rs 67333 has been researched along with piperidines in 48 studies
| Studies (rs 67333) | Trials (rs 67333) | Recent Studies (post-2010) (rs 67333) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 63 | 0 | 34 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.08) | 18.2507 |
| 2000's | 18 (37.50) | 29.6817 |
| 2010's | 28 (58.33) | 24.3611 |
| 2020's | 1 (2.08) | 2.80 |
| Authors | Studies |
|---|---|
| Cunningham, KA; McMahon, LR | 1 |
| Bockaert, J; Dumuis, A; Marchetti, E; Roman, FS; Soumireu-Mourat, B | 1 |
| Boulouard, M; Dauphin, F; Lelong, V | 1 |
| Lamirault, L; Simon, H | 1 |
| Kulla, A; Manahan-Vaughan, D | 1 |
| Guillou, C; Lamirault, L; Simon, H; Thal, C | 1 |
| Boulouard, M; Dauphin, F; Lelong, V; Lhonneur, L | 1 |
| Kemp, A; Manahan-Vaughan, D | 2 |
| Ishihara, K; Sasa, M | 1 |
| Bockaert, J; Chaillan, FA; Dumuis, A; Marchetti, E; Roman, FS; Soumireu-Mourat, B | 1 |
| Barrot, M; Bockaert, J; Charnay, Y; Compan, V; Debonnel, G; Lucas, G; Nestler, EJ; Neve, RL | 1 |
| Flevari, PG; Iliodromitis, EK; Kremastinos, DT; Leftheriotis, DI; Livanis, EG; Papalois, A; Poulis, D; Theodorakis, GN | 1 |
| Cho, S; Hu, Y | 1 |
| Bisgaard, C; Debonnel, G; Du, J; Haddjeri, N; Lambas-Senas, L; Lucas, G; Manta, S; Mnie-Filali, O; Piñeyro, G; Rymar, VV; Sadikot, AF; Wiborg, O | 1 |
| Belzung, C; Cachard-Chastel, M; Devers, S; Gardier, AM; Langlois, M; Lezoualc'h, F; Sicsic, S | 1 |
| Boulouard, M; Dauphin, F; Hotte, M; Levallet, G | 1 |
| Ikeda, M; Matsumoto, S; Takeda, M; Tsutsui, Y | 1 |
| Dutschmann, M; Manzke, T; Paton, JF; Pickering, AE; Richter, DW; Simms, AE; Waki, H | 1 |
| Amraei, MG; Archer-Lahlou, E; Benmbarek, S; Boye, SM; Mnie-Filali, O; Peñas-Cazorla, R; Piñeyro, G; Vilaró, MT | 1 |
| Conklin, BR; Hsiao, EC; Huang, Y; Louie, A; Millard, SM; Nissenson, RA | 1 |
| Debonnel, G; Du, J; Haddjeri, N; Lucas, G; Mnie-Filali, O; Piñeyro, G; Romeas, T | 1 |
| Chinkwo, KA; Coupar, IM; Grabbe, C; Irving, HR; Li, JG; Pouton, CW; Shapiro, M; Tochon-Danguy, N | 1 |
| Knudsen, GM; Licht, CL; Sharp, T | 1 |
| Castro, E; Díaz, A; Pascual-Brazo, J; Pazos, A; Pilar-Cuéllar, F; Treceño, B; Valdizán, EM; Vidal, R | 1 |
| Bouet, V; Boulouard, M; Dallemagne, P; Freret, T; Nee, G; Quiedeville, A; Rochais, C | 1 |
| Arregi, A; Azpiroz, A; Beitia, G; Garmendia, L; Gómez-Lázaro, E; Perez-Tejada, J | 1 |
| Arancio, O; Aziz, F; Hashimoto, G; Saeed, F; Sakurai, M; Teich, AF | 1 |
| Andreeva, AV; Fukai, T; Hen, R; Krbanjevic, A; Profirovic, J; Strekalova, E; Urao, N; Ushio-Fukai, M; Varadarajan, S; Voyno-Yasenetskaya, TA | 1 |
| Ajjala, DR; Aleti, RR; Bhyrapuneni, G; Kandikere, V; Nirogi, R; Rasheed, MA; Saralaya, R | 1 |
| Darcet, F; David, DJ; Gardier, AM; Hen, R; Kerdine-Römer, S; Mendez-David, I; Wu, MV | 1 |
| Bègue, L; Bell, R; Duke, AA; Gilmore, PE; Page, D | 1 |
| Ballandonne, C; Bouet, V; Boulouard, M; Claeysen, S; Corvaisier, S; Cresteil, T; Dallemagne, P; Freret, T; Gaven, F; Giannoni, P; Hedou, D; Lecoutey, C; Malzert Fréon, A; Mignani, S; Rochais, C; Since, M | 1 |
| Borsotto, M; Bourcier-Lucas, C; Haddjeri, N; Heurteaux, C; Kanzari, A; Lucas, G; Moha ou Maati, H; Veyssiere, J | 1 |
| Khakpai, F; Nasehi, M; Tabatabaie, M; Zarrindast, MR | 1 |
| Kafi, F; Khakpai, F; Nasehi, M; Zarrindast, MR | 1 |
| Bouet, V; Boulouard, M; Da Silva Costa-Aze, V; Dallemagne, P; Fabis, F; Freret, T; Hamidouche, K; Nee, G; Quiedeville, A; Rochais, C | 1 |
