Page last updated: 2024-09-05

roseoflavin and riboflavin

roseoflavin has been researched along with riboflavin in 45 studies

Compound Research Comparison

Studies (roseoflavin)	Trials (roseoflavin)	Recent Studies (post-2010) (roseoflavin)	Studies (riboflavin)	Trials (riboflavin)	Recent Studies (post-2010) (riboflavin)
48	0	29	9,345	389	3,015

Protein Interaction Comparison

Protein	Taxonomy	roseoflavin (IC50)	riboflavin (IC50)
Thiosulfate sulfurtransferase	Homo sapiens (human)		8.8

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (13.33)	18.7374
1990's	1 (2.22)	18.2507
2000's	8 (17.78)	29.6817
2010's	23 (51.11)	24.3611
2020's	7 (15.56)	2.80

Authors

Authors	Studies
Glazunov, EA; Kukanova, AIa; Stepanov, AI; Zhdanov, VG	1
Horváth, I; Otani, S; Szeberényi, S; Tihanyi, K	1
Juri, N; Kasai, S; Kubo, Y; Kusunose, M; Matsui, K; Otani, S	1
Gressel, J; Horwitz, BA; Malkin, S	1
Kukanova, AIa; Stepanov, AI; Zhdanov, VG	1
Kasai, S; Matsui, K; Otani, S	2
Aver'yanov, AA; Lapikova, VP; Nikolaev, ON; Stepanov, AI	1
Cooke, G; Legrand, YM; Rotello, VM	1
Burgess, C; Hugenholtz, J; O'connell-Motherway, M; Sybesma, W; van Sinderen, D	1
Burgess, CM; Duurkens, RH; Geertsma, ER; Poolman, B; Slotboom, DJ; van Sinderen, D	1
Grill, S; Mack, M; Schilling, O; Stolz, J; Stülke, J; Vogl, C	1
Busenbender, S; Grill, S; Köhler, U; Mack, M; Pfeiffer, M	1
Hegemann, P; Mathes, T; Stolz, J; Vogl, C	1
Hegemann, P; Mathes, T; Penzkofer, A; Zirak, P	1
Hegemann, P; Mathes, T; Penzkofer, A; Tyagi, A	1
Jankowitsch, F; Kalinowski, J; Kellner, R; Kühm, C; Macheroux, P; Mack, M; Pelzer, S	1
Barile, M; Carmona, EC; Gärtner, W; Lux, A; Mack, M; Mansurova, M; Nakanishi, S; Pedrolli, DB	1
Hemberger, S; Lehmann, M; Mack, M; Pedrolli, DB; Stolz, J; Vogl, C	1
Breaker, R; Ester, M; Mack, M; Matern, A; Pedrolli, DB; Siedler, K; Wang, J	1
Blom, J; Gust, B; Jankowitsch, F; Kalinowski, J; Mack, M; Pelzer, S; Rückert, C; Schwarz, J; Szczepanowski, R	1
Hashimoto, M; Hobl, B; Langer, S; Mack, M; Mathes, T	1
Mack, M; Pedrolli, DB	1
Arena, MP; Capozzi, V; Dueñas, MT; Fiocco, D; López, P; Russo, P; Spadaccino, G; Spano, G	1
Bacher, A; Fischer, M; Gräwert, T; Haase, I; Illarionov, B	1
Jankowitsch, F; Langer, S; Mack, M; Nakanishi, S; Pedrolli, DB; Schwarz, J	1
Karasulu, B; Thiel, W	1
Gruber, K; Jankowitsch, F; Macheroux, P; Mack, M; Tongsook, C; Uhl, MK	1
Jankowitsch, F; Konjik, V; Mack, M; Sandhoff, R; Schwarz, J	1
Abdelwahed, SH; Begley, TP; Chanani, PK; Jhulki, I	1
Großhennig, S; Johansson, J; Mack, M; Matern, A; Pedrolli, D	1
Balcazar, DE; Bonomi, HR; Carrillo, C; Goldbaum, FA; Pereira, CA; Romano, PS; Vanrell, MC	1
Barbieri, CM; Flattery, A; Galgoci, AM; Gill, C; Howe, JA; Mack, M; Malinverni, JC; Mann, PA; Mayhood, T; McCurry, MD; Murgolo, N; Roemer, T; Sher, X; Villafania, A; Wang, H; Xiao, L	1
Ignatov, D; Johansson, J; Krajewski, SS	1
Bourdeaux, F; Busche, T; Grininger, M; Kalinowski, J; Ludwig, P; Mack, M; Sévin, DC	1
Dmytruk, KV; Fedorovych, DV; Kordiaka, R; Sybirny, AA; Tsyrulnyk, AO	1
Bourdeaux, F; Essen, LO; Grininger, M; Ludwig, P; Mack, M; Paithankar, K; Sander, B	1
Mack, M; Mora-Lugo, R; Stegmüller, J	1
Busche, T; Dorjjugder, N; Kalinowski, J; Kißling, L; Mack, M; Schneider, C; Seibel, K	1
Kißling, L; Konjik, V; Mack, M; Schneider, C	1
Capozzi, V; De Simone, N; Del Solar, G; López, P; Mohedano, ML; Ruiz-Masó, JÁ; Russo, P; Spano, G	1
Mack, M; Schneider, C	1
Hemasa, AL; Mack, M; Saliba, KJ	1
Chaiyen, P; Charoenwongpaiboon, T; Klaewkla, M; Tongsook, C	1
Andreieva, YA; Chrzanowski, G; Dmytruk, KV; Dmytruk, OV; Fayura, LR; Fedorovych, DV; Marx, H; Mattanovich, D; Motyka, OI; Ruchala, J; Sibirny, AA; Tsyrulnyk, AO	1

