Compounds > rosiglitazone
Page last updated: 2024-08-25

rosiglitazone and thiazolidines

rosiglitazone has been researched along with thiazolidines in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's10 (58.82)29.6817
2010's3 (17.65)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Akanuma, Y; Ide, T; Kadowaki, T; Mochizuki, T; Murakami, K; Ohashi, M; Tobe, K; Yazaki, Y1
Blanchard, SG; Cobb, JE; Collins, JL; Cooper, JP; Goreham, DM; Holmes, CP; Hull-Ryde, EA; Kliewer, SA; Lehmann, JM; Lenhard, JM; Milburn, MV; Miller, AB; Mohr, CP; Moore, LB; Oberfield, JL; Parks, DJ; Plunket, K; Willson, TM1
Chaput, E; Edgar, AD; Saladin, R; Silvestre, M1
Bolusu, G; Chakrabarti, R; Gershome, C; Hiriyan, J; Juluri, S; Kashireddy, P; Misra, P; Qi, C; Rajjak, A; Ramanujam, R; Rao, MS; Reddy, JK; Surapureddi, S; Vikramadithyan, RK; Yu, S; Zhu, YJ1
Narce, M; Poisson, JP1
Avery, MA; Benson, SC; Chittiboyina, A; Desai, P; Ho, CI; Kurtz, TW; Pershadsingh, HA; Pravenec, M; Qi, N; Wang, J1
Kaya, T; Sheu, SH; Vajda, S; Waxman, DJ1
Arch, JR; Augstein, P; Cawthorne, MA; Demuth, HU; Heinke, P; Hoffmann, T; Meyer, A; Sennitt, MV; Stocker, C; Subramanian, A; Wargent, E1
Brunskill, NJ; Chana, RS1
Dorais, M; LeLorier, J1
Blumberg, N; Francis, CW; Murant, TI; O'Brien, JJ; Phipps, RP; Pollock, SJ; Ray, DM; Spinelli, SL; Taubman, MB1
Bassett, K; Carleton, B; Carney, G; Dormuth, CR; Wright, JM1
Clark, J; Corinaldi, J; Hébert, RL; Jasmin, BJ; Miura, P; Nasrallah, R; Paris, G1
Beck-Nielsen, H; Home, PD; Jones, NP; Kahn, SE; Noronha, D; Viberti, G1
Haq, W; Katti, SB; Raza, S; Srivastava, AK; Srivastava, DS; Srivastava, SP1
Kaminskyy, D; Khyluk, D; Kryshchyshyn-Dylevych, A; Lesyk, R; Skóra, B; Szychowski, KA1
Bar, M; Holota, S; Khyluk, D; Lesyk, R; Roman, O; Skóra, B; Szychowski, KA; Tabęcka-Łonczyńska, A1

Trials

1 trial(s) available for rosiglitazone and thiazolidines

ArticleYear
Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials.
    Diabetologia, 2010, Volume: 53, Issue:9

    Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Neoplasms; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Thiazolidines; Treatment Outcome

2010

Other Studies

16 other study(ies) available for rosiglitazone and thiazolidines

ArticleYear
A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.
    Diabetes, 1998, Volume: 47, Issue:12

    Topics: Acyl-CoA Oxidase; Adipose Tissue; Animals; Blood Glucose; Body Weight; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Gene Expression; Hypoglycemic Agents; Insulin; Ligands; Lipid Metabolism; Liver; Male; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Obesity; Organ Size; Oxidoreductases; Radioligand Assay; Rats; Rats, Wistar; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Transcriptional Activation; Triglycerides

1998
A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, May-25, Volume: 96, Issue:11

    Topics: Adipocytes; Animals; Binding Sites; Cell Differentiation; Cell Line; Chlorocebus aethiops; Crystallography, X-Ray; Humans; Kinetics; Ligands; Mice; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Nuclear Proteins; Protein Structure, Secondary; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Transfection

1999
Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight.
    Biochemical and biophysical research communications, 2000, May-10, Volume: 271, Issue:2

    Topics: Acyl-CoA Oxidase; Animals; Apolipoprotein A-I; Apolipoprotein C-III; Apolipoproteins C; Body Weight; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Male; Mice; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Oxidoreductases; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Time Factors; Transcription Factors; Triglycerides

2000
PAT5A: a partial agonist of peroxisome proliferator-activated receptor gamma is a potent antidiabetic thiazolidinedione yet weakly adipogenic.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: 3T3 Cells; Adipocytes; Animals; Binding Sites; Carrier Proteins; Cyclic AMP Response Element-Binding Protein; Histone Acetyltransferases; Hypoglycemic Agents; Mediator Complex Subunit 1; Mice; Nuclear Receptor Coactivator 1; Pyridines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors

2003
Novel PPARgamma-dependent and independent effects for thiazolidinediones.
    Current opinion in lipidology, 2003, Volume: 14, Issue:6

