rosiglitazone has been researched along with leptin in 73 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (12.33) | 18.2507 |
| 2000's | 48 (65.75) | 29.6817 |
| 2010's | 14 (19.18) | 24.3611 |
| 2020's | 2 (2.74) | 2.80 |
| Authors | Studies |
|---|---|
| Kallen, CB; Lazar, MA | 1 |
| Auwerx, J; Briggs, MR; De Vos, P; Guerre-Millo, M; Hamann, LG; Lefebvre, AM; Miller, SG; Saladin, R; Staels, B; Wong, K | 1 |
| Boss, O; Burger, AG; Chin, WW; Cusin, I; Juge-Aubry, CE; Meier, CA; Pauli, V; Pernin, A; Rohner-Jeanrenaud, F; Siegrist-Kaiser, CA; Zapf, J | 1 |
| Bing, C; Buckingham, R; Dryden, S; Frankish, HM; Hopkins, D; Pickavance, L; Wang, Q; Williams, G | 1 |
| Carlberg, C; Chiesi, M; Missbach, M; Pignat, W; Spanka, C; Wiesenberg, I | 1 |
| Dandine, M; Dauzats, M; Daviaud, D; Langin, D; Saulnier-Blache, JS; Viguerie-Bascands, N | 1 |
| Brun, S; Carmona, MC; Giralt, M; Iglesias, R; Mampel, T; Villarroya, F; Viñas, O | 1 |
| Auwerx, J; Rieusset, J; Vidal, H | 1 |
| Buckingham, RE; Pickavance, LC; Tadayyon, M; Widdowson, PS; Wilding, JP | 1 |
| Arch, JR; Buckingham, RE; Cai, XJ; Lister, CA; Pickavance, L; Wilding, J; Williams, G; Wilson, S | 1 |
| Braun, M; Brenner, RE; Debatin, KM; Hauner, H; Heinze, E; Melzner, I; Möller, P; Wabitsch, M | 1 |
| Berger, J; Elbrecht, A; Hermanowski-Vosatka, A; Moller, DE; Tanen, M; Thieringer, R; Wright, SD | 1 |
| Buckingham, RE; Pickavance, LC; Wilding, JP | 1 |
| Akanuma, Y; Ezaki, O; Fukayama, M; Hori, W; Ide, T; Itai, A; Kadowaki, T; Kagechika, H; Kamon, J; Kato, S; Kimura, S; Komeda, K; Kubota, N; Miki, H; Motojima, K; Murakami, K; Nagai, R; Shudo, K; Terauchi, Y; Tobe, K; Tsuboyama-Kasaoka, N; Tsuchida, A; Waki, H; Yamauchi, N; Yamauchi, T | 1 |
| Bindl, L; Debatin, KM; Fischer, P; Melzner, I; Möller, P; Tornqvist, H; Wabitsch, M | 1 |
| Arner, P; Dicker, A; Hauner, H; Lönnqvist, F; Näslund, E; Rydén, M; van Harmelen, V | 1 |
| Li, M; Lin, Y; Ma, Y; Zheng, Z | 1 |
| Eggo, MC; Holder, JC; Kumar, S; Patel, NG; Smith, SA | 1 |
| Ehrenborg, E; Eriksson, P; Fisher, RM; Hamsten, A; Kannisto, K; Korsheninnikova, E; Silveira, A; Sutinen, J; Yki-Järvinen, H | 1 |
| Brewer, B; Gavrilova, O; Gonzalez, FJ; Haluzik, M; Lambert, G; Matsusue, K; Reitman, ML; Ward, JM; Yim, SH | 1 |
| Cawthorne, MA; Converset, V; Heller, M; Hochstrasser, DF; Nolan, A; Sanchez, JC; Schmid, G; Sennitt, MV; Wang, S | 1 |
| Donohoe, M; Ellard, S; Hattersley, AT; Owen, KR | 1 |
| Barak, Y; Evans, RM; He, W; Hevener, A; Le, J; Liao, D; Nelson, M; Olefsky, JM; Olson, P; Ong, E | 1 |
| Barnett, AH; Chetty, R; Clark, PM; Fisher, FM; Harte, A; Kumar, S; McTernan, CL; McTernan, PG; Smith, SA; Valsamakis, G | 1 |
| Akbay, E; Aktürk, M; Arslan, M; Ayvaz, G; Cakir, N; Elbeg, S; Karakoç, A; Sancak, B; Taneri, F; Törüner, F | 1 |
| Ahn, IS; Do, MS; Hong, SE; Jung, HS; Rayner, DV | 1 |
| Bai, XY; Goltzman, D; Karaplis, AC; Miao, D; Sorocéanu, MA; Su, H | 1 |
| Alegret, M; Laguna, JC; Roglans, N; Sánchez, RM; Sanguino, E; Vázquez-Carrera, M | 1 |
| Chen, HL; Lei, MX; Sun, ZX; Wu, J | 1 |
| Leiter, EH; Mistry, J; Pan, HJ; Reifsnyder, PC; Xiao, Q; Zhang, W | 1 |
| Boscaro, M; Grossman, AB; Kola, B; Korbonits, M; Rutter, GA | 1 |
| Ishida, Y; Ito, M; Kakutani, M; Matsushita, M; Nishiu, J; Shibata, T; Shindo, M | 1 |
| Crossno, JT; Gill, RG; Grazia, T; Klemm, DJ; Majka, SM | 1 |
| Haider, DG; Ludvik, B; Luger, A; Mittermayer, F; Müller, M; Nowotny, P; Rieger, A; Schindler, K; Wolzt, M | 1 |
| Belury, MA; Liu, LF; Purushotham, A; Wendel, AA | 1 |
| Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, R; Gravina, A; Piccinni, MN; Pricolo, F; Ragonesi, PD; Salvadeo, SA | 1 |
| Bluher, M; Faber, R; Fasshauer, M; Köhler, U; Kralisch, S; Kratzsch, J; Lössner, U; Schubert, A; Sommer, G; Stangl, V; Stepan, H; Stumvoll, M; Vietzke, A | 1 |
| Harte, AL; James, S; Kos, K; Kumar, S; McTernan, PG; O'Hare, JP; Snead, DR | 1 |
| Flier, JS; Gardner, NP; Guan, HP; Kershaw, EE; Lazar, MA; Schupp, M | 1 |
| Feng, CR; He, QJ; Li, Y; Li, YY; Tang, L; Wu, HS; Yang, B; Yang, YS; Yu, JH | 1 |
| Hart, CM; Holguin, F; Rojas, M | 1 |
| Krugluger, W; Krzyzanowska, K; Mittermayer, F; Roden, M; Schernthaner, G; Wolzt, M | 1 |
| Ferrante, AW; Johnson, JA; Trasino, SE; Vasselli, JR | 1 |
| Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Gravina, A; Maffioli, P; Piccinni, MN; Ragonesi, PD; Salvadeo, SA | 1 |
| Baran, I; Cangur, S; Dirican, M; Ersoy, C; Eryilmaz, S; Fazlioglu, M; Gul, CB; Imamoglu, S; Ocak, N; Oz, O; Tuncel, E | 1 |
| Ahn, CW; Cha, BS; Hur, KY; Kang, ES; Kim, HJ; Kim, SK; Lee, HC; Lee, JH; Lim, SK; Shim, WS | 1 |
| Gong, ZC; Hu, PC; Lin, YG; Liu, HL; Liu, ZQ; Sun, H; Wang, D; Wu, J; Yin, JY; Zhang, W; Zhou, HH | 1 |
| Côté, JF; Fradette, J; Vallée, M | 1 |
| Choi, MS; Jeon, SM; Jeong, YJ; Kim, DJ; Kim, HJ; Kwon, JH; Lee, MK; Moon, KD; Park, YB | 1 |
| Aguila, MB; D'Oliveira Silva, G; de Carvalho, JJ; Mandarim-De-Lacerda, CA; Torres, TS | 1 |
| Cheon, HG; Jung, WH; Rhee, SD; Sung, YY | 1 |
| Balabolkin, MI; Klebanova, EM; Kreminskaia, VM; Kuzin, AG; Mamaeva, GG; Tel'nova, ME | 1 |
| Di Blasio, AM; Guzzaloni, G; Liuzzi, A; Maestrini, S; Marzullo, P; Verti, B; Walker, GE; Zurleni, F | 1 |
| Beguin, Y; de Seny, D; Desoroux, A; Malaise, MG; Relic, B; Zeddou, M | 1 |
| McMillen, IC; Morrison, JL; Muhlhausler, BS | 1 |
| Duncan, JD; LaRue, AC; Mehrotra, M; Moussa, O; Nishimoto, E; Ogawa, M; Schulte, BA; Sera, Y; Watson, DK; Watson, PM; Williams, CR | 1 |
| Hong, JH; Hwang, EY; Jeong, YJ; Kim, HJ; Lee, IS | 1 |
| Mandarim-de-Lacerda, CA; Mendonca, Lde S; Silva-Junior, Gde O; Torres, Tda S | 1 |
| Jones, AV; Lamarca, BB; Racusen, LC; Reckelhoff, JF; Romero, DG; Ryan, MJ; Sartori-Valinotti, JC; Venegas-Pont, MR; Yanes, LL | 1 |
| Limor, R; Oron, Y; Rosenthal, T; Stern, N; Younis, F; Zangen, S | 1 |
| German, AJ; Hunter, L; Morris, P; Ryan, VH; Trayhurn, P; Wood, IS | 1 |
| Chang, B; Chen, L; Dong, L; Li, M; Li, XY; Lian, FM; Liu, WK; Qin, PJ; Tong, XL; Wang, J; Yu, B; Zhang, JH; Zhen, Z | 1 |
| Cheon, HG; Jung, WH; Kim, HY; Kim, JY; Kim, KY; Park, JS; Rhee, SD; Sung, YY | 1 |
| Karbowska, J; Kochan, Z | 1 |
| Knight, BB; Nagalingam, A; Oberlick, E; Saxena, NK; Sharma, D; Taliaferro-Smith, L | 1 |
| Koc, M; Kovácová, Z; Kracmerová, J; Langin, D; Malisová, L; Rossmeislová, L; Siklová-Vítková, M; Stich, V; Tencerová, M; Viquerie, N | 1 |
| Arnould, T; Geeraert, B; Holvoet, P; Hulsmans, M; Tsatsanis, C | 1 |
| Diano, S; Horvath, TL; Jeong, JK; Long, L; Toda, C | 1 |
| Cander, S; Ersoy, C; Guclu, M; Oz Gul, O; Ozkaya, G; Sarandol, E; Unal, O | 1 |
| Guo, DF; Liu, X; Lu, KT; Mukohda, M; Rahmouni, K; Sigmund, CD; Stump, M | 1 |
| Aslanidis, C; Buechler, C; Eisinger, K; Haberl, EM; Krautbauer, S; Neumann, M; Pohl, R; Rein-Fischboeck, L; Schacherer, D; Weiss, TS; Zimny, S | 1 |
| Cortés, V; Ezquer, F; Figueroa, AM; González-Hodar, L; Robledo, F; Tapia, P | 1 |
| Liu, JH; Liu, YY; Ruan, HJ; Song, CR; Sui, YL; Zhao, C; Zhu, JZ | 1 |
1 review(s) available for rosiglitazone and leptin
| Article | Year |
|---|---|
