rosiglitazone has been researched along with 15-deoxy-delta(12,14)-prostaglandin j2 in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (18.52) | 18.2507 |
| 2000's | 37 (68.52) | 29.6817 |
| 2010's | 7 (12.96) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chao, YS; Chern, JH; Kang, IJ; Lee, SJ; Lee, YZ; Wu, SH; Yang, CW | 1 |
| Brun, RP; Chen, J; Evans, RM; Forman, BM; Spiegelman, BM; Tontonoz, P | 1 |
| Kliewer, SA; Lehmann, JM; Lenhard, JM; Morris, DC; Patel, I; Willson, TM | 1 |
| Adams, M; Chatterjee, VK; Digby, JE; Holder, JC; Lazar, MA; Montague, CT; O'Rahilly, S; Prins, JB; Sanders, L; Sewter, CP; Smith, SA | 1 |
| Franciosa, MD; Greenberg, AS; Lien, P; Souza, SC; Yamamoto, MT | 1 |
| Alvarez, JG; Evans, RM; Nagy, L; Thomazy, VA; Tontonoz, P | 1 |
| Greenberg, AS; Rosenbaum, SE | 1 |
| Gerritsen, ME; Kowalski, J; Xin, X; Yang, S | 1 |
| Fleck, E; Goetze, S; Gotlibowski, T; Hsueh, WA; Kawano, H; Law, RE; Xi, XP | 1 |
| Burris, TP; Demarest, KT; Pelton, PD; Zhou, L | 1 |
| Bailey, ST; Flanigan, A; Jiang, W; Keilbaugh, SA; Lazar, MA; Murthy, S; Rangwala, SM; Su, CG; Wen, X; Wu, GD | 1 |
| Kalus, AM; Rubin, GL; Simpson, ER; Zhao, Y | 1 |
| Anania, FA; Miyahara, T; Motomura, K; Rippe, R; Schrum, L; Tsukamoto, H; Willson, TM; Xiong, S; Yee, HF | 1 |
| Angeli, V; Capron, M; Chinetti, G; Delerive, P; Faveeuw, C; Fontaine, J; Fougeray, S; Gosset, P; Maliszewski, C; Moser, M; Staels, B; Trottein, F | 1 |
| Person, EC; Scanlan, TS; Taylor, RN; Waite, LL | 1 |
| Bond, R; Cook, J; Gilkeson, G; Guyton, K; Halushka, P; Reilly, C | 1 |
| Berry, E; Gilmour, R; Helliwell, R; Keelan, J; Marvin, K; Mitchell, M; Nijmeijer, B; Sato, T | 1 |
| Dransfield, I; Farrow, SN; Haslett, C; Murray, J; Rossi, AG; Ward, C | 1 |
| Chatterjee, PK; Cuzzocrea, S; Hattori, Y; McDonald, MC; Mota-Filipe, H; Pisano, B; Thiemermann, C; Wayman, NS | 1 |
| Füzesi, L; Krüger, U; Middel, P; Mössner, R; Neumann, C; Reich, K; Schinner, S; Schulz, U | 1 |
| Armoni, M; Bar-Yoseph, F; Chen, H; Harel, C; Karnieli, E; Kritz, N; Quon, MJ | 1 |
| Delouis, C; Evain-Brion, D; Fournier, T; Hermouet, A; Pavan, L; Tarrade, A; Thérond, P; Titeux, M; Vidaud, M | 1 |
| Burgermeister, E; Liscovitch, M; Tencer, L | 1 |
| Chao, VA; Pritts, EA; Sohn, SH; Taylor, RN; Waite, LL; Zhao, D | 1 |
| Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Di Rosa, M; Dugo, L; Genovese, T; Ianaro, A; Patel, NS; Pisano, B; Thiemermann, C | 1 |
| Alemany, S; Caivano, M; Cohen, P; Rodriguez, C | 1 |
| Kumar, AP; Piedrafita, FJ; Reynolds, WF | 1 |
| Bai, AH; Chan, FK; Chan, KK; Chan, MW; Chan, VY; Fu, YG; Leung, WK; Sung, JJ; To, KF; Wu, JR; Yu, J | 1 |
| Andreeff, M; Chism, D; Collins, SJ; Elstner, E; Hu, W; Koeffler, HP; Konopleva, M; Kornblau, SM; McQueen, TJ; Schober, WD; Sudarikov, A; Tsao, T; Wang, RY; Younes, A | 1 |
| Caputi, AP; Catalano, P; Crimi, N; Cuzzocrea, S; Di Paola, R; Genovese, T; Mastruzzo, C; Mazzon, E; Sortino, M; Thiemermann, C; Vancheri, C | 1 |
| Bianchi, A; Boyault, S; Francois, M; Jouzeau, JY; Koufany, M; Moulin, D; Netter, P; Sebillaud, S; Terlain, B | 1 |
