Page last updated: 2024-09-05

rs 67333 and td-5108

rs 67333 has been researched along with td-5108 in 28 studies

Compound Research Comparison

Studies
(rs 67333)
Trials
(rs 67333)
Recent Studies (post-2010)
(rs 67333)
Studies
(td-5108)
Trials
(td-5108)
Recent Studies (post-2010) (td-5108)
6303434052216

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (28.57)29.6817
2010's19 (67.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Boulouard, M; Dauphin, F; Lelong, V; Lhonneur, L1
Kemp, A; Manahan-Vaughan, D2
Ishihara, K; Sasa, M1
Cho, S; Hu, Y1
Bisgaard, C; Debonnel, G; Du, J; Haddjeri, N; Lambas-Senas, L; Lucas, G; Manta, S; Mnie-Filali, O; Piñeyro, G; Rymar, VV; Sadikot, AF; Wiborg, O1
Belzung, C; Cachard-Chastel, M; Devers, S; Gardier, AM; Langlois, M; Lezoualc'h, F; Sicsic, S1
Boulouard, M; Dauphin, F; Hotte, M; Levallet, G1
Amraei, MG; Archer-Lahlou, E; Benmbarek, S; Boye, SM; Mnie-Filali, O; Peñas-Cazorla, R; Piñeyro, G; Vilaró, MT1
Debonnel, G; Du, J; Haddjeri, N; Lucas, G; Mnie-Filali, O; Piñeyro, G; Romeas, T1
Chinkwo, KA; Coupar, IM; Grabbe, C; Irving, HR; Li, JG; Pouton, CW; Shapiro, M; Tochon-Danguy, N1
Knudsen, GM; Licht, CL; Sharp, T1
Arregi, A; Azpiroz, A; Beitia, G; Garmendia, L; Gómez-Lázaro, E; Perez-Tejada, J1
Arancio, O; Aziz, F; Hashimoto, G; Saeed, F; Sakurai, M; Teich, AF1
Andreeva, AV; Fukai, T; Hen, R; Krbanjevic, A; Profirovic, J; Strekalova, E; Urao, N; Ushio-Fukai, M; Varadarajan, S; Voyno-Yasenetskaya, TA1
Darcet, F; David, DJ; Gardier, AM; Hen, R; Kerdine-Römer, S; Mendez-David, I; Wu, MV1
Ballandonne, C; Bouet, V; Boulouard, M; Claeysen, S; Corvaisier, S; Cresteil, T; Dallemagne, P; Freret, T; Gaven, F; Giannoni, P; Hedou, D; Lecoutey, C; Malzert Fréon, A; Mignani, S; Rochais, C; Since, M1
Borsotto, M; Bourcier-Lucas, C; Haddjeri, N; Heurteaux, C; Kanzari, A; Lucas, G; Moha ou Maati, H; Veyssiere, J1
Khakpai, F; Nasehi, M; Tabatabaie, M; Zarrindast, MR1
Bouet, V; Boulouard, M; Da Silva Costa-Aze, V; Dallemagne, P; Fabis, F; Freret, T; Hamidouche, K; Nee, G; Quiedeville, A; Rochais, C1
Khodayar, E; Nasehi, M; Oryan, S; Zarrindast, MR1
Darcet, F; David, DJ; Gardier, AM; Guilloux, JP1
Ballandonne, C; Boulouard, M; Dallemagne, P; Davis, A; de Oliveira Santos, JS; Freret, T; Hamidouche, K; Rochais, C; Yahiaoui, S1
Ebrahimi-Ghiri, M; Farrahizadeh, M; Nasehi, M; Zarrindast, MR1
Boulouard, M; Dauphin, F; Freret, T; Hamidouche, K; Lecouflet, P; Lelong-Boulouard, V1
Baranger, K; Bockaert, J; Claeysen, S; Gaven, F; Giannoni, P; Girard, SD; Girot, S; Khrestchatisky, M; Marchetti-Gauthier, E; Migliorati, M; Rivera, S; Roman, FS; Stephan, D1
Agrawal, L; Shiga, T; Vimal, SK1
Eydipour, Z; Jamaldini, SH; Nasehi, M; Vaseghi, S; Zarrindast, MR1

Other Studies

28 other study(ies) available for rs 67333 and td-5108

ArticleYear
BIMU 1 and RS 67333, two 5-HT4 receptor agonists, modulate spontaneous alternation deficits induced by scopolamine in the mouse.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:6

    Topics: Aniline Compounds; Animals; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Locomotion; Male; Memory; Memory Disorders; Mice; Piperidines; Receptors, Serotonin, 5-HT4; Scopolamine; Serotonin 5-HT4 Receptor Agonists

2003
Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, May-25, Volume: 101, Issue:21

    Topics: Aniline Compounds; Animals; Exploratory Behavior; Hippocampus; Learning; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Motor Activity; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists

2004
Failure of repeated electroconvulsive shock treatment on 5-HT4-receptor-mediated depolarization due to protein kinase A system in young rat hippocampal CA1 neurons.
    Journal of pharmacological sciences, 2004, Volume: 95, Issue:3

