Compounds > rti 121
Page last updated: 2024-09-03

rti 121 and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

rti 121 has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 7 studies

Compound Research Comparison

Studies
(rti 121)		Trials
(rti 121)		Recent Studies (post-2010)
(rti 121)		Studies
(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)		Trials
(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)		Recent Studies (post-2010) (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)
641113,85981,052

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
al-Tikriti, MS; Elsworth, JD; Innis, RB; Redmond, DE; Roth, RH; Sladek, JR; Taylor, JR1
Bédard, PJ; Blanchet, PJ; Calon, F; Di Paolo, T; Goulet, M; Grondin, R; Lavertu, N; Lemieux, AM; Morissette, M1
Kulak, JM; McIntosh, JM; Polonskaya, Y; Quik, M1
Kulak, JM; McIntosh, JM; Musachio, JL; Quik, M1
Burton, NC; Guilarte, TR; Kensler, TW1
McIntosh, JM; O'Leary, K; Parameswaran, N; Quik, M1
Bordia, T; Huang, LZ; Michael McIntosh, J; Parameswaran, N; Quik, M1

Other Studies

7 other study(ies) available for rti 121 and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function.
    Experimental neurology, 1994, Volume: 126, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain Tissue Transplantation; Carrier Proteins; Chlorocebus aethiops; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Fetal Tissue Transplantation; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease, Secondary; Radioligand Assay; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra; Transplantation, Heterotopic; Transplantation, Homologous

1994
Effect of MPTP-induced denervation on basal ganglia GABA(B) receptors: correlation with dopamine concentrations and dopamine transporter.
    Synapse (New York, N.Y.), 2001, Jun-01, Volume: 40, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Benzoates; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Organophosphorus Compounds; Parkinsonian Disorders; Protein Subunits; Radioligand Assay; Receptors, GABA-B; RNA, Messenger; Substantia Nigra; Subthalamic Nucleus

2001
Vulnerability of 125I-alpha-conotoxin MII binding sites to nigrostriatal damage in monkey.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Aug-01, Volume: 21, Issue:15

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cocaine; Conotoxins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Habenula; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Neural Pathways; Neurons; Parkinson Disease, Secondary; Putamen; Pyridines; Receptors, Nicotinic; Saimiri; Substantia Nigra

2001
Declines in different beta2* nicotinic receptor populations in monkey striatum after nigrostriatal damage.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Azetidines; Brain Chemistry; Caudate Nucleus; Cocaine; Conotoxins; Neostriatum; Parkinson Disease, Secondary; Putamen; Radioligand Assay; Receptors, Nicotinic; Saimiri; Substantia Nigra

2002
In vivo modulation of the Parkinsonian phenotype by Nrf2.
    Neurotoxicology, 2006, Volume: 27, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antineoplastic Agents; Autoradiography; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Iodine Isotopes; Male; Mice; Mice, Inbred ICR; Mice, Knockout; NF-E2-Related Factor 2; Parkinsonian Disorders; Phenotype; Thiones; Thiophenes

2006
Cotinine selectively activates a subpopulation of alpha3/alpha6beta2 nicotinic receptors in monkey striatum.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Azetidines; Brain; Cocaine; Conotoxins; Cotinine; Dopamine; Dopamine Agents; Female; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Saimiri

2008
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
    Journal of neurochemistry, 2009, Volume: 109, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Autoradiography; Cocaine; Conotoxins; Corpus Striatum; Cotinine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Iodine Isotopes; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Saimiri; Substantia Nigra; Time Factors

2009