y; Li, Z; Matsumoto, Y; Miyagawa, K; Morita, A; Nakagawa, K; Tanno, Y | 1 |
| Hur, GY; In, KH; Jung, HC; Jung, KH; Kang, EJ; Kang, KH; Kim, JH; Lee, SY; Shim, JJ; Shin, C; Yoo, SH | 1 |
| Bergmann, S; Henklein, P; Hollenberg, MD; Junker, K; Kaufmann, R; Settmacher, U | 1 |
| Arany, I; Megyesi, JK; Nelkin, BD; Safirstein, RL | 1 |
| Bette, M; Folz, BJ; Mandic, R; Neubauer, A; Rodgarkia-Dara, CJ; Weihe, E; Werner, JA; Zhu, L | 1 |
| Azar, ZM; Mehdi, MZ; Srivastava, AK | 1 |
| Chao, HH; Chen, YL; Cheng, TH; Chiu, WT; Hong, HJ; Lin, JW; Liu, JC; Shyu, KG; Wu, CH | 1 |
| Bhattacharya, S; Johnson, LR; Ray, RM | 1 |
| Arao, T; Fujita, Y; Ito, F; Kaneda, H; Kudo, K; Maegawa, M; Matsumoto, K; Nishio, K; Tanaka, K; Yokote, H | 1 |
| Amosova, AP; Chernorudskiy, AL; Kondratov, KA; Kornilova, ES | 1 |
| Chen, HC; Dou, BB; Fu, JY; Liu, WT; Miao, L; Tan, C; Wang, XR; Yang, B; Yang, RC; Yang, XP; Zhang, T | 1 |
34 other study(ies) available for rtki cpd and tyrosine
| Article | Year |
|---|---|
Effect of tyrosine kinase inhibition on surfactant protein A gene expression during human lung development.
Topics: Embryonic and Fetal Development; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Genistein; Homeostasis; Humans; Lung; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Quinazolines; RNA, Messenger; Tyrosine; Tyrphostins | 1998 |
Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen-activated protein kinase by the G-protein-coupled P2Y2 receptor. Phorbol ester or [Ca2+]i elevation can substitute for receptor activation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Focal Adhesion Kinase 2; GTP-Binding Proteins; Ionomycin; Models, Biological; Nitriles; PC12 Cells; Phorbol Esters; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Quinazolines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine; Tyrphostins; Ubiquitin-Protein Ligases; Uridine Triphosphate | 1998 |
Opposing effects of cyclosporin A and tyrphostin AG-1478 indicate a role for Src protein in the cellular control of mineralization.
Topics: Animals; Calcification, Physiologic; Cell Differentiation; Cells, Cultured; Cyclosporine; Dexamethasone; Enzyme Inhibitors; Female; Phosphorylation; Proteins; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Rats; Rats, Inbred Strains; Stromal Cells; Tyrosine; Tyrphostins | 1998 |
4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition.
Topics: Aldehydes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cross-Linking Reagents; Enzyme Activation; ErbB Receptors; Genistein; Humans; Lipid Peroxidation; Oxidative Stress; Phosphoproteins; Phosphorylation; Quinazolines; Signal Transduction; Tyrosine; Tyrphostins | 1999 |
Fluid flow-induced tyrosine phosphorylation and participation of growth factor signaling pathway in osteoblast-like cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Cell Line; Culture Media; DNA-Binding Proteins; Early Growth Response Protein 1; Epidermal Growth Factor; Gene Expression Regulation; Immediate-Early Proteins; Mice; Mitogen-Activated Protein Kinase 1; Osteoblasts; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Quinazolines; RNA, Messenger; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Stress, Mechanical; Transcription Factors; Tyrosine; Tyrphostins | 2000 |
Mechanical stretch stimulates growth of vascular smooth muscle cells via epidermal growth factor receptor.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium; Cell Division; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; GRB2 Adaptor Protein; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Physical Stimulation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; Rats; Rats, Sprague-Dawley; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine; Tyrphostins | 2000 |
Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Cell Division; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Ovarian Neoplasms; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proteins; Quinazolines; Receptor, Endothelin A; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2000 |
Further evidence for the involvement of insulin receptor substrates in epidermal growth factor-induced activation of phosphatidylinositol 3-kinase.
Topics: Androstadienes; Animals; Cell-Free System; CHO Cells; Cricetinae; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunoblotting; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Structure, Tertiary; Quinazolines; Receptor, Insulin; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Wortmannin | 2001 |
TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor.
