Page last updated: 2024-08-25

rosiglitazone and cyclosporine

rosiglitazone has been researched along with cyclosporine in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (40.74)	29.6817
2010's	15 (55.56)	24.3611
2020's	1 (3.70)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Norman, BH	1
Ergün, I; Keven, K	1
Ahn, KO; Choi, YH; Chung, BH; Ito, S; Kim, J; Li, C; Lim, SW; Sugawara, A; Sun, BK; Yang, CW; Yang, JH; Yoon, KH	1
Cheng, GY; Li, HJ; Li, JC; Liu, SZ; Liu, ZS; Yao, LN	1
Baldwin, D; Villanueva, G	1
Ahn, KO; Choi, BS; Ito, S; Kim, J; Kim, YS; Li, C; Lim, SW; Sugawara, A; Yang, CW; Yang, HJ	1
Dal Canton, A; De Amici, M; Gregorini, M; Guida, G; Guidetti, C; Libetta, C; Marasà, M; Rampino, T; Ranghino, A; Soccio, G	1
Chen, Y; Dallman, MJ; Lamb, JR; Liu, Y; Tam, PK; Thompson, PW; Tian, L; Yuan, Z	1
Bao, Y; Cai, B; Chen, S; Gao, J; Jiang, J; Le, K; Li, R; Liu, P; Zhang, F	1
Cho, JH; Kim, JW; Lee, SH; Park, HS; Sun, C; Yang, CW; Yang, JH; Yoon, KH	1
Gross, N	1
Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I	1
Dansako, H; Gu, W; Kato, N; Nishitsuji, H; Satoh, S; Shimotohno, K; Ueda, Y	1

Reviews

2 review(s) available for rosiglitazone and cyclosporine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies. Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20 Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Evaluation, Preclinical; Hepatocytes; Humans; Liver; Mitochondria, Liver; Pharmaceutical Preparations; Risk Assessment; Tissue Distribution	2020

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies.

Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20

Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Evaluation, Preclinical; Hepatocytes; Humans; Liver; Mitochondria, Liver; Pharmaceutical Preparations; Risk Assessment; Tissue Distribution

2020

Other Studies

25 other study(ies) available for rosiglitazone and cyclosporine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Short-term rosiglitazone treatment in renal transplant recipients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:7 Topics: Cyclosporine; Diabetes Mellitus; Drug Administration Schedule; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insulin Resistance; Kidney Transplantation; Rosiglitazone; Tacrolimus; Thiazolidinediones	2005
Rosiglitazone protects against cyclosporine-induced pancreatic and renal injury in rats. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, Volume: 5, Issue:8 Topics: Angiotensin II; Animals; Apoptosis; Cyclosporine; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Islets of Langerhans; Kidney; Osteopontin; Pancreatic Diseases; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sialoglycoproteins; Thiazolidinediones; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
[Protective effects of rosiglitazone on hepatotoxicity in hepatocytes cultured with cyclosporine A]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2005, Volume: 13, Issue:11 Topics: Animals; Cells, Cultured; Cyclosporine; Fibronectins; Hepatocytes; PPAR gamma; Protective Agents; Rats; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transforming Growth Factor beta1	2005
Rosiglitazone therapy of posttransplant diabetes mellitus. Transplantation, 2005, Nov-27, Volume: 80, Issue:10 Topics: Adult; Aged; Cyclosporine; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Insulin; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Organ Transplantation; PPAR gamma; Prospective Studies; Rosiglitazone; Tacrolimus; Thiazolidinediones	2005
Induction of PPAR gamma mRNA and protein expression by rosiglitazone in chronic cyclosporine nephropathy in the rat. Yonsei medical journal, 2007, Apr-30, Volume: 48, Issue:2 Topics: Animals; Cyclosporine; Disease Models, Animal; Gene Expression Regulation; Kidney Diseases; Male; PPAR gamma; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic	2007
Activation of PPARgamma enhances in vitro the immunosuppressive effect of cyclosporine on T lymphocytes. Transplant immunology, 2007, Volume: 18, Issue:1 Topics: Cell Cycle; Cells, Cultured; Cyclosporine; Humans; Immunosuppressive Agents; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Lymphocyte Activation; PPAR gamma; Rosiglitazone; T-Lymphocytes; Thiazolidinediones	2007
Rosiglitazone suppresses cyclosporin-induced chronic transplant dysfunction and prolongs survival of rat cardiac allografts. Transplantation, 2007, Jun-27, Volume: 83, Issue:12 Topics: Animals; Cyclosporine; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Models, Animal; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Transforming Growth Factor beta; Rosiglitazone; Thiazolidinediones; Transforming Growth Factor beta1; Transplantation, Homologous; Vasodilator Agents	2007
Activation of peroxisome proliferator-activated receptor gamma inhibits endothelin-1-induced cardiac hypertrophy via the calcineurin/NFAT signaling pathway. Molecular and cellular biochemistry, 2008, Volume: 317, Issue:1-2 Topics: Animals; Animals, Newborn; Calcineurin; Cardiomegaly; Cell Nucleus; Cell Size; Cyclosporine; Endothelin-1; Myocytes, Cardiac; NFATC Transcription Factors; PPAR gamma; Protein Biosynthesis; Protein Transport; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Surface Properties; Thiazolidinediones	2008
Rosiglitazone protects the pancreatic beta-cell death induced by cyclosporine A. Biochemical and biophysical research communications, 2009, Dec-18, Volume: 390, Issue:3 Topics: Animals; Cyclosporine; Cytoprotection; Diabetes Mellitus; Glucose Tolerance Test; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Insulin-Secreting Cells; Male; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Transplantation	2009
The COPD Pipeline XXI. COPD, 2013, Volume: 10, Issue:2 Topics: Acetylcysteine; Clinical Trials as Topic; Cyclosporine; Drug Discovery; Humans; Orphan Drug Production; Pulmonary Disease, Chronic Obstructive; Research Design; Research Report; Rosiglitazone; Thiazolidinediones	2013
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:6 Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidney; Kidney Diseases; Male; NAD; NADP; PPAR gamma; Prostaglandin D2; Protective Agents; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Urea; Uric Acid	2014
A new hepatoma cell line exhibiting high susceptibility to hepatitis B virus infection. Biochemical and biophysical research communications, 2019, 07-12, Volume: 515, Issue:1 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Host-Pathogen Interactions; Humans; Liver Neoplasms; Organic Anion Transporters, Sodium-Dependent; Rosiglitazone; Symporters; Virus Internalization	2019