Compounds > rosiglitazone
Page last updated: 2024-08-25

rosiglitazone and prostaglandin d2

rosiglitazone has been researched along with prostaglandin d2 in 119 studies

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (9.24)18.2507
2000's82 (68.91)29.6817
2010's24 (20.17)24.3611
2020's2 (1.68)2.80

Authors

AuthorsStudies
Brun, RP; Chen, J; Evans, RM; Forman, BM; Spiegelman, BM; Tontonoz, P1
Kliewer, SA; Lehmann, JM; Lenhard, JM; Morris, DC; Patel, I; Willson, TM1
Adams, M; Chatterjee, VK; Digby, JE; Holder, JC; Lazar, MA; Montague, CT; O'Rahilly, S; Prins, JB; Sanders, L; Sewter, CP; Smith, SA1
Franciosa, MD; Greenberg, AS; Lien, P; Souza, SC; Yamamoto, MT1
Alvarez, JG; Evans, RM; Nagy, L; Thomazy, VA; Tontonoz, P1
Greenberg, AS; Rosenbaum, SE1
Gerritsen, ME; Kowalski, J; Xin, X; Yang, S1
Fleck, E; Goetze, S; Gotlibowski, T; Hsueh, WA; Kawano, H; Law, RE; Xi, XP1
Aaltonen, LA; de la Chapelle, A; Eng, C; Kum, JB; Mueller, E; Sarraf, P; Smith, WM; Spiegelman, BM; Wright, HM1
Burris, TP; Demarest, KT; Pelton, PD; Zhou, L1
Bailey, ST; Flanigan, A; Jiang, W; Keilbaugh, SA; Lazar, MA; Murthy, S; Rangwala, SM; Su, CG; Wen, X; Wu, GD1
Kalus, AM; Rubin, GL; Simpson, ER; Zhao, Y1
Anania, FA; Miyahara, T; Motomura, K; Rippe, R; Schrum, L; Tsukamoto, H; Willson, TM; Xiong, S; Yee, HF1
Angeli, V; Capron, M; Chinetti, G; Delerive, P; Faveeuw, C; Fontaine, J; Fougeray, S; Gosset, P; Maliszewski, C; Moser, M; Staels, B; Trottein, F1
Person, EC; Scanlan, TS; Taylor, RN; Waite, LL1
Bond, R; Cook, J; Gilkeson, G; Guyton, K; Halushka, P; Reilly, C1
Abe, I; Eto, K; Fujishima, M; Nakamura, Y; Ohya, Y1
Berry, E; Gilmour, R; Helliwell, R; Keelan, J; Marvin, K; Mitchell, M; Nijmeijer, B; Sato, T1
Cheung, HS; Di Battista, JA; Fahmi, H; Fernandes, JC; Martel-Pelletier, J; Pelletier, JP1
Dransfield, I; Farrow, SN; Haslett, C; Murray, J; Rossi, AG; Ward, C1
Frauwirth, KA; Lazar, MA; Rangwala, SM; Thompson, CB; Wang, YL1
Chatterjee, PK; Cuzzocrea, S; Hattori, Y; McDonald, MC; Mota-Filipe, H; Pisano, B; Thiemermann, C; Wayman, NS1
Chicheportiche, R; Dayer, JM; Dreyer, MG; Juge-Aubry, CE; Meier, CA1
Füzesi, L; Krüger, U; Middel, P; Mössner, R; Neumann, C; Reich, K; Schinner, S; Schulz, U1
Greenberg, AS; Mathys, JM; Rabbi, MF; Skolnik, PR1
Joe, EH; Jou, I; Park, EJ; Park, SY1
Armoni, M; Bar-Yoseph, F; Chen, H; Harel, C; Karnieli, E; Kritz, N; Quon, MJ1
Elstner, E; Fenner, MH; Liu, H; Possinger, K; Zang, C1
Delouis, C; Evain-Brion, D; Fournier, T; Hermouet, A; Pavan, L; Tarrade, A; Thérond, P; Titeux, M; Vidaud, M1
Burgermeister, E; Liscovitch, M; Tencer, L1
Greenberg, AS; Kang, YH; Muliro, KV; Palmer, HJ; Paulson, KE; Souza, SC; Yamamoto, MT1
Chao, VA; Pritts, EA; Sohn, SH; Taylor, RN; Waite, LL; Zhao, D1
Evers, BM; Farrow, B; Hashimoto, K; Iwamura, T; O'Connor, KL1
Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Di Rosa, M; Dugo, L; Genovese, T; Ianaro, A; Patel, NS; Pisano, B; Thiemermann, C1
Alemany, S; Caivano, M; Cohen, P; Rodriguez, C1
Brossart, P; Denzlinger, C; Grünebach, F; Lauber, K; Nencioni, A; Van Parijs, L; Wesselborg, S1
Boggi, U; Bugliani, M; Del Guerra, S; Del Prato, S; Lupi, R; Marchetti, P; Marselli, L; Mosca, F1
Kumar, AP; Piedrafita, FJ; Reynolds, WF1
Bonacci, JV; Gould, H; Harris, T; Stewart, AG; Ward, JE1
Bai, AH; Chan, FK; Chan, KK; Chan, MW; Chan, VY; Fu, YG; Leung, WK; Sung, JJ; To, KF; Wu, JR; Yu, J1
Akbiyik, F; Blumberg, N; Francis, CW; Gettings, KF; Phipps, RP; Ray, DM1
Koeffler, HP; Maira, G; Mangiola, A; Mastrangelo, R; Mirabella, M; Morosetti, R; Rutella, S; Servidei, T1
Atkins, KB; Brosius, FC; Northcott, CA; Watts, SW1
Andreeff, M; Chism, D; Collins, SJ; Elstner, E; Hu, W; Koeffler, HP; Konopleva, M; Kornblau, SM; McQueen, TJ; Schober, WD; Sudarikov, A; Tsao, T; Wang, RY; Younes, A1
Bängeroth, K; Elstner, E; Eucker, J; Heider, U; Jakob, C; Krebbel, H; Possinger, K; Sezer, O; Zang, C; Zavrski, I1
Chen, J; Chen, Q; Jiang, H; Shen, J; Shen, X; Sun, T1
Caputi, AP; Catalano, P; Crimi, N; Cuzzocrea, S; Di Paola, R; Genovese, T; Mastruzzo, C; Mazzon, E; Sortino, M; Thiemermann, C; Vancheri, C1
Burgess, HA; Daugherty, LE; Lakatos, HF; Phipps, RP; Ray, DM; Redonnet, M; Sime, PJ; Thatcher, TH1
Etoh, K; Fujieda, H; Hattori, Y; Imagawa, M; Kohda, K; Miyata, N; Nakagawa, H; Nishizuka, M; Suzuki, T; Usui, S1
Bianchi, A; Boyault, S; Francois, M; Jouzeau, JY; Koufany, M; Moulin, D; Netter, P; Sebillaud, S; Terlain, B1
Ackerman, WE; Kniss, DA; Rovin, BH; Zhang, XL1
Allred, CD; Kilgore, MW1
Artwohl, M; Baumgartner-Parzer, SM; Freudenthaler, A; Fürnsinn, C; Hölzenbein, T; Huttary, N; Waldhäusl, WK1
Hart, CM; Mazzella, LJ; Polikandriotis, JA; Rupnow, HL1