Reviews

3 review(s) available for roseoflavin and riboflavin

Article	Year
Chemistry and biochemistry of 8-aminoflavins. Osaka city medical journal, 1997, Volume: 43, Issue:2 Topics: Absorption; Biochemistry; Flavins; Molecular Structure; Riboflavin; Ultraviolet Rays	1997
Recent advances in riboflavin biosynthesis. Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1146 Topics: Animals; Anti-Infective Agents; Biosynthetic Pathways; Brucella Vaccine; Fermentation; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Gene Expression Regulation; Humans; Multienzyme Complexes; Riboflavin; Riboflavin Synthase	2014
Natural riboflavin analogs. Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1146 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biological Products; Drug Resistance, Microbial; Enzyme Inhibitors; Flavins; Humans; Riboflavin	2014

Other Studies

42 other study(ies) available for roseoflavin and riboflavin

Article	Year
[Analgos of riboflavin, lumiflavin and alloxazine derivatives. II. Effect of roseoflavin on 6,7-dimethyl-8-ribityllumazine and riboflavin synthetase synthesis and growth of Bacillus subtilis]. Genetika, 1977, Volume: 13, Issue:3 Topics: Bacillus subtilis; Chemical Phenomena; Chemistry; Flavins; Mutation; Pteridines; Riboflavin; Riboflavin Synthase; Ribose; Species Specificity; Structure-Activity Relationship; Sugar Alcohols; Transferases	1977
Effect of roseoflavin on microsomal drug-metabolizing enzyme system. FEBS letters, 1979, Feb-01, Volume: 98, Issue:1 Topics: Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Female; Flavins; Hexobarbital; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Riboflavin; Sleep; Sugar Alcohols	1979
Formation of roseoflavin from 8-amino- and 8-methylamino-8-demethyl-D-riboflavin. Journal of biochemistry, 1987, Volume: 101, Issue:3 Topics: Chromatography, Thin Layer; Methionine; Riboflavin; Streptomyces	1987
Roseoflavin inhibition of photoconidiation in a Trichoderma riboflavin auxotroph: indirect evidence for flavin requirement for photoreactions. Photochemistry and photobiology, 1984, Volume: 40, Issue:6 Topics: Animals; Anti-Bacterial Agents; Mitosporic Fungi; Morphogenesis; Riboflavin; Trichoderma	1984
[Bacillus subtilis mutants resistant to roseoflavin]. Genetika, 1982, Volume: 18, Issue:2 Topics: Anti-Bacterial Agents; Bacillus subtilis; Drug Resistance, Microbial; Mutation; Operon; Riboflavin	1982
Isolation, chemical synthesis, and properties of roseoflavin. Methods in enzymology, 1980, Volume: 66 Topics: Chromatography, Thin Layer; Indicators and Reagents; Methods; Oxidation-Reduction; Riboflavin; Spectrophotometry; Streptomyces	1980
Active oxygen-associated control of rice blast disease by riboflavin and roseoflavin. Biochemistry. Biokhimiia, 2000, Volume: 65, Issue:11 Topics: Magnaporthe; Oryza; Plant Diseases; Riboflavin; Superoxides	2000
Model systems for flavoenzyme activity: an electrochemically tuneable model of roseoflavin. Chemical communications (Cambridge, England), 2004, May-07, Issue:9 Topics: Apoenzymes; Bacterial Proteins; Electrochemistry; Flavoproteins; Hydrogen Bonding; Molecular Structure; Oxidation-Reduction; Oxidoreductases; Riboflavin	2004
Riboflavin production in Lactococcus lactis: potential for in situ production of vitamin-enriched foods. Applied and environmental microbiology, 2004, Volume: 70, Issue:10 Topics: Base Sequence; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Fermentation; Food, Fortified; Gene Deletion; Gene Expression; Genes, Bacterial; Genetic Complementation Test; Genetic Engineering; Lactococcus lactis; Molecular Sequence Data; Mutation; Operon; Riboflavin	2004