| Ackerman, WE; Kniss, DA; Rovin, BH; Zhang, XL | 1 |
| Allred, CD; Kilgore, MW | 1 |
| Artwohl, M; Baumgartner-Parzer, SM; Freudenthaler, A; Fürnsinn, C; Hölzenbein, T; Huttary, N; Waldhäusl, WK | 1 |
| Boscá, L; Cárdenas, A; Castillo, J; Dávalos, A; Hurtado, O; Lizasoain, I; Lorenzo, P; Moro, MA; Pereira, MP; Serena, J; Vivancos, J | 1 |
| Becchi, M; Boutin, JA; Cozzone, D; D'Orazio, D; Ferry, G; Géloën, A; Guichardant, M; Lagarde, M; Nosjean, O; Soares, AF | 1 |
| Bianchi, A; Galteau, MM; Jouzeau, JY; Koufany, M; Moulin, D; Netter, P; Sebillaud, S; Terlain, B | 1 |
| Jang, KY; Jang, YB; Kang, KP; Kim, DH; Kim, W; Lee, JE; Lee, S; Moon, SO; Park, SK; Sung, MJ | 1 |
| Hiramatsu, Y; Masumoto, A; Masuyama, H; Suwaki, N; Takamoto, N | 1 |
| Horinaka, M; Kouhara, J; Nakata, S; Sakai, T; Shiraishi, T; Wakada, M; Yoshida, T | 1 |
| Elstner, E; Eucker, J; Heider, U; Jakob, C; Kaiser, M; Krebbel, H; Sezer, O; Sterz, J; Zang, C; Zavrski, I | 1 |
| Blero, D; Bruyns, C; Caspers, L; De Graef, C; Driessens, G; Dulku, S; Gonzalez, NS; Willermain, F | 1 |
| Blay, J; Lowthers, EL; Richard, CL | 1 |
| Caito, S; Edirisinghe, I; Kode, A; Phipps, RP; Rahman, I; Rajendrasozhan, S; Yang, SR | 1 |
| Gao, DF; Hao, GH; Niu, XL; Wang, NP; Wei, J | 1 |
| Aeed, H; Bruck, R; Halpern, Z; Pines, M; Weiss, S; Zvibel, I | 1 |
| Ferguson, HE; Garcia-Bates, TM; Huxlin, KR; Kulkarni, A; Lehmann, GM; Phipps, RP; Sime, PJ; Thatcher, TH | 1 |
| Garzón, B; Pérez-Sala, D; Zorrilla, S | 1 |
| Choi, GS; Jou, I; Kim, SH; Park, HS; Park, SM; Ye, YM | 1 |
| Armani, C; Bardelli, C; Breschi, MC; Brunelleschi, S; Carmazzi, Y; Celi, A; Cordazzo, C; Neri, T; Paggiaro, P; Pegoli, A | 1 |
| Choi, YJ; Ham, SA; Hwang, JS; Kang, ES; Kang, KR; Kim, GH; Lee, JH; Lee, WJ; Paek, KS; Park, MH; Seo, HG; Yoo, T | 1 |
| Casali, CI; Faggionato, D; Gómez, EM; Tome, MC; Weber, K | 1 |
| Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I | 1 |
| Huxlin, KR; Jeon, KI; Phipps, RP; Sime, PJ | 1 |
54 other study(ies) available for rosiglitazone and 15-deoxy-delta(12,14)-prostaglandin j2
| Article | Year |
|---|---|
Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma.
Topics: Alkanesulfonates; Animals; Anti-Inflammatory Agents; Cell Line; Chemistry, Pharmaceutical; Drug Design; Enzyme Activation; Esters; Inhibitory Concentration 50; Mice; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase Type II; PPAR gamma; Sulfonic Acids; Transcriptional Activation | 2008 |
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma.
Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Carrier Proteins; Cell Differentiation; Complement Factor D; DNA-Binding Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fibroblasts; Hypoglycemic Agents; Ligands; Mice; Molecular Sequence Data; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Pioglitazone; Prostaglandin D2; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Serine Endopeptidases; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 1995 |
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.