Boscá, L; Cárdenas, A; Castillo, J; Dávalos, A; Hurtado, O; Lizasoain, I; Lorenzo, P; Moro, MA; Pereira, MP; Serena, J; Vivancos, J1
Amiri, F; Benkirane, K; Diep, QN; El Mabrouk, M; Schiffrin, EL1
Bai, X; Chen, WC; Lin, MS1
Becchi, M; Boutin, JA; Cozzone, D; D'Orazio, D; Ferry, G; Géloën, A; Guichardant, M; Lagarde, M; Nosjean, O; Soares, AF1
Bissonnette, RP; Cesario, RM; Lamph, WW; Stone, J; Yen, WC1
Bianchi, A; Galteau, MM; Jouzeau, JY; Koufany, M; Moulin, D; Netter, P; Sebillaud, S; Terlain, B1
Chen, JJ; Cheung, WM; Lin, H; Lin, TN; Liou, JY; Shyue, SK; Wu, JS; Wu, KK1
Coyle, AT; Kinsella, BT1
Cuzzocrea, S1
Jang, KY; Jang, YB; Kang, KP; Kim, DH; Kim, W; Lee, JE; Lee, S; Moon, SO; Park, SK; Sung, MJ1
Hiramatsu, Y; Masumoto, A; Masuyama, H; Suwaki, N; Takamoto, N1
Horinaka, M; Kouhara, J; Nakata, S; Sakai, T; Shiraishi, T; Wakada, M; Yoshida, T1
Chen, K; Ding, H; Jiang, H; Luo, H; Shen, X; Sun, T; Ye, F1
Elstner, E; Eucker, J; Heider, U; Jakob, C; Kaiser, M; Krebbel, H; Sezer, O; Sterz, J; Zang, C; Zavrski, I1
Blero, D; Bruyns, C; Caspers, L; De Graef, C; Driessens, G; Dulku, S; Gonzalez, NS; Willermain, F1
Caso, JR; García-Bueno, B; Leza, JC; Lorenzo, P; Pérez-Nievas, BG1
Fernández, PL1
Chadburn, A; Csernus, B; Hyjek, E; Jo, SH; Liu, Y; Wang, YL; Yang, C1
Evain-Brion, D; Fournier, T; Handschuh, K; Tsatsaris, V1
Authier, H; Auwerx, J; Balard, P; Benoit-Vical, F; Berry, A; Chambon, P; Coste, A; Desvergne, B; Lagane, C; Lepert, JC; Magnaval, JF; Metzger, D; Olagnier, D; Pipy, B; Séguéla, JP; Wahli, W1
Barrera, G; Briatore, F; Cerbone, A; Dianzani, MU; Ferretti, C; Laurora, S; Pizzimenti, S; Toaldo, C1
Alou, L; Caso, JR; Colón, A; Cos, E; Gómez-Lus, ML; Leza, JC; Lizasoain, I; Lorenzo, P; Menchén, L; Menchén, P; Moro, MA; Ponferrada, A; Sevillano, D1
Bai, X; Chen, WC; Lin, MS; Wang, YD1
Fu, WM; Lin, CP; Lin, TH; Tang, CH; Yang, RS1
Blay, J; Lowthers, EL; Richard, CL1
Flier, JS; Gardner, NP; Guan, HP; Kershaw, EE; Lazar, MA; Schupp, M1
Caito, S; Edirisinghe, I; Kode, A; Phipps, RP; Rahman, I; Rajendrasozhan, S; Yang, SR1
Jang, SK; Kim, JH; Kim, WJ1
Blanchard, J; Eismann, T; Galloway, E; Huber, N; Kuboki, S; Lentsch, AB; Schuster, R; Shin, T; Zingarelli, B1
Gao, DF; Hao, GH; Niu, XL; Wang, NP; Wei, J1
Baek, SJ; Cekanova, M; Kim, K; Li, X; Yuan, JS1
Abdel-Aleem, OS; Churi, SB; Scuderi-Porter, H; Taylor, BK; Tumber, KK1
Aeed, H; Bruck, R; Halpern, Z; Pines, M; Weiss, S; Zvibel, I1
Dong, YW; Wang, XP; Wu, K1
Cerny, L; Rehan, VK; Sakurai, R; Santos, J; Shin, E; Torday, JS; Wang, Y1
Ferguson, HE; Garcia-Bates, TM; Huxlin, KR; Kulkarni, A; Lehmann, GM; Phipps, RP; Sime, PJ; Thatcher, TH1
Beguin, Y; de Seny, D; Desoroux, A; Malaise, MG; Relic, B; Zeddou, M1
Baglole, CJ; Ferguson, HE; Garcia-Bates, TM; Kottmann, RM; Olsen, KC; Phipps, RP; Sime, PJ; Strong, ER; Thatcher, TH1
Li, H; Pauza, CD1
Abdel-Aleem, OS; Badr, MZ; Donahue, RR; McNamara, KC; Morgenweck, J; Taylor, BK1
Barrera, G; Cerbone, A; Daniela, B; Dianzani, MU; Ferretti, C; Giglioni, B; Menegatti, E; Minelli, R; Pettazzoni, P; Pizzimenti, S; Toaldo, C1
Goren, NB; Hovsepian, E; Penas, F1
Garzón, B; Pérez-Sala, D; Zorrilla, S1
Atherton, RE; Gibbins, JM; Jones, CI; Kaiser, WJ; Moraes, LA; Sage, T; Spyridon, M1
Choi, GS; Jou, I; Kim, SH; Park, HS; Park, SM; Ye, YM1
Dhaliwal, LK; Dhawan, V; Saha, SC; Sharma, I1
Armani, C; Bardelli, C; Breschi, MC; Brunelleschi, S; Carmazzi, Y; Celi, A; Cordazzo, C; Neri, T; Paggiaro, P; Pegoli, A1
Chen, C; Chen, X; Du, H; Zhang, J1
Amoruso, A; Balbo, P; Bardelli, C; Brunelleschi, S; Celi, A; Federici Canova, D; Fresu, L; Neri, T1
Alves, CF; Carregaro, V; Cheraim, AB; Cunha, FQ; da Silva, CA; de Oliveira, JR; Farnesi-de-Assunção, TS; Napimoga, MH1
Chen, XF; Dong, L; Lin, J; Wan, CJ1
Li, J; Liu, L; Liu, Y; Sun, J; Xia, S; Xu, D; Xu, Y; Yang, Z; Zhang, L; Zou, F1
Choi, YJ; Ham, SA; Hwang, JS; Kang, ES; Kang, KR; Kim, GH; Lee, JH; Lee, WJ; Paek, KS; Park, MH; Seo, HG; Yoo, T1
Bogacka, I; Bogacki, M; Chojnowska, K; Kurzyńska, A2
Hindman, HB; Huxlin, KR; Jeon, KI; Kulkarni, A; Phipps, RP; Sime, PJ; Woeller, CF1
Casali, CI; Faggionato, D; Gómez, EM; Tome, MC; Weber, K1
Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I1
Dong, X; Gao, D; Hao, G; Liu, Z; Meng, Z; Ning, N; Niu, X; Yang, G1
Ennis, WJ; Fang, MM; Koh, TJ; Mirza, RE; Novak, ML; Sui, A; Urao, N1
Huxlin, KR; Jeon, KI; Phipps, RP; Sime, PJ2
Bai, M; Chen, Y; Ding, G; Huang, S; Jia, Z; Xu, Y; Zhang, A; Zhang, Y; Zhao, M1
Chen, Y; Duan, Y; Guo, F; Hajjar, DP; Han, J; Hu, H; Hu, W; Kong, D; Li, Q; Li, X; Ma, C; Miao, QR; Wang, H; Wei, Z; Yang, X; Yu, M; Zhang, S; Zhang, Y; Zhu, Y1
Feng, J; Gao, X; Li, J; Li, W; Li, Z; Lu, M; Meng, P; Zhang, Y1

