Page last updated: 2024-08-25

rosiglitazone and gw0742

rosiglitazone has been researched along with gw0742 in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's8 (53.33)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Abad, MC; Askari, HB; De, D; Gaul, MD; Geisler, JG; Kasturi, J; Kemmerer, M; Kim, AJ; Lenhard, JM; Lin, L; Liu, J; O'Neill, JC; Patch, RJ; Player, MR; Rentzeperis, D; Searle, LL; Zhu, X1
Carta, G; Fayne, D; Lloyd, DG; Nevin, DK; Peters, MB1
Acevedo, O; Amin, RH; Boncher, T; Bonkowski, B; Gathiaka, S; Huggins, K; Nanayakkara, G; Patel, A; Patel, S; Rong, Y; Shane, ME; Smith, F; Wieczorek, J; Wyble, J1
Büssow, K; de Groot, JC; Kawamoto, K; Krausze, J; Sauer, S; Schroeder, FC; Weidner, C1
Dou, XZ; Duerfeldt, AS; Ma, JX; Nath, D; Shin, Y1
Deng, F; Li, Y; Li, Z; Zhang, D; Zhang, L; Zhou, Z1
Bourne, PC; Dou, X; Duerfeldt, AS; Ma, JX; Nath, D; Nurmemmedov, E; Shin, H1
Andy, D; Erhardt, PW; Farris, JT; Heck, B; Heck, BE; Kim, DH; Kress, BJ; Mayo, JR; Sarver, JG; Trendel, JA1
Cai, Z; Han, J; Li, Z; Ren, Q; Wang, B; Zhang, L; Zhou, Z1
Cai, Z; Deng, L; Geng, X; Hu, L; Jiao, S; Li, Z; Ren, Q; Wang, B; Yang, Y; Zhang, L; Zhou, Z1
Cai, Z; Chen, L; He, Y; Li, Z; Yang, B; Zhang, C; Zhang, L; Zhou, Z1
Alves, PS; Bhattacharyya, M; Brand, GD; Cummins, CL; Ferreira, TAM; Grouleff, J; Krause, H; Leite, JRSA; Liu, J; Magomedova, L; Moreira, DC; Nogueira, PCN; Oliveira, AS; Poda, G; Queiroz, FJG; Romeiro, LAS; Sahin, C; Silveira, ER; Tiefenbach, J; Uehling, D1
Bronfman, M; Leisewitz, AV; Loyola, G; Martinez, GR; Urrutia, CR1
Decsi, T; Liebisch, G; Marosvölgyi, T; Mihály, J; Rühl, R; Schmitz, G; Weiss, K1
Agarwal, AK; Garg, A; Sankella, S1

Other Studies

15 other study(ies) available for rosiglitazone and gw0742

ArticleYear
Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents.
    Journal of medicinal chemistry, 2011, Feb-10, Volume: 54, Issue:3

    Topics: Administration, Oral; Animals; Binding, Competitive; Biological Availability; Crystallography, X-Ray; Diabetes Mellitus; Dogs; ERRalpha Estrogen-Related Receptor; Ethers; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Ligands; Macaca fascicularis; Male; Mice; Mice, Knockout; Models, Molecular; Molecular Structure; Obesity; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Structure-Activity Relationship; Thiazolidinediones; Triglycerides

2011
Integrated virtual screening for the identification of novel and selective peroxisome proliferator-activated receptor (PPAR) scaffolds.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Benzamides; Binding, Competitive; Databases, Factual; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; HEK293 Cells; Humans; Models, Molecular; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Protein Conformation; Pyrazoles; Pyrrolidinones; Structure-Activity Relationship; Thiazoles; Thiobarbiturates

2012
Design, development and evaluation of novel dual PPARδ/PPARγ agonists.
    Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3

    Topics: Dose-Response Relationship, Drug; Drug Combinations; Drug Design; Hypoglycemic Agents; Models, Molecular; Molecular Docking Simulation; Molecular Structure; PPAR delta; PPAR gamma; Protein Binding

2013
Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.
    Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4

    Topics: Crystallography, X-Ray; Drug Partial Agonism; Genes, Reporter; HEK293 Cells; Humans; Molecular Structure; PPAR gamma; Salicylates; Stereoisomerism

