Page last updated: 2024-09-04

rpr 100893 and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

rpr 100893 has been researched along with 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one in 3 studies

Compound Research Comparison

Studies
(rpr 100893)
Trials
(rpr 100893)
Recent Studies (post-2010)
(rpr 100893)
Studies
(7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
Trials
(7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
Recent Studies (post-2010) (7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
1310217016

Protein Interaction Comparison

ProteinTaxonomyrpr 100893 (IC50)7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one (IC50)
Substance-P receptorHomo sapiens (human)0.03
Substance-P receptorCavia porcellus (domestic guinea pig)0.032

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bock, MD; Clot, J; Emile, L; Fardin, V; Garret, C; Habert-Ortoli, E; Le Guern, J; Loquet, I; Mercken, L; Pradier, L1
Cavero, I; Floch, A; Thiry, C1
Coupar, IM; Kerr, KP; Mitchelson, F1

Other Studies

3 other study(ies) available for rpr 100893 and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

ArticleYear
Molecular determinants of the species selectivity of neurokinin type 1 receptor antagonists.
    Molecular pharmacology, 1995, Volume: 47, Issue:2

    Topics: Androstanes; Animals; Benzimidazoles; Dipeptides; Humans; Indoles; Isoindoles; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Receptors, Neurokinin-1; Species Specificity; Substance P

1995
Pharmacological evidence that NK-2 tachykinin receptors mediate hypotension in the guinea pig but not in the rat.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4

    Topics: Animals; Benzamides; Blood Pressure; Guinea Pigs; Hypotension; Indoles; Isoindoles; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

1996
Tachykinins play a minor role in mediating the third phase of the contractile response to vagal nerve stimulation of the guinea-pig oesophagus.
    Neuropeptides, 2000, Volume: 34, Issue:1

    Topics: Animals; Benzamides; Electric Stimulation; Esophagus; Guinea Pigs; In Vitro Techniques; Indoles; Isoindoles; Male; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Vagus Nerve

2000