    Topics: Animals; Bezafibrate; Body Weight; Chromans; Diabetes Mellitus, Type 2; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Proteins; Mice; Monocytes; Pancreas; Pioglitazone; PPAR alpha; PPAR gamma; Pregnancy Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Troglitazone; Tumor Necrosis Factor-alpha

2003
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Drug Evaluation, Preclinical; Gene Expression Regulation; Imidazoles; Insulin; Irbesartan; Losartan; Male; Mice; Models, Molecular; Myoblasts; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Structure-Activity Relationship; Telmisartan; Tetrazoles; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Triglycerides; Valine; Valsartan; Weight Gain

2004
Exploring the binding site structure of the PPAR gamma ligand-binding domain by computational solvent mapping.
    Biochemistry, 2005, Feb-01, Volume: 44, Issue:4

    Topics: Alkanesulfonates; Binding Sites; Cinnamates; Computational Biology; Humans; Ligands; Oxazines; Oxazoles; Phenylpropionates; PPAR gamma; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Rosiglitazone; Solvents; Thiazoles; Thiazolidinediones; Thiazolidines; Tyrosine

2005
Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone.
    Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Drinking; Drug Therapy, Combination; Drug Tolerance; Eating; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Obesity; Pentanoic Acids; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Time Factors

2005
Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma.
    American journal of nephrology, 2006, Volume: 26, Issue:1

    Topics: Albumins; Anilides; Animals; Cells, Cultured; Cholesterol; Chromans; Farnesol; Kidney Tubules, Proximal; Ligands; Mevalonic Acid; Opossums; Polyisoprenyl Phosphates; PPAR gamma; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Troglitazone

2006
Impact of the socioeconomic status on the probability of receiving formulary restricted thiazolidine (TZDs).
    The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2008,Winter, Volume: 15, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cohort Studies; Diabetes Mellitus, Type 2; Drug Prescriptions; Female; Formularies as Topic; Humans; Hypoglycemic Agents; Insurance, Health, Reimbursement; Insurance, Pharmaceutical Services; Male; Medical Records Systems, Computerized; Middle Aged; Pioglitazone; Quebec; Retrospective Studies; Risk Factors; Rosiglitazone; Socioeconomic Factors; Thiazolidinediones; Thiazolidines

2008
Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:1

    Topics: Adult; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Collagen; Dimerization; DNA; Female; Humans; Male; Megakaryocytes; Middle Aged; Monocytes; Peptide Fragments; Platelet Activation; PPAR gamma; Protein Binding; Protein Isoforms; Retinoid X Receptor alpha; Retinoid X Receptor beta; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Thiazolidines; Thrombin; Time Factors; Transport Vesicles

2008
Thiazolidinediones and fractures in men and women.
    Archives of internal medicine, 2009, Aug-10, Volume: 169, Issue:15

    Topics: Adult; Aged; British Columbia; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Disease Progression; Drug Therapy, Combination; Female; Fractures, Spontaneous; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Proportional Hazards Models; Prospective Studies; Risk; Rosiglitazone; Sex Factors; Sulfonylurea Compounds; Thiazolidinediones; Thiazolidines

2009
Thiazolidinediones alter growth and epithelial cell integrity, independent of PPAR-γ and MAPK activation, in mouse M1 cortical collecting duct cells.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:5

    Topics: Animals; Apoptosis; beta Catenin; Cadherins; Cell Proliferation; Chromans; Kidney Tubules, Collecting; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Models, Animal; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Rosiglitazone; Thiazolidinediones; Thiazolidines; Troglitazone

2010
Thiazolidin-4-one and thiazinan-4-one derivatives analogous to rosiglitazone as potential antihyperglycemic and antidyslipidemic agents.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: 3T3-L1 Cells; Animals; Blood Glucose; Cell Differentiation; Cell Line; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Dyslipidemias; Glucose; Hypoglycemic Agents; Hypolipidemic Agents; Male; Mice; Models, Chemical; Molecular Structure; Muscle, Skeletal; Rosiglitazone; Structure-Activity Relationship; Thiazines; Thiazolidinediones; Thiazolidines; Triglycerides

2013
4-thiazolidinone-based derivatives rosiglitazone and pioglitazone affect the expression of antioxidant enzymes in different human cell lines.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139

    Topics: A549 Cells; Antioxidants; Apoptosis; Caco-2 Cells; Caspase 3; Cell Line; Cell Line, Tumor; Humans; Neoplasms; Oxidative Stress; Pioglitazone; PPAR gamma; Reactive Oxygen Species; Rosiglitazone; Thiazolidines

2021
New 4-thiazolidinone-based molecules Les-2769 and Les-3266 as possible PPARγ modulators.
    Bioorganic chemistry, 2022, Volume: 128

    Topics: Antineoplastic Agents; Humans; Molecular Docking Simulation; PPAR gamma; Rosiglitazone; Thiazolidinediones; Thiazolidines

2022