rp 48740 has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 19 studies
| Studies (rp 48740) | Trials (rp 48740) | Recent Studies (post-2010) (rp 48740) | Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) |
|---|---|---|---|---|---|
| 24 | 0 | 0 | 9,156 | 187 | 552 |
| Protein | Taxonomy | rp 48740 (IC50) | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) |
|---|---|---|---|
| Platelet-activating factor receptor | Homo sapiens (human) | 0.0003 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 9 (47.37) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Claude, JR; Martin, C; Massicot, F; Pham Huy, C; Thevenin, M; Warnet, JM | 1 |
| Bompart, F; Bruno, R; Clucas, A; Gaillot, J; Gregoire, J; Pinquier, JL; Sedivy, P; Strauch, G | 1 |
| Braquet, P; Ferreira, MG; Fonteles, MC | 1 |
| Burrell, R; Keller, GE; Lantz, RC | 1 |
| Freiche, JC; Lang, J; Sedivy, P; Touraine, JL | 1 |
| Breddin, HK; Weichert, W | 1 |
| Benveniste, J; Coëffier, E; Desquand, S; Floch, A; Lefort, J; Maridonneau-Parini, I; Randon, J; Sedivy, P; Vargaftig, BB | 1 |
| Bozza, PT; Cordeiro, RS; Dias, PM; Faria Neto, HC; Lima, MC; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Bureau, M; Joseph, D; Vargaftig, BB | 1 |
| Adnot, S; Joseph, D; Vargaftig, BB | 1 |
| Dechavanne, M; Hanss, M | 1 |
| Myers, AK; Nakanishi, T; Ramwell, P | 1 |
| Beijer, L; Burrell, R; Lantz, RC; Rylander, R; Sedivy, P | 1 |
| Baggiolini, M; Dewald, B | 1 |
| Bousseau, A; Fauci, AS; Poli, G; Weissman, D | 1 |
| Imanishi, N; Koike, H; Morooka, S; Natsume, Y | 1 |
| Bourgain, R; Decuyper, K; van Rossem, K; Vermariën, H | 1 |
| Chignard, M; Paulin, D; Renesto, P; Vicart, P | 1 |
| Bensaid, O; Clayette, P; Dereuddre-Bosquet, N; Dong, CZ; Dormont, D; Godfroid, JJ; Heymans, F; Huet, J; Kan, E; Lamouri, A; Martin, M; Redeuilh, C; Serradji, N | 1 |
19 other study(ies) available for rp 48740 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Inhibitory effects of a platelet activating factor-antagonist 48740RP in cyclosporin-induced nephrotoxicity in the rat as assessed by renal glutathione metabolism parameters.
Topics: Aminopeptidases; Animals; Blood Urea Nitrogen; CD13 Antigens; Creatinine; Cyclosporine; Glutathione; Kidney; Kidney Cortex; Platelet Activating Factor; Pyridines; Rats; Thiazoles | 1991 |
Inhibition of ex-vivo PAF-induced platelet aggregation by the PAF-antagonist RP 48740: relationship to plasma concentrations in healthy volunteers.
Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Humans; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridines; Reference Values; Thiazoles | 1991 |
Effects of PAF antagonists on renal vascular escape and tachyphylaxis in perfused rabbit kidney.
Topics: Animals; Azepines; Diterpenes; Female; Gangliosides; Ginkgolides; In Vitro Techniques; Kidney; Kinetics; Lactones; Male; Perfusion; Platelet Activating Factor; Pyridines; Rabbits; Renal Circulation; Tachyphylaxis; Thiazoles; Time Factors; Triazoles | 1991 |
The role of platelet-activating factor in the pulmonary response to inhaled bacterial endotoxin.
Topics: Animals; Blood Volume; Capillaries; Capillary Permeability; Cricetinae; Endothelium, Vascular; Endotoxins; Enterobacter; Leukocyte Count; Lung; Lung Volume Measurements; Male; Mesocricetus; Platelet Activating Factor; Platelet Count; Pulmonary Alveoli; Pulmonary Edema; Pyridines; Thiazoles | 1991 |
Prolonged survival of renal transplants in nonimmunized and hyperimmunized rats receiving a platelet-activating factor antagonist.
Topics: Animals; Cyclosporins; Cytotoxicity, Immunologic; Graft Rejection; Immunization; Kidney Transplantation; Male; Platelet Activating Factor; Pyridines; Rats; Rats, Inbred BN; Rats, Inbred Lew; Survival Rate; Thiazoles | 1990 |
A PAF-acether antagonist (N 48740 RP/Rhône-Poulenc) and laser-induced thrombi in rat mesenteric vessels.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Lasers; Male; Mesenteric Arteries; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridines; Rats; Rats, Inbred Strains; Thiazoles; Thrombosis | 1989 |
Pharmacological profile of 48740 R.P., a PAF-acether antagonist.
