rpx7009 has been researched along with benzeneboronic-acid* in 1 studies
1 other study(ies) available for rpx7009 and benzeneboronic-acid
Article | Year |
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Serendipitous discovery of aryl boronic acids as β-lactamase inhibitors.
High throughput screening for β-lactamase inhibitors afforded biphenyl hits such as 1. Hit confirmation and X-ray soaking experiments with Pseudomonas Aeruginosa AmpC enzyme led to the identification of an aryl boronic acid-serine complex 4, which was formed from phenyl boronic acid 8 (an impurity in compound 1) and ethylene glycol (the cryoprotectant in the soaking experiment). Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Drug Design; Pseudomonas aeruginosa | 2020 |