    Topics: Aniline Compounds; Animals; Cyclic AMP-Dependent Protein Kinases; Electroshock; Hippocampus; In Vitro Techniques; Male; Neurons; Piperazines; Piperidines; Propane; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Second Messenger Systems; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides

2004
The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo.
    Cerebral cortex (New York, N.Y. : 1991), 2005, Volume: 15, Issue:7

    Topics: Aniline Compounds; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Motor Activity; Neuronal Plasticity; Piperidines; Propane; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists

2005
Activation of 5-HT4 receptors inhibits secretion of beta-amyloid peptides and increases neuronal survival.
    Experimental neurology, 2007, Volume: 203, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Mice, Transgenic; Nerve Degeneration; Neurons; Neuroprotective Agents; Peptide Fragments; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists; Synaptic Transmission; Treatment Outcome

2007
Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action.
    Neuron, 2007, Sep-06, Volume: 55, Issue:5

    Topics: Aniline Compounds; Animals; Antidepressive Agents; Brain; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; Disease Models, Animal; Hippocampus; Male; Motor Activity; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT4; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists; Stress, Psychological; Time Factors

2007
Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice.
    Behavioural brain research, 2008, Mar-05, Volume: 187, Issue:2

    Topics: Amyloid beta-Protein Precursor; Analysis of Variance; Aniline Compounds; Animals; Benzofurans; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Drug Synergism; Hippocampus; Indans; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Motor Activity; Nootropic Agents; Piperidines; Scopolamine; Serotonin 5-HT4 Receptor Agonists; Statistics, Nonparametric

2008
Increased particulate phosphodiesterase 4 in the prefrontal cortex supports 5-HT4 receptor-induced improvement of object recognition memory in the rat.
    Psychopharmacology, 2009, Volume: 202, Issue:1-3

    Topics: Aniline Compounds; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Handling, Psychological; Injections, Intraperitoneal; Isoenzymes; Kinetics; Male; Membranes; Memory; Phosphodiesterase Inhibitors; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Recognition, Psychology; Rolipram; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists

2009
Serotonin 4 receptor (5-HT4R) internalization is isoform-specific: effects of 5-HT and RS67333 on isoforms A and B.
    Cellular signalling, 2010, Volume: 22, Issue:3

    Topics: Aniline Compounds; Animals; Antidepressive Agents; Arrestins; beta-Arrestins; Cells, Cultured; Endocytosis; G-Protein-Coupled Receptor Kinase 2; Humans; Neurons; Piperidines; Protein Isoforms; Protein Kinase C; Rats; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Agonists

2010
Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat.
    PloS one, 2010, Feb-16, Volume: 5, Issue:2

    Topics: Action Potentials; Aniline Compounds; Animals; Antidepressive Agents; Benzofurans; CA3 Region, Hippocampal; Citalopram; Cyclic AMP Response Element-Binding Protein; Drug Synergism; Fluvoxamine; Male; Motor Activity; Neurons; Phosphorylation; Piperazines; Piperidines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists

2010
Investigations into the binding affinities of different human 5-HT4 receptor splice variants.
    Pharmacology, 2010, Volume: 85, Issue:4

    Topics: Aniline Compounds; Animals; Benzamides; Benzimidazoles; Benzofurans; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Chlorocebus aethiops; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Indoles; Kinetics; Ligands; Piperidines; Protein Isoforms; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists

2010
Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels.
    Neuroscience letters, 2010, May-31, Volume: 476, Issue:2

    Topics: Aniline Compounds; Animals; Drug Synergism; Extracellular Space; Hippocampus; Hydroxyindoleacetic Acid; Male; Microdialysis; Paroxetine; Piperidines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT4 Receptor Agonists

2010
Effects of a putative antidepressant with a rapid onset of action in defeated mice with different coping strategies.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Aug-07, Volume: 38, Issue:2

    Topics: Adaptation, Psychological; Aniline Compounds; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Dominance-Subordination; Hypothalamus; Interleukin-6; Male; Mice; Piperidines; Receptor, Serotonin, 5-HT1A; Receptors, Glucocorticoid; Serotonin 5-HT4 Receptor Agonists; Spleen; Stress, Psychological; Tumor Necrosis Factor-alpha

2012
5-HT₄ receptor stimulation leads to soluble AβPPα production through MMP-9 upregulation.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 32, Issue:2

    Topics: Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Cell Line; Humans; Matrix Metalloproteinase 9; Mice; Mice, Transgenic; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Up-Regulation

2012
A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor.
    Angiogenesis, 2013, Volume: 16, Issue:1

    Topics: Aniline Compounds; Animals; Capillaries; Cell Adhesion; Cell Membrane Permeability; Cell Movement; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; GTP-Binding Protein alpha Subunits, G12-G13; Human Umbilical Vein Endothelial Cells; Ischemia; Mice; Muscles; Neovascularization, Physiologic; Piperidines; Propane; Receptors, Serotonin, 5-HT4; Regional Blood Flow; rhoA GTP-Binding Protein; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Wound Healing

