rpx7009 and benzeneboronic-acid

rpx7009 has been researched along with benzeneboronic-acid* in 1 studies

Other Studies

1 other study(ies) available for rpx7009 and benzeneboronic-acid

ArticleYear
Serendipitous discovery of aryl boronic acids as β-lactamase inhibitors.
    Bioorganic & medicinal chemistry letters, 2020, 01-15, Volume: 30, Issue:2

    High throughput screening for β-lactamase inhibitors afforded biphenyl hits such as 1. Hit confirmation and X-ray soaking experiments with Pseudomonas Aeruginosa AmpC enzyme led to the identification of an aryl boronic acid-serine complex 4, which was formed from phenyl boronic acid 8 (an impurity in compound 1) and ethylene glycol (the cryoprotectant in the soaking experiment).

    Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Drug Design; Pseudomonas aeruginosa

2020