Compounds > rosiglitazone
Page last updated: 2024-08-25

rosiglitazone and tyrosine

rosiglitazone has been researched along with tyrosine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's28 (75.68)29.6817
2010's8 (21.62)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Brown, KK; Glass, CK; Li, AC; Palinski, W; Silvestre, MJ; Willson, TM1
Brown, KK; Görgün, CZ; Harrington, WW; Hotamisligil, GS; Kliewer, SA; Oliver, WR; Tong, Q; Uysal, KT; Way, JM; Willson, TM1
Chatterjee, VK; Nugent, C; O'Rahilly, S; Prins, JB; Savage, D; Wentworth, JM; Whitehead, JP1
Hsueh, WA; Kim, S; Kintscher, U; Kuroki, T; Law, RE; Liu, Z; Ohba, M; Schönthal, AH; Wakino, S; Yin, F1
Auwerx, J; Bac, P; Blanchard, SG; Champy, MF; Desreumaux, P; Dubuquoy, L; Gelman, L; Leesnitzer, LM; Moras, D; Picard, F; Plunket, KD; Potier, N; Renaud, JP; Rocchi, S; Vamecq, J; Zeyer, D1
Dey, CS; Kumar, N1
Baker, SF; Brown, J; Davis, B; Hong, G; Khatoon, N1
DeFronzo, RA; He, H; Mandarino, LJ; Miyazaki, Y1
Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Di Rosa, M; Dugo, L; Genovese, T; Ianaro, A; Patel, NS; Pisano, B; Thiemermann, C1
Batinic-Haberle, I; Christopher, TA; Gao, E; Liu, HR; Lopez, BL; Ma, XL; Ohlstein, EH; Tao, L; Teng, ZP; Willette, RN; Yue, TL1
Agostini, M; Chatterjee, VK; Garnes, KT; Gurnell, M; Levinson, SH; O'Rahilly, S; Rajanayagam, O; Savage, DB; Schwabe, JW; Smith, AG; Willson, TM; Wood, EM; Xu, HE1
Britti, D; Caputi, AP; Cuzzocrea, S; De Maio, M; Di Paola, R; Dugo, L; Genovese, T; Mazzon, E; Patel, NS; Serraino, I; Thiemermann, C1
Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Di Rosa, M; Dugo, L; Genovese, T; Ialenti, A; Ianaro, A; Maffia, P; Patel, NS; Pisano, B; Thiemermann, C1
Accili, D; Carnemolla, R; Han, S; Liang, CP; Okamoto, H; Tabas, I; Tall, AR1
Cline, GW; Davies, PJ; Leibowitz, MD; Shen, Q; Shulman, GI1
Chen, J; Chen, Q; Jiang, H; Shen, J; Shen, X; Sun, T1
Kaya, T; Sheu, SH; Vajda, S; Waxman, DJ1
Han, S; Rivera, HN; Roman, J1
Caputi, AP; Catalano, P; Crimi, N; Cuzzocrea, S; Di Paola, R; Genovese, T; Mastruzzo, C; Mazzon, E; Sortino, M; Thiemermann, C; Vancheri, C1
Geng, ZL; Liu, D; Wang, YL; Zeng, BX; Zeng, L; Zhang, SF; Zhang, SH1
Bhatia, M1
Britti, D; Cuzzocrea, S; De Majo, M; Di Paola, R; Genovese, T; Maiere, D; Mazzon, E; Zito, D1
Hur, GY; In, KH; Jung, HC; Jung, KH; Kang, EJ; Kang, KH; Kim, JH; Lee, SY; Shim, JJ; Shin, C; Yoo, SH1
Coales, SJ; Griffin, PR; Hamuro, Y; Molnar, KS; Morrow, JA; Southern, MR; Tuske, SJ1
Díaz-Sanjuán, T; García-Ruiz, I; Martínez, MA; Muñoz-Yagüe, T; Rodríguez-Juan, C; Solís-Herruzo, JA1
Ayaz, L; Emre, M; Günay, I; Inal, T; Kavak, S; Tamer, L1
Bierhaus, A; Bozorgmehr, F; Dugi, K; Hamann, A; Humpert, PM; Ibrahim, Y; Kientsch-Engels, R; Kukudov, G; Morcos, M; Nawroth, PP; Oikomonou, D; Pfisterer, F; Rudofsky, G; Sayed, AA; Schlotterer, A; Schneider, J; Schwenger, V; van der Woude, F; Yard, B; Zeier, M1
Bajirovic, V; Byun, J; Kellogg, A; Oral, E; Pennathur, S; Pop-Busui, R; Raffel, D; Stevens, MJ; Vivekanandan-Giri, A1
Carluccio, MA; De Caterina, R; Distante, A; Massaro, M; Scoditti, E; Storelli, C1
Atherton, RE; Gibbins, JM; Jones, CI; Kaiser, WJ; Moraes, LA; Sage, T; Spyridon, M1
Akahira, J; Hui, XG; Ito, S; Kudo, M; Matsuda, K; Nakamura, Y; Noguchi, N; Okamoto, H; Rainey, WE; Sasano, H; Satoh, F; Sugawara, A; Uruno, A; Yoshikawa, T1
Aggarwal, S; Azakie, A; Black, SM; Datar, SA; Fineman, JR; Fratz, S; Hsu, JH; Kumar, S; Lu, Q; Oishi, PE; Raff, G; Sajti, E; Sharma, S1
Gaekens, M; Gallacher, DJ; Hemmeryckx, B; Lijnen, HR; Lu, HR1
Nakanishi, A; Tsukamoto, I1
Agarwal, AK; Garg, A; Sankella, S1
Al Sharif, M; Alov, P; Diukendjieva, A; Pajeva, I; Tsakovska, I; Vitcheva, V1
Astakhova, AA; Chistyakov, DV; Goriainov, SV; Sergeeva, MG1