| Khodayar, E; Nasehi, M; Oryan, S; Zarrindast, MR | 1 |
| Abboussi, O; El Ganouni, S; Fifel, K; Lakehayli, S; Said, N; Tazi, A | 1 |
| Davoudi, K; Ebrahimi-Ghiri, M; Nasehi, M; Zarrindast, MR | 1 |
| Darcet, F; David, DJ; Gardier, AM; Guilloux, JP | 1 |
| Ballandonne, C; Boulouard, M; Dallemagne, P; Davis, A; de Oliveira Santos, JS; Freret, T; Hamidouche, K; Rochais, C; Yahiaoui, S | 1 |
| Ebrahimi-Ghiri, M; Farrahizadeh, M; Nasehi, M; Zarrindast, MR | 1 |
| Ebrahimi-Ghiri, M; Nasehi, M; Rostam-Nezhad, E; Zarrindast, MR | 1 |
| Boulouard, M; Dauphin, F; Freret, T; Hamidouche, K; Lecouflet, P; Lelong-Boulouard, V | 1 |
| Baranger, K; Bockaert, J; Claeysen, S; Gaven, F; Giannoni, P; Girard, SD; Girot, S; Khrestchatisky, M; Marchetti-Gauthier, E; Migliorati, M; Rivera, S; Roman, FS; Stephan, D | 1 |
| Agrawal, L; Shiga, T; Vimal, SK | 1 |
| Eydipour, Z; Jamaldini, SH; Nasehi, M; Vaseghi, S; Zarrindast, MR | 1 |
48 other study(ies) available for rs 67333 and piperidines
| Article | Year |
|---|---|
Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell.
Topics: 4-Aminobenzoic Acid; Aniline Compounds; Animals; Cocaine; Male; Nucleus Accumbens; para-Aminobenzoates; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Differential modulation of the 5-HT(4) receptor agonists and antagonist on rat learning and memory.
Topics: Aniline Compounds; Animals; Learning; Male; Memory; Pentanones; Piperidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
RS 67333 and D-cycloserine accelerate learning acquisition in the rat.
Topics: Aniline Compounds; Animals; Antimetabolites; Cycloserine; Male; Maze Learning; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists; Stimulation, Chemical | 2001 |
Enhancement of place and object recognition memory in young adult and old rats by RS 67333, a partial agonist of 5-HT4 receptors.
Topics: Aging; Aniline Compounds; Animals; Dose-Response Relationship, Drug; Indoles; Injections, Intraperitoneal; Male; Memory; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Recognition, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2001 |
Modulation by serotonin 5-HT(4) receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats.
Topics: 5-Methoxytryptamine; Aniline Compounds; Animals; Dentate Gyrus; Dose-Response Relationship, Drug; Evoked Potentials; Long-Term Potentiation; Male; Motor Activity; Neural Inhibition; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission | 2002 |
Combined treatment with galanthaminium bromide, a new cholinesterase inhibitor, and RS 67333, a partial agonist of 5-HT4 receptors, enhances place and object recognition in young adult and old rats.
Topics: Age Factors; Aniline Compounds; Animals; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Injections, Intraperitoneal; Male; Memory; Pattern Recognition, Automated; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Task Performance and Analysis | 2003 |
BIMU 1 and RS 67333, two 5-HT4 receptor agonists, modulate spontaneous alternation deficits induced by scopolamine in the mouse.
Topics: Aniline Compounds; Animals; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Locomotion; Male; Memory; Memory Disorders; Mice; Piperidines; Receptors, Serotonin, 5-HT4; Scopolamine; Serotonin 5-HT4 Receptor Agonists | 2003 |
Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition.
