rs 67333 has been researched along with donepezil in 5 studies
| Studies (rs 67333) | Trials (rs 67333) | Recent Studies (post-2010) (rs 67333) | Studies (donepezil) | Trials (donepezil) | Recent Studies (post-2010) (donepezil) |
|---|---|---|---|---|---|
| 63 | 0 | 34 | 3,193 | 557 | 1,594 |
| Protein | Taxonomy | rs 67333 (IC50) | donepezil (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 0.4231 | |
| Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | 0.0265 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.022 | |
| Cholinesterase | Homo sapiens (human) | 4.5742 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 7.42 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 5 | |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 7.4 | |
| Acetylcholinesterase | Mus musculus (house mouse) | 1.5489 | |
| Acetylcholinesterase | Homo sapiens (human) | 0.3257 | |
| Acetylcholinesterase | Bos taurus (cattle) | 0.1644 | |
| Choline O-acetyltransferase | Rattus norvegicus (Norway rat) | 0.0053 | |
| Acetylcholinesterase | Rattus norvegicus (Norway rat) | 0.0182 | |
| Beta-secretase 1 | Homo sapiens (human) | 0.8666 | |
| Cholinesterase | Equus caballus (horse) | 3.7325 | |
| Cholinesterase | Mus musculus (house mouse) | 1.992 | |
| Acetylcholine receptor subunit epsilon | Homo sapiens (human) | 0.0324 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.7844 | |
| Acyl-CoA:cholesterol acyltransferase | Oryctolagus cuniculus (rabbit) | 0.008 | |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | 4.715 | |
| Carboxylic ester hydrolase | Equus caballus (horse) | 4.5551 | |
| Histamine H3 receptor | Homo sapiens (human) | 0.35 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ballandonne, C; Bouet, V; Boulouard, M; Claeysen, S; Corvaisier, S; Dallemagne, P; Dauphin, F; Dubost, E; Freret, T; Gaven, F; Genest, D; Giannoni, P; Hamidouche, K; Hedou, D; Lecoutey, C; Legay, R; Malzert-Fréon, A; Rochais, C; Sopkova de Oliveira Santos, J; Yahiaoui, S | 1 |
| Dallemagne, P; Davis, A; Karila, D; Lalut, J; Lecoutey, C; Maurice, T; Nachon, F; Rochais, C; Santoni, G; Silman, I; Sussman, J; Weik, M | 1 |
| Bergamini, C; Bolognesi, ML; Claeysen, S; Dallemagne, P; Davis, A; Hatat, B; Lanthier, C; Lecoutey, C; Liparulo, I; Payan, H; Rochais, C; Since, M | 1 |
| Belzung, C; Cachard-Chastel, M; Devers, S; Gardier, AM; Langlois, M; Lezoualc'h, F; Sicsic, S | 1 |
| Bouet, V; Boulouard, M; Dallemagne, P; Freret, T; Nee, G; Quiedeville, A; Rochais, C | 1 |
5 other study(ies) available for rs 67333 and donepezil
| Article | Year |
|---|---|
Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride.
Topics: Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Computer Simulation; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Ligands; Male; Memory, Short-Term; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Targeted Therapy; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Structure-Activity Relationship; Toxicity Tests, Acute | 2015 |
Novel multitarget-directed ligands targeting acetylcholinesterase and σ
Topics: Acetylcholinesterase; Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Humans; Indoles; Ligands; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Torpedo | 2019 |
Novel multi target-directed ligands targeting 5-HT
Topics: Alzheimer Disease; Animals; Antioxidants; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Ligands; Molecular Structure; Picrates; Reactive Oxygen Species; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Structure-Activity Relationship | 2019 |
Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice.
Topics: Amyloid beta-Protein Precursor; Analysis of Variance; Aniline Compounds; Animals; Benzofurans; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Drug Synergism; Hippocampus; Indans; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Motor Activity; Nootropic Agents; Piperidines; Scopolamine; Serotonin 5-HT4 Receptor Agonists; Statistics, Nonparametric | 2008 |
Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice.
Topics: Analysis of Variance; Aniline Compounds; Animals; Behavior, Animal; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Synergism; Indans; Indoles; Male; Mice; Piperidines; Recognition, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2012 |