rosiglitazone has been researched along with tretinoin in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (12.77) | 18.2507 |
| 2000's | 24 (51.06) | 29.6817 |
| 2010's | 16 (34.04) | 24.3611 |
| 2020's | 1 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Gege, C; Hoffmann, T; Schlüter, T | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gellrich, L; Heering, J; Kaiser, A; Kalinowsky, L; Kilu, W; Merk, D; Ohrndorf, J; Pollinger, J; Proschak, E; Schierle, S; Schmidt, J | 1 |
| Lazar, MA; Shao, D | 1 |
| Alvarez, JG; Evans, RM; Nagy, L; Thomazy, VA; Tontonoz, P | 1 |
| Albrektsen, T; Gustafsson, JA; Johansson, L; Leers, J; Treuter, E | 1 |
| Burris, TP; Cryan, E; Demarest, KT; Osborne, MC; Pelton, PD; Zhou, L | 1 |
| Aviram, M; Bisgaier, CL; Newton, RS; Zhu, L | 1 |
| Clapham, JC; Smith, SA; Teruel, T | 1 |
| Bledsoe, RK; Gampe, RT; Kliewer, SA; Lambert, MH; Milburn, MV; Miller, AB; Montana, VG; Willson, TM; Xu, HE | 1 |
| Eriksson, U; Hansson, GK; Romert, A; Sirsjö, A; Törmä, H; Wuttge, DM | 1 |
| Blumentrath, J; Neye, H; Verspohl, EJ | 1 |
| Ailhaud, G; Amri, EZ; Belmonte, N; Dani, C; Iehlé, C; Milstone, DS; Mortensen, RM; O'Donnell, PE; Phillips, B; Vernochet, C; Villageois, P; Wdziekonski, B | 1 |
| Chicheportiche, R; Dayer, JM; Dreyer, MG; Juge-Aubry, CE; Meier, CA | 1 |
| Benito, M; Hernandez, R; Lorenzo, M; Teruel, T | 1 |
| Elstner, E; Fenner, MH; Liu, H; Possinger, K; Zang, C | 1 |
| Ahn, IS; Do, MS; Hong, SE; Jung, HS; Rayner, DV | 1 |
| Akerblad, P; Améen, C; Asp, L; Edvardsson, U; Lindén, D; Ljungberg, A; Olofsson, SO; Oscarsson, J; Tuneld, A | 1 |
| Camacho, IE; De Strooper, B; Dominguez, D; Merchiers, P; Serneels, L; Spittaels, K | 1 |
| Allred, CD; Kilgore, MW | 1 |
| Giralt, M; Hondares, E; Iglesias, R; Mora, O; Rodriguez de la Concepción, M; Villarroya, F; Yubero, P | 1 |
| Caguyong, MJ; Cornwell, PD; Dai, X; De Souza, AT; Ulrich, RG | 1 |
| Elo, B; Govorko, D; Villano, CM; White, LA | 1 |
| Aeed, H; Bruck, R; Halpern, Z; Pines, M; Weiss, S; Zvibel, I | 1 |
| Dushkin, MI; Khoshchenko, OM; Posokhova, EN; Schvarts, YSh | 1 |
| Dong, YW; Wang, XP; Wu, K | 1 |
| Hammond, GL; Selva, DM | 1 |
| Chen, G; Fu, J; Huang, H; Wu, D | 1 |
| Chang, W; Chen, G; Chow, HC; Fu, J; Huang, H; Leung, AY; Liang, R; Wu, D | 1 |
| Andò, S; Bonofiglio, D; Catalano, S; Cione, E; Fuqua, SA; Genchi, G; Panno, ML; Perri, M; Pingitore, A; Qi, H; Vizza, D | 1 |
| Chang, HR; Chen, GH; Chow, HC; Huang, HW; Leung, AY; Liang, R; Wu, DP | 2 |
| Andò, S; Bonofiglio, D; Catalano, S; Cione, E; Genchi, G; Perri, M; Pingitore, A; Qi, H; Rovito, D; Vizza, D | 1 |
| Baharvand, H; Esmaeili, A; Ghaedi, K; Ghoochani, A; Hashemi, M; Karamali, F; Karbalaei, K; Nasr-Esfahani, MH; Peymani, M; Salamian, A; Shabani, K; Tanhaie, S; Valian-Borujeni, S | 1 |
| Chen, DX; Fang, N; Gong, QH; Ma, JJ; Yu, LM; Zhang, T; Zou, Y | 1 |
| Chen, P; Chow, HC; Fan, YY; Fu, JX; Huang, HW; Leung, AY; Li, BZ; Li, J; Liang, R; Liu, R; Zhang, H; Zhang, XH | 1 |
| Aoki, A; Hiromori, Y; Ido, A; Kimura, T; Nagase, H; Nakanishi, T | 1 |
| Chen, QZ; Deng, ZL; He, BC; Li, Y; Liu, RX; Ren, WY; Shao, Y; Sun, WJ; Wu, K; Yang, JQ; Yu, Y; Zeng, YH; Zhou, LY | 1 |
| Endo, S; Furukawa, C; Hasegawa, H; Ikari, A; Manabe, A; Matsunaga, T | 1 |
| Hang, H; Ren, SY; Song, AJ; Wang, LK; Wu, GF | 1 |