Topics: Aniline Compounds; Animals; Exploratory Behavior; Hippocampus; Learning; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Motor Activity; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists | 2004 |
Failure of repeated electroconvulsive shock treatment on 5-HT4-receptor-mediated depolarization due to protein kinase A system in young rat hippocampal CA1 neurons.
Topics: Aniline Compounds; Animals; Cyclic AMP-Dependent Protein Kinases; Electroshock; Hippocampus; In Vitro Techniques; Male; Neurons; Piperazines; Piperidines; Propane; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Second Messenger Systems; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides | 2004 |
The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo.
Topics: Aniline Compounds; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Motor Activity; Neuronal Plasticity; Piperidines; Propane; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2005 |
Modulation of memory processes and cellular excitability in the dentate gyrus of freely moving rats by a 5-HT4 receptors partial agonist, and an antagonist.
Topics: Aniline Compounds; Animals; Dentate Gyrus; Electrodes, Implanted; Electrophysiology; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; Memory; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists.
Topics: Aniline Compounds; Animals; Benzofurans; Electrophysiology; Extracellular Space; Feedback; Frontal Lobe; Gene Transfer Techniques; Genetic Vectors; Herpesvirus 1, Human; In Situ Hybridization; Indoles; Iontophoresis; Male; Neurons; Piperidines; Pyramidal Cells; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; RNA Probes; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2005 |
The effects of 5-HT4 receptor blockade and stimulation, during six hours of atrial fibrillation.
Topics: Aniline Compounds; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiologic Techniques, Cardiac; Heart Rate; Indoles; Male; Piperidines; Refractory Period, Electrophysiological; Serotonin 5-HT4 Receptor Antagonists; Swine | 2005 |
Activation of 5-HT4 receptors inhibits secretion of beta-amyloid peptides and increases neuronal survival.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Mice, Transgenic; Nerve Degeneration; Neurons; Neuroprotective Agents; Peptide Fragments; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists; Synaptic Transmission; Treatment Outcome | 2007 |
Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action.
Topics: Aniline Compounds; Animals; Antidepressive Agents; Brain; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; Disease Models, Animal; Hippocampus; Male; Motor Activity; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT4; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists; Stress, Psychological; Time Factors | 2007 |
Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice.
Topics: Amyloid beta-Protein Precursor; Analysis of Variance; Aniline Compounds; Animals; Benzofurans; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Drug Synergism; Hippocampus; Indans; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Motor Activity; Nootropic Agents; Piperidines; Scopolamine; Serotonin 5-HT4 Receptor Agonists; Statistics, Nonparametric | 2008 |
Increased particulate phosphodiesterase 4 in the prefrontal cortex supports 5-HT4 receptor-induced improvement of object recognition memory in the rat.
Topics: Aniline Compounds; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Handling, Psychological; Injections, Intraperitoneal; Isoenzymes; Kinetics; Male; Membranes; Memory; Phosphodiesterase Inhibitors; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Recognition, Psychology; Rolipram; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists | 2009 |
Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current.
Topics: Aniline Compounds; Animals; Animals, Newborn; Antibodies, Heterophile; Biguanides; Biophysics; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Indoles; Membrane Potentials; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Channel Blockers; Tetrodotoxin; Trigeminal Ganglion; Tropisetron | 2008 |
The potency of different serotonergic agonists in counteracting opioid evoked cardiorespiratory disturbances.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Aniline Compounds; Animals; Blood Pressure; Brain Stem; Cardiovascular Physiological Phenomena; Diaphragm; Electromyography; Fentanyl; Heart; Heart Rate; Histocytochemistry; Phrenic Nerve; Piperidines; Rats; Receptors, Opioid, mu; Serotonin Receptor Agonists; Telemetry; Vascular Resistance | 2009 |
Serotonin 4 receptor (5-HT4R) internalization is isoform-specific: effects of 5-HT and RS67333 on isoforms A and B.
Topics: Aniline Compounds; Animals; Antidepressive Agents; Arrestins; beta-Arrestins; Cells, Cultured; Endocytosis; G-Protein-Coupled Receptor Kinase 2; Humans; Neurons; Piperidines; Protein Isoforms; Protein Kinase C; Rats; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Agonists | 2010 |
Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation.
Topics: Absorptiometry, Photon; Aniline Compounds; Animals; Bone and Bones; Female; Male; Mice; Mice, Transgenic; Osteoblasts; Osteogenesis; Piperidines; Polymerase Chain Reaction; Receptors, G-Protein-Coupled; Serotonin Receptor Agonists; Signal Transduction | 2010 |
Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat.
