rs 45041-190 has been researched along with idazoxan in 4 studies
Studies (rs 45041-190) | Trials (rs 45041-190) | Recent Studies (post-2010) (rs 45041-190) | Studies (idazoxan) | Trials (idazoxan) | Recent Studies (post-2010) (idazoxan) |
---|---|---|---|---|---|
8 | 0 | 2 | 1,499 | 40 | 123 |
Protein | Taxonomy | rs 45041-190 (IC50) | idazoxan (IC50) |
---|---|---|---|
Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0083 | |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0195 | |
Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0537 | |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
Alpha-1A adrenergic receptor | Homo sapiens (human) | 2.884 | |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brown, CM; MacKinnon, AC; Redfern, WS | 1 |
Houghton, AK; Westlund, KN | 1 |
Clarke, RW; Harris, J; Ogilvie, J | 1 |
Choi, DH; Choi, SH; Chun, BG; Lee, JJ; Park, MS | 1 |
4 other study(ies) available for rs 45041-190 and idazoxan
Article | Year |
---|---|
[3H]-RS-45041-190: a selective high-affinity radioligand for I2 imidazoline receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Binding, Competitive; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Imidazoles; Imidazoline Receptors; Indoles; Isoindoles; Kidney; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Drug; Time Factors | 1995 |
An I2 imidazoline ligand, RS 45041, potentiates hyperalgesia in acute arthritis.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Animals; Arthritis; Drug Evaluation, Preclinical; Drug Synergism; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Indoles; Injections, Spinal; Isoindoles; Neural Inhibition; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Drug | 1996 |
Imidazoline I(2)-receptors and spinal reflexes in the decerebrated rabbit.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clorgyline; Decerebrate State; Dose-Response Relationship, Drug; Female; Heart Rate; Idazoxan; Imidazoles; Imidazoline Receptors; Indoles; Injections, Spinal; Isoindoles; Ligands; Male; Monoamine Oxidase Inhibitors; Pargyline; Rabbits; Receptors, Drug; Reflex; Spinal Cord | 2000 |
Imidazoline drugs stabilize lysosomes and inhibit oxidative cytotoxicity in astrocytes.
Topics: Acridine Orange; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Antineoplastic Agents; Apoptosis; Astrocytes; Cathepsin D; Cell Division; Cell Line; Cerebral Cortex; Cytochrome c Group; Fish Venoms; Guanabenz; Guanfacine; HIV Protease Inhibitors; Idazoxan; Imidazoles; Indoles; Isoindoles; L-Lactate Dehydrogenase; Ligands; Lysosomes; Membrane Potentials; Mitochondria; Naphthoquinones; Neuroglia; Oxidation-Reduction; Pepstatins; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Drug | 2002 |