Compounds > rti 121
Page last updated: 2024-09-03

rti 121 and benztropine

rti 121 has been researched along with benztropine in 2 studies

Compound Research Comparison

Studies
(rti 121)		Trials
(rti 121)		Recent Studies (post-2010)
(rti 121)		Studies
(benztropine)		Trials
(benztropine)		Recent Studies (post-2010) (benztropine)
641117359385

Protein Interaction Comparison

ProteinTaxonomyrti 121 (IC50)benztropine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.061
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.391
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0366
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0037
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.002
Alpha-2A adrenergic receptorHomo sapiens (human)0.544
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0005
Alpha-2B adrenergic receptorHomo sapiens (human)0.065
Alpha-2C adrenergic receptorHomo sapiens (human)0.395
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0106
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.391
Histamine H2 receptorHomo sapiens (human)1.206
Alpha-1D adrenergic receptorHomo sapiens (human)0.052
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.024
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.061
Histamine H1 receptorHomo sapiens (human)0.0032
D(3) dopamine receptorHomo sapiens (human)0.654
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.2
5-hydroxytryptamine receptor 6Homo sapiens (human)2.788
Sodium-dependent dopamine transporter Homo sapiens (human)0.2948
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.139

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Desai, RI; Katz, JL; Koffarnus, M; Kopajtic, TA; Newman, AH1
Desai, RI; French, D; Katz, JL; Kopajtic, TA; Newman, AH1

Other Studies

2 other study(ies) available for rti 121 and benztropine

ArticleYear
Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-23, Volume: 25, Issue:8

    Topics: Animals; Benztropine; Central Nervous System Stimulants; Cerebellum; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Rats

2005
Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1

    Topics: Animals; Benztropine; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Piperazines

2005