2013
Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARα selective agonists: New leads for oculovascular conditions.
    Bioorganic & medicinal chemistry letters, 2018, 09-01, Volume: 28, Issue:16

    Topics: Dose-Response Relationship, Drug; Eye Diseases; Humans; Ligands; Models, Molecular; Molecular Structure; PPAR alpha; Quinolines; Structure-Activity Relationship; Vascular Diseases

2018
Design, synthesis, and biological evaluation of novel pan agonists of FFA1, PPARγ and PPARδ.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Animals; CHO Cells; Cricetulus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Design; Glucose Tolerance Test; HEK293 Cells; Hep G2 Cells; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred ICR; Mice, Obese; Models, Molecular; Molecular Structure; PPAR delta; PPAR gamma; Receptors, G-Protein-Coupled; Structure-Activity Relationship

2018
Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Animals; Benzylamines; Capillary Permeability; Cell Line; Diabetic Retinopathy; Disease Models, Animal; Drug Design; Drug Discovery; Humans; PPAR alpha; Rats; Retinal Diseases; Streptozocin

2020
Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis.
    Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10

    Topics: Animals; Cell Differentiation; Disease Models, Animal; Drug Design; Female; Femur; Humans; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteogenesis; Osteoporosis; PPAR delta; Structure-Activity Relationship; Thiazoles; X-Ray Microtomography

2021
Discovery of the first-in-class dual PPARδ/γ partial agonist for the treatment of metabolic syndrome.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Animals; Diabetes Mellitus, Experimental; Diet, High-Fat; Dose-Response Relationship, Drug; Drug Discovery; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Molecular Structure; Organic Chemicals; PPAR delta; PPAR gamma; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship

2021
Discovery of new and highly effective quadruple FFA1 and PPARα/γ/δ agonists as potential anti-fatty liver agents.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Animals; Chenodeoxycholic Acid; Drug Discovery; Gene Expression Regulation; Humans; Hypoglycemic Agents; Liver Cirrhosis; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Models, Molecular; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Protein Binding; Receptors, G-Protein-Coupled; Structure-Activity Relationship

2022
Design, synthesis, and biological evaluation of novel dual FFA1 and PPARδ agonists possessing phenoxyacetic acid scaffold.
    Bioorganic & medicinal chemistry, 2022, 02-15, Volume: 56

    Topics: Acetates; Animals; Dose-Response Relationship, Drug; Drug Design; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Molecular Structure; PPAR delta; Receptors, G-Protein-Coupled; Structure-Activity Relationship

2022
Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases.
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: 3T3-L1 Cells; Anacardic Acids; Anacardium; Animals; Drug Design; Gene Expression; HEK293 Cells; Humans; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Nuts; PPAR alpha; PPAR delta; PPAR gamma; Protein Domains; Zebrafish

2022
A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis.
    Journal of cellular physiology, 2008, Volume: 217, Issue:2

    Topics: Alkyl and Aryl Transferases; Animals; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Enzyme Induction; Glioma; Lipid Metabolism; Mice; Myelin Sheath; Oligodendroglia; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR gamma; PPAR-beta; Pyrimidines; Rats; Receptor Cross-Talk; RNA Interference; RNA, Small Interfering; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription, Genetic; Transfection

2008
Effect of synthetic ligands of PPAR α, β/δ, γ, RAR, RXR and LXR on the fatty acid composition of phospholipids in mice.
    Lipids, 2011, Volume: 46, Issue:11

    Topics: Acetyltransferases; Animals; Benzoates; Butyrates; Fatty Acid Elongases; Fatty Acids; Female; Gene Expression; Hydrocarbons, Fluorinated; Liver; Liver X Receptors; Mice; Mice, Inbred C57BL; Organic Chemicals; Orphan Nuclear Receptors; Peroxisome Proliferator-Activated Receptors; Phenylurea Compounds; Phospholipids; Receptors, Retinoic Acid; Rosiglitazone; Stearoyl-CoA Desaturase; Sulfonamides; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones

2011
Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Acyltransferases; Anilides; Animals; Blotting, Northern; Caco-2 Cells; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Computational Biology; HT29 Cells; Humans; Kidney Tubules, Proximal; Liver; Mice; Oxazoles; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sulfones; Thiazoles; Thiazolidinediones; Thiophenes; Tyrosine

2016