Expanding role of AMPK in endocrinology.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Appetite Regulation; Cannabinoids; Cytokines; Endocrine System; Fatty Acid Synthases; Ghrelin; Glucose; Humans; Hypothalamic Hormones; Insulin; Leptin; Metformin; Models, Biological; Multienzyme Complexes; Peptide Hormones; Protein Serine-Threonine Kinases; Receptors, Adrenergic; Resistin; Rosiglitazone; Thiazolidinediones; Thioctic Acid | 2006 |
8 trial(s) available for rosiglitazone and leptin
| Article | Year |
|---|---|
[Effect of rosiglitazone on insulin resistance and hyperandrogenism in polycystic ovary syndrome].
Topics: Administration, Oral; Adult; Androstenedione; Blood Glucose; Body Weight; Female; Follicle Stimulating Hormone; Humans; Hyperandrogenism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Lipids; Luteinizing Hormone; Menstruation; Neuropeptide Y; Ovulation; Polycystic Ovary Syndrome; Rosiglitazone; Testosterone; Thiazoles; Thiazolidinediones; Treatment Outcome | 2002 |
Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy.
Topics: Adipose Tissue; Adult; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Female; HIV Infections; Humans; Hyperinsulinism; Hypertriglyceridemia; Interleukin-6; Leptin; Lipodystrophy; Liver; Male; Middle Aged; Organ Specificity; Plasminogen Activator Inhibitor 1; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Subcutaneous Tissue; Thiazolidinediones; Transcription Factors | 2003 |
Effect of rosiglitazone on visfatin and retinol-binding protein-4 plasma concentrations in HIV-positive patients.
Topics: Adiponectin; Adipose Tissue; Adult; Cytokines; Female; HIV Seropositivity; Humans; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Middle Aged; Nicotinamide Phosphoribosyltransferase; Regression Analysis; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Rosiglitazone; Thiazolidinediones | 2007 |
Telmisartan and irbesartan therapy in type 2 diabetic patients treated with rosiglitazone: effects on insulin-resistance, leptin and tumor necrosis factor-alpha.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Irbesartan; Leptin; Lipids; Male; Middle Aged; Rosiglitazone; Telmisartan; Tetrazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2006 |
Adiponectin concentrations increase during acute FFA elevation in humans treated with rosiglitazone.
Topics: Adiponectin; Adult; Blood Glucose; C-Reactive Protein; Double-Blind Method; Fatty Acids, Nonesterified; Humans; Hypoglycemic Agents; Infusion Pumps; Leptin; Lipids; Male; Placebos; Resistin; Rosiglitazone; Thiazolidinediones; Time Factors | 2007 |
Rosiglitazone therapy improves insulin resistance parameters in overweight and obese diabetic patients intolerant to metformin.
Topics: Adiponectin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Italy; Leptin; Male; Metformin; Middle Aged; Obesity; Overweight; Resistin; Rosiglitazone; Single-Blind Method; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2008 |
Arterial elasticity and plasma levels of adiponectin and leptin in type 2 diabetic patients treated with thiazolidinediones.
Topics: Adiponectin; Arteries; Blood Glucose; Body Mass Index; Capillary Resistance; Diabetes Mellitus, Type 2; Elasticity; Female; Glycemic Index; Humans; Hypoglycemic Agents; Leptin; Lipids; Male; Middle Aged; Pioglitazone; Placebos; Rosiglitazone; Thiazolidinediones | 2008 |
Effect of Rosiglitazone and Insulin Combination Therapy on Inflammation Parameters and Adipocytokine Levels in Patients with Type 1 DM.
