Page last updated: 2024-09-05

roxifiban acetate and xv 459

roxifiban acetate has been researched along with xv 459 in 3 studies

Compound Research Comparison

Studies
(roxifiban acetate)
Trials
(roxifiban acetate)
Recent Studies (post-2010)
(roxifiban acetate)
Studies
(xv 459)
Trials
(xv 459)
Recent Studies (post-2010) (xv 459)
8001520

Protein Interaction Comparison

ProteinTaxonomyroxifiban acetate (IC50)xv 459 (IC50)
Integrin beta-3Homo sapiens (human)0.0271
Integrin alpha-IIbHomo sapiens (human)0.0271

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bozarth, J; DeGrado, W; Forsythe, M; Hussain, M; Kapil, R; Lorelli, W; Mousa, SA; Olson, RE; Reilly, TM; Sielecki, TM; Thoolen, MJ; Wexler, R; Wityak, J; Xue, CB1
Bozarth, J; Levine, B; Mousa, SA; Youssef, A1
Barrett, JS; Bozarth, JM; Brown, F; Corjay, MH; Ebling, WF; Kapil, R; Mousa, SA; Padovani, P; Pieniaszek, HJ; Reilly, TM; Yu, J1

Other Studies

3 other study(ies) available for roxifiban acetate and xv 459

ArticleYear
Novel nonpeptide antiplatelet glycoprotein IIb/IIIa receptor antagonist, DMP754: receptor binding affinity and specificity.
    Coronary artery disease, 1996, Volume: 7, Issue:10

    Topics: Amino Acids; Animals; Cell Adhesion; Dogs; Fibrinogen; Guinea Pigs; Humans; Integrins; Isoxazoles; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Rats; Sensitivity and Specificity; Species Specificity

1996
Oral antiplatelet efficacy of the platelet GPIIb/IIIa antagonist, DMP754 in non-human primates.
    Thrombosis research, 1998, Mar-01, Volume: 89, Issue:5

    Topics: Administration, Oral; Amino Acids; Animals; Blood Platelets; Dogs; Drug Evaluation, Preclinical; Humans; Isoxazoles; Kinetics; Papio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex

1998
Disposition and exposure of the fibrinogen receptor antagonist XV459 on alphaIIBbeta3 binding sites in the guinea pig.
    Biopharmaceutics & drug disposition, 1999, Volume: 20, Issue:6

    Topics: Amino Acids; Animals; Area Under Curve; Binding Sites; Binding, Competitive; Guinea Pigs; Humans; Infusions, Intravenous; Isoxazoles; Male; Metabolic Clearance Rate; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Species Specificity; Structure-Activity Relationship

1999