1 review(s) available for rosiglitazone and tretinoin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
46 other study(ies) available for rosiglitazone and tretinoin
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Identification of the first inverse agonist of retinoid-related orphan receptor (ROR) with dual selectivity for RORβ and RORγt.
Topics: Benzeneacetamides; Drug Inverse Agonism; Fluorescence Resonance Energy Transfer; Humans; Ligands; Nuclear Receptor Subfamily 1, Group F, Member 2; Nuclear Receptor Subfamily 1, Group F, Member 3; Protein Binding; Th17 Cells; Thiazoles; Tretinoin | 2014 |
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.
Topics: Animals; HEK293 Cells; Hep G2 Cells; Humans; Male; Mice, Inbred C57BL; Microsomes, Liver; Molecular Structure; Peroxisome Proliferator-Activated Receptors; Pyrimidines; Rats; Retinoid X Receptors; Structure-Activity Relationship | 2019 |
Peroxisome proliferator activated receptor gamma, CCAAT/enhancer-binding protein alpha, and cell cycle status regulate the commitment to adipocyte differentiation.
Topics: 3T3 Cells; Adipocytes; Animals; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cell Cycle; Cell Differentiation; DNA-Binding Proteins; Mice; Nuclear Proteins; Receptors, Cytoplasmic and Nuclear; Retinoblastoma Protein; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 1997 |
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL.
Topics: Alitretinoin; Animals; Arteriosclerosis; CD36 Antigens; Cell Differentiation; Dimerization; Foam Cells; HL-60 Cells; Humans; Ligands; Lipoproteins, LDL; Macrophages; Membrane Proteins; Mice; Mice, Transgenic; Monocytes; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Retinoic Acid; Receptors, Scavenger; Retinoid X Receptors; Rosiglitazone; Scavenger Receptors, Class B; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Tretinoin | 1998 |
A regulatory role for RIP140 in nuclear receptor activation.
Topics: Adaptor Proteins, Signal Transducing; Alitretinoin; Amino Acid Sequence; Animals; Binding, Competitive; Cell Nucleus; Cloning, Molecular; Dimerization; DNA-Binding Proteins; Fatty Acids; Gene Expression Regulation; Gene Library; Histone Acetyltransferases; Humans; Macromolecular Substances; Molecular Sequence Data; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivators; Nuclear Receptor Interacting Protein 1; Oncogene Proteins; Pyrimidines; Rabbits; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Recombinant Fusion Proteins; Repressor Proteins; Retinoid X Receptors; Rosiglitazone; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin; Zinc Fingers | 1998 |
A novel method for analysis of nuclear receptor function at natural promoters: peroxisome proliferator-activated receptor gamma agonist actions on aP2 gene expression detected using branched DNA messenger RNA quantitation.
Topics: Adipocytes; Animals; Base Sequence; Carrier Proteins; Cells, Cultured; Chromans; Diabetes Mellitus; DNA Probes; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Female; Gene Expression Regulation; Genetic Techniques; Humans; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Sequence Data; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tretinoin; Troglitazone; Tumor Suppressor Proteins | 1999 |
9-cis retinoic acid induces monocyte chemoattractant protein-1 secretion in human monocytic THP-1 cells.