Trials

2 trial(s) available for rosiglitazone and tyrosine

ArticleYear
Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.
    Diabetes, 2003, Volume: 52, Issue:8

    Topics: Biopsy; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Secretion; Male; Middle Aged; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Receptor, Insulin; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Tyrosine

2003
Impact of rosiglitazone and glyburide on nitrosative stress and myocardial blood flow regulation in type 2 diabetes mellitus.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:7

    Topics: Adiponectin; Adult; Blood Glucose; C-Reactive Protein; Cohort Studies; Coronary Vessels; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipid Metabolism; Male; Middle Aged; Myocardium; Positron-Emission Tomography; Reactive Nitrogen Species; Rosiglitazone; Thiazolidinediones; Tyrosine; von Willebrand Factor

2009

Other Studies

35 other study(ies) available for rosiglitazone and tyrosine

ArticleYear
Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice.
    The Journal of clinical investigation, 2000, Volume: 106, Issue:4

    Topics: Animals; Arteriosclerosis; Base Sequence; CD36 Antigens; DNA Primers; Female; Gene Expression; Humans; Insulin Resistance; Ligands; Male; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazoles; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, LDL; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Rosiglitazone; Scavenger Receptors, Class B; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine

2000
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.
    The Journal of biological chemistry, 2001, Jul-13, Volume: 276, Issue:28

    Topics: Adipocytes; Animals; Benzophenones; Down-Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine

2001
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:10

    Topics: 3T3 Cells; Adenoviridae; Adipocytes; Animals; Benzophenones; Cell Membrane; Drug Synergism; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Green Fluorescent Proteins; Hypoglycemic Agents; Insulin; Luminescent Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Mutation; Oxazoles; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Tyrosine

2001
Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Acetophenones; Adenoviridae; Animals; Aorta, Thoracic; Apoptosis; Benzopyrans; Blotting, Western; Carbazoles; Cell Division; Cells, Cultured; Chromans; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Hydroquinones; Indoles; Insulin; Isoenzymes; Kinetics; Ligands; Mice; Mitogens; Models, Biological; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tyrosine; Up-Regulation; Vanadates

2001
A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity.
    Molecular cell, 2001, Volume: 8, Issue:4

    Topics: Adipocytes; Amino Acids; Animals; Binding Sites; Blood Glucose; Body Weight; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Fluorenes; Gene Expression Regulation; Genes, Reporter; Hypoglycemic Agents; Insulin Resistance; Leucine; Ligands; Male; Mice; Mice, Inbred Strains; Molecular Structure; Protein Binding; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Spectrometry, Mass, Electrospray Ionization; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Tyrosine

