rosmarinic-acid has been researched along with quercitrin* in 2 studies
2 other study(ies) available for rosmarinic-acid and quercitrin
| Article | Year |
|---|---|
The importance of monochromatic lights in the production of phenolic acids and flavonoids in shoot cultures of Aronia melanocarpa, Aronia arbutifolia and Aronia × prunifolia.
Shoot cultures of Aronia melanocarpa, A. arbutifolia and A. × prunifolia were maintained on Murashige and Skoog medium with 1 mg/l each of BA and NAA under monochromatic lights (far-red, red, blue lights, UV-A-irradiation), in darkness, and under white light (control). HPLC-DAD analyses of 19 phenolic acids and 11 flavonoids in methanolic extracts from the shoots revealed in all of them the presence of three depsides (chlorogenic, neochlorogenic and rosmarinic acids), protocatechuic acid, four flavonoid glycosides (cynaroside, quercitrin, hyperoside and rutoside), and additionally, in A. arbutifolia, 3,4-dihydroxyphenylacetic acid. Depending on light quality, the total amounts of these metabolites increased 1.8-5.9 times, reaching maximum values under blue light: 527.40 and 144.61 mg 100 g Topics: Biomass; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Flavonoids; Hydroxybenzoates; Light; Photinia; Plant Shoots; Quercetin; Rosmarinic Acid; Ultraviolet Rays | 2018 |
In vitro and in vivo activity of major constituents from Pluchea carolinensis against Leishmania amazonensis.
The search for new therapeutic agents from natural sources has been a constant for the treatment of diseases such as leishmaniasis. Herein, in vitro and in vivo pharmacological activities of pure major phenolic constituents (caffeic acid, chlorogenic acid, ferulic acid, quercetin, and rosmarinic acid) from Pluchea carolinensis against Leishmania amazonensis are presented. Pure compounds showed inhibitory activity against promastigotes (IC50 = 0.2-0.9 μg/mL) and intracellular amastigotes (IC50 = 1.3-2.9 μg/mL). Four of them were selected after testing against macrophages of BALB/c mice: caffeic acid, ferulic acid, quercetin, and rosmarinic acid, with selective indices of 11, 17, 10, and 20, respectively. Ferulic acid, rosmarinic acid, and caffeic acid controlled lesion size development and parasite burden in footpads from BALB/c experimentally infected mice, after five injections of compounds by intralesional route at 30 mg/kg every 4 days. Pure compounds from P. carolinensis demonstrated antileishmanial properties. Topics: Animals; Antiprotozoal Agents; Asteraceae; Caffeic Acids; Cells, Cultured; Cinnamates; Coumaric Acids; Depsides; Female; Leishmania mexicana; Leishmaniasis; Macrophages; Mice; Mice, Inbred BALB C; Quercetin; Rosmarinic Acid | 2014 |