Topics: Adipocytes; Animals; Binding, Competitive; Cell Differentiation; Cells, Cultured; Fibroblasts; Hypoglycemic Agents; Ligands; Mice; Microbodies; Prostaglandin D2; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation | 1995 |
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.
Topics: Adipocytes; Animals; Cell Differentiation; Cells, Cultured; Chromans; Humans; Mice; Microbodies; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Stem Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Troglitazone | 1997 |
BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones.
Topics: 3T3 Cells; Adipocytes; Animals; Carrier Proteins; Fatty Acids, Nonesterified; Glycerol; Hypoglycemic Agents; Insulin Resistance; Lipolysis; Mice; Perilipin-1; Phosphoproteins; Prostaglandin D2; Rosiglitazone; Sterol Esterase; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha | 1998 |
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL.
Topics: Alitretinoin; Animals; Arteriosclerosis; CD36 Antigens; Cell Differentiation; Dimerization; Foam Cells; HL-60 Cells; Humans; Ligands; Lipoproteins, LDL; Macrophages; Membrane Proteins; Mice; Mice, Transgenic; Monocytes; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Retinoic Acid; Receptors, Scavenger; Retinoid X Receptors; Rosiglitazone; Scavenger Receptors, Class B; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Tretinoin | 1998 |
The short- and long-term effects of tumor necrosis factor-alpha and BRL 49653 on peroxisome proliferator-activated receptor (PPAR)gamma2 gene expression and other adipocyte genes.
Topics: Adipocytes; Animals; Carrier Proteins; Cell Differentiation; Down-Regulation; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Gene Expression Regulation; Hypoglycemic Agents; Mice; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Perilipin-1; Phosphoproteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Sterol Esterase; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1998 |
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Cornea; Eicosanoids; Endothelium, Vascular; Gene Expression Regulation; Humans; Ligands; Neovascularization, Physiologic; Prostaglandin D2; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1999 |
PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cells, Cultured; Chemotactic Factors; Chromans; Cycloheximide; Dactinomycin; Enzyme Activation; Insulin-Like Growth Factor I; Ligands; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Prostaglandin D2; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thrombin; Transcription Factors; Troglitazone | 1999 |
PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes.
Topics: Adipocytes; Carrier Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Chromans; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Gene Expression; Humans; Kinetics; Monocytes; Myelin P2 Protein; Neoplasm Proteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Suppressor Proteins | 1999 |
A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response.
Topics: Animals; Caco-2 Cells; Colitis; Cytokines; DNA-Binding Proteins; Epithelium; Gene Expression; HT29 Cells; Humans; I-kappa B Proteins; Inflammation; Inflammatory Bowel Diseases; Interleukin-8; Ligands; Mice; Microbodies; NF-kappa B; NF-KappaB Inhibitor alpha; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1999 |
Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: possible implications for breast cancer therapy.
Topics: Adipose Tissue; Animals; Aromatase; Aromatase Inhibitors; Binding, Competitive; Breast; Breast Neoplasms; Cell Line; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Estrogens; Female; Gene Expression Regulation, Enzymologic; Humans; Ligands; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone | 2000 |
Peroxisome proliferator-activated receptors and hepatic stellate cell activation.
Topics: Animals; Cell Size; Cell Survival; Cells, Cultured; Collagen; DNA; Gene Expression Regulation; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Promoter Regions, Genetic; Prostaglandin D2; Protein Binding; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha | 2000 |
Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells.
Topics: Animals; Antigens, CD; CD40 Antigens; Cell Differentiation; Dendritic Cells; Dimethyl Sulfoxide; Interferon-gamma; Interleukin-12; Interleukins; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors | 2000 |
Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12-14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo.
Topics: Hot Temperature; Immunologic Factors; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Serum Albumin; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured | 2001 |
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Topics: Animals; Cyclopentanes; DNA-Binding Proteins; Enzyme Activation; Epoprostenol; I-kappa B Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Prostaglandin D2; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Thromboxane B2; Transcription Factors; Tumor Necrosis Factor-alpha | 2001 |
15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells.
Topics: Amino Acid Chloromethyl Ketones; Amnion; Apoptosis; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Enzyme Activation; Humans; Hypoglycemic Agents; Immunologic Factors; Ligands; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors | 2001 |
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism.
