Page last updated: 2024-09-04

rp 73401 and mesopram

rp 73401 has been researched along with mesopram in 4 studies

Compound Research Comparison

Studies
(rp 73401)
Trials
(rp 73401)
Recent Studies (post-2010)
(rp 73401)
Studies
(mesopram)
Trials
(mesopram)
Recent Studies (post-2010) (mesopram)
92023812

Protein Interaction Comparison

ProteinTaxonomyrp 73401 (IC50)mesopram (IC50)
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.42
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.42
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.42
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.42
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.1

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artis, DR; Bollag, G; Card, GL; England, BP; Fong, D; Gillette, S; Ibrahim, PN; Kim, SH; Lee, B; Luu, C; Milburn, MV; Powell, B; Schlessinger, J; Suzuki, Y; Tabrizizad, M; Zhang, KY1
Barlow, DJ; Ehrman, TM; Hylands, PJ1
de Esch, IJ; de Graaf, C; Jansen, C; Kanev, GK; Kooistra, AJ; Leurs, R1
Bao, B; Chedrese, PJ; Clark, A; Fischer, D; Kagan, D; McKenna, SD; Palmer, S; Pietropaolo, M; Tos, EG1

Other Studies

4 other study(ies) available for rp 73401 and mesopram

ArticleYear
Structural basis for the activity of drugs that inhibit phosphodiesterases.
    Structure (London, England : 1993), 2004, Volume: 12, Issue:12

    Topics: Binding Sites; Crystallography, X-Ray; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Structure, Tertiary

2004
In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship

2010
PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design.
    Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15

    Topics: Databases, Protein; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship

2016
Pharmacological inhibition of phosphodiesterase 4 triggers ovulation in follicle-stimulating hormone-primed rats.
    Endocrinology, 2005, Volume: 146, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Benzamides; Chorionic Gonadotropin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Fertility; Follicle Stimulating Hormone; Oocytes; Ovulation; Oxazoles; Phosphodiesterase Inhibitors; Piperazines; Pteridines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, LH

2005