Reviews

1 review(s) available for rosiglitazone and prostaglandin d2

ArticleYear
Peroxisome proliferator-activated receptors and acute lung injury.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Humans; Ligands; PPAR alpha; PPAR gamma; Prostaglandin D2; Respiratory Distress Syndrome; Rosiglitazone; Thiazolidinediones

2006

Other Studies

118 other study(ies) available for rosiglitazone and prostaglandin d2

ArticleYear
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma.
    Cell, 1995, Dec-01, Volume: 83, Issue:5

    Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Carrier Proteins; Cell Differentiation; Complement Factor D; DNA-Binding Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fibroblasts; Hypoglycemic Agents; Ligands; Mice; Molecular Sequence Data; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Pioglitazone; Prostaglandin D2; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Serine Endopeptidases; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation

1995
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.
    Cell, 1995, Dec-01, Volume: 83, Issue:5

    Topics: Adipocytes; Animals; Binding, Competitive; Cell Differentiation; Cells, Cultured; Fibroblasts; Hypoglycemic Agents; Ligands; Mice; Microbodies; Prostaglandin D2; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation

1995
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.
    The Journal of clinical investigation, 1997, Dec-15, Volume: 100, Issue:12

    Topics: Adipocytes; Animals; Cell Differentiation; Cells, Cultured; Chromans; Humans; Mice; Microbodies; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Stem Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Troglitazone

1997
BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones.
    Diabetes, 1998, Volume: 47, Issue:4

    Topics: 3T3 Cells; Adipocytes; Animals; Carrier Proteins; Fatty Acids, Nonesterified; Glycerol; Hypoglycemic Agents; Insulin Resistance; Lipolysis; Mice; Perilipin-1; Phosphoproteins; Prostaglandin D2; Rosiglitazone; Sterol Esterase; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha

1998
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL.
    Cell, 1998, Apr-17, Volume: 93, Issue:2

    Topics: Alitretinoin; Animals; Arteriosclerosis; CD36 Antigens; Cell Differentiation; Dimerization; Foam Cells; HL-60 Cells; Humans; Ligands; Lipoproteins, LDL; Macrophages; Membrane Proteins; Mice; Mice, Transgenic; Monocytes; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Retinoic Acid; Receptors, Scavenger; Retinoid X Receptors; Rosiglitazone; Scavenger Receptors, Class B; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Tretinoin

1998
The short- and long-term effects of tumor necrosis factor-alpha and BRL 49653 on peroxisome proliferator-activated receptor (PPAR)gamma2 gene expression and other adipocyte genes.
    Molecular endocrinology (Baltimore, Md.), 1998, Volume: 12, Issue:8

    Topics: Adipocytes; Animals; Carrier Proteins; Cell Differentiation; Down-Regulation; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Gene Expression Regulation; Hypoglycemic Agents; Mice; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Perilipin-1; Phosphoproteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Sterol Esterase; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha

1998
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo.
    The Journal of biological chemistry, 1999, Mar-26, Volume: 274, Issue:13

    Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Cornea; Eicosanoids; Endothelium, Vascular; Gene Expression Regulation; Humans; Ligands; Neovascularization, Physiologic; Prostaglandin D2; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

1999
PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:5

    Topics: Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cells, Cultured; Chemotactic Factors; Chromans; Cycloheximide; Dactinomycin; Enzyme Activation; Insulin-Like Growth Factor I; Ligands; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandin D2; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thrombin; Transcription Factors; Troglitazone

1999
Loss-of-function mutations in PPAR gamma associated with human colon cancer.
    Molecular cell, 1999, Volume: 3, Issue:6

    Topics: Amino Acid Substitution; Binding Sites; Chromans; Colorectal Neoplasms; Dimerization; DNA-Binding Proteins; Exons; Genes, Tumor Suppressor; Humans; Hydroxyeicosatetraenoic Acids; Ligands; Linoleic Acids; Linoleic Acids, Conjugated; Mutation; Prostaglandin D2; Protein Binding; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Troglitazone

1999
PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes.
    Biochemical and biophysical research communications, 1999, Aug-02, Volume: 261, Issue:2

    Topics: Adipocytes; Carrier Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Chromans; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Gene Expression; Humans; Kinetics; Monocytes; Myelin P2 Protein; Neoplasm Proteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Suppressor Proteins

1999
A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:4

    Topics: Animals; Caco-2 Cells; Colitis; Cytokines; DNA-Binding Proteins; Epithelium; Gene Expression; HT29 Cells; Humans; I-kappa B Proteins; Inflammation; Inflammatory Bowel Diseases; Interleukin-8; Ligands; Mice; Microbodies; NF-kappa B; NF-KappaB Inhibitor alpha; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

1999
Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: possible implications for breast cancer therapy.
    Cancer research, 2000, Mar-15, Volume: 60, Issue:6

    Topics: Adipose Tissue; Animals; Aromatase; Aromatase Inhibitors; Binding, Competitive; Breast; Breast Neoplasms; Cell Line; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Estrogens; Female; Gene Expression Regulation, Enzymologic; Humans; Ligands; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone

2000
Peroxisome proliferator-activated receptors and hepatic stellate cell activation.
    The Journal of biological chemistry, 2000, Nov-17, Volume: 275, Issue:46

    Topics: Animals; Cell Size; Cell Survival; Cells, Cultured; Collagen; DNA; Gene Expression Regulation; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Promoter Regions, Genetic; Prostaglandin D2; Protein Binding; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha

2000
Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells.
    FEBS letters, 2000, Dec-15, Volume: 486, Issue:3

    Topics: Animals; Antigens, CD; CD40 Antigens; Cell Differentiation; Dendritic Cells; Dimethyl Sulfoxide; Interferon-gamma; Interleukin-12; Interleukins; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors

2000
Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12-14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo.
    Endocrinology, 2001, Volume: 142, Issue:2

    Topics: Hot Temperature; Immunologic Factors; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Serum Albumin; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured

2001
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
    Journal of leukocyte biology, 2001, Volume: 69, Issue:4

    Topics: Animals; Cyclopentanes; DNA-Binding Proteins; Enzyme Activation; Epoprostenol; I-kappa B Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Prostaglandin D2; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Thromboxane B2; Transcription Factors; Tumor Necrosis Factor-alpha

2001
Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle.
    European journal of pharmacology, 2001, Jun-29, Volume: 423, Issue:1

    Topics: Analysis of Variance; Animals; Barium; Calcium; Chromans; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Humans; Insulin Resistance; Ion Channels; Isoxazoles; Membrane Potentials; Muscle, Smooth, Vascular; Pioglitazone; Potassium Channels; Prostaglandin D2; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone

2001
15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells.
    Prostaglandins & other lipid mediators, 2001, Volume: 66, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Amnion; Apoptosis; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Enzyme Activation; Humans; Hypoglycemic Agents; Immunologic Factors; Ligands; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors

2001
Peroxisome proliferator-activated receptor gamma activators inhibit MMP-1 production in human synovial fibroblasts likely by reducing the binding of the activator protein 1.
    Osteoarthritis and cartilage, 2002, Volume: 10, Issue:2

    Topics: Aged; Blotting, Northern; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Expression; Humans; Interleukin-1; Matrix Metalloproteinase 1; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Synovial Membrane; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic

2002
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Jun-15, Volume: 168, Issue:12

    Topics: Apoptosis; Binding Sites; Caspases; Cell Death; Cells, Cultured; Dinoprost; DNA-Binding Proteins; Enzyme Activation; Eosinophils; Granulocytes; Humans; Hydrolysis; I-kappa B Proteins; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Peroxisomes; Prostaglandin D2; Protein Biosynthesis; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Prostaglandin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2002
Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.
    The Journal of biological chemistry, 2002, Aug-30, Volume: 277, Issue:35

    Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Humans; Hypoglycemic Agents; Interleukin-3; Lymphocyte Activation; Membrane Potentials; Mice; Mice, Inbred C57BL; Mitochondria; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Rosiglitazone; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Up-Regulation

2002
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:9

    Topics: Adult; Animals; Cardiotonic Agents; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chemokine CCL2; Clofibrate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ligands; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Pioglitazone; Prostaglandin D2; Prostaglandins A; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2002
Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma.
    Cytokine, 2002, Jun-21, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Line; Cell Separation; Enzyme Inhibitors; Fibrinolytic Agents; Flow Cytometry; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Ligands; Monocytes; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Sialoglycoproteins; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Tretinoin; Tumor Necrosis Factor-alpha; Up-Regulation; Vitamin D

2002
Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma.
    The Journal of investigative dermatology, 2002, Volume: 119, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Chromans; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gene Expression Regulation, Neoplastic; Humans; Immunologic Factors; Melanoma; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Skin Neoplasms; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured

2002
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects.
    Journal of acquired immune deficiency syndromes (1999), 2002, Sep-01, Volume: 31, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Chromans; Fenofibrate; HIV-1; Humans; Leukocytes, Mononuclear; Macrophages, Alveolar; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Necrosis Factor-alpha; Virus Replication

2002
15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia.
    The Journal of biological chemistry, 2003, Apr-25, Volume: 278, Issue:17

    Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Carrier Proteins; DNA-Binding Proteins; Gene Expression Regulation; Inflammation; Janus Kinase 1; Janus Kinase 2; Neuroglia; Phosphorylation; Prostaglandin D2; Protein Biosynthesis; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Rosiglitazone; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors

2003
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect.
    The Journal of biological chemistry, 2003, Aug-15, Volume: 278, Issue:33

    Topics: Adipocytes; Animals; CHO Cells; Cricetinae; Dimerization; Fibroblasts; Gene Expression Regulation; Genetic Complementation Test; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Immunologic Factors; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Promoter Regions, Genetic; Prostaglandin D2; Protein Structure, Tertiary; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Suppression, Genetic; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic

2003
PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro.
    Breast cancer research and treatment, 2003, Volume: 79, Issue:1

    Topics: Breast Neoplasms; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nuclear Proteins; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Tissue Inhibitor of Metalloproteinases; Transcription Factors; Tretinoin; Tumor Cells, Cultured

2003
Human invasive trophoblasts transformed with simian virus 40 provide a new tool to study the role of PPARgamma in cell invasion process.
    Carcinogenesis, 2003, Volume: 24, Issue:8

    Topics: Antigens, Polyomavirus Transforming; Cell Division; Cell Transformation, Viral; Cells, Cultured; DNA Primers; Dose-Response Relationship, Drug; Humans; Immunoblotting; Nuclear Proteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Simian virus 40; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Trophoblasts

2003
Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.
    Oncogene, 2003, Jun-19, Volume: 22, Issue:25

    Topics: Adenocarcinoma; Antigens, Differentiation; Antigens, Neoplasm; Breast Neoplasms; Caveolin 1; Caveolin 2; Caveolins; Cell Differentiation; Cell Line; Chromans; Colonic Neoplasms; Dimerization; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Kidney; Ligands; Macromolecular Substances; Membrane Microdomains; Neoplasm Proteins; Phenotype; Phenylacetates; Prostaglandin D2; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; RNA, Neoplasm; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Tumor Cells, Cultured

2003
TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes.
    Journal of cellular biochemistry, 2003, Aug-15, Volume: 89, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Blotting, Western; Butadienes; Carrier Proteins; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; JNK Mitogen-Activated Protein Kinases; Lipolysis; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Perilipin-1; Phosphoproteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha

2003
Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element.
    Fertility and sterility, 2003, Volume: 80, Issue:2

    Topics: Base Sequence; Cells, Cultured; Chemokine CCL5; Endometriosis; Female; Humans; Ligands; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Response Elements; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection

2003
Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator.
    Surgery, 2003, Volume: 134, Issue:2

    Topics: Chromans; Humans; Integrins; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Pancreatic Neoplasms; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Tissue Plasminogen Activator; Transcription Factors; Troglitazone; Tumor Cells, Cultured

2003
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Animals; Benzhydryl Compounds; Blood Pressure; Epoxy Compounds; Immunologic Factors; Intercellular Adhesion Molecule-1; Interleukin-1; Intestinal Mucosa; Intestines; Ligands; Male; Malondialdehyde; Peroxidase; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Reperfusion Injury; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine; Vasodilator Agents

2003
15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinogens; Cell Division; Cell Line; Enzyme Activation; Enzyme Inhibitors; Fibrinolytic Agents; Gene Expression Regulation, Enzymologic; Indoles; Ligands; Lipopolysaccharides; Macrophages; Maleimides; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Precipitin Tests; Prostaglandin D2; Protein Isoforms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; RNA, Messenger; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazolidinediones; Time Factors

2003
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Nov-15, Volume: 171, Issue:10

    Topics: Apoptosis; Cyclopentanes; Down-Regulation; Growth Inhibitors; Humans; Intracellular Membranes; Jurkat Cells; Lymphocyte Activation; Membrane Potentials; Mitochondria; Oxidative Stress; Permeability; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Rosiglitazone; Signal Transduction; T-Lymphocyte Subsets; Thiazolidinediones; Transcription Factors

2003
Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 286, Issue:4

    Topics: Adipose Tissue; Adult; Aged; Blood Glucose; Fatty Acids; Fatty Acids, Nonesterified; Female; Glucose; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Pancreas; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription Factors; Triglycerides

2004
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism.
    The Journal of biological chemistry, 2004, Feb-27, Volume: 279, Issue:9

    Topics: Alu Elements; Animals; Arteriosclerosis; Binding Sites; Bone Marrow Cells; Cells, Cultured; Estradiol; Estrogen Receptor alpha; Estrogens; Gene Expression Regulation, Enzymologic; Genotype; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Peroxidase; Polymorphism, Genetic; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, LDL; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription Factors

2004
PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms.
    British journal of pharmacology, 2004, Volume: 141, Issue:3

    Topics: Bronchi; Cell Count; Cell Division; Cells, Cultured; Humans; Ligands; Muscle, Smooth; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors

2004
Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells.
    Gut, 2004, Volume: 53, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cyclooxygenase 2; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Ligands; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Nuclear Receptor Coactivators; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rosiglitazone; Stomach Neoplasms; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured

2004
Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes.
    Blood, 2004, Sep-01, Volume: 104, Issue:5

    Topics: Adenosine Triphosphate; Blood Platelets; Bone Marrow Cells; CD40 Ligand; Cell Line; DNA-Binding Proteins; Gene Expression; Humans; Hypoglycemic Agents; Megakaryocytes; Platelet Aggregation; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Thromboxane B2; Transcription Factors

2004
The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines.
    International journal of oncology, 2004, Volume: 25, Issue:2

    Topics: Apoptosis; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cyclooxygenase 2; G2 Phase; Gene Expression; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Isoenzymes; Membrane Proteins; Neurofilament Proteins; PPAR gamma; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rosiglitazone; Thiazolidinediones; Tumor Cells, Cultured; Up-Regulation; Vimentin

2004
Effects of PPAR-gamma ligands on vascular smooth muscle marker expression in hypertensive and normal arteries.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:1

    Topics: Animals; Aorta; Arteries; Biomarkers; Blood Pressure; Carotid Arteries; Chromans; Deoxyglucose; Desoxycorticosterone; Glucose Transporter Type 4; Hypertension; Ligands; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Smooth, Vascular; PPAR gamma; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sodium Chloride; Thiazolidinediones; Troglitazone

2005
Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:10

    Topics: Agar; Apoptosis; Blotting, Western; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Dimerization; Fibrinolytic Agents; Flow Cytometry; HL-60 Cells; Humans; Imidazoles; Immunologic Factors; Jurkat Cells; Leukemia; Ligands; Oleanolic Acid; Phagocytosis; Plasmids; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Transcriptional Activation; Transfection; U937 Cells

2004
Ligands of peroxisome proliferator-activated receptor gamma induce apoptosis in multiple myeloma.
    Anti-cancer drugs, 2004, Volume: 15, Issue:10

    Topics: Apoptosis; Bone Marrow Cells; Cell Line, Tumor; Cell Proliferation; Humans; Ligands; Multiple Myeloma; Pioglitazone; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones

2004
A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.
    Analytical biochemistry, 2004, Dec-15, Volume: 335, Issue:2

    Topics: alpha-Galactosidase; Anilides; Cells, Cultured; Chromans; CREB-Binding Protein; Drug Evaluation, Preclinical; Genes, Reporter; Indomethacin; Ligands; Nuclear Proteins; Oxazoles; Pioglitazone; PPAR gamma; Prostaglandin D2; Protein Binding; Rosiglitazone; Thiazolidinediones; Trans-Activators; Troglitazone; Two-Hybrid System Techniques; Tyrosine; Yeasts

