rp 59227 has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turner, NC; Wood, LJ | 1 |
| Asano, M; Hamada, K; Inamura, N; Isono, T; Kohsaka, M; Nagayoshi, A; Nakahara, K; Notsu, Y; Oku, T; Ono, T | 1 |
| Adams, MB; Komorowski, R; McManus, RP; Moore, G; O'Hair, DP; Pieper, GM; Roza, AM | 1 |
| Lewis, SA; Raeburn, D; Underwood, SL | 1 |
| Cavero, I; Floch, A; Sedivy, P; Tahraoui, L | 1 |
| Cavero, I; Floch, A | 1 |
| Bewtra, AK; Eda, R; Gillen, MS; Hopp, RJ; Townley, RG | 1 |
| Auchampach, JA; Cavero, I; Gross, GJ; Pieper, GM | 1 |
1 trial(s) available for rp 59227 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
The effect of RP 59227, a platelet-activating factor antagonist, against antigen challenge and eosinophil and neutrophil chemotaxis in asthmatics.
Topics: Administration, Oral; Adult; Antigens; Asthma; Chemotaxis, Leukocyte; Cross-Over Studies; Double-Blind Method; Eosinophils; Humans; Male; Neutrophils; Platelet Activating Factor; Pyridines; Skin Tests; Thiazoles | 1994 |
7 other study(ies) available for rp 59227 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Characterization of the antagonist activity of the PAF antagonists RP 59227 and WEB 2086 on elicited guinea pig peritoneal macrophages. Evidence for variable affinities and kinetics.
Topics: Animals; Azepines; Guinea Pigs; Humans; Kinetics; Macrophages; Male; Neutrophils; Peritoneum; Platelet Activating Factor; Pyridines; Superoxides; Thiazoles; Triazoles | 1992 |
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Microspheres; Naphthols; Platelet Activating Factor; Prednisolone; Pulmonary Eosinophilia; Pyridines; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Thiazoles | 1992 |
Platelet activating factor antagonist RP-59227 reduces vascular injury in discordant cardiac xenograft rejection.
Topics: Animals; Graft Rejection; Graft Survival; Guinea Pigs; Heart Transplantation; Male; Platelet Activating Factor; Pyridines; Rats; Rats, Inbred Lew; Thiazoles; Transplantation, Heterologous | 1992 |
RP 59227, a novel PAF receptor antagonist: effects in guinea pig models of airway hyperreactivity.
Topics: Animals; Antigens; Azepines; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Pyridines; Thiazoles; Triazoles | 1992 |
The platelet activating factor receptor antagonist, RP 59227, blocks platelet activating factor receptors mediating liberation of reactive oxygen species in guinea pig macrophages and human polymorphonuclear leukocytes.
Topics: Animals; Azepines; Glyceryl Ethers; Guinea Pigs; Humans; Luminescent Measurements; Macrophages; Male; Neutrophils; Oxygen; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles | 1991 |
Influence of plasma protein content and platelet number on the potency of PAF and its antagonist RP 59227 in rabbit platelet preparations.
Topics: Animals; Blood Proteins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Pyridines; Rabbits; Thiazoles | 1990 |
Effect of the platelet-activating factor antagonist RP 59227 (Tulopafant) on myocardial ischemia/reperfusion injury and neutrophil function.
Topics: Animals; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Free Radicals; Incidence; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Neutrophils; Peroxidase; Platelet Activating Factor; Pyridines; Reperfusion Injury; Thiazoles; Ventricular Fibrillation | 1998 |