Topics: Apoptosis; Binding Sites; Caspases; Cell Death; Cells, Cultured; Dinoprost; DNA-Binding Proteins; Enzyme Activation; Eosinophils; Granulocytes; Humans; Hydrolysis; I-kappa B Proteins; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Peroxisomes; Prostaglandin D2; Protein Biosynthesis; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Prostaglandin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
Topics: Adult; Animals; Cardiotonic Agents; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chemokine CCL2; Clofibrate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ligands; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Pioglitazone; Prostaglandin D2; Prostaglandins A; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Chromans; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gene Expression Regulation, Neoplastic; Humans; Immunologic Factors; Melanoma; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Skin Neoplasms; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2002 |
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect.
Topics: Adipocytes; Animals; CHO Cells; Cricetinae; Dimerization; Fibroblasts; Gene Expression Regulation; Genetic Complementation Test; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Immunologic Factors; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Promoter Regions, Genetic; Prostaglandin D2; Protein Structure, Tertiary; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Rosiglitazone; Suppression, Genetic; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic | 2003 |
Human invasive trophoblasts transformed with simian virus 40 provide a new tool to study the role of PPARgamma in cell invasion process.
Topics: Antigens, Polyomavirus Transforming; Cell Division; Cell Transformation, Viral; Cells, Cultured; DNA Primers; Dose-Response Relationship, Drug; Humans; Immunoblotting; Nuclear Proteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Simian virus 40; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Trophoblasts | 2003 |
Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.
Topics: Adenocarcinoma; Antigens, Differentiation; Antigens, Neoplasm; Breast Neoplasms; Caveolin 1; Caveolin 2; Caveolins; Cell Differentiation; Cell Line; Chromans; Colonic Neoplasms; Dimerization; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Kidney; Ligands; Macromolecular Substances; Membrane Microdomains; Neoplasm Proteins; Phenotype; Phenylacetates; Prostaglandin D2; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; RNA, Neoplasm; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Tumor Cells, Cultured | 2003 |
Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element.
Topics: Base Sequence; Cells, Cultured; Chemokine CCL5; Endometriosis; Female; Humans; Ligands; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Response Elements; Rosiglitazone; Stromal Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection | 2003 |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Epoxy Compounds; Immunologic Factors; Intercellular Adhesion Molecule-1; Interleukin-1; Intestinal Mucosa; Intestines; Ligands; Male; Malondialdehyde; Peroxidase; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Reperfusion Injury; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine; Vasodilator Agents | 2003 |
15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinogens; Cell Division; Cell Line; Enzyme Activation; Enzyme Inhibitors; Fibrinolytic Agents; Gene Expression Regulation, Enzymologic; Indoles; Ligands; Lipopolysaccharides; Macrophages; Maleimides; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Precipitin Tests; Prostaglandin D2; Protein Isoforms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; RNA, Messenger; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazolidinediones; Time Factors | 2003 |
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism.
Topics: Alu Elements; Animals; Arteriosclerosis; Binding Sites; Bone Marrow Cells; Cells, Cultured; Estradiol; Estrogen Receptor alpha; Estrogens; Gene Expression Regulation, Enzymologic; Genotype; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Peroxidase; Polymorphism, Genetic; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, LDL; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription Factors | 2004 |
Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cyclooxygenase 2; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Ligands; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Nuclear Receptor Coactivators; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rosiglitazone; Stomach Neoplasms; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured | 2004 |
Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias.
Topics: Agar; Apoptosis; Blotting, Western; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Dimerization; Fibrinolytic Agents; Flow Cytometry; HL-60 Cells; Humans; Imidazoles; Immunologic Factors; Jurkat Cells; Leukemia; Ligands; Oleanolic Acid; Phagocytosis; Plasmids; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Transcriptional Activation; Transfection; U937 Cells | 2004 |
Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Biopsy; Bleomycin; Epoxy Compounds; Immunoenzyme Techniques; Instillation, Drug; Male; Mice; Nitric Oxide Synthase; Peroxidase; Poly(ADP-ribose) Polymerases; Prostaglandin D2; Pulmonary Fibrosis; Random Allocation; Rosiglitazone; Thiazolidinediones; Tyrosine; Weight Loss | 2005 |
Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism.
Topics: Animals; Cell Culture Techniques; Fibroblasts; Immunologic Factors; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Knee Joint; Male; Models, Animal; Peroxisome Proliferator-Activated Receptors; PPAR delta; PPAR gamma; PPAR-beta; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Interleukin-1; Rosiglitazone; Sialoglycoproteins; Synovial Membrane; Thiazolidinediones | 2005 |
Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells.