Topics: Adipokines; Adiponectin; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Fibrinogen; Humans; Hyperglycemia; Hypoglycemic Agents; Inflammation; Insulin; Insulin Secretion; Leptin; Male; Middle Aged; Prognosis; Prospective Studies; Resistin; Rosiglitazone; Thiazolidinediones; Young Adult | 2015 |
64 other study(ies) available for rosiglitazone and leptin
| Article | Year |
|---|---|
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Gene Expression Regulation; Hypoglycemic Agents; Leptin; Mice; Molecular Sequence Data; Obesity; Oligodeoxyribonucleotides; Protein Binding; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1996 |
Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma.
Topics: Adipocytes; Adipose Tissue; Animals; Base Sequence; DNA Primers; Enzyme Activation; Gene Expression; Humans; Leptin; Liver; Molecular Sequence Data; Organ Size; Pioglitazone; Promoter Regions, Genetic; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1996 |
Direct effects of leptin on brown and white adipose tissue.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Animals; Carrier Proteins; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Gene Expression; Glucose; Hypoglycemic Agents; Janus Kinase 1; Leptin; Lipoprotein Lipase; Malate Dehydrogenase; Male; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Cell Surface; Receptors, Leptin; Rosiglitazone; STAT1 Transcription Factor; Thiazoles; Thiazolidinediones; Trans-Activators | 1997 |
Increased feeding in fatty Zucker rats by the thiazolidinedione BRL 49653 (rosiglitazone) and the possible involvement of leptin and hypothalamic neuropeptide Y.
Topics: Animals; Appetite Stimulants; Body Weight; Eating; Hyperphagia; Hypoglycemic Agents; Hypothalamus; Leptin; Male; Neuropeptide Y; Proteins; Rats; Rats, Wistar; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones | 1997 |
Specific activation of the nuclear receptors PPARgamma and RORA by the antidiabetic thiazolidinedione BRL 49653 and the antiarthritic thiazolidinedione derivative CGP 52608.
Topics: 3T3 Cells; Animals; Arthritis, Experimental; Cell Nucleus; Dexamethasone; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Mice; Proteins; Rats; Rats, Inbred Lew; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiosemicarbazones; Transcription Factors; Triglycerides | 1998 |
Increase in uncoupling protein-2 mRNA expression by BRL49653 and bromopalmitate in human adipocytes.
Topics: Adipocytes; Adipose Tissue; Adult; Cells, Cultured; Culture Techniques; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Ion Channels; Leptin; Membrane Transport Proteins; Middle Aged; Mitochondrial Proteins; Palmitates; Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha; Uncoupling Protein 2 | 1999 |
Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth.
Topics: Animals; Bezafibrate; Carrier Proteins; Clofibrate; DNA-Binding Proteins; Eating; Fatty Acids, Nonesterified; Female; Gene Expression Regulation, Developmental; Hypolipidemic Agents; Ion Channels; Leptin; Male; Mice; Mitochondria, Muscle; Mitochondrial Proteins; Muscle Development; Muscle, Skeletal; Peroxisome Proliferators; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Uncoupling Protein 3 | 1999 |
Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes.
Topics: Adipocytes; Adipose Tissue; Adult; Aged; DNA-Binding Proteins; Female; Gene Expression Regulation; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Ion Channels; Leptin; Male; Membrane Transport Proteins; Middle Aged; Mitochondrial Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Obesity; Phosphatidylinositol 3-Kinases; Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Transcription Factors; Transcription, Genetic; Uncoupling Protein 2 | 1999 |
Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution.
Topics: Animals; Body Weight; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Hemodilution; Hemodynamics; Hypoglycemic Agents; Insulin; Leptin; Male; Obesity; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Thiazolidinediones | 1999 |
Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and zucker diabetic fatty rats and effects of rosiglitazone.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hyperglycemia; Hypoglycemic Agents; Hypothalamus; Insulin; Intracellular Signaling Peptides and Proteins; Leptin; Neuropeptides; Obesity; Orexins; Protein Precursors; Rats; Rats, Zucker; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thinness; Transcription, Genetic | 2000 |
Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation.
Topics: Adipocytes; Adipose Tissue; Cell Differentiation; Cell Division; Cells, Cultured; Female; Gene Expression; Glypicans; Growth Disorders; Heparan Sulfate Proteoglycans; Humans; Infant; Insulin; Karyotyping; Leptin; Male; Models, Biological; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Syndrome; Thiazoles; Thiazolidinediones; Transcription Factors | 2001 |
Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta -hydroxysteroid dehydrogenase type 1 expression and activity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3 Cells; Adipocytes; Animals; Cycloheximide; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Hydroxysteroid Dehydrogenases; Kinetics; Leptin; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic | 2001 |
Insulin-sensitizing action of rosiglitazone is enhanced by preventing hyperphagia.
