rosin has been researched along with cobaltous-chloride* in 2 studies
2 other study(ies) available for rosin and cobaltous-chloride
| Article | Year |
|---|---|
Positive concomitant test reactions to allergens in the standard patch test series.
Patch testing is performed to evaluate suspected allergic contact dermatitis. Common wisdom suggests that various allergens cross-react but only a few larger studies have published confirmations of this. The purpose of our study was to identify significant correlations between positive test reactions in a screening series.. A total of 1235 patients undergoing patch testing to the Hermal standard series at the Massachusetts General Hospital, Contact Dermatitis Clinic between 1990 and 2006 were investigated.. Two or more positive reactions were seen in 411 patients (33.3%). Sensitizations to eight pairs of allergens were found to have significant correlation (P Topics: Adult; Allergens; Balsams; Cobalt; Cross Reactions; Dermatitis, Allergic Contact; Female; Formaldehyde; Humans; Male; Methenamine; Middle Aged; Nickel; Patch Tests; Perfume; Potassium Dichromate; Resins, Plant; Urea | 2010 |
Quantification and specificity of the repeated open application test (ROAT). A methodological study using cobalt and colophony in guinea pigs.
The repeated open application test is used to assess the clinical relevance of positive patch test reactions to ingredients of formulated products. The great variation in outcome is usually claimed to be related to the concentration of the allergen responsible. We have here studied the quantitative aspects, specificity and effect of patch testing on the outcome of the repeated open application test in an animal model, using guinea pigs sensitized with cobalt chloride or colophony. Thresholds of sensitivity were determined before and after the topical treatments. Clear dose-response relationships were established. The reactivity in sham-treated controls and to the vehicles was minimal. The concordance between patch test results and outcome of the use tests was concentration-dependent and at low concentrations < 50%. The repeated open application test is a useful method, but some of the basic issues need further evaluation. This animal model will hopefully serve this purpose. Topics: Animals; Antimutagenic Agents; Cobalt; Dermatitis, Allergic Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Patch Tests; Reference Values; Resins, Plant; Sensitivity and Specificity; Tars | 1997 |