Compounds > rosiglitazone

Page last updated: 2024-08-25

rosiglitazone and sirolimus

rosiglitazone has been researched along with sirolimus in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (26.67)	29.6817
2010's	10 (66.67)	24.3611
2020's	1 (6.67)	2.80

Authors

Authors	Studies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Eggo, MC; Holder, JC; Kumar, S; Patel, NG; Smith, SA	1
Andrade, L; da Silva, CA; de Bragança, AC; Fortes, MA; Giorgi, RR; Sanches, TR; Seguro, AC; Shimizu, MH	1
Acampado, E; Cheng, Q; Davis, T; Eppihimer, M; Ezell, T; Finn, AV; Gold, HK; John, M; Karmali, V; Kolodgie, FD; Lajoie, S; Nakazawa, G; Polavarapu, R; Raghunathan, C; Virmani, R; Xu, X	1
Cruz-Garcia, L; Gutiérrez, J; Navarro, I; Sánchez-Gurmaches, J	1
Cruzado, JM; Flaquer, M; Franquesa, M; Grinyó, JM; Herrero-Fresneda, I; Lloberas, N; Rosa, JL; Torras, J; Vidal, A	1
Cho, HJ; Choi, YE; Kim, BK; Kim, HS; Kwon, YW; Lee, HC; Lee, SW; Muller, DN; Park, JB; Park, KW; Yang, HM; Youn, SW	1
Bellmann, K; Blanchard, PG; Brûlé, S; Côté, M; Deshaies, Y; Festuccia, WT; Houde, VP; Marette, A; St-Pierre, P; Turcotte, V	1
Belchior, T; Blanchard, PG; Carpinelli, A; Chimin, P; Deshaies, Y; Festuccia, WT; Hirabara, SM; Magdalon, J; Marette, A; Paschoal, VA; Simões, D; St-Pierre, P	1
Fu, L; Gao, X; Li, H; Liu, C; Mei, C; Wang, X; Yang, M; Yuan, L	1
Barichello, T; Bogo, M; Burger, H; Constantino, L; Dal-Pizzol, F; de Quevedo, J; Dominguini, D; Gomes, LM; Kist, LW; Manfredini, A; Michels, M; Pinto, MC; Ritter, C; Silva, MC; Simioni, C; Singer, M; Steckert, A; Streck, E	1
Chen, G; Dong, YH; Du, ZY; Hu, J; Sun, YR; Tan, B; Wei, C; Xiao, X; Xie, R; Yu, J; Yuan, Q; Zhao, JL	1