2004
Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury.
    The European respiratory journal, 2005, Volume: 25, Issue:2

    Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Biopsy; Bleomycin; Epoxy Compounds; Immunoenzyme Techniques; Instillation, Drug; Male; Mice; Nitric Oxide Synthase; Peroxidase; Poly(ADP-ribose) Polymerases; Prostaglandin D2; Pulmonary Fibrosis; Random Allocation; Rosiglitazone; Thiazolidinediones; Tyrosine; Weight Loss

2005
PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:6

    Topics: Actins; Anilides; Cell Differentiation; Collagen Type I; Fibroblasts; Humans; Hypoglycemic Agents; Lung; Muscle, Smooth; PPAR gamma; Prostaglandin D2; Pulmonary Fibrosis; Rosiglitazone; Thiazolidinediones; Transforming Growth Factor beta

2005
Design, synthesis, and biological activity of novel PPARgamma ligands based on rosiglitazone and 15d-PGJ2.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: Adipocytes; Animals; Cells, Cultured; Drug Design; Ligands; Models, Molecular; Molecular Structure; PPAR gamma; Prostaglandin D2; Protein Binding; Rats; Rosiglitazone; Thiazolidinediones

2005
Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:3

    Topics: Animals; Cell Culture Techniques; Fibroblasts; Immunologic Factors; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Knee Joint; Male; Models, Animal; Peroxisome Proliferator-Activated Receptors; PPAR delta; PPAR gamma; PPAR-beta; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Interleukin-1; Rosiglitazone; Sialoglycoproteins; Synovial Membrane; Thiazolidinediones

2005
Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells.
    Biology of reproduction, 2005, Volume: 73, Issue:3

    Topics: Amnion; Cells, Cultured; Chromans; Cyclooxygenase 2; Epithelial Cells; Gene Expression Regulation; Humans; Membrane Proteins; NF-kappa B; PPAR gamma; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha

2005
Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.
    Molecular and cellular endocrinology, 2005, May-12, Volume: 235, Issue:1-2

    Topics: Alitretinoin; Anilides; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; HT29 Cells; Humans; Ligands; Lung Neoplasms; PPAR gamma; Prostaglandin D2; Retinoid X Receptor alpha; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transfection; Tretinoin

2005
Thiazolidinediones inhibit apoptosis and heat shock protein 60 expression in human vascular endothelial cells.
    Thrombosis and haemostasis, 2005, Volume: 93, Issue:5

    Topics: Aorta; Apoptosis; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Chaperonin 60; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Endothelium, Vascular; Enzyme Activation; Humans; Hypoglycemic Agents; Ligands; Microscopy, Phase-Contrast; Mitochondria; Pioglitazone; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Rosiglitazone; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tumor Necrosis Factor-alpha; von Willebrand Factor

2005
Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:9

    Topics: Anilides; Cells, Cultured; Endothelium, Vascular; Genes, Reporter; Humans; Hypoglycemic Agents; Ligands; Nitric Oxide; PPAR gamma; Prostaglandin D2; RNA, Small Interfering; Rosiglitazone; Signal Transduction; Thiazolidinediones; Umbilical Veins

2005
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Disease Models, Animal; Drug Administration Schedule; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; NF-kappa B; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oligonucleotide Array Sequence Analysis; PPAR gamma; Prostaglandin D2; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Time Factors

2006
PPAR-gamma inhibits ANG II-induced cell growth via SHIP2 and 4E-BP1.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Carrier Proteins; Cell Proliferation; Intracellular Signaling Peptides and Proteins; Leucine; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoproteins; Phosphoric Monoester Hydrolases; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Rosiglitazone; Signal Transduction; Thiazolidinediones; Thymidine

2006
Induction of apoptosis in colorectal cancer cells by peroxisome proliferators-activated receptor gamma activation up-regulating PTEN and inhibiting PI3K activity.
    Chinese medical journal, 2005, Sep-05, Volume: 118, Issue:17

    Topics: Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; HT29 Cells; Humans; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; PPAR gamma; Prostaglandin D2; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rosiglitazone; Thiazolidinediones; Tumor Suppressor Proteins; Up-Regulation

2005
Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma.
    Biochemical and biophysical research communications, 2005, Nov-18, Volume: 337, Issue:2

    Topics: Adipocytes; Hypoglycemic Agents; Ligands; PPAR gamma; Prostaglandin D2; Protein Binding; Rosiglitazone; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazolidinediones; Time Factors

2005
Differentiation and growth inhibition mediated via the RXR:PPARgamma heterodimer in colon cancer.
    Cancer letters, 2006, Aug-28, Volume: 240, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Bexarotene; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Fibrinolytic Agents; Humans; Male; Membrane Proteins; Mice; Mice, Nude; PPAR gamma; Prostaglandin D2; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazolidinediones; Transplantation, Heterologous; Tumor Cells, Cultured

2006
Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostagl
    Arthritis research & therapy, 2005, Volume: 7, Issue:6

    Topics: Animals; Cell Membrane; Cell Survival; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Drug Combinations; Gene Expression; Immunologic Factors; Interleukin-1; Intramolecular Oxidoreductases; Male; PPAR gamma; Prostaglandin D2; Prostaglandin-E Synthases; Rats; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transfection

2005
15d-prostaglandin J2 protects brain from ischemia-reperfusion injury.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:3

    Topics: Adenoviridae; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cyclooxygenase 1; Gene Transfer Techniques; Genetic Therapy; Heme Oxygenase-1; Infarction, Middle Cerebral Artery; Male; Necrosis; Neurons; Neuroprotective Agents; PPAR gamma; Prostaglandin D2; Rats; Rats, Long-Evans; Reperfusion Injury; Rosiglitazone; Thiazolidinediones; Vasodilator Agents

2006
Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells.
    Biochemical pharmacology, 2006, Apr-28, Volume: 71, Issue:9

    Topics: Cell Line; Cell Line, Tumor; Chromans; Genes, Reporter; Humans; Leukemia, Erythroblastic, Acute; Luciferases; PPAR gamma; Promoter Regions, Genetic; Prostaglandin D2; Protein Isoforms; Receptors, Thromboxane A2, Prostaglandin H2; Retinoid X Receptor alpha; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription Factor AP-1; Transcription, Genetic; Troglitazone

2006
Rosiglitazone ameliorates cisplatin-induced renal injury in mice.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8

    Topics: Anilides; Animals; Apoptosis; C-Peptide; Cell Line; Chromans; Cisplatin; Drug Evaluation, Preclinical; Glioma; Humans; Hypoglycemic Agents; Inflammation; Insulin; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Tubules, Proximal; Macrophages; Male; Mice; Mice, Inbred C57BL; Monocytes; PPAR gamma; Prostaglandin D2; Protein Transport; Rosiglitazone; Thiazolidinediones; Transcription Factor RelA; Troglitazone; Tumor Necrosis Factor-alpha

2006
Expression and potential role of peroxisome proliferator-activated receptor gamma in the placenta of diabetic pregnancy.
    Placenta, 2007, Volume: 28, Issue:4

    Topics: Animals; Blood Glucose; Cell Line, Tumor; Cell Proliferation; Choriocarcinoma; Chorionic Gonadotropin; Diabetes Mellitus, Experimental; Female; Fibrinolytic Agents; Humans; Immunologic Factors; Mice; Mice, Inbred ICR; Placenta; PPAR gamma; Pregnancy; Pregnancy in Diabetics; Prostaglandin D2; Rosiglitazone; Thiazolidinediones; Trophoblasts; Vascular Endothelial Growth Factor A

2007
15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Gene Expression; Humans; Jurkat Cells; Membrane Glycoproteins; Neoplasms; Pioglitazone; PPAR gamma; Prostaglandin D2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA Stability; RNA, Messenger; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2006
Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2006, Volume: 18, Issue:1-3