Topics: Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cell Division; DNA, Complementary; Enzyme Inhibitors; ErbB Receptors; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; RNA; RNA, Messenger; Tetracycline; Time Factors; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2002 |
Induction of EGFR-dependent and EGFR-independent signaling pathways by ultraviolet A irradiation.
Topics: Animals; Blotting, Western; Cell Line; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Quinazolines; Ribosomal Protein S6 Kinases; Signal Transduction; Transfection; Tyrosine; Tyrphostins; Ultraviolet Rays | 2001 |
Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; beta-Cyclodextrins; Blotting, Western; Cell Membrane; Cholesterol; COS Cells; Cross-Linking Reagents; Culture Media, Serum-Free; Cyclodextrins; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Immunoblotting; Isoenzymes; Ligands; Mass Spectrometry; Membrane Microdomains; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Proteins; Quinazolines; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Type C Phospholipases; Tyrosine; Tyrphostins | 2002 |
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
Topics: Antineoplastic Agents; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Ionophores; Lung; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; Quinazolines; ras Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins | 2002 |
Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Bradykinin; Cytoskeletal Proteins; Endothelins; Enzyme Inhibitors; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Lysophospholipids; Mice; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Stress Fibers; Tyrosine; Tyrphostins; Vasoconstrictor Agents; Vasopressins | 2003 |
EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2.
Topics: Actins; Animals; Cell Adhesion; Cells, Cultured; COS Cells; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Guanosine Triphosphate; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Oncogene Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-vav; Quinazolines; rac GTP-Binding Proteins; Tyrosine; Tyrphostins | 2003 |
Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.
Topics: Androstadienes; Blotting, Western; Cell Line; Chlorides; Chlorine; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; GTP-Binding Protein alpha Subunits, Gs; Humans; Ions; Isoquinolines; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Quinazolines; Sulfonamides; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Vasoactive Intestinal Peptide; Wortmannin | 2004 |
Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells.
Topics: Bronchi; Cell Line; Chemokine CCL11; Chemokines, CC; Epithelial Cells; ErbB Receptors; Humans; Interleukin-8; Phosphorylation; Quinazolines; Receptor Cross-Talk; Receptors, CCR3; Receptors, Chemokine; Signal Transduction; Tyrosine; Tyrphostins | 2004 |
Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism.
Topics: Cell Line; Enzyme Inhibitors; ErbB Receptors; Humans; Phosphorylation; Quinazolines; Receptors, Calcium-Sensing; Signal Transduction; Transcriptional Activation; Tyrosine; Tyrphostins | 2004 |
Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I.
Topics: Animals; Cell Line; Chlorocebus aethiops; Endocytosis; ErbB Receptors; Humans; Insulin-Like Growth Factor I; Metalloendopeptidases; Mice; Mitogen-Activated Protein Kinase 3; Paracrine Communication; Phenylalanine; Phosphorylation; Quinazolines; Rats; Receptors, Somatomedin; Tetradecanoylphorbol Acetate; Thiophenes; Tyrosine; Tyrphostins | 2004 |
Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae.
Topics: Caveolin 1; Caveolins; Cell Division; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Phosphorylation; Quinazolines; Tyrosine; Tyrphostins | 2004 |
L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer.
Topics: Acetaldehyde; Actins; Adherens Junctions; Caco-2 Cells; Cell Membrane Permeability; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Egtazic Acid; Endotoxins; ErbB Receptors; Glutamine; Humans; Lipopolysaccharides; Mannitol; Membrane Proteins; Occludin; Phosphorylation; Quinazolines; Tight Junctions; Tyrosine; Tyrphostins | 2004 |
Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.
Topics: Animals; Blotting, Western; Cell Proliferation; Enzyme Inhibitors; Epithelium; Lens, Crystalline; Organ Culture Techniques; Phosphorylation; Phosphotyrosine; Proliferating Cell Nuclear Antigen; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; src-Family Kinases; Swine; Tyrosine; Tyrphostins | 2005 |
A FRET-based probe for epidermal growth factor receptor bound non-covalently to a pair of synthetic amphipathic helixes.
