Page last updated: 2024-09-03

rti 121 and bupropion

rti 121 has been researched along with bupropion in 3 studies

*Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE. [MeSH]

*Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE. [MeSH]

Compound Research Comparison

Studies
(rti 121)
Trials
(rti 121)
Recent Studies (post-2010)
(rti 121)
Studies
(bupropion)
Trials
(bupropion)
Recent Studies (post-2010) (bupropion)
641113,3927551,329

Protein Interaction Comparison

ProteinTaxonomyrti 121 (IC50)bupropion (IC50)
Acetylcholine receptor subunit alphaHomo sapiens (human)5.2693
Acetylcholine receptor subunit gammaHomo sapiens (human)5.2693
Integrin alpha-5Homo sapiens (human)1.8
Acetylcholine receptor subunit betaHomo sapiens (human)5.2693
Neuronal acetylcholine receptor subunit beta-2Homo sapiens (human)0.9373
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.2003
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)1.2028
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)1.367
Cytochrome P450 2C19Homo sapiens (human)1.9983
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)7.9
Neuronal acetylcholine receptor subunit alpha-4Homo sapiens (human)0.0135
Sodium-dependent dopamine transporter Homo sapiens (human)1.0848
Acetylcholine receptor subunit deltaHomo sapiens (human)5.2693

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boja, JW; Carroll, FI; Kuhar, MJ; Lever, SZ; Scheffel, U; Stathis, M1
Cadet, JL; Ladenheim, B; Tella, SR1
Bevan, M; Davidson, C; Meintel, M; Opacka-Juffry, J; Patel, N; Pinnell, T1

Other Studies

3 other study(ies) available for rti 121 and bupropion

ArticleYear
Rate of binding of various inhibitors at the dopamine transporter in vivo.
    Psychopharmacology, 1995, Volume: 119, Issue:4

    Topics: Animals; Binding, Competitive; Bupropion; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Time Factors

1995
Differential regulation of dopamine transporter after chronic self-administration of bupropion and nomifensine.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Animals; Bupropion; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration

1997
Stimulant mechanisms of cathinones - effects of mephedrone and other cathinones on basal and electrically evoked dopamine efflux in rat accumbens brain slices.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Oct-03, Volume: 54

    Topics: Amphetamine; Amphetamines; Animals; Bupropion; Central Nervous System Stimulants; Cocaine; Diethylpropion; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Electric Stimulation; Iodine Radioisotopes; Male; Methamphetamine; Microelectrodes; Nucleus Accumbens; Propiophenones; Radioligand Assay; Rats, Wistar; Tissue Culture Techniques

2014