Topics: Animals; Body Weight; Carrier Proteins; Eating; Food Deprivation; Hyperphagia; Hypoglycemic Agents; Hypothalamus; Insulin Resistance; Ion Channels; Leptin; Male; Mitochondrial Proteins; Neuropeptide Y; Obesity; Rats; Rats, Wistar; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Uncoupling Protein 3 | 2001 |
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Topics: 3T3 Cells; Adipose Tissue; Animals; Benzhydryl Compounds; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Epoxy Compounds; Fatty Acids; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Leptin; Mice; Mice, Knockout; Nicotinic Acids; Obesity; Receptors, Adrenergic, beta-3; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors | 2001 |
Induction of adipocyte differentiation by a thiazolidinedione in cultured, subepidermal, fibroblast-like cells of an infant with congenital generalized lipodystrophy.
Topics: Adipocytes; Cell Differentiation; Cells, Cultured; Epidermis; Fibroblasts; Gene Expression; Humans; Infant, Newborn; Leptin; Lipids; Lipodystrophy; Male; Rosiglitazone; Stem Cells; Thiazoles; Thiazolidinediones | 2002 |
Increased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes.
Topics: Adipocytes; Adult; Aged; Body Mass Index; Cell Differentiation; Female; Glycerol; Humans; Hypoglycemic Agents; Leptin; Lipolysis; Male; Middle Aged; Norepinephrine; Obesity; Omentum; RNA, Messenger; Rosiglitazone; Skin; Thiazoles; Thiazolidinediones; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2002 |
Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation.
Topics: Adipocytes; Androstadienes; Cell Differentiation; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Leptin; Lipid Metabolism; Lipids; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Rosiglitazone; Signal Transduction; Sirolimus; Stem Cells; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha; Wortmannin | 2003 |
Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes.
Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Fatty Liver; Hyperglycemia; Insulin Resistance; Leptin; Lipoprotein Lipase; Lipoproteins, VLDL; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; Receptors, Leptin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Triglycerides | 2003 |
Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice.
Topics: Animals; Electrophoresis, Gel, Two-Dimensional; Hypoglycemic Agents; Insulin Resistance; Leptin; Mice; Mice, Inbred C57BL; Obesity; Rosiglitazone; Thiazolidinediones | 2003 |
Response to treatment with rosiglitazone in familial partial lipodystrophy due to a mutation in the LMNA gene.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Lipoatrophic; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Lamin Type A; Leptin; Mutation; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Skinfold Thickness; Thiazolidinediones; Transcription Factors | 2003 |
Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Hypoglycemic Agents; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Leptin; Lipodystrophy; Liver; Liver Function Tests; Metabolic Syndrome; Mice; Mice, Knockout; Muscle, Skeletal; Organ Specificity; Proteins; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors | 2003 |
Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes.
Topics: Adipocytes; Adult; Blotting, Western; Case-Control Studies; Cell Differentiation; Cross Reactions; Diabetes Mellitus, Type 2; Female; Gene Expression; Glucose; Hormones, Ectopic; Humans; Hypoglycemic Agents; Insulin; Intercellular Signaling Peptides and Proteins; Leptin; Lipid Metabolism; Lipolysis; Male; Middle Aged; Recombinant Proteins; Resistin; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Stem Cells; Subcutaneous Tissue; Thiazolidinediones | 2003 |
Effects of PPARgamma and PPARalpha agonists on serum leptin levels in diet-induced obese rats.
Topics: Adipose Tissue; Animals; Dietary Fats; Energy Metabolism; Gemfibrozil; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Leptin; Male; Obesity; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Weight Gain | 2004 |
Effect of retinoic acid on leptin, glycerol, and glucose levels in mature rat adipocytes in vitro.
Topics: Adipocytes; Alitretinoin; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation; Glycerol; Isomerism; Leptin; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; Retinoid X Receptors; Rosiglitazone; Thiazolidinediones; Tretinoin | 2004 |
Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis.
Topics: Animals; Apoptosis; Biomarkers; Blood Glucose; Bone and Bones; Bone Density; Calcium; Cells, Cultured; Diabetes Mellitus; Histocytochemistry; Hypoglycemic Agents; Image Processing, Computer-Assisted; Leptin; Male; Mice; Mice, Inbred C57BL; Osteoblasts; Osteocalcin; Osteocytes; Parathyroid Hormone; Rosiglitazone; Thiazolidinediones | 2004 |
Different response of senescent female Sprague-Dawley rats to gemfibrozil and rosiglitazone administration.
Topics: Adipose Tissue; Aging; Animals; Blood Glucose; Body Weight; Cholesterol; Diet; DNA-Binding Proteins; Fatty Acids, Nonesterified; Female; Gemfibrozil; Hepatocyte Nuclear Factor 4; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Leptin; Liver; Liver X Receptors; Orphan Nuclear Receptors; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Triglycerides | 2005 |
[Effects of rosiglitazone on serum leptin and insulin resistance in patients with Type 2 diabetes].
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Middle Aged; Regression Analysis; Rosiglitazone; Thiazolidinediones | 2004 |
Differential endocrine responses to rosiglitazone therapy in new mouse models of type 2 diabetes.
