rosiglitazone has been researched along with gw 1929 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Blanchard, SG; Brackeen, MF; Brown, KK; Cobb, JE; Collins, JL; Harrington, WW; Hashim, MA; Henke, BR; Hull-Ryde, EA; Kaldor, I; Kliewer, SA; Lake, DH; Leesnitzer, LM; Lehmann, JM; Lenhard, JM; Miller, JF; Mook, RA; Noble, SA; Oliver, W; Orband-Miller, LA; Parks, DJ; Plunket, KD; Szewczyk, JR; Willson, TM | 1 |
| Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Gavande, N; Hanrahan, JR; Hibbs, DE; Kim, MS; Matin, A; Roubin, RH; Salam, NK; Yang, NX | 1 |
| Carta, G; Fayne, D; Lloyd, DG; Nevin, DK; Peters, MB | 1 |
| Altieri, F; Awaishima, H; Barendregt, A; Brunel, JM; Capelli, D; Grottesi, A; Heck, AJR; Itoh, T; Loiodice, F; Montanari, R; Nishikata, K; Paiardini, A; Pedone, E; Peiretti, F; Pirone, L; Pochetti, G; Yamamoto, K | 1 |
| Brown, KK; Görgün, CZ; Harrington, WW; Hotamisligil, GS; Kliewer, SA; Oliver, WR; Tong, Q; Uysal, KT; Way, JM; Willson, TM | 1 |
| Chatterjee, VK; Nugent, C; O'Rahilly, S; Prins, JB; Savage, D; Wentworth, JM; Whitehead, JP | 1 |
| Han, S; Rivera, HN; Roman, J | 1 |
| Coales, SJ; Griffin, PR; Hamuro, Y; Molnar, KS; Morrow, JA; Southern, MR; Tuske, SJ | 1 |
| Carluccio, MA; De Caterina, R; Distante, A; Massaro, M; Scoditti, E; Storelli, C | 1 |
| Akahira, J; Hui, XG; Ito, S; Kudo, M; Matsuda, K; Nakamura, Y; Noguchi, N; Okamoto, H; Rainey, WE; Sasano, H; Satoh, F; Sugawara, A; Uruno, A; Yoshikawa, T | 1 |
| Nakanishi, A; Tsukamoto, I | 1 |
1 review(s) available for rosiglitazone and gw 1929
| Article | Year |
|---|---|
The PPARs: from orphan receptors to drug discovery.
Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2000 |
12 other study(ies) available for rosiglitazone and gw 1929
| Article | Year |
|---|---|
N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents.
Topics: Administration, Oral; Aminopyridines; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Lipids; Male; Mice; Oxazoles; Propionates; Radioligand Assay; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Stereoisomerism; Structure-Activity Relationship; Transcription Factors; Transfection; Tyrosine | 1998 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.
Topics: Benzopyrans; Cell Line; Humans; PPAR alpha; PPAR gamma; Structure-Activity Relationship | 2009 |
Integrated virtual screening for the identification of novel and selective peroxisome proliferator-activated receptor (PPAR) scaffolds.
Topics: Benzamides; Binding, Competitive; Databases, Factual; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; HEK293 Cells; Humans; Models, Molecular; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Protein Conformation; Pyrazoles; Pyrrolidinones; Structure-Activity Relationship; Thiazoles; Thiobarbiturates | 2012 |
Insights into PPARγ Phosphorylation and Its Inhibition Mechanism.
Topics: Amino Acid Sequence; Biphenyl Compounds; Cyclin-Dependent Kinase 5; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Phenylpropionates; Phosphorylation; PPAR gamma; Protein Binding; Protein Conformation; Serine | 2020 |
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.
Topics: Adipocytes; Animals; Benzophenones; Down-Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2001 |
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.
Topics: 3T3 Cells; Adenoviridae; Adipocytes; Animals; Benzophenones; Cell Membrane; Drug Synergism; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Green Fluorescent Proteins; Hypoglycemic Agents; Insulin; Luminescent Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Mutation; Oxazoles; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Tyrosine | 2001 |
Peroxisome proliferator-activated receptor-gamma ligands inhibit alpha5 integrin gene transcription in non-small cell lung carcinoma cells.
Topics: Base Sequence; Benzophenones; Binding Sites; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Integrin alpha5; Ligands; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Tyrosine | 2005 |
Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators.
Topics: Amides; Amino Acid Sequence; Anilides; Benzophenones; Binding Sites; Deuterium Exchange Measurement; Indoles; Ligands; Mass Spectrometry; Models, Molecular; Pepsin A; Peptide Fragments; PPAR gamma; Protein Conformation; Protein Structure, Tertiary; Rosiglitazone; Sulfides; Thiazolidinediones; Tyrosine | 2006 |
PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.
Topics: Angiogenesis Inhibitors; Anilides; Benzhydryl Compounds; Benzophenones; Binding Sites; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Down-Regulation; Endothelial Cells; Epoxy Compounds; Gene Expression Regulation, Enzymologic; Humans; Neovascularization, Physiologic; Nitrobenzenes; PPAR gamma; Promoter Regions, Genetic; Protein Kinase C-alpha; Protein Transport; RNA Interference; RNA, Messenger; Rosiglitazone; Sulfonamides; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transfection; Tyrosine; Vascular Endothelial Growth Factor A | 2010 |
Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production.
Topics: Adrenal Cortex; Aldosterone; Benzophenones; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line; Cytochrome P-450 CYP11B2; Gene Expression; Gene Expression Regulation, Enzymologic; Humans; Ionomycin; Mutation; Pioglitazone; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Sulfonamides; Thiazolidinediones; Transcription, Genetic; Tyrosine; Zona Glomerulosa | 2011 |
n-3 polyunsaturated fatty acids stimulate osteoclastogenesis through PPARγ-mediated enhancement of c-Fos expression, and suppress osteoclastogenesis through PPARγ-dependent inhibition of NFkB activation.
Topics: Animals; Benzophenones; Bone Marrow Cells; Cells, Cultured; Cyclooxygenase 2; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Gene Expression Regulation; Male; Mesenchymal Stem Cells; NF-kappa B; Osteogenesis; PPAR gamma; Proto-Oncogene Proteins c-fos; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tyrosine | 2015 |