Topics: Action Potentials; Aniline Compounds; Animals; Antidepressive Agents; Benzofurans; CA3 Region, Hippocampal; Citalopram; Cyclic AMP Response Element-Binding Protein; Drug Synergism; Fluvoxamine; Male; Motor Activity; Neurons; Phosphorylation; Piperazines; Piperidines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2010 |
Investigations into the binding affinities of different human 5-HT4 receptor splice variants.
Topics: Aniline Compounds; Animals; Benzamides; Benzimidazoles; Benzofurans; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Chlorocebus aethiops; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Indoles; Kinetics; Ligands; Piperidines; Protein Isoforms; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists | 2010 |
Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels.
Topics: Aniline Compounds; Animals; Drug Synergism; Extracellular Space; Hippocampus; Hydroxyindoleacetic Acid; Male; Microdialysis; Paroxetine; Piperidines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT4 Receptor Agonists | 2010 |
Modulation of neuroplasticity pathways and antidepressant-like behavioural responses following the short-term (3 and 7 days) administration of the 5-HT₄ receptor agonist RS67333.
Topics: Aniline Compounds; Animals; Antidepressive Agents; Behavior, Animal; Gene Expression Regulation; Hippocampus; Male; Nerve Tissue Proteins; Neural Pathways; Neurogenesis; Neuronal Plasticity; Piperidines; Rats; Rats, Sprague-Dawley | 2012 |
Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice.
Topics: Analysis of Variance; Aniline Compounds; Animals; Behavior, Animal; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Synergism; Indans; Indoles; Male; Mice; Piperidines; Recognition, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2012 |
Effects of a putative antidepressant with a rapid onset of action in defeated mice with different coping strategies.
Topics: Adaptation, Psychological; Aniline Compounds; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Dominance-Subordination; Hypothalamus; Interleukin-6; Male; Mice; Piperidines; Receptor, Serotonin, 5-HT1A; Receptors, Glucocorticoid; Serotonin 5-HT4 Receptor Agonists; Spleen; Stress, Psychological; Tumor Necrosis Factor-alpha | 2012 |
5-HT₄ receptor stimulation leads to soluble AβPPα production through MMP-9 upregulation.
Topics: Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Cell Line; Humans; Matrix Metalloproteinase 9; Mice; Mice, Transgenic; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Up-Regulation | 2012 |
A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor.
Topics: Aniline Compounds; Animals; Capillaries; Cell Adhesion; Cell Membrane Permeability; Cell Movement; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; GTP-Binding Protein alpha Subunits, G12-G13; Human Umbilical Vein Endothelial Cells; Ischemia; Mice; Muscles; Neovascularization, Physiologic; Piperidines; Propane; Receptors, Serotonin, 5-HT4; Regional Blood Flow; rhoA GTP-Binding Protein; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Wound Healing | 2013 |
In-vivo rat striatal 5-HT4 receptor occupancy using non-radiolabelled SB207145.
Topics: Aniline Compounds; Animals; Benzofurans; Binding, Competitive; Brain; Drug Discovery; Indoles; Ligands; Male; Oxazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists; Sulfonamides; Tandem Mass Spectrometry; Tissue Distribution | 2013 |
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Comorbidity; Corticosterone; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Indoles; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides; Time Factors | 2014 |
Anxiolytic-like effects observed in rats exposed to the elevated zero-maze following treatment with 5-HT2/5-HT3/5-HT4 ligands.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Male; Maze Learning; Oxazines; Piperidines; Propane; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides | 2014 |
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Chlorocebus aethiops; Cholinesterase Inhibitors; Cognition; COS Cells; Cyclosporine; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Kinetics; Ligands; Mice; Permeability; Piperidines; Receptors, Serotonin, 5-HT4; Rhodamine 123; Serotonin 5-HT4 Receptor Agonists; Solubility; Task Performance and Analysis | 2014 |
The peptidic antidepressant spadin interacts with prefrontal 5-HT(4) and mGluR(2) receptors in the control of serotonergic function.
Topics: Amino Acids; Aniline Compounds; Animals; Antidepressive Agents; Calcium; Dorsal Raphe Nucleus; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Peptides; Piperazines; Piperidines; Potassium Channels, Tandem Pore Domain; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Serotonin, 5-HT4; Serotonergic Neurons; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists; Sulfonamides; Xanthenes | 2016 |
The effects of CA1 5HT4 receptors in MK801-induced amnesia and hyperlocomotion.
Topics: Amnesia; Aniline Compounds; Animals; CA1 Region, Hippocampal; Dizocilpine Maleate; Drug Partial Agonism; Exploratory Behavior; Male; Memory; Mice; Motor Activity; para-Aminobenzoates; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2015 |
Involvement of the serotonergic system of the ventral hippocampus (CA3) on amnesia induced by ACPA in mice.