2001
Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells.
    Biochemical pharmacology, 2003, Jan-15, Volume: 65, Issue:2

    Topics: Animals; Biological Transport; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Deoxyglucose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Myoblasts; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pioglitazone; Receptor, Insulin; Rosiglitazone; Thiazoles; Thiazolidinediones; Tyrosine

2003
PPAR gamma-dependent anti-inflammatory action of rosiglitazone in human monocytes: suppression of TNF alpha secretion is not mediated by PTEN regulation.
    Biochemical and biophysical research communications, 2003, Apr-11, Volume: 303, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Monocytes; Morpholines; Oxazoles; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Proteins; Tyrosine

2003
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Animals; Benzhydryl Compounds; Blood Pressure; Epoxy Compounds; Immunologic Factors; Intercellular Adhesion Molecule-1; Interleukin-1; Intestinal Mucosa; Intestines; Ligands; Male; Malondialdehyde; Peroxidase; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Reperfusion Injury; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine; Vasodilator Agents

2003
Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia.
    Circulation, 2003, Dec-02, Volume: 108, Issue:22

    Topics: Animals; Antioxidants; Blood Vessels; Carotid Arteries; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Hypercholesterolemia; In Vitro Techniques; Lipids; Male; Nitrates; Nitric Oxide; Nitrites; Rabbits; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Tyrosine; Vasodilation

2003
Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.
    Endocrinology, 2004, Volume: 145, Issue:4

    Topics: Amino Acid Sequence; Cell Line; Gene Expression; Genes, Dominant; Humans; Leucine; Ligands; Methionine; Models, Structural; Molecular Sequence Data; Monocytes; Mutation; Oxazoles; Pioglitazone; Proline; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Transfection; Tyrosine; Valine

2004
Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma.
    Arthritis and rheumatism, 2003, Volume: 48, Issue:12

    Topics: Animals; Arthritis, Experimental; Collagen Type II; Cyclooxygenase 2; Interleukin-1; Interleukin-6; Isoenzymes; Joints; Lipid Peroxidation; Mice; Mice, Inbred DBA; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine; Vasodilator Agents

2003
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation.
    European journal of pharmacology, 2004, Jan-01, Volume: 483, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Cytokines; Dinoprostone; Edema; Exudates and Transudates; Immunohistochemistry; Isoenzymes; Lipid Peroxidation; Lung; Male; Neutrophil Infiltration; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Pleurisy; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tyrosine

2004
Increased CD36 protein as a response to defective insulin signaling in macrophages.
    The Journal of clinical investigation, 2004, Volume: 113, Issue:5

    Topics: Animals; Blotting, Northern; Blotting, Western; CD36 Antigens; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Foam Cells; Glutathione; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipoproteins, LDL; Macrophages; Mice; Mice, Inbred C57BL; Mice, Obese; Morpholines; Oxygen; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Signal Transduction; Thiazolidinediones; Time Factors; Transcription Factors; Transcription, Genetic; Tyrosine

2004
Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice.
    The Journal of biological chemistry, 2004, May-07, Volume: 279, Issue:19

    Topics: Acyl Coenzyme A; Animals; Anticholesteremic Agents; Biological Transport; Blotting, Western; Body Weight; Cattle; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Resistance; Ligands; Ligases; Mice; Muscle, Skeletal; Muscles; Organic Chemicals; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-cbl; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Triglycerides; Tyrosine; Ubiquitin-Protein Ligases

2004
A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.
    Analytical biochemistry, 2004, Dec-15, Volume: 335, Issue:2

    Topics: alpha-Galactosidase; Anilides; Cells, Cultured; Chromans; CREB-Binding Protein; Drug Evaluation, Preclinical; Genes, Reporter; Indomethacin; Ligands; Nuclear Proteins; Oxazoles; Pioglitazone; PPAR gamma; Prostaglandin D2; Protein Binding; Rosiglitazone; Thiazolidinediones; Trans-Activators; Troglitazone; Two-Hybrid System Techniques; Tyrosine; Yeasts

2004
Exploring the binding site structure of the PPAR gamma ligand-binding domain by computational solvent mapping.
    Biochemistry, 2005, Feb-01, Volume: 44, Issue:4