    Topics: Anilides; Animals; Biological Transport; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Microscopy, Fluorescence; Models, Biological; PPAR gamma; Prostaglandin D2; Recombinant Fusion Proteins; Rosiglitazone; Signal Transduction; Smad2 Protein; Thiazolidinediones; Transfection; Transforming Growth Factor beta

2006
Peroxisome proliferator-activated receptor-gamma ligands inhibit proliferation and induce apoptosis in mantle cell lymphoma.
    Anti-cancer drugs, 2006, Volume: 17, Issue:7

    Topics: Annexin A5; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Humans; Ligands; Lymphoma, Mantle-Cell; Pioglitazone; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones

2006
15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism.
    Prostaglandins & other lipid mediators, 2006, Volume: 80, Issue:3-4

    Topics: Cell Line; Cells, Cultured; Chromans; Coculture Techniques; Dinoprost; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Histocompatibility Antigens Class I; HLA-D Antigens; Humans; Immunologic Factors; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Interferon Regulatory Factor-2; Interferon-gamma; Nuclear Proteins; Phosphorylation; Pigment Epithelium of Eye; PPAR gamma; Prostaglandin D2; Rosiglitazone; STAT Transcription Factors; T-Lymphocytes; Thiazolidinediones; Trans-Activators; Troglitazone

2006
Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:6

    Topics: Adenosine Triphosphate; Amino Acid Transport System X-AG; Animals; Blotting, Western; Brain Chemistry; Corticosterone; Deoxyglucose; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Hypoglycemic Agents; In Vitro Techniques; Male; PPAR gamma; Prostaglandin D2; Rats; Rats, Wistar; Restraint, Physical; Rosiglitazone; Stress, Psychological; Synaptophysin; Synaptosomes; Thiazolidinediones

2007
[Stress and inflammatory bowell disease (I.B.D). Therapeutic strategies].
    Anales de la Real Academia Nacional de Medicina, 2006, Volume: 123, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Translocation; Colitis, Ulcerative; Disease Models, Animal; Humans; Immobilization; Immunoglobulin A; Inflammatory Bowel Diseases; PPAR gamma; Prostaglandin D2; Prostaglandins; Rats; Rosiglitazone; Stress, Psychological; Thiazolidinediones; Time Factors

2006
Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism.
    The American journal of pathology, 2007, Volume: 170, Issue:2

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Fatty Acids; Glucose; Humans; Hypoglycemic Agents; Ligands; Lymphoma, T-Cell; Membrane Potential, Mitochondrial; Mitochondria; Neoplasm Proteins; Peroxisome Proliferators; PPAR gamma; Prostaglandin D2; Pyrimidines; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones

2007
Involvement of PPARgamma in human trophoblast invasion.
    Placenta, 2007, Volume: 28 Suppl A

    Topics: Cell Movement; Female; Humans; Ligands; Lipoproteins, LDL; Maternal-Fetal Exchange; Placenta; PPAR gamma; Pregnancy; Pregnancy Trimester, First; Prostaglandin D2; Retinoid X Receptor alpha; Rosiglitazone; Scavenger Receptors, Class E; Thiazolidinediones; Trophoblasts

2007
IL-13 induces expression of CD36 in human monocytes through PPARgamma activation.
    European journal of immunology, 2007, Volume: 37, Issue:6

    Topics: Anilides; Animals; Arachidonic Acids; CD36 Antigens; Cell Line, Tumor; DNA; Enzyme Inhibitors; Erythrocytes; Gene Expression; Humans; Hypoglycemic Agents; Interleukin-13; Macrophages; Macrophages, Peritoneal; Mice; Monocytes; Organophosphonates; Phagocytosis; Phospholipases A; Phospholipases A2; Plasmodium falciparum; PPAR gamma; Prostaglandin D2; Protein Binding; Rosiglitazone; Thiazolidinediones; Transfection

2007
4-Hydroxynonenal and PPARgamma ligands affect proliferation, differentiation, and apoptosis in colon cancer cells.
    Free radical biology & medicine, 2007, Jun-01, Volume: 42, Issue:11

    Topics: Aldehydes; Apoptosis; bcl-2-Associated X Protein; Caco-2 Cells; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Cross-Linking Reagents; Cysteine Proteinase Inhibitors; Drug Synergism; Gene Expression; Humans; Ligands; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones

2007
The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction.
    Gastroenterology, 2007, Volume: 132, Issue:5

    Topics: Animals; Bacterial Translocation; Benzamides; Colitis; Colon; Corticosterone; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Homeostasis; Intestinal Absorption; Ligands; Male; Nitric Oxide Synthase Type II; Peroxidase; PPAR gamma; Prostaglandin D2; Pyridines; Rats; Rats, Wistar; Restraint, Physical; Rosiglitazone; Stress, Physiological; Thiazolidinediones

2007
Activation of peroxisome proliferator-activated receptor gamma inhibits cell growth via apoptosis and arrest of the cell cycle in human colorectal cancer.
    Journal of digestive diseases, 2007, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Humans; Hypoglycemic Agents; Ligands; PPAR gamma; Prostaglandin D2; Rosiglitazone; Signal Transduction; Thiazolidinediones

2007
PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats.
    Bone, 2007, Volume: 41, Issue:4

    Topics: Aging; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Down-Regulation; Gene Expression Regulation, Enzymologic; Ligands; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoblasts; Osteogenesis; PPAR gamma; Prostaglandin D2; Rats; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors; Transforming Growth Factor beta

2007
15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways.
    Experimental cell research, 2007, Oct-01, Volume: 313, Issue:16

    Topics: Animals; Carcinoma; Cell Line, Tumor; Cyclopentanes; Down-Regulation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; NF-kappa B; PPAR gamma; Prostaglandin D2; Receptors, CXCR4; Rosiglitazone; Thiazolidinediones; Time Factors

2007
PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Anilides; Animals; Carboxylic Ester Hydrolases; Cycloheximide; Dietary Fats; Dose-Response Relationship, Drug; Fluorenes; Gene Expression; Leptin; Lipase; Membrane Proteins; Mice; Mice, Inbred Strains; Mice, Knockout; PPAR gamma; Prostaglandin D2; Protein Biosynthesis; RNA, Messenger; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones

2007
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages.
    Antioxidants & redox signaling, 2008, Volume: 10, Issue:2

    Topics: Cell Line; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Hypoglycemic Agents; Immunologic Factors; Interleukin-8; Macrophages; Monocytes; PPAR gamma; Prostaglandin D2; Protein Processing, Post-Translational; Rosiglitazone; Smoke; Smoking; Thiazolidinediones

2008
Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A.
    The EMBO journal, 2007, Dec-12, Volume: 26, Issue:24

    Topics: Anti-Inflammatory Agents; Arachidonic Acid; Arsenites; Chromans; Cyclopentanes; Cytoplasmic Granules; Dinoprostone; Emetine; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Eukaryotic Initiation Factor-4A; Gene Expression Regulation; HeLa Cells; Humans; Hypoglycemic Agents; Inflammation; Poly(A)-Binding Proteins; PPAR gamma; Prostaglandin D2; Prostaglandins A; Protein Biosynthesis; Protein Synthesis Inhibitors; Rosiglitazone; Signal Transduction; Sodium Compounds; T-Cell Intracellular Antigen-1; Thiazolidinediones; TNF Receptor-Associated Factor 2; Troglitazone; Tumor Necrosis Factor-alpha

2007
Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:1

    Topics: Animals; C-Peptide; E1A-Associated p300 Protein; Gene Expression Regulation; Hepatocytes; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Prostaglandin D2; Reperfusion Injury; Retinoid X Receptor alpha; Rosiglitazone; Thiazolidinediones

2008
Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts.
    British journal of pharmacology, 2008, Volume: 153, Issue:7

    Topics: Angiotensin II; Animals; Cell Proliferation; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblasts; Fibrosis; Gene Expression Regulation; Male; Myocardium; Plasminogen Activator Inhibitor 1; PPAR gamma; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta1