2013
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:6

    Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Comorbidity; Corticosterone; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Indoles; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides; Time Factors

2014
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Sep-09, Volume: 111, Issue:36

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Chlorocebus aethiops; Cholinesterase Inhibitors; Cognition; COS Cells; Cyclosporine; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Kinetics; Ligands; Mice; Permeability; Piperidines; Receptors, Serotonin, 5-HT4; Rhodamine 123; Serotonin 5-HT4 Receptor Agonists; Solubility; Task Performance and Analysis

2014
The peptidic antidepressant spadin interacts with prefrontal 5-HT(4) and mGluR(2) receptors in the control of serotonergic function.
    Brain structure & function, 2016, Volume: 221, Issue:1

    Topics: Amino Acids; Aniline Compounds; Animals; Antidepressive Agents; Calcium; Dorsal Raphe Nucleus; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Peptides; Piperazines; Piperidines; Potassium Channels, Tandem Pore Domain; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Serotonin, 5-HT4; Serotonergic Neurons; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists; Sulfonamides; Xanthenes

2016
The effects of CA1 5HT4 receptors in MK801-induced amnesia and hyperlocomotion.
    Neuroscience letters, 2015, Feb-05, Volume: 587

    Topics: Amnesia; Aniline Compounds; Animals; CA1 Region, Hippocampal; Dizocilpine Maleate; Drug Partial Agonism; Exploratory Behavior; Male; Memory; Mice; Motor Activity; para-Aminobenzoates; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists

2015
Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances.
    Behavioural brain research, 2015, Oct-15, Volume: 293

    Topics: Analysis of Variance; Aniline Compounds; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Memory; Mice; Motor Activity; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Sulfonamides; Thiophenes; Time Factors

2015
Effect of nucleus accumbens shell 5-HT4 receptors on the impairment of ACPA-induced emotional memory consolidation in male Wistar rats.
    Behavioural pharmacology, 2016, Volume: 27, Issue:1

    Topics: Aniline Compounds; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dose-Response Relationship, Drug; Emotions; Male; Maze Learning; Memory Consolidation; Memory Disorders; Motor Activity; Nootropic Agents; Nucleus Accumbens; Piperidines; Pyrazoles; Random Allocation; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists

2016
Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression.
    Neuroscience letters, 2016, Mar-11, Volume: 616

    Topics: Aniline Compounds; Animals; Antidepressive Agents; Anxiety; Association Learning; Corticosterone; Depression; Fluoxetine; Learning; Male; Memory; Mice, Inbred C57BL; Piperidines; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT4 Receptor Agonists; Spatial Learning; Spatial Memory

2016
Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2016, Oct-04, Volume: 121

    Topics: Alzheimer Disease; Aniline Compounds; Animals; Chemistry Techniques, Synthetic; Drug Design; Guinea Pigs; HEK293 Cells; Humans; Ligands; Male; Mice; Molecular Targeted Therapy; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists

2016
Modulation of cannabinoid signaling by hippocampal 5-HT4 serotonergic system in fear conditioning.
    Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:9

    Topics: Aniline Compounds; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoids; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; Memory; Mice; para-Aminobenzoates; Piperidines; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists

2016
Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse.
    Psychopharmacology, 2017, Volume: 234, Issue:15

    Topics: Allosteric Regulation; Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Galantamine; Male; Memory Disorders; Mice; Nicotinic Antagonists; Piperidines; Receptors, Nicotinic; Receptors, Serotonin, 5-HT4; Scopolamine; Serotonin 5-HT4 Receptor Agonists

2017
Chronic treatments with a 5-HT
    Neuropharmacology, 2017, Volume: 126

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Behavior, Animal; Disease Models, Animal; Encephalitis; Entorhinal Cortex; Learning; Male; Memory; Mice, Transgenic; Neuroglia; Piperidines; Plaque, Amyloid; Serotonin 5-HT4 Receptor Agonists

2017
Role of serotonin 4 receptor in the growth of hippocampal neurons during the embryonic development in mice.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: Aniline Compounds; Animals; Axons; Brain-Derived Neurotrophic Factor; Dendrites; Embryo, Mammalian; Gene Knockdown Techniques; Hippocampus; Indoles; Intercellular Signaling Peptides and Proteins; Mice; Nerve Growth Factor; Nerve Growth Factors; Nerve Tissue Proteins; Neurogenesis; Neurons; Piperidines; Receptors, Serotonin, 5-HT4; RNA, Messenger; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides

2019
The role of 5-HT4 serotonin receptors in the CA1 hippocampal region on memory acquisition impairment induced by total (TSD) and REM sleep deprivation (RSD).
    Physiology & behavior, 2020, 03-01, Volume: 215

    Topics: Aniline Compounds; Animals; Avoidance Learning; CA1 Region, Hippocampal; Male; Memory Consolidation; Memory Disorders; Microinjections; Motor Activity; Pain Perception; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sleep Deprivation

2020