Topics: Adiponectin; Analysis of Variance; Animals; Biomarkers; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Glucose Intolerance; Hypoglycemic Agents; Insulin; Leptin; Male; Mice; Mice, Congenic; Mice, Inbred NOD; Mice, Obese; Obesity; Phenotype; Plasminogen Activator Inhibitor 1; Quantitative Trait, Heritable; Recombination, Genetic; Resistin; Rosiglitazone; Species Specificity; Syndrome; Thiazolidinediones | 2006 |
JTP-426467 acts as a selective antagonist for peroxisome proliferator-activated receptor gamma in vitro and in vivo.
Topics: Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Benzoxazoles; Blood Glucose; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; HeLa Cells; Humans; Hypoglycemic Agents; Leptin; Male; Mice; Obesity; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Weight Gain | 2006 |
Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells.
Topics: Adipocytes; Adiponectin; Animals; Blotting, Western; Bone Marrow Cells; Bone Marrow Transplantation; Carrier Proteins; CD11 Antigens; Cell Differentiation; Collagenases; Dietary Fats; Female; Flow Cytometry; Green Fluorescent Proteins; Hypoglycemic Agents; Leptin; Leukocyte Common Antigens; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Phase-Contrast; Perilipin-1; Phosphoproteins; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Stem Cells; Thiazolidinediones | 2006 |
Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adiposity; Animals; Apoptosis; Body Weight; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Hypoglycemic Agents; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Leptin; Linoleic Acids, Conjugated; Lipid Metabolism; Lipoproteins, VLDL; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors; Triglycerides | 2007 |
Secretory products from human adipocytes impair endothelial function via nuclear factor kappaB.
Topics: Adipocytes; Adipokines; Apoptosis; Cell Adhesion; Cells, Cultured; E-Selectin; Endothelium, Vascular; Female; Humans; Intercellular Adhesion Molecule-1; Leptin; Leupeptins; NF-kappa B; Resistin; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2008 |
Secretion of neuropeptide Y in human adipose tissue and its role in maintenance of adipose tissue mass.
Topics: Adipocytes; Adult; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Insulin; Leptin; Neuropeptide Y; PPAR gamma; Rosiglitazone; Subcutaneous Fat, Abdominal; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2007 |
PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Anilides; Animals; Carboxylic Ester Hydrolases; Cycloheximide; Dietary Fats; Dose-Response Relationship, Drug; Fluorenes; Gene Expression; Leptin; Lipase; Membrane Proteins; Mice; Mice, Inbred Strains; Mice, Knockout; PPAR gamma; Prostaglandin D2; Protein Biosynthesis; RNA, Messenger; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones | 2007 |
The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Blood Glucose; Cell Differentiation; Cell Line, Tumor; Glucose; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; In Vitro Techniques; Indoleacetic Acids; Indoles; Insulin; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; PPAR alpha; PPAR gamma; Resistin; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones | 2007 |
The peroxisome proliferator activated receptor gamma (PPARgamma) ligand rosiglitazone modulates bronchoalveolar lavage levels of leptin, adiponectin, and inflammatory cytokines in lean and obese mice.
Topics: Adiponectin; Animals; Biomarkers; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Hypoglycemic Agents; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Treatment Outcome | 2007 |
Prolonged decrease of adipocyte size after rosiglitazone treatment in high- and low-fat-fed rats.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adiposity; Animals; Biopsy; Body Weight; Cell Size; Dietary Fats; Eating; Female; Hypoglycemic Agents; Insulin; Leptin; Random Allocation; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Triglycerides | 2007 |
Rosiglitazone improves insulin sensitivity with increased serum leptin levels in patients with type 2 diabetes mellitus.
Topics: Adult; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Middle Aged; Rosiglitazone; Thiazolidinediones; Waist-Hip Ratio | 2008 |
Impact of genetic polymorphisms of leptin and TNF-alpha on rosiglitazone response in Chinese patients with type 2 diabetes.
Topics: Adult; Aged; Blood Glucose; China; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Middle Aged; Polymorphism, Genetic; Rosiglitazone; Thiazolidinediones; Triglycerides; Tumor Necrosis Factor-alpha | 2008 |
Adipose-tissue engineering: taking advantage of the properties of human adipose-derived stem/stromal cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adult; Adult Stem Cells; Ascorbic Acid; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Extracellular Matrix; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Leptin; Lipectomy; Lipoprotein Lipase; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Serum; Stromal Cells; Subcutaneous Fat; Thiazolidinediones; Tissue Engineering | 2009 |
Beneficial effect of chungkukjang on regulating blood glucose and pancreatic beta-cell functions in C75BL/KsJ-db/db mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Fermentation; Glucagon; Glucokinase; Glycated Hemoglobin; Glycine max; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Isoflavones; Leptin; Liver; Male; Mice; Mice, Inbred C57BL; Pancreas; Rosiglitazone; Soybean Proteins; Thiazolidinediones | 2008 |
Effects of rosiglitazone (a peroxysome proliferator-activated receptor gamma agonist) on the blood pressure and aortic structure in metabolically programmed (perinatal low protein) rats.