2008
Gene alterations by peroxisome proliferator-activated receptor gamma agonists in human colorectal cancer cells.
    International journal of oncology, 2008, Volume: 32, Issue:4

    Topics: Colorectal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; PPAR gamma; Prostaglandin D2; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcriptional Activation

2008
Intrathecal rosiglitazone acts at peroxisome proliferator-activated receptor-gamma to rapidly inhibit neuropathic pain in rats.
    The journal of pain, 2008, Volume: 9, Issue:7

    Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Blotting, Western; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Epoxy Compounds; Gene Expression; Injections, Intraventricular; Injections, Spinal; Male; Motor Activity; Neuralgia; PPAR gamma; Prostaglandin D2; Protein Binding; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Sciatic Nerve; Spinal Cord; Thiazolidinediones

2008
Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:2

    Topics: Alitretinoin; Animals; Cell Proliferation; Collagen Type I; Cytokines; Drug Synergism; Hepatic Stellate Cells; Liver Cirrhosis, Experimental; Male; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Thioacetamide; Tretinoin

2009
Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition.
    World journal of gastroenterology, 2009, Jan-28, Volume: 15, Issue:4

    Topics: Animals; Base Sequence; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Pancreatic Neoplasms; PPAR gamma; Prostaglandin D2; Retinoid X Receptor alpha; RNA, Messenger; RNA, Neoplasm; Rosiglitazone; Thiazolidinediones; Transplantation, Heterologous; Tretinoin; Vascular Endothelial Growth Factor A

2009
Peroxisome proliferator-activated receptor gamma agonists enhance lung maturation in a neonatal rat model.
    Pediatric research, 2009, Volume: 65, Issue:2

    Topics: Adipose Tissue; Animals; Biomarkers; Blood Gas Analysis; Cell Differentiation; Dose-Response Relationship, Drug; Drug Administration Schedule; Epithelial Cells; Injections, Intraperitoneal; Kidney; Liver; Lung; Membrane Proteins; Mesoderm; Models, Animal; Perilipin-2; PPAR gamma; Prostaglandin D2; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory System Agents; Rosiglitazone; Thiazolidinediones; Time Factors

2009
Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
    American journal of respiratory cell and molecular biology, 2009, Volume: 41, Issue:6

    Topics: Acetylation; Actins; Base Sequence; Cell Differentiation; Cells, Cultured; DNA Primers; Fibroblasts; Humans; Ligands; Lung; Oleanolic Acid; p300-CBP Transcription Factors; PPAR gamma; Prostaglandin D2; Pulmonary Fibrosis; Rosiglitazone; Signal Transduction; Smad Proteins; Thiazolidinediones; Transcription Factor AP-1; Transforming Growth Factor beta

2009
Genistein induces adipogenesis but inhibits leptin induction in human synovial fibroblasts.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:7

    Topics: Adipocytes; Adipogenesis; Anti-Inflammatory Agents; Base Sequence; Cell Differentiation; Dexamethasone; DNA Primers; Down-Regulation; Fibroblasts; Genistein; Humans; In Vitro Techniques; Interleukin-6; Interleukin-8; Leptin; Phytoestrogens; PPAR gamma; Prostaglandin D2; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rosiglitazone; Signal Transduction; Synovial Membrane; Thiazolidinediones; Tumor Necrosis Factor-alpha

2009
Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:5

    Topics: Acetylcysteine; Cell Differentiation; Cell Nucleus; Chromans; Dose-Response Relationship, Drug; Enzyme Induction; Fibroblasts; Glutathione; Heme Oxygenase-1; Humans; Ligands; Lung; NF-E2-Related Factor 2; Oleanolic Acid; PPAR gamma; Prostaglandin D2; Protein Transport; Rosiglitazone; Thiazolidinediones; Transcription Factor AP-1; Up-Regulation

2009
Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.
    PloS one, 2009, Nov-04, Volume: 4, Issue:11

    Topics: Animals; Autoimmune Diseases; Cell Line, Tumor; Cell Proliferation; Cytokines; Extracellular Signal-Regulated MAP Kinases; Humans; Hypoglycemic Agents; Leukocytes, Mononuclear; Ligands; Prostaglandin D2; Receptors, Antigen, T-Cell, gamma-delta; Rosiglitazone; STAT5 Transcription Factor; T-Lymphocytes; Thiazolidinediones

2009
Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema.
    Neuropharmacology, 2010, Volume: 58, Issue:2

    Topics: Anilides; Animals; Benzhydryl Compounds; Brain; Central Nervous System Agents; Disease Models, Animal; Edema; Epoxy Compounds; Gene Expression; Inflammation; Male; Pain; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rosiglitazone; Spinal Cord; Thiazolidinediones

2010
PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:6A

    Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blotting, Western; Caco-2 Cells; Colonic Neoplasms; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Ligands; PPAR gamma; Promoter Regions, Genetic; Prostaglandin D2; Protein Binding; Proto-Oncogene Proteins c-myc; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Telomerase; Thiazolidinediones

2010
15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:1

    Topics: Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Lipopolysaccharides; Matrix Metalloproteinase 9; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; PPAR gamma; Prostaglandin D2; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones

2010
Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization.
    Analytical biochemistry, 2010, Apr-01, Volume: 399, Issue:1

    Topics: Anilino Naphthalenesulfonates; Binding, Competitive; Fluorescence Polarization; Fluorescent Dyes; Humans; Ligands; PPAR gamma; Prostaglandin D2; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Rosiglitazone; Thermodynamics; Thiazolidinediones

2010
Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Anilides; Animals; Blood Platelets; Calcium; Collagen; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Phosphorylation; Platelet Aggregation; Platelet Endothelial Cell Adhesion Molecule-1; Platelet Membrane Glycoproteins; PPAR gamma; Prostaglandin D2; Protein-Tyrosine Kinases; Rosiglitazone; Signal Transduction; Spectrometry, Fluorescence; Syk Kinase; Thiazolidinediones; Thrombosis; Time Factors; Tyrosine

2010
Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma.
    Clinical and experimental immunology, 2010, Volume: 160, Issue:3

    Topics: Active Transport, Cell Nucleus; Adult; Apoferritins; Asthma; Catalase; Cell Line; Cell Nucleus; Chemical Industry; Female; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase-1; Humans; Hypoglycemic Agents; Immunologic Factors; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase Kinases; NF-E2-Related Factor 2; Occupational Exposure; Peroxiredoxins; PPAR gamma; Prostaglandin D2; Respiratory Mucosa; Rosiglitazone; Thiazolidinediones; Thioredoxins; Toluene 2,4-Diisocyanate; Transferrin

2010
In vitro effects of peroxisome proliferator-activated receptor-γ ligands on gene expression in lipopolysaccharide-induced endometrial and endometriotic stromal cells.
    Fertility and sterility, 2011, Volume: 95, Issue:2

    Topics: Anti-Inflammatory Agents; Biopsy; Case-Control Studies; Cells, Cultured; Drug Evaluation, Preclinical; Endometriosis; Endometrium; Female; Gene Expression; Humans; Ligands; Lipopolysaccharides; PPAR gamma; Prostaglandin D2; Rosiglitazone; Stromal Cells; Thiazolidinediones; Uterine Diseases

2011
Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles.
    The European respiratory journal, 2011, Volume: 37, Issue:6

    Topics: Anilides; Bronchi; Calcimycin; Cell Line; Cell-Derived Microparticles; Cells, Cultured; Chemokine CCL2; Humans; Interleukin-8; Ionophores; Monocytes; NF-kappa B; Pneumonia; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones; Up-Regulation

2011
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ.
    British journal of pharmacology, 2011, Volume: 163, Issue:7

