rs 67333 has been researched along with donecopride in 4 studies
| Studies (rs 67333) | Trials (rs 67333) | Recent Studies (post-2010) (rs 67333) | Studies (donecopride) | Trials (donecopride) | Recent Studies (post-2010) (donecopride) |
|---|---|---|---|---|---|
| 63 | 0 | 34 | 7 | 0 | 7 |
| Protein | Taxonomy | rs 67333 (IC50) | donecopride (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Homo sapiens (human) | 0.016 | |
| Cholinesterase | Equus caballus (horse) | 3.53 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ballandonne, C; Bouet, V; Boulouard, M; Claeysen, S; Corvaisier, S; Dallemagne, P; Dauphin, F; Dubost, E; Freret, T; Gaven, F; Genest, D; Giannoni, P; Hamidouche, K; Hedou, D; Lecoutey, C; Legay, R; Malzert-Fréon, A; Rochais, C; Sopkova de Oliveira Santos, J; Yahiaoui, S | 1 |
| Chen, Y; Feng, F; He, S; Li, Q; Qu, W; Sun, H | 1 |
| Dallemagne, P; Davis, A; Karila, D; Lalut, J; Lecoutey, C; Maurice, T; Nachon, F; Rochais, C; Santoni, G; Silman, I; Sussman, J; Weik, M | 1 |
| Ballandonne, C; Bouet, V; Boulouard, M; Claeysen, S; Corvaisier, S; Cresteil, T; Dallemagne, P; Freret, T; Gaven, F; Giannoni, P; Hedou, D; Lecoutey, C; Malzert Fréon, A; Mignani, S; Rochais, C; Since, M | 1 |
1 review(s) available for rs 67333 and donecopride
| Article | Year |
|---|---|
Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Drug Discovery; Humans; Indans; Ligands; Molecular Docking Simulation; Oxidative Stress; Piperidines | 2018 |
3 other study(ies) available for rs 67333 and donecopride
| Article | Year |
|---|---|
Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride.
Topics: Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Computer Simulation; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Ligands; Male; Memory, Short-Term; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Targeted Therapy; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Structure-Activity Relationship; Toxicity Tests, Acute | 2015 |
Novel multitarget-directed ligands targeting acetylcholinesterase and σ
Topics: Acetylcholinesterase; Alzheimer Disease; Aniline Compounds; Animals; Cholinesterase Inhibitors; Crystallography, X-Ray; Drug Design; Humans; Indoles; Ligands; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Torpedo | 2019 |
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Chlorocebus aethiops; Cholinesterase Inhibitors; Cognition; COS Cells; Cyclosporine; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Kinetics; Ligands; Mice; Permeability; Piperidines; Receptors, Serotonin, 5-HT4; Rhodamine 123; Serotonin 5-HT4 Receptor Agonists; Solubility; Task Performance and Analysis | 2014 |