Topics: Amnesia; Aniline Compounds; Animals; Arachidonic Acids; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; CA3 Region, Hippocampal; Cannabinoid Receptor Agonists; Catheters, Indwelling; Male; Mice; Oxazines; para-Aminobenzoates; Piperidines; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2015 |
Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances.
Topics: Analysis of Variance; Aniline Compounds; Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Memory; Mice; Motor Activity; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists; Sulfonamides; Thiophenes; Time Factors | 2015 |
Effect of nucleus accumbens shell 5-HT4 receptors on the impairment of ACPA-induced emotional memory consolidation in male Wistar rats.
Topics: Aniline Compounds; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dose-Response Relationship, Drug; Emotions; Male; Maze Learning; Memory Consolidation; Memory Disorders; Motor Activity; Nootropic Agents; Nucleus Accumbens; Piperidines; Pyrazoles; Random Allocation; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists | 2016 |
Behavioral effects of D3 receptor inhibition and 5-HT4 receptor activation on animals undergoing chronic cannabinoid exposure during adolescence.
Topics: Aging; Aniline Compounds; Animals; Anxiety; Behavior, Animal; Cannabinoids; Disease Models, Animal; Dopaminergic Neurons; Indans; Male; Memory; Morpholines; Piperidines; Rats, Wistar; Receptors, Dopamine D3; Receptors, Serotonin, 5-HT4; Schizophrenia; Serotonin 5-HT4 Receptor Antagonists | 2016 |
Interplay between serotonin and cannabinoid function in the amygdala in fear conditioning.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Aniline Compounds; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Male; Memory Disorders; Mice; Microinjections; Piperidines; Reaction Time; Serotonin; Serotonin Agents | 2016 |
Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression.
Topics: Aniline Compounds; Animals; Antidepressive Agents; Anxiety; Association Learning; Corticosterone; Depression; Fluoxetine; Learning; Male; Memory; Mice, Inbred C57BL; Piperidines; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT4 Receptor Agonists; Spatial Learning; Spatial Memory | 2016 |
Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Aniline Compounds; Animals; Chemistry Techniques, Synthetic; Drug Design; Guinea Pigs; HEK293 Cells; Humans; Ligands; Male; Mice; Molecular Targeted Therapy; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin Antagonists | 2016 |
Modulation of cannabinoid signaling by hippocampal 5-HT4 serotonergic system in fear conditioning.
Topics: Aniline Compounds; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoids; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; Memory; Mice; para-Aminobenzoates; Piperidines; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2016 |
Interaction between hippocampal serotonin and cannabinoid systems in reactivity to spatial and object novelty detection.
Topics: Analysis of Variance; Aniline Compounds; Animals; Arachidonic Acids; Cannabinoids; Dose-Response Relationship, Drug; Hippocampus; Locomotion; Male; Mice; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Recognition, Psychology; Serotonin; Serotonin Agents; Signal Detection, Psychological; Spatial Learning | 2017 |
Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse.
Topics: Allosteric Regulation; Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Galantamine; Male; Memory Disorders; Mice; Nicotinic Antagonists; Piperidines; Receptors, Nicotinic; Receptors, Serotonin, 5-HT4; Scopolamine; Serotonin 5-HT4 Receptor Agonists | 2017 |
Chronic treatments with a 5-HT
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Behavior, Animal; Disease Models, Animal; Encephalitis; Entorhinal Cortex; Learning; Male; Memory; Mice, Transgenic; Neuroglia; Piperidines; Plaque, Amyloid; Serotonin 5-HT4 Receptor Agonists | 2017 |
Role of serotonin 4 receptor in the growth of hippocampal neurons during the embryonic development in mice.
Topics: Aniline Compounds; Animals; Axons; Brain-Derived Neurotrophic Factor; Dendrites; Embryo, Mammalian; Gene Knockdown Techniques; Hippocampus; Indoles; Intercellular Signaling Peptides and Proteins; Mice; Nerve Growth Factor; Nerve Growth Factors; Nerve Tissue Proteins; Neurogenesis; Neurons; Piperidines; Receptors, Serotonin, 5-HT4; RNA, Messenger; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides | 2019 |
The role of 5-HT4 serotonin receptors in the CA1 hippocampal region on memory acquisition impairment induced by total (TSD) and REM sleep deprivation (RSD).
Topics: Aniline Compounds; Animals; Avoidance Learning; CA1 Region, Hippocampal; Male; Memory Consolidation; Memory Disorders; Microinjections; Motor Activity; Pain Perception; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sleep Deprivation | 2020 |