Topics: Alitretinoin; Blood Cells; Chemokine CCL2; Dose-Response Relationship, Drug; Humans; Monocytes; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1999 |
PPARalpha activation by Wy 14643 induces transactivation of the rat UCP-1 promoter without increasing UCP-1 mRNA levels and attenuates PPARgamma-mediated increases in UCP-1 mRNA levels induced by rosiglitazone in fetal rat brown adipocytes.
Topics: Adipose Tissue, Brown; Alitretinoin; Animals; Carrier Proteins; Cells, Cultured; Gene Expression Regulation; Ion Channels; Membrane Proteins; Mitochondrial Proteins; Peroxisome Proliferators; Promoter Regions, Genetic; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tretinoin; Uncoupling Protein 1 | 1999 |
Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors.
Topics: Alitretinoin; Amino Acid Sequence; Binding Sites; Crystallography; Diabetes Mellitus, Type 2; Dimerization; Drug Design; Histone Acetyltransferases; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Nuclear Receptor Coactivator 1; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Sequence Homology, Amino Acid; Surface Properties; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 2000 |
Induction of CD36 by all-trans retinoic acid: retinoic acid receptor signaling in the pathogenesis of atherosclerosis.
Topics: Arteriosclerosis; CD36 Antigens; Cell Line; Cells, Cultured; Fibrinolytic Agents; Gene Expression Regulation; Humans; Lipoproteins, LDL; Monocytes; Muscle, Smooth, Vascular; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 2001 |
Effects of retinoids and thiazolidinediones on proliferation, insulin release, insulin mRNA, GLUT 2 transporter protein and mRNA of INS-1 cells.
Topics: Alitretinoin; Animals; Binding Sites; Blotting, Northern; Blotting, Western; Cell Division; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Glucose; Glucose Transporter Type 2; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Monosaccharide Transport Proteins; Proinsulin; Protein Precursors; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Tretinoin | 2001 |
PPARgamma-dependent and PPARgamma-independent effects on the development of adipose cells from embryonic stem cells.
Topics: Adipocytes; Animals; Biomarkers; Cell Differentiation; Cell Lineage; Cells, Cultured; Gene Expression; HMGA2 Protein; Lipoprotein Lipase; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Stem Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 2002 |
Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Line; Cell Separation; Enzyme Inhibitors; Fibrinolytic Agents; Flow Cytometry; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Ligands; Monocytes; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Sialoglycoproteins; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Tretinoin; Tumor Necrosis Factor-alpha; Up-Regulation; Vitamin D | 2002 |
Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Carrier Proteins; Cells, Cultured; Culture Media, Serum-Free; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Fetus; Gene Expression Regulation; Genes, Reporter; Glutathione; Imidazoles; Ion Channels; Membrane Proteins; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Rats; Rats, Wistar; Recombinant Fusion Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Tretinoin; Uncoupling Agents; Uncoupling Protein 1 | 2003 |
PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro.
Topics: Breast Neoplasms; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nuclear Proteins; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Tissue Inhibitor of Metalloproteinases; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 2003 |
Effect of retinoic acid on leptin, glycerol, and glucose levels in mature rat adipocytes in vitro.
Topics: Adipocytes; Alitretinoin; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation; Glycerol; Isomerism; Leptin; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; Retinoid X Receptors; Rosiglitazone; Thiazolidinediones; Tretinoin | 2004 |
Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver.
Topics: Alitretinoin; Animals; Apolipoproteins B; Carrier Proteins; Cell Line; Cells, Cultured; Dactinomycin; Gene Expression Regulation; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Tretinoin | 2005 |
Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anilides; Animals; Aspartic Acid Endopeptidases; Cell Line; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Chromans; Culture Media, Conditioned; Endopeptidases; Humans; Kidney; Mice; Neuroblastoma; Neuroglia; Neurons; Peptide Fragments; Pioglitazone; PPAR gamma; Protein Processing, Post-Translational; Receptor, Notch1; Receptors, Cell Surface; Recombinant Fusion Proteins; Retinoid X Receptors; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tretinoin; Troglitazone | 2004 |
Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.