Topics: Amnion; Cells, Cultured; Chromans; Cyclooxygenase 2; Epithelial Cells; Gene Expression Regulation; Humans; Membrane Proteins; NF-kappa B; PPAR gamma; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha | 2005 |
Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.
Topics: Alitretinoin; Anilides; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; HT29 Cells; Humans; Ligands; Lung Neoplasms; PPAR gamma; Prostaglandin D2; Retinoid X Receptor alpha; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transfection; Tretinoin | 2005 |
Thiazolidinediones inhibit apoptosis and heat shock protein 60 expression in human vascular endothelial cells.
Topics: Aorta; Apoptosis; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Chaperonin 60; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Endothelium, Vascular; Enzyme Activation; Humans; Hypoglycemic Agents; Ligands; Microscopy, Phase-Contrast; Mitochondria; Pioglitazone; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Rosiglitazone; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tumor Necrosis Factor-alpha; von Willebrand Factor | 2005 |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Disease Models, Animal; Drug Administration Schedule; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; NF-kappa B; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oligonucleotide Array Sequence Analysis; PPAR gamma; Prostaglandin D2; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Time Factors | 2006 |
Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma.
Topics: Adipocytes; Hypoglycemic Agents; Ligands; PPAR gamma; Prostaglandin D2; Protein Binding; Rosiglitazone; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazolidinediones; Time Factors | 2005 |
Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostagl
Topics: Animals; Cell Membrane; Cell Survival; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Drug Combinations; Gene Expression; Immunologic Factors; Interleukin-1; Intramolecular Oxidoreductases; Male; PPAR gamma; Prostaglandin D2; Prostaglandin-E Synthases; Rats; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transfection | 2005 |
Rosiglitazone ameliorates cisplatin-induced renal injury in mice.
Topics: Anilides; Animals; Apoptosis; C-Peptide; Cell Line; Chromans; Cisplatin; Drug Evaluation, Preclinical; Glioma; Humans; Hypoglycemic Agents; Inflammation; Insulin; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Tubules, Proximal; Macrophages; Male; Mice; Mice, Inbred C57BL; Monocytes; PPAR gamma; Prostaglandin D2; Protein Transport; Rosiglitazone; Thiazolidinediones; Transcription Factor RelA; Troglitazone; Tumor Necrosis Factor-alpha | 2006 |
Expression and potential role of peroxisome proliferator-activated receptor gamma in the placenta of diabetic pregnancy.
Topics: Animals; Blood Glucose; Cell Line, Tumor; Cell Proliferation; Choriocarcinoma; Chorionic Gonadotropin; Diabetes Mellitus, Experimental; Female; Fibrinolytic Agents; Humans; Immunologic Factors; Mice; Mice, Inbred ICR; Placenta; PPAR gamma; Pregnancy; Pregnancy in Diabetics; Prostaglandin D2; Rosiglitazone; Thiazolidinediones; Trophoblasts; Vascular Endothelial Growth Factor A | 2007 |
15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Gene Expression; Humans; Jurkat Cells; Membrane Glycoproteins; Neoplasms; Pioglitazone; PPAR gamma; Prostaglandin D2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA Stability; RNA, Messenger; RNA, Small Interfering; Rosiglitazone; Thiazolidinediones; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2006 |
Peroxisome proliferator-activated receptor-gamma ligands inhibit proliferation and induce apoptosis in mantle cell lymphoma.
Topics: Annexin A5; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Humans; Ligands; Lymphoma, Mantle-Cell; Pioglitazone; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones | 2006 |
15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism.
Topics: Cell Line; Cells, Cultured; Chromans; Coculture Techniques; Dinoprost; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Histocompatibility Antigens Class I; HLA-D Antigens; Humans; Immunologic Factors; Intercellular Adhesion Molecule-1; Interferon Regulatory Factor-1; Interferon Regulatory Factor-2; Interferon-gamma; Nuclear Proteins; Phosphorylation; Pigment Epithelium of Eye; PPAR gamma; Prostaglandin D2; Rosiglitazone; STAT Transcription Factors; T-Lymphocytes; Thiazolidinediones; Trans-Activators; Troglitazone | 2006 |
15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways.