Topics: Animals; Aorta; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Diet, Protein-Restricted; Disease Models, Animal; Elasticity; Female; Hypertension; Hypertrophy; Insulin; Leptin; Male; Nitric Oxide Synthase Type III; PPAR gamma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Rosiglitazone; Thiazolidinediones; Tunica Media | 2008 |
Leptin inhibits rosiglitazone-induced adipogenesis in murine primary adipocytes.
Topics: Adipocytes; Adipogenesis; Animals; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Leptin; Mice; Mice, Inbred C57BL; Phosphorylation; PPAR gamma; Rosiglitazone; Signal Transduction; STAT1 Transcription Factor; Thiazolidinediones; Time Factors; Vidarabine | 2008 |
[Avandia and avandamet in the treatment of patients with diabetes mellitus type 2: effects on secretion of some fat tissue hormones].
Topics: Adiponectin; Adipose Tissue; Diabetes Mellitus, Type 2; Drug Combinations; Female; Fibrinolytic Agents; Ghrelin; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Middle Aged; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones | 2008 |
Subcutaneous abdominal adipose tissue subcompartments: potential role in rosiglitazone effects.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipocytes; Adiponectin; Cell Differentiation; Down-Regulation; Female; Glucose; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Intra-Abdominal Fat; Leptin; Lipoprotein Lipase; Male; Middle Aged; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones | 2008 |
Genistein induces adipogenesis but inhibits leptin induction in human synovial fibroblasts.
Topics: Adipocytes; Adipogenesis; Anti-Inflammatory Agents; Base Sequence; Cell Differentiation; Dexamethasone; DNA Primers; Down-Regulation; Fibroblasts; Genistein; Humans; In Vitro Techniques; Interleukin-6; Interleukin-8; Leptin; Phytoestrogens; PPAR gamma; Prostaglandin D2; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rosiglitazone; Signal Transduction; Synovial Membrane; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2009 |
Rosiglitazone increases the expression of peroxisome proliferator-activated receptor-gamma target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation.
Topics: Adiponectin; Adipose Tissue; Animals; Female; Fetus; Glycerol-3-Phosphate Dehydrogenase (NAD+); Insulin; Leptin; Lipoprotein Lipase; Liver; Maternal Nutritional Physiological Phenomena; Muscle, Skeletal; Phosphoenolpyruvate Carboxykinase (GTP); PPAR alpha; PPAR gamma; Pregnancy; Pregnancy, Animal; RNA, Messenger; Rosiglitazone; Sheep; Thiazolidinediones; Trans-Activators | 2009 |
Hematopoietic stem cell origin of adipocytes.
Topics: Adipocytes; Animals; Antigens, Differentiation; Bone Marrow Transplantation; Carrier Proteins; Cell Differentiation; Cells, Cultured; Diet; Fatty Acid-Binding Proteins; Female; Hematopoietic Stem Cells; Hypoglycemic Agents; Leptin; Male; Mice; Mice, Transgenic; Perilipin-1; Phosphoproteins; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transplantation, Homologous | 2009 |
Artemisia capillaris inhibits lipid accumulation in 3T3-L1 adipocytes and obesity in C57BL/6J mice fed a high fat diet.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Artemisia; Carnitine O-Palmitoyltransferase; Cell Line; Diet; Dietary Fats; Disease Models, Animal; Fatty Acids, Nonesterified; Flavonoids; Glycerolphosphate Dehydrogenase; Hypolipidemic Agents; Leptin; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Obesity; Phenols; Phytotherapy; Plant Extracts; PPAR gamma; Rosiglitazone; Thiazolidinediones; Triglycerides | 2009 |
Rosiglitazone (peroxisome proliferator-activated receptor-gamma) counters hypertension and adverse cardiac and vascular remodeling in 2K1C hypertensive rats.
Topics: Animals; Aorta; Carotid Artery, Common; Hypertension, Renovascular; Immunohistochemistry; Insulin; Leptin; Male; Myocardium; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tunica Intima | 2011 |
Rosiglitazone reduces blood pressure in female Dahl salt-sensitive rats.
Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; Chemokine CCL2; Cholesterol; Estradiol; Feeding Behavior; Female; Gene Expression Regulation; Immunohistochemistry; Inflammation; Insulin; Kidney; Leptin; Nitrates; Nitrites; Osteopontin; Ovariectomy; Rats; Rats, Inbred Dahl; RNA, Messenger; Rosiglitazone; Thiazolidinediones | 2010 |
Telmisartan ameliorates hyperglycemia and metabolic profile in nonobese Cohen-Rosenthal diabetic hypertensive rats via peroxisome proliferator activator receptor-gamma activation.
Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Humans; Hyperglycemia; Hypertension; Insulin; Insulin Resistance; Leptin; PPAR gamma; Rats; Rats, Inbred SHR; Rosiglitazone; Telmisartan; Thiazolidinediones; Tumor Necrosis Factor-alpha; Weight Gain | 2010 |
Adipokine expression and secretion by canine adipocytes: stimulation of inflammatory adipokine production by LPS and TNFalpha.
Topics: Adipocytes; Adiponectin; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Dexamethasone; Dogs; Female; Hypoglycemic Agents; Leptin; Lipopolysaccharides; Male; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2010 |
Anti-diabetic effects of a Coptis chinensis containing new traditional Chinese medicine formula in type 2 diabetic rats.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Area Under Curve; Blood Glucose; Bupleurum; Coptis; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Glucose Tolerance Test; Glucose Transporter Type 4; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Leptin; Lipid Metabolism; Lipids; Muscle, Skeletal; Phytotherapy; Rats; Rats, Inbred OLETF; Rheum; Rosiglitazone; Scutellaria baicalensis; Thiazolidinediones | 2011 |
Inhibitory effect of leptin on rosiglitazone-induced differentiation of primary adipocytes prepared from TallyHO/Jng mice.
Topics: Adipocytes; Adipogenesis; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Flavonoids; Leptin; Mice; Mice, Inbred Strains; PPAR gamma; Receptors, Leptin; RNA, Messenger; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones | 2011 |
Intermittent fasting up-regulates Fsp27/Cidec gene expression in white adipose tissue.
Topics: Adipocytes; Adipose Tissue, White; Animals; CCAAT-Enhancer-Binding Protein-alpha; Fasting; Insulin; Leptin; Male; Pioglitazone; PPAR gamma; Rats; Rats, Wistar; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Triglycerides; Up-Regulation | 2012 |
Integral role of PTP1B in adiponectin-mediated inhibition of oncogenic actions of leptin in breast carcinogenesis.
Topics: Adiponectin; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Leptin; MCF-7 Cells; Mice; Mice, Nude; Neoplasm Invasiveness; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Rosiglitazone; Signal Transduction; Thiazolidinediones | 2013 |
Weight loss improves the adipogenic capacity of human preadipocytes and modulates their secretory profile.
Topics: Adipocytes; Adipogenesis; Adiponectin; Cells, Cultured; Chemokine CCL2; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-8; Leptin; Obesity; PPAR gamma; Rosiglitazone; Thiazolidinediones; Weight Loss | 2013 |
PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression.
Topics: Adipocytes; Adiponectin; Animals; Chemokine CCL2; Diet, High-Fat; Fenofibrate; Inflammation; Insulin; Insulin Resistance; Interleukin-1 Receptor-Associated Kinases; Leptin; Macrophages; Mice; Mice, Inbred C57BL; Obesity; Peroxisome Proliferator-Activated Receptors; Plaque, Atherosclerotic; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones | 2013 |
PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding.
Topics: Anilides; Animals; Diet, High-Fat; Energy Metabolism; Female; Glucose; Hyperphagia; Insulin Resistance; Leptin; Male; Mice; Motor Activity; Neurons; PPAR gamma; Pro-Opiomelanocortin; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones | 2014 |
Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance.
Topics: 3T3 Cells; Adipogenesis; Animals; Body Weight; Brain; Cell Line; Diet, High-Fat; Energy Metabolism; Female; HEK293 Cells; Homeostasis; Humans; Leptin; Male; Mice; Neurons; Obesity; PPAR gamma; Pro-Opiomelanocortin; Rosiglitazone; Thiazolidinediones; Weight Gain | 2016 |
Hepatic chemerin mRNA expression is reduced in human nonalcoholic steatohepatitis.
Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Case-Control Studies; Cell Line; Cells, Cultured; Chemokines; Comorbidity; Cytokines; Diabetes Mellitus, Type 2; Female; Fibroblast Growth Factors; Hep G2 Cells; Hepatic Stellate Cells; Hepatocytes; Hepcidins; Humans; Hydrocarbons, Fluorinated; Hypertension; Hypoglycemic Agents; In Vitro Techniques; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Leptin; Lipocalin-2; Liver; Liver X Receptors; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Severity of Illness Index; Sulfonamides; Thiazolidinediones; Waist-Hip Ratio; Young Adult | 2017 |
Spheroids derived from the stromal vascular fraction of adipose tissue self-organize in complex adipose organoids and secrete leptin.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Chondrogenesis; Immunophenotyping; Insulin; Leptin; Lipolysis; Mice; Organoids; Osteogenesis; Primary Cell Culture; Rosiglitazone | 2023 |
Effects of Moringa Oleifera Leaf Extract Plus Rosiglitazone on Serum Leptin and Glucose and Lipid Metabolism in Type 2 Diabetic Rats.
Topics: Animals; beta Catenin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glycogen Synthase Kinase 3 beta; Hypoglycemic Agents; Leptin; Lipid Metabolism; Lipids; Male; Moringa oleifera; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Rosiglitazone; Tumor Necrosis Factor-alpha | 2023 |