    Topics: Anilides; Animals; Arachidonic Acids; Benzodioxoles; Biphenyl Compounds; Cannabinoid Receptor Modulators; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Endocannabinoids; Excitatory Postsynaptic Potentials; Glycerides; Hippocampus; Inflammation; Interleukin-1beta; Lipopolysaccharides; Mice; Monoacylglycerol Lipases; Neurons; NF-kappa B; Phosphorylation; Piperidines; PPAR gamma; Prostaglandin D2; Receptor, Cannabinoid, CB1; Rosiglitazone; Signal Transduction; Synaptic Transmission; Thiazolidinediones

2011
Autocrine activation of human monocyte/macrophages by monocyte-derived microparticles and modulation by PPARγ ligands.
    British journal of pharmacology, 2012, Volume: 165, Issue:3

    Topics: Cell-Derived Microparticles; Cells, Cultured; Humans; Interleukin-6; Ligands; Macrophages; Monocytes; NF-kappa B; PPAR gamma; Prostaglandin D2; Rosiglitazone; Superoxides; Thiazolidinediones; Tumor Necrosis Factor-alpha

2012
PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge.
    Cellular immunology, 2012, Volume: 273, Issue:1

    Topics: Allergens; Animals; Cell Movement; Cell Proliferation; Disease Models, Animal; Eosinophilia; Eosinophils; Flow Cytometry; Immunoglobulin E; Inflammation; Interleukins; Leukocyte Count; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones

2012
[PPARgamma agonists against respiratory syncytial virus infection in vitro study].
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2011, Volume: 25, Issue:6

    Topics: Cells, Cultured; Humans; PPAR gamma; Prostaglandin D2; Respiratory Syncytial Viruses; Rosiglitazone; Thiazolidinediones

2011
Inhibition of oxidative stress-elicited AKT activation facilitates PPARγ agonist-mediated inhibition of stem cell character and tumor growth of liver cancer cells.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Glycoproteins; Humans; Liver Neoplasms; Male; Membrane Glycoproteins; Mice; Mice, Nude; NADPH Oxidase 2; NADPH Oxidases; Neoplastic Stem Cells; Oxidative Stress; Peptides; Phenotype; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Ribonucleosides; Rosiglitazone; Thiazolidinediones

2013
15-Deoxy-Δ(12,14)-prostaglandin J2 prevents oxidative injury by upregulating the expression of aldose reductase in vascular smooth muscle cells.
    Free radical research, 2014, Volume: 48, Issue:2

    Topics: Aldehyde Reductase; Animals; Antioxidant Response Elements; Base Sequence; Cells, Cultured; Chromans; Enzyme Induction; Glucose Oxidase; Male; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rosiglitazone; Signal Transduction; Thiazolidinediones; Troglitazone; Up-Regulation

2014
The involvement of peroxisome proliferator activated receptors (PPARs) in prostaglandin F2α production by porcine endometrium.
    Reproductive biology, 2013, Volume: 13, Issue:4

    Topics: Analysis of Variance; Anilides; Animals; Benzamides; Culture Media; Dinoprost; DNA Primers; Endometrium; Estrous Cycle; Female; Indoles; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Pregnancy; Prostaglandin D2; Pyridines; Pyrimidines; Radioimmunoassay; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Swine; Thiazolidinediones

2013
Inhibitory effects of PPARγ ligands on TGF-β1-induced corneal myofibroblast transformation.
    The American journal of pathology, 2014, Volume: 184, Issue:5

    Topics: Actins; Animals; Cats; Cell Line, Transformed; Cell Nucleus; Chromans; Collagen Type I; Cornea; Fibronectins; Fibrosis; Humans; Ligands; Myofibroblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR gamma; Prostaglandin D2; Protein Kinase Inhibitors; Protein Transport; Rosiglitazone; Signal Transduction; Smad Proteins; Thiazolidinediones; Transforming Growth Factor beta1; Troglitazone; Wound Healing

2014
Coordinate regulation between the nuclear receptor peroxisome proliferator-activated receptor-γ and cyclooxygenase-2 in renal epithelial cells.
    Biochemical pharmacology, 2014, Aug-15, Volume: 90, Issue:4

    Topics: Anilides; Animals; Base Sequence; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; DNA Primers; Dogs; Epithelial Cells; Kidney; Phosphorylation; PPAR gamma; Prostaglandin D2; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Sodium Chloride; Thiazolidinediones

2014
Peroxisome proliferator activated receptor ligands affect progesterone and 17β-estradiol secretion by porcine corpus luteum during early pregnancy.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Anilides; Animals; Benzamides; Corpus Luteum; Estradiol; Estrous Cycle; Female; Gene Expression; Indoles; Ligands; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Pregnancy; Progesterone; Prostaglandin D2; Pyridines; Pyrimidines; RNA, Messenger; Rosiglitazone; Swine; Thiazolidinediones

2014
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:6

    Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidney; Kidney Diseases; Male; NAD; NADP; PPAR gamma; Prostaglandin D2; Protective Agents; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Urea; Uric Acid

2014
Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Angiotensin II; Anilides; Animals; Blood Pressure; Body Weight; Cell Proliferation; Cells, Cultured; Cyclin D1; Gene Expression Regulation; Hypoglycemic Agents; Kruppel-Like Transcription Factors; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphorylation; PPAR gamma; Prostaglandin D2; Protein Kinase C; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Thiazolidinediones

2015
Macrophage PPARγ and impaired wound healing in type 2 diabetes.
    The Journal of pathology, 2015, Volume: 236, Issue:4

    Topics: Administration, Cutaneous; Animals; Cells, Cultured; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Humans; Interleukin-1beta; Leg Ulcer; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Phenotype; PPAR gamma; Prostaglandin D2; Receptors, Interleukin-1 Type I; Rosiglitazone; Skin; Thiazolidinediones; Time Factors; Wound Healing

2015
Inhibitory effects of PPARγ ligands on TGF-β1-induced CTGF expression in cat corneal fibroblasts.
    Experimental eye research, 2015, Volume: 138

    Topics: Actins; Animals; Blotting, Western; Cats; Cells, Cultured; Chromans; Collagen Type I; Connective Tissue Growth Factor; Corneal Keratocytes; Fibronectins; Hypoglycemic Agents; JNK Mitogen-Activated Protein Kinases; Ligands; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Prostaglandin D2; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; Transforming Growth Factor beta1; Troglitazone

2015
Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis.
    Oncotarget, 2016, Oct-04, Volume: 7, Issue:40

    Topics: Animals; Cells, Cultured; Fibrosis; Humans; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Phenotype; PPAR gamma; Prostaglandin D2; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta1; Urothelium

2016
Antifibrotic Actions of Peroxisome Proliferator-Activated Receptor γ Ligands in Corneal Fibroblasts Are Mediated by β-Catenin-Regulated Pathways.
    The American journal of pathology, 2017, Volume: 187, Issue:8

    Topics: Actins; Animals; beta Catenin; Cats; Chromans; Collagen Type I; Cornea; Fibroblasts; Fibronectins; Fibrosis; Glycogen Synthase Kinase 3 beta; Lithium Chloride; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR gamma; Prostaglandin D2; Pyrvinium Compounds; Receptors, Transforming Growth Factor beta; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta1; Troglitazone

2017
Rosiglitazone alleviates intrahepatic cholestasis induced by α-naphthylisothiocyanate in mice: The role of circulating 15-deoxy-Δ
    British journal of pharmacology, 2020, Volume: 177, Issue:5

    Topics: 1-Naphthylisothiocyanate; Animals; Cholestasis, Intrahepatic; Humans; Mice; PPAR gamma; Prostaglandin D2; Rosiglitazone

2020
PPARγ alleviates peritoneal fibrosis progression along with promoting GLUT1 expression and suppressing peritoneal mesothelial cell proliferation.
    Molecular and cellular biochemistry, 2022, Volume: 477, Issue:7

    Topics: Animals; Cell Proliferation; Creatinine; Dialysis Solutions; Glucose; Glucose Transporter Type 1; Nitrogen; Peritoneal Fibrosis; PPAR gamma; Prostaglandin D2; Rats; Rosiglitazone; Thiazolidinediones; Transforming Growth Factor beta; Urea

2022