Topics: Alitretinoin; Anilides; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; HT29 Cells; Humans; Ligands; Lung Neoplasms; PPAR gamma; Prostaglandin D2; Retinoid X Receptor alpha; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transfection; Tretinoin | 2005 |
Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coacti
Topics: 3T3-L1 Cells; Adipocytes; Alitretinoin; Animals; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Homeostasis; Hypoglycemic Agents; Mice; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Response Elements; Rosiglitazone; Thiazolidinediones; Trans-Activators; Transcription Factors; Transcriptional Activation; Tretinoin | 2006 |
Agonists of the peroxisome proliferator-activated receptor alpha induce a fiber-type-selective transcriptional response in rat skeletal muscle.
Topics: Animals; Bezafibrate; Fatty Acids; Female; Fenofibrate; Gene Expression Profiling; Glucose; Hypolipidemic Agents; Liver; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; PPAR alpha; Pyrimidines; Rats; Rats, Inbred Strains; Rosiglitazone; Thiazolidinediones; Tretinoin | 2006 |
Larval zebrafish as a model for glucose metabolism: expression of phosphoenolpyruvate carboxykinase as a marker for exposure to anti-diabetic compounds.
Topics: Animals; Blood Glucose; Cyclic AMP; Dexamethasone; Glipizide; Hypoglycemic Agents; Larva; Metformin; Models, Animal; Phosphoenolpyruvate Carboxykinase (GTP); Rosiglitazone; Thiazolidinediones; Tretinoin; Zebrafish | 2007 |
Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor.
Topics: Alitretinoin; Animals; Cell Proliferation; Collagen Type I; Cytokines; Drug Synergism; Hepatic Stellate Cells; Liver Cirrhosis, Experimental; Male; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Thioacetamide; Tretinoin | 2009 |
Agonists of PPAR-alpha, PPAR-gamma, and RXR inhibit the formation of foam cells from macrophages in mice with inflammation.
Topics: Alitretinoin; Animals; Bezafibrate; Cholesterol; Cholesterol Esters; Foam Cells; Inflammation; Injections, Intraperitoneal; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; PPAR alpha; PPAR gamma; Retinoid X Receptors; Rosiglitazone; Thiazolidinediones; Tretinoin; Triglycerides; Tumor Necrosis Factor-alpha; Zymosan | 2007 |
Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition.
Topics: Animals; Base Sequence; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Pancreatic Neoplasms; PPAR gamma; Prostaglandin D2; Retinoid X Receptor alpha; RNA, Messenger; RNA, Neoplasm; Rosiglitazone; Thiazolidinediones; Transplantation, Heterologous; Tretinoin; Vascular Endothelial Growth Factor A | 2009 |
Peroxisome-proliferator receptor gamma represses hepatic sex hormone-binding globulin expression.
Topics: Anilides; Binding Sites; Cells, Cultured; Gene Expression Regulation; Humans; Liver; Mutant Proteins; PPAR alpha; PPAR delta; PPAR gamma; Promoter Regions, Genetic; Rosiglitazone; Sex Hormone-Binding Globulin; Thiazolidinediones; Tretinoin | 2009 |
Multiple myeloma cells undergo differentiation upon exposure to rosiglitazone and all-trans retinoic acid.
Topics: Aged; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Shape; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Immunoglobulin Light Chains; Integrin alpha5; Male; Middle Aged; Multiple Myeloma; PPAR gamma; Rosiglitazone; Syndecan-1; Thiazolidinediones; Tretinoin; Tumor Cells, Cultured | 2009 |
All-trans retinoic acid can intensify the growth inhibition and differentiation induction effect of rosiglitazone on multiple myeloma cells.
Topics: Aged; Apoptosis; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cell Survival; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Multiple Myeloma; PPAR gamma; Rosiglitazone; Thiazolidinediones; Tretinoin | 2009 |
Combined low doses of PPARgamma and RXR ligands trigger an intrinsic apoptotic pathway in human breast cancer cells.
Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Ligands; NF-kappa B; PPAR gamma; Retinoid X Receptors; Rosiglitazone; Thiazolidinediones; Tretinoin; Tumor Suppressor Protein p53 | 2009 |
[Rosiglitazone and all-trans retinoic acid inhibit human myeloma cell proliferation via apoptosis signaling pathway modulation].
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Multiple Myeloma; Rosiglitazone; Signal Transduction; Thiazolidinediones; Tretinoin | 2009 |
[Differentiating effect of PPARgamma ligand rosiglitazone and all trans-retinoic acid on myeloma cells and its possible mechanism].
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Drug Synergism; Humans; Integrin alpha5; Intracellular Signaling Peptides and Proteins; Multiple Myeloma; PPAR gamma; Rosiglitazone; Thiazolidinediones; Tretinoin; Up-Regulation | 2009 |
Bid as a potential target of apoptotic effects exerted by low doses of PPARγ and RXR ligands in breast cancer cells.
Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Ligands; Mitochondria; PPAR gamma; Retinoid X Receptors; RNA Interference; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; Tretinoin; Tumor Suppressor Protein p53; Up-Regulation | 2011 |
The influence of peroxisome proliferator-activated receptor γ(1) during differentiation of mouse embryonic stem cells to neural cells.
Topics: Anilides; Animals; Astrocytes; Cell Differentiation; Embryonic Stem Cells; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurogenesis; Neurons; PPAR gamma; Rosiglitazone; Thiazolidinediones; Tretinoin | 2012 |
Establishment of a cell-based drug screening model for identifying agonists of human peroxisome proliferator-activated receptor gamma (PPARγ).
Topics: Drug Evaluation, Preclinical; Flow Cytometry; Genes, Reporter; Genetic Vectors; HEK293 Cells; Humans; Luciferases; Models, Biological; PPAR gamma; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Rosiglitazone; Thiazolidinediones; Transfection; Tretinoin | 2012 |
[Influence of rosiglitazone and all-trans-retinoic acid on angiogenesis and growth of myeloma xenograft in nude mice].
Topics: Animals; Antigens, CD34; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microvessels; Multiple Myeloma; Neoplasm Transplantation; Neovascularization, Pathologic; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Tretinoin; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2012 |
Ligand Activity of Group 15 Compounds Possessing Triphenyl Substituent for the RXR and PPARγ Nuclear Receptors.
Topics: Alitretinoin; Arsenicals; Cell Line, Tumor; DNA; Genes, Reporter; Humans; Ligands; Luciferases, Renilla; Organometallic Compounds; Organophosphorus Compounds; PPAR gamma; Retinoid X Receptors; Rosiglitazone; Terphenyl Compounds; Thiazolidinediones; Transcription, Genetic; Tretinoin | 2016 |
All-trans retinoic acid shifts rosiglitazone-induced adipogenic differentiation to osteogenic differentiation in mouse embryonic fibroblasts.
Topics: Adipogenesis; Alkaline Phosphatase; Animals; Biomarkers; Bone Morphogenetic Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Embryonic Stem Cells; Female; Fibroblasts; Gene Expression Regulation, Developmental; Mice; Osteogenesis; PPAR gamma; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Signal Transduction; Smad Proteins; Thiazolidinediones; Tretinoin | 2016 |
Upregulation of transient receptor potential melastatin 6 channel expression by rosiglitazone and all-trans-retinoic acid in erlotinib-treated renal tubular epithelial cells.
Topics: Animals; Antineoplastic Agents; Cell Line; Epithelial Cells; Erlotinib Hydrochloride; Gene Expression Regulation; Humans; Hypoglycemic Agents; Kidney Tubules; MAP Kinase Signaling System; PPAR gamma; Protein Transport; Rats; Receptors, Retinoic Acid; Rosiglitazone; Tretinoin; TRPM Cation Channels; Up-Regulation | 2019 |
Activating PPARγ Increases NQO1 and γ-GCS Expression via Nrf2 in Thrombin-activated Microglia.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebral Hemorrhage; Disease Models, Animal; Female; Glutamate-Cysteine Ligase; Isothiocyanates; Male; Microglia; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; PPAR gamma; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sulfoxides; Thrombin; Tretinoin | 2020 |