Topics: Animals; Blood Cell Count; Blood Platelets; Bronchodilator Agents; Guinea Pigs; Humans; In Vitro Techniques; Macrophages; Male; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Perfusion; Platelet Activating Factor; Platelet Aggregation; Pulmonary Alveoli; Pyridines; Rabbits; Radioimmunoassay; Superoxides; Thiazoles; Thromboxane B2 | 1988 |
Pharmacological modulation of Paf-induced rat pleurisy and its role in inflammation by zymosan.
Topics: Animals; Azepines; Carrageenan; Leukocyte Count; Male; Platelet Activating Factor; Pleurisy; Pyridines; Rats; Rats, Inbred Strains; Thiazoles; Triazines; Triazoles; Zymosan | 1989 |
Desensitization and antagonism of rat polymorphonuclear leukocytes stimulated with PAF acether.
Topics: Animals; Cells, Cultured; Cytochalasin B; Diterpenes; Exocytosis; Ginkgolides; Glucuronidase; Lactones; Leukotriene B4; Male; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Platelet Activating Factor; Pyridines; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Blood Platelets; Crotalid Venoms; Cyclooxygenase Inhibitors; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Lectins, C-Type; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Pyridines; Thiazoles; Thrombin | 1987 |
48740 RP, an antagonist of PAF, does not affect human plasma fibrinolysis before and after venous occlusion.
Topics: Adult; Constriction; Fibrinolysis; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Pyridines; Thiazoles; Tissue Plasminogen Activator; Veins | 1988 |
Antagonism of PAF-induced death in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Diterpenes; Epinephrine; Fatty Acids, Unsaturated; Furans; Ginkgolides; Hydrazines; Lactones; Male; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thiazoles; Thromboxane A2 | 1988 |
Modulation of pulmonary inflammation after endotoxin inhalation with a platelet-activating factor antagonist (48740 RP).
Topics: Administration, Inhalation; Animals; Capillary Permeability; Cricetinae; Endothelium, Vascular; Endotoxins; Female; Guinea Pigs; Male; Platelet Activating Factor; Pneumonia; Pyridines; Thiazoles | 1988 |
Evaluation of PAF antagonists using human neutrophils in a microtiter plate assay.
Topics: Benzofurans; Diterpenes; Exocytosis; Fluorescence; Ginkgolides; Humans; Lactones; Lignans; Methods; Neutrophils; Pancreatic Elastase; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Pyridines; Thiazoles | 1987 |
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
Topics: Cell Line; Chloramphenicol O-Acetyltransferase; Cytokines; Fluorescent Antibody Technique; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Reverse Transcriptase; HIV-1; Humans; Interleukin-6; Kinetics; Monocytes; Platelet Activating Factor; Pyridines; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA-Directed DNA Polymerase; RNA, Messenger; RNA, Viral; Tetradecanoylphorbol Acetate; Thiazoles; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1993 |
Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils.
Topics: Animals; Azepines; Binding, Competitive; Calcium; Cell Count; Cell Degranulation; Chemotaxis, Leukocyte; Free Radical Scavengers; Inositol 1,4,5-Trisphosphate; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Standards; Signal Transduction; Structure-Activity Relationship; Superoxides; Thiazoles; Thiazolidines; Triazoles; Vitamin E | 1994 |
The role of PAF and the effect of a specific PAF antagonist on local tissue PO2 and neuronal integrity during and after photothrombotic brain infarction in unanesthetised rabbits.
Topics: Animals; Brain; Cerebral Infarction; Disease Models, Animal; Evoked Potentials, Somatosensory; Male; Neurons; Oxygen Consumption; Photobiology; Platelet Activating Factor; Pyridines; Rabbits; Thiazoles; Time Factors | 1996 |
Protective effect of platelet activating factor antagonists on cultured endothelial cell lysis induced by elastase or activated neutrophils.
Topics: Azepines; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Ginkgolides; Humans; Lactones; Leukocyte Elastase; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles | 1996 |
Structure-activity relationships in platelet-activating factor (PAF). 10. From PAF antagonism to inhibition of HIV-1 replication.
Topics: Anti-HIV Agents; Cells, Cultured; HIV; Humans; In Vitro Techniques; Inhibitory Concentration 50; Macrophages; Microbial Sensitivity Tests; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Thiazoles; Virus Replication | 2000 |