Topics: Animals; Antibodies, Monoclonal; Chlorocebus aethiops; COS Cells; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Fluorescence Recovery After Photobleaching; Fluorescence Resonance Energy Transfer; HeLa Cells; Humans; Immunoblotting; Kinetics; Microscopy, Video; Molecular Probes; Phosphorylation; Precipitin Tests; Protein Binding; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Quinazolines; Tyrosine; Tyrphostins | 2005 |
Tyrphostin-A47 inhibitable tyrosine phosphorylation of flagellar proteins is associated with distinct alteration of motility pattern in hamster spermatozoa.
Topics: Animals; Cells, Cultured; Computer Simulation; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flagella; Male; Phosphorylation; Quinazolines; Sperm Motility; Spermatozoa; Time Factors; Tyrosine; Tyrphostins | 2006 |
Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation.
Topics: Androstadienes; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Guanosine Triphosphate; Humans; Immunoblotting; Immunoprecipitation; Infrared Rays; Intracellular Signaling Peptides and Proteins; Kinetics; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; Radiation, Ionizing; Signal Transduction; src-Family Kinases; Temperature; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Wortmannin; X-Rays | 2006 |
Peroxisome proliferator-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells.
Topics: Carcinoma, Mucoepidermoid; Cell Line, Tumor; Down-Regulation; Enzyme Inhibitors; ErbB Receptors; Humans; Hypoglycemic Agents; Lung Neoplasms; Mucin 5AC; Mucins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Respiratory Mucosa; Rosiglitazone; Smoking; Thiazolidinediones; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins | 2006 |
PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migration.
Topics: Cell Line, Tumor; Cell Movement; Dipeptides; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Kidney Neoplasms; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Oligopeptides; Phosphorylation; Pyrroles; Quinazolines; Receptor, PAR-1; Thrombin; Tyrosine; Tyrphostins | 2006 |
STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells.
Topics: Animals; Cell Line; Cell Survival; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Hydrogen Peroxide; Janus Kinase 2; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Quinazolines; Signal Transduction; STAT3 Transcription Factor; Tyrosine; Tyrphostins | 2006 |
Treatment of HNSCC cell lines with the EGFR-specific inhibitor cetuximab (Erbitux) results in paradox phosphorylation of tyrosine 1173 in the receptor.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Survival; Cetuximab; Cisplatin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Head and Neck Neoplasms; Humans; Phosphorylation; Quinazolines; Tyrosine; Tyrphostins | 2006 |
Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells.
Topics: Animals; Cell Line; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Focal Adhesion Kinase 2; Hydrogen Peroxide; Immunoblotting; Insulin-Like Growth Factor I; Models, Biological; Muscle, Smooth, Vascular; Oxidants; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Quinazolines; Receptor, IGF Type 1; src-Family Kinases; Tyrosine; Tyrphostins | 2006 |
Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Blotting, Northern; Blotting, Western; Butadienes; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Endothelin-1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Leptin; Male; Metalloendopeptidases; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Signal Transduction; Transcriptional Activation; Tyrosine; Tyrphostins | 2007 |
EGFR plays a pivotal role in the regulation of polyamine-dependent apoptosis in intestinal epithelial cells.
Topics: Animals; Apoptosis; Cell Survival; Cycloheximide; Eflornithine; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibronectins; Integrin beta3; Intestinal Mucosa; MAP Kinase Kinase Kinases; Mice; Mutation; Oligopeptides; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Protein Kinase Inhibitors; Putrescine; Pyrimidines; Quinazolines; Rats; Signal Transduction; src-Family Kinases; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins | 2007 |
Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor.
Topics: Blotting, Western; Cell Line; Enzyme Inhibitors; ErbB Receptors; Humans; Immunoprecipitation; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; Transfection; Tyrosine; Tyrphostins | 2009 |
Termination of tyrphostin AG1478 application results in different recovery of EGF receptor tyrosine residues 1045 and 1173 phosphorylation in A431 cells.
Topics: Cell Line, Tumor; Endocytosis; ErbB Receptors; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proto-Oncogene Proteins c-cbl; Quinazolines; Tyrosine; Tyrphostins; Ubiquitination | 2009 |
EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis.
Topics: Amphiregulin; Animals; Brain; Cytokines; Endothelial Cells; Enzyme Inhibitors; ErbB Receptors; Female; Humans; Meningitis; Mice; Phosphorylation; Quinazolines; Receptor, ErbB-3; Signal Transduction; Streptococcal Infections; Streptococcus suis; Swine; Transcriptional Activation; Tyrosine; Tyrphostins | 2016 |