Page last updated: 2024-09-05

rs 127445 and dexfenfluramine

rs 127445 has been researched along with dexfenfluramine in 2 studies

Compound Research Comparison

Studies (rs 127445)	Trials (rs 127445)	Recent Studies (post-2010) (rs 127445)	Studies (dexfenfluramine)	Trials (dexfenfluramine)	Recent Studies (post-2010) (dexfenfluramine)
29	1	18	226	17	20

Protein Interaction Comparison

Protein	Taxonomy	dexfenfluramine (IC50)
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	3.403
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	3.403
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	0.516

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Callebert, J; Drouet, L; Etienne, N; Hervé, P; Humbert, M; Launay, JM; Maroteaux, L; Nebigil, CG; Peoc'h, K; Simonneau, G; Tournois, C	1
Banas, SM; Belmer, A; Boutourlinsky, K; Callebert, J; Collet, C; Diaz, SL; Doly, S; Launay, JM; Maroteaux, L	1

Other Studies

2 other study(ies) available for rs 127445 and dexfenfluramine

Article	Year
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nature medicine, 2002, Volume: 8, Issue:10 Topics: Animals; Blood Pressure; Cell Division; Dexfenfluramine; Disease Models, Animal; DNA; Female; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Organ Culture Techniques; Pulmonary Artery; Pyrimidines; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasoconstriction	2002
Deconstructing antiobesity compound action: requirement of serotonin 5-HT2B receptors for dexfenfluramine anorectic effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:2 Topics: Animals; Appetite Depressants; Appetite Regulation; Dexfenfluramine; Hypothalamus; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Obesity; Pyrimidines; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin Receptor Agonists; Synaptosomes	2011

Article

Year

Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension.

Nature medicine, 2002, Volume: 8, Issue:10

Topics: Animals; Blood Pressure; Cell Division; Dexfenfluramine; Disease Models, Animal; DNA; Female; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Organ Culture Techniques; Pulmonary Artery; Pyrimidines; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasoconstriction

2002

Deconstructing antiobesity compound action: requirement of serotonin 5-HT2B receptors for dexfenfluramine anorectic effects.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:2

Topics: Animals; Appetite Depressants; Appetite Regulation; Dexfenfluramine; Hypothalamus; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Obesity; Pyrimidines; Receptor, Serotonin, 5-HT2B; Serotonin; Serotonin Receptor Agonists; Synaptosomes

2011