Topics: Animals; Carcinoma; Cell Line, Tumor; Cyclopentanes; Down-Regulation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; NF-kappa B; PPAR gamma; Prostaglandin D2; Receptors, CXCR4; Rosiglitazone; Thiazolidinediones; Time Factors | 2007 |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages.
Topics: Cell Line; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Hypoglycemic Agents; Immunologic Factors; Interleukin-8; Macrophages; Monocytes; PPAR gamma; Prostaglandin D2; Protein Processing, Post-Translational; Rosiglitazone; Smoke; Smoking; Thiazolidinediones | 2008 |
Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts.
Topics: Angiotensin II; Animals; Cell Proliferation; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblasts; Fibrosis; Gene Expression Regulation; Male; Myocardium; Plasminogen Activator Inhibitor 1; PPAR gamma; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta1 | 2008 |
Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor.
Topics: Alitretinoin; Animals; Cell Proliferation; Collagen Type I; Cytokines; Drug Synergism; Hepatic Stellate Cells; Liver Cirrhosis, Experimental; Male; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Retinoid X Receptors; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Thioacetamide; Tretinoin | 2009 |
Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
Topics: Acetylation; Actins; Base Sequence; Cell Differentiation; Cells, Cultured; DNA Primers; Fibroblasts; Humans; Ligands; Lung; Oleanolic Acid; p300-CBP Transcription Factors; PPAR gamma; Prostaglandin D2; Pulmonary Fibrosis; Rosiglitazone; Signal Transduction; Smad Proteins; Thiazolidinediones; Transcription Factor AP-1; Transforming Growth Factor beta | 2009 |
Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization.
Topics: Anilino Naphthalenesulfonates; Binding, Competitive; Fluorescence Polarization; Fluorescent Dyes; Humans; Ligands; PPAR gamma; Prostaglandin D2; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Rosiglitazone; Thermodynamics; Thiazolidinediones | 2010 |
Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma.
Topics: Active Transport, Cell Nucleus; Adult; Apoferritins; Asthma; Catalase; Cell Line; Cell Nucleus; Chemical Industry; Female; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase-1; Humans; Hypoglycemic Agents; Immunologic Factors; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase Kinases; NF-E2-Related Factor 2; Occupational Exposure; Peroxiredoxins; PPAR gamma; Prostaglandin D2; Respiratory Mucosa; Rosiglitazone; Thiazolidinediones; Thioredoxins; Toluene 2,4-Diisocyanate; Transferrin | 2010 |
Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles.
Topics: Anilides; Bronchi; Calcimycin; Cell Line; Cell-Derived Microparticles; Cells, Cultured; Chemokine CCL2; Humans; Interleukin-8; Ionophores; Monocytes; NF-kappa B; Pneumonia; PPAR gamma; Prostaglandin D2; Rosiglitazone; Thiazolidinediones; Up-Regulation | 2011 |
15-Deoxy-Δ(12,14)-prostaglandin J2 prevents oxidative injury by upregulating the expression of aldose reductase in vascular smooth muscle cells.
Topics: Aldehyde Reductase; Animals; Antioxidant Response Elements; Base Sequence; Cells, Cultured; Chromans; Enzyme Induction; Glucose Oxidase; Male; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rosiglitazone; Signal Transduction; Thiazolidinediones; Troglitazone; Up-Regulation | 2014 |
Coordinate regulation between the nuclear receptor peroxisome proliferator-activated receptor-γ and cyclooxygenase-2 in renal epithelial cells.
Topics: Anilides; Animals; Base Sequence; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; DNA Primers; Dogs; Epithelial Cells; Kidney; Phosphorylation; PPAR gamma; Prostaglandin D2; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Sodium Chloride; Thiazolidinediones | 2014 |
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidney; Kidney Diseases; Male; NAD; NADP; PPAR gamma; Prostaglandin D2; Protective Agents; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Urea; Uric Acid | 2014 |
Antifibrotic Actions of Peroxisome Proliferator-Activated Receptor γ Ligands in Corneal Fibroblasts Are Mediated by β-Catenin-Regulated Pathways.
Topics: Actins; Animals; beta Catenin; Cats; Chromans; Collagen Type I; Cornea; Fibroblasts; Fibronectins; Fibrosis; Glycogen Synthase Kinase 3 beta; Lithium Chloride; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR gamma; Prostaglandin D2; Pyrvinium Compounds; Receptors, Transforming Growth Factor beta; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta1; Troglitazone | 2017 |