Reviews

1 review(s) available for rosiglitazone and sirolimus

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

14 other study(ies) available for rosiglitazone and sirolimus

Article	Year
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation. Diabetes, 2003, Volume: 52, Issue:1 Topics: Adipocytes; Androstadienes; Cell Differentiation; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Leptin; Lipid Metabolism; Lipids; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Rosiglitazone; Signal Transduction; Sirolimus; Stem Cells; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha; Wortmannin	2003
Rosiglitazone prevents sirolimus-induced hypomagnesemia, hypokalemia, and downregulation of NKCC2 protein expression. American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:4 Topics: Animals; Aquaporin 2; Drug Interactions; Hypoglycemic Agents; Hypokalemia; Immunosuppressive Agents; Kidney; Kidney Function Tests; Magnesium; Male; Polyuria; Rats; Rats, Wistar; Rosiglitazone; Sirolimus; Sodium; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Thiazolidinediones; TRPM Cation Channels; Water	2009
Differential healing after sirolimus, paclitaxel, and bare metal stent placement in combination with peroxisome proliferator-activator receptor gamma agonists: requirement for mTOR/Akt2 in PPARgamma activation. Circulation research, 2009, Nov-06, Volume: 105, Issue:10 Topics: Animals; Aorta; Cells, Cultured; Drug-Eluting Stents; Endothelial Cells; Graft Occlusion, Vascular; Heme Oxygenase-1; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Models, Biological; Paclitaxel; PPAR gamma; Protein Kinases; Proto-Oncogene Proteins c-akt; Rabbits; Rosiglitazone; Sirolimus; Thiazolidinediones; TOR Serine-Threonine Kinases; Tubulin Modulators	2009
Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture. American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:2 Topics: Animals; Carbon Dioxide; Carnitine O-Palmitoyltransferase; Catecholamines; Cells, Cultured; Energy Metabolism; Epoxy Compounds; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Muscle Fibers, Skeletal; Oleic Acid; Oncorhynchus mykiss; Oxidation-Reduction; PPAR gamma; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rosiglitazone; Sirolimus; Thiazolidinediones; TOR Serine-Threonine Kinases; Triglycerides	2010
The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats. Life sciences, 2010, Jul-31, Volume: 87, Issue:5-6 Topics: Albuminuria; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Down-Regulation; Drug Synergism; Drug Therapy, Combination; Hypoglycemic Agents; Immunosuppressive Agents; Male; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sirolimus; Thiazolidinediones; Transcription Factors; Transforming Growth Factor beta1	2010
Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion. PloS one, 2011, Volume: 6, Issue:11 Topics: Animals; Catheterization; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Infusions, Intra-Arterial; Lipoproteins; Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; Muscle, Smooth, Vascular; Paclitaxel; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Sirolimus; Thiazolidinediones; Thromboplastin; Umbilical Arteries	2011
Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion. Journal of lipid research, 2012, Volume: 53, Issue:6 Topics: Adipose Tissue; Adiposity; Animals; Biological Transport; Drug Interactions; Fatty Acids; Gene Expression Regulation, Enzymologic; Hydrolysis; Lipid Metabolism; Lipoprotein Lipase; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Sirolimus; Thiazolidinediones; TOR Serine-Threonine Kinases; Triglycerides	2012
PPARγ activation attenuates glucose intolerance induced by mTOR inhibition with rapamycin in rats. American journal of physiology. Endocrinology and metabolism, 2014, May-01, Volume: 306, Issue:9 Topics: Animals; Cells, Cultured; Drug Antagonism; Glucose Intolerance; Insulin; Insulin-Secreting Cells; Male; Muscle, Skeletal; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sirolimus; Thiazolidinediones; TOR Serine-Threonine Kinases	2014
Concomitant use of rapamycin and rosiglitazone delays the progression of polycystic kidney disease in Han:SPRD rats: a study of the mechanism of action. American journal of physiology. Renal physiology, 2018, 05-01, Volume: 314, Issue:5 Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Epithelial Cells; Fibrosis; G1 Phase Cell Cycle Checkpoints; Humans; Kidney; Lipids; Male; Phosphorylation; Polycystic Kidney, Autosomal Dominant; PPAR gamma; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Renal Agents; Ribosomal Protein S6 Kinases, 70-kDa; Rosiglitazone; Signal Transduction; Sirolimus	2018
Mitochondrial dysfunction is associated with long-term cognitive impairment in an animal sepsis model. Clinical science (London, England : 1979), 2019, 09-30, Volume: 133, Issue:18 Topics: Animals; Autophagy; Brain; Cognitive Dysfunction; Disease Models, Animal; Male; Mitochondria; Mitochondrial Dynamics; Rats, Wistar; Rilmenidine; Rosiglitazone; Sepsis; Sirolimus; Survival Analysis; Up-Regulation	2019
Expression of TNF‑α and IL‑β can be suppressed via the PPAR‑γ/mTOR signaling pathway in BV‑2 microglia: A potential anti‑inflammation mechanism. Molecular medicine reports, 2020, Volume: 22, Issue:4 Topics: Anilides; Animals; Cell Line; Gene Expression Regulation; Interleukin-1beta; Lipopolysaccharides; Mice; Microglia; Phosphatidic Acids; Phosphorylation; PPAR gamma; Rosiglitazone; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha	2020