    Topics: Alkanesulfonates; Binding Sites; Cinnamates; Computational Biology; Humans; Ligands; Oxazines; Oxazoles; Phenylpropionates; PPAR gamma; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Rosiglitazone; Solvents; Thiazoles; Thiazolidinediones; Thiazolidines; Tyrosine

2005
Peroxisome proliferator-activated receptor-gamma ligands inhibit alpha5 integrin gene transcription in non-small cell lung carcinoma cells.
    American journal of respiratory cell and molecular biology, 2005, Volume: 32, Issue:4

    Topics: Base Sequence; Benzophenones; Binding Sites; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Integrin alpha5; Ligands; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Tyrosine

2005
Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury.
    The European respiratory journal, 2005, Volume: 25, Issue:2

    Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Biopsy; Bleomycin; Epoxy Compounds; Immunoenzyme Techniques; Instillation, Drug; Male; Mice; Nitric Oxide Synthase; Peroxidase; Poly(ADP-ribose) Polymerases; Prostaglandin D2; Pulmonary Fibrosis; Random Allocation; Rosiglitazone; Thiazolidinediones; Tyrosine; Weight Loss

2005
Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, reduces acute lung injury in endotoxemic rats.
    Critical care medicine, 2005, Volume: 33, Issue:10

    Topics: Anilides; Animals; Endotoxemia; Lipopolysaccharides; Lung; Male; Nitric Oxide; Nitric Oxide Synthase Type II; PPAR gamma; Rats; Rats, Wistar; Respiratory Distress Syndrome; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tyrosine

2005
Peroxisome proliferator-activated receptor-gamma ligands protect against lung injury: potential therapeutic targets?
    Critical care medicine, 2005, Volume: 33, Issue:10

    Topics: Animals; Humans; Lung; Nitric Oxide; Nitric Oxide Synthase Type II; PPAR gamma; Rats; Respiratory Distress Syndrome; Rosiglitazone; Thiazolidinediones; Tyrosine

2005
Rosiglitazone reduces the evolution of experimental periodontitis in the rat.
    Journal of dental research, 2006, Volume: 85, Issue:2

    Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ligation; Male; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Periodontitis; Poly(ADP-ribose) Polymerase Inhibitors; PPAR gamma; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones; Tyrosine

2006
Peroxisome proliferator-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:1

    Topics: Carcinoma, Mucoepidermoid; Cell Line, Tumor; Down-Regulation; Enzyme Inhibitors; ErbB Receptors; Humans; Hypoglycemic Agents; Lung Neoplasms; Mucin 5AC; Mucins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Respiratory Mucosa; Rosiglitazone; Smoking; Thiazolidinediones; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins

2006
Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators.
    Protein science : a publication of the Protein Society, 2006, Volume: 15, Issue:8

    Topics: Amides; Amino Acid Sequence; Anilides; Benzophenones; Binding Sites; Deuterium Exchange Measurement; Indoles; Ligands; Mass Spectrometry; Models, Molecular; Pepsin A; Peptide Fragments; PPAR gamma; Protein Conformation; Protein Structure, Tertiary; Rosiglitazone; Sulfides; Thiazolidinediones; Tyrosine

2006
Effects of rosiglitazone on the liver histology and mitochondrial function in ob/ob mice.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Fatty Liver; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Microscopy, Electron; Mitochondria, Liver; PPAR gamma; Rosiglitazone; Thiazolidinediones; Tyrosine

2007
The effects of rosiglitazone on oxidative stress and lipid profile in left ventricular muscles of diabetic rats.
    Cell biochemistry and function, 2008, Volume: 26, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Heart Ventricles; Lipid Metabolism; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Rosiglitazone; Streptozocin; Thiazolidinediones; Tyrosine

2008
Rosiglitazone reduces angiotensin II and advanced glycation end product-dependent sustained nuclear factor-kappaB activation in cultured human proximal tubular epithelial cells.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2008, Volume: 40, Issue:11

    Topics: Angiotensin II; Cell Nucleus; Cells, Cultured; Diabetic Nephropathies; Epithelial Cells; Gene Expression; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Kidney Tubules, Proximal; NF-kappa B; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Rosiglitazone; Thiazolidinediones; Tyrosine

