rti 121 has been researched along with amphetamine in 5 studies
| Studies (rti 121) | Trials (rti 121) | Recent Studies (post-2010) (rti 121) | Studies (amphetamine) | Trials (amphetamine) | Recent Studies (post-2010) (amphetamine) |
|---|---|---|---|---|---|
| 64 | 1 | 11 | 13,071 | 329 | 1,977 |
| Protein | Taxonomy | rti 121 (IC50) | amphetamine (IC50) |
|---|---|---|---|
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | 0.96 | |
| Cytochrome P450 2A6 | Homo sapiens (human) | 3.5 | |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | 2.85 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.96 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.96 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abraham, P; Boja, JW; Carroll, FI; Kuhar, MJ; Lever, JR; Parham, K; Scheffel, U; Seltzman, HH; Stathis, M; Thomas, BF; Wyrick, CD | 1 |
| Alexander, M; Burton, NC; Griswold, M; Guilarte, TR; McGlothan, JL; Pham, L; Schneider, JS; Syversen, T; Verina, T; Wong, DF; Zhou, Y | 1 |
| Bordia, T; Huang, LZ; Michael McIntosh, J; Parameswaran, N; Quik, M | 1 |
| Bordia, T; Campos, C; McIntosh, JM; Quik, M | 1 |
| Bevan, M; Davidson, C; Meintel, M; Opacka-Juffry, J; Patel, N; Pinnell, T | 1 |
5 other study(ies) available for rti 121 and amphetamine
| Article | Year |
|---|---|
Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3 beta-(4-[125I]iodophenyl) tropan-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121).
Topics: Amphetamine; Analysis of Variance; Animals; Brain; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Isotope Labeling; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Molecular Structure; Nerve Tissue Proteins; Tissue Distribution | 1996 |
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Macaca fascicularis; Male; Manganese; Parkinsonian Disorders; Positron-Emission Tomography; Substantia Nigra; Synaptic Transmission; Tetrabenazine; Tyrosine 3-Monooxygenase | 2008 |
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Autoradiography; Cocaine; Conotoxins; Corpus Striatum; Cotinine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Iodine Isotopes; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Saimiri; Substantia Nigra; Time Factors | 2009 |
Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization.
Topics: Amphetamine; Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Central Nervous System Stimulants; Cocaine; Conotoxins; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Mecamylamine; Neostriatum; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stereotyped Behavior | 2010 |
Stimulant mechanisms of cathinones - effects of mephedrone and other cathinones on basal and electrically evoked dopamine efflux in rat accumbens brain slices.
Topics: Amphetamine; Amphetamines; Animals; Bupropion; Central Nervous System Stimulants; Cocaine; Diethylpropion; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Electric Stimulation; Iodine Radioisotopes; Male; Methamphetamine; Microelectrodes; Nucleus Accumbens; Propiophenones; Radioligand Assay; Rats, Wistar; Tissue Culture Techniques | 2014 |