2008
PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.
    Cardiovascular research, 2010, May-01, Volume: 86, Issue:2

    Topics: Angiogenesis Inhibitors; Anilides; Benzhydryl Compounds; Benzophenones; Binding Sites; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Down-Regulation; Endothelial Cells; Epoxy Compounds; Gene Expression Regulation, Enzymologic; Humans; Neovascularization, Physiologic; Nitrobenzenes; PPAR gamma; Promoter Regions, Genetic; Protein Kinase C-alpha; Protein Transport; RNA Interference; RNA, Messenger; Rosiglitazone; Sulfonamides; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transfection; Tyrosine; Vascular Endothelial Growth Factor A

2010
Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Anilides; Animals; Blood Platelets; Calcium; Collagen; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Phosphorylation; Platelet Aggregation; Platelet Endothelial Cell Adhesion Molecule-1; Platelet Membrane Glycoproteins; PPAR gamma; Prostaglandin D2; Protein-Tyrosine Kinases; Rosiglitazone; Signal Transduction; Spectrometry, Fluorescence; Syk Kinase; Thiazolidinediones; Thrombosis; Time Factors; Tyrosine

2010
Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production.
    Journal of molecular endocrinology, 2011, Volume: 46, Issue:1

    Topics: Adrenal Cortex; Aldosterone; Benzophenones; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line; Cytochrome P-450 CYP11B2; Gene Expression; Gene Expression Regulation, Enzymologic; Humans; Ionomycin; Mutation; Pioglitazone; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Sulfonamides; Thiazolidinediones; Transcription, Genetic; Tyrosine; Zona Glomerulosa

2011
Rosiglitazone preserves pulmonary vascular function in lambs with increased pulmonary blood flow.
    Pediatric research, 2013, Volume: 73, Issue:1

    Topics: Acetylcholine; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Hemodynamics; NADPH Oxidases; Nitric Oxide; PPAR gamma; Pulmonary Circulation; Pulmonary Wedge Pressure; rac1 GTP-Binding Protein; Rosiglitazone; Sheep; Superoxide Dismutase; Thiazolidinediones; Tyrosine; Vascular Resistance

2013
Effect of rosiglitazone on liver structure and function in genetically diabetic Akita mice.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:5

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Cholesterol, Dietary; Diabetes Mellitus; Diet, High-Fat; Fatty Liver; Gene Expression; Genotype; Liver; Male; Mice; Mice, Inbred C57BL; Organ Size; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Triglycerides; Tyrosine

2013
n-3 polyunsaturated fatty acids stimulate osteoclastogenesis through PPARγ-mediated enhancement of c-Fos expression, and suppress osteoclastogenesis through PPARγ-dependent inhibition of NFkB activation.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:11

    Topics: Animals; Benzophenones; Bone Marrow Cells; Cells, Cultured; Cyclooxygenase 2; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Gene Expression Regulation; Male; Mesenchymal Stem Cells; NF-kappa B; Osteogenesis; PPAR gamma; Proto-Oncogene Proteins c-fos; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tyrosine

2015
Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Acyltransferases; Anilides; Animals; Blotting, Northern; Caco-2 Cells; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Computational Biology; HT29 Cells; Humans; Kidney Tubules, Proximal; Liver; Mice; Oxazoles; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sulfones; Thiazoles; Thiazolidinediones; Thiophenes; Tyrosine

2016
Molecular Modeling Approach to Study the PPARγ-Ligand Interactions.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1966

    Topics: Humans; Hypoglycemic Agents; Ligands; Molecular Docking Simulation; Oxazoles; PPAR gamma; Protein Conformation; Quantitative Structure-Activity Relationship; Rosiglitazone; Tyrosine

2019
Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in Astrocytes.
    International journal of molecular sciences, 2020, Dec-16, Volume: 21, Issue:24

    Topics: Anilides; Animals; Anti-Inflammatory Agents; Astrocytes; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fenofibrate; Interleukin-10; Lipopolysaccharides; MAP Kinase Kinase 4; Oxazoles; Oxylipins; p38 Mitogen-Activated Protein Kinases; PPAR gamma; PPAR-beta; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Tumor Necrosis Factor-alpha; Tyrosine

2020