The riboflavin transporter RibU in Lactococcus lactis: molecular characterization of gene expression and the transport mechanism. Journal of bacteriology, 2006, Volume: 188, Issue:8 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Artificial Gene Fusion; Bacterial Proteins; Base Sequence; beta-Galactosidase; Binding Sites; Blotting, Northern; DNA, Bacterial; Flavin Mononucleotide; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Reporter; Lactococcus lactis; Membrane Transport Proteins; Molecular Sequence Data; Promoter Regions, Genetic; Protein Structure, Tertiary; Regulatory Sequences, Nucleic Acid; Riboflavin; Sequence Alignment; Sequence Analysis, DNA	2006
Characterization of riboflavin (vitamin B2) transport proteins from Bacillus subtilis and Corynebacterium glutamicum. Journal of bacteriology, 2007, Volume: 189, Issue:20 Topics: Bacillus subtilis; Bacterial Proteins; Biological Transport; Corynebacterium glutamicum; Gene Deletion; Gene Expression Regulation, Bacterial; Membrane Transport Proteins; Riboflavin; Substrate Specificity; Uncoupling Agents	2007
The bifunctional flavokinase/flavin adenine dinucleotide synthetase from Streptomyces davawensis produces inactive flavin cofactors and is not involved in resistance to the antibiotic roseoflavin. Journal of bacteriology, 2008, Volume: 190, Issue:5 Topics: Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Chromatography, High Pressure Liquid; Drug Resistance, Bacterial; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Genetic Complementation Test; Kinetics; Models, Genetic; Molecular Structure; Nucleotidyltransferases; Phosphotransferases (Alcohol Group Acceptor); Riboflavin; Streptomyces	2008
In vivo generation of flavoproteins with modified cofactors. Journal of molecular biology, 2009, Feb-06, Volume: 385, Issue:5 Topics: Bacterial Proteins; Corynebacterium glutamicum; Escherichia coli; Flavoproteins; Mycobacterium tuberculosis; Photoreceptors, Microbial; Protein Binding; Riboflavin	2009
Absorption and emission spectroscopic characterization of BLUF protein Slr1694 from Synechocystis sp. PCC6803 with roseoflavin cofactor. Journal of photochemistry and photobiology. B, Biology, 2009, Nov-09, Volume: 97, Issue:2 Topics: Absorption; Bacterial Proteins; Hydrogen-Ion Concentration; Light; Photolysis; Riboflavin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Synechocystis	2009
Photophysical characterisation and photo-cycle dynamics of LOV1-His domain of phototropin from Chlamydomonas reinhardtii with roseoflavin monophosphate cofactor. Journal of photochemistry and photobiology. B, Biology, 2010, Oct-05, Volume: 101, Issue:1 Topics: Absorption; Chlamydomonas reinhardtii; Flavin Mononucleotide; Flavins; Hydrogen-Ion Concentration; Photolysis; Phototropins; Protein Structure, Tertiary; Riboflavin; Spectrometry, Fluorescence; Temperature	2010
A novel N,N-8-amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis. The Journal of biological chemistry, 2011, Nov-04, Volume: 286, Issue:44 Topics: Amino Acid Sequence; Catalysis; Escherichia coli; Kinetics; Ligands; Methyltransferases; Molecular Sequence Data; Multigene Family; Open Reading Frames; Protein Structure, Tertiary; Recombinant Fusion Proteins; Riboflavin; Sequence Homology, Amino Acid; Streptomyces; Tandem Mass Spectrometry	2011
The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from Streptomyces davawensis are metabolized by human flavokinase and human FAD synthetase. Biochemical pharmacology, 2011, Dec-15, Volume: 82, Issue:12 Topics: Anti-Bacterial Agents; Catalytic Domain; Dithionite; Escherichia coli; Gene Expression Regulation, Enzymologic; Humans; Models, Molecular; Molecular Structure; Nucleotidyltransferases; Phosphotransferases (Alcohol Group Acceptor); Pichia; Protein Conformation; Riboflavin; Streptomyces	2011
RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains. BMC biotechnology, 2011, Dec-02, Volume: 11 Topics: Bacillus subtilis; Bioreactors; Biotechnology; Blotting, Northern; Blotting, Western; Carbon Radioisotopes; Escherichia coli; Gene Transfer Techniques; Isopropyl Thiogalactoside; Membrane Transport Proteins; Plasmids; Riboflavin; Streptomyces	2011
A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis. Nucleic acids research, 2012, Sep-01, Volume: 40, Issue:17 Topics: Anti-Bacterial Agents; Aptamers, Nucleotide; Cytoplasm; Drug Resistance, Fungal; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Gene Expression Regulation, Fungal; Genome, Fungal; Ligands; Point Mutation; Protein Biosynthesis; Riboflavin; Riboflavin Synthase; Riboswitch; Streptomyces; Streptomyces coelicolor	2012
Genome sequence of the bacterium Streptomyces davawensis JCM 4913 and heterologous production of the unique antibiotic roseoflavin. Journal of bacteriology, 2012, Volume: 194, Issue:24 Topics: Anti-Bacterial Agents; Base Sequence; Genome, Bacterial; Multigene Family; Phylogeny; Plasmids; Riboflavin; Sequence Analysis, DNA; Streptomyces	2012
Flavoproteins are potential targets for the antibiotic roseoflavin in Escherichia coli. Journal of bacteriology, 2013, Volume: 195, Issue:18 Topics: Anti-Bacterial Agents; Bacillus subtilis; Escherichia coli; Flavin-Adenine Dinucleotide; Flavoproteins; Nucleotidyltransferases; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Riboflavin	2013
Bacterial flavin mononucleotide riboswitches as targets for flavin analogs. Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1103 Topics: DNA-Directed RNA Polymerases; Flavin Mononucleotide; Humans; Molecular Biology; Phosphotransferases (Alcohol Group Acceptor); Riboflavin; Riboswitch; Streptomyces	2014
Riboflavin-overproducing strains of Lactobacillus fermentum for riboflavin-enriched bread. Applied microbiology and biotechnology, 2014, Volume: 98, Issue:8 Topics: Bread; Chromatography, High Pressure Liquid; DNA Mutational Analysis; Drug Tolerance; Food Handling; Limosilactobacillus fermentum; Metabolic Engineering; Mutation; Riboflavin; Saccharomyces cerevisiae	2014
Photoinduced intramolecular charge transfer in an electronically modified flavin derivative: roseoflavin. The journal of physical chemistry. B, 2015, Jan-22, Volume: 119, Issue:3 Topics: Benzene; Electron Transport; Electrons; Gases; Models, Molecular; Molecular Conformation; Photochemical Processes; Quantum Theory; Riboflavin; Solvents; Thermodynamics; Vacuum; Water	2015
Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-d-riboflavin to the antibiotic roseoflavin. The FEBS journal, 2016, Volume: 283, Issue:8 Topics: Anti-Bacterial Agents; Binding Sites; Catalysis; Crystallography, X-Ray; Kinetics; Methylation; Methyltransferases; Models, Molecular; Protein Conformation; Riboflavin; S-Adenosylhomocysteine; S-Adenosylmethionine; Streptomyces	2016
Identification of the Key Enzyme of Roseoflavin Biosynthesis. Angewandte Chemie (International ed. in English), 2016, 05-10, Volume: 55, Issue:20 Topics: Bacterial Proteins; Chromatography, High Pressure Liquid; Mass Spectrometry; Methyltransferases; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Riboflavin; Streptomyces	2016
A Remarkable Oxidative Cascade That Replaces the Riboflavin C8 Methyl with an Amino Group during Roseoflavin Biosynthesis. Journal of the American Chemical Society, 2016, 07-13, Volume: 138, Issue:27 Topics: Flavin Mononucleotide; Oxidation-Reduction; Riboflavin; Streptomyces	2016
Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes. Journal of bacteriology, 2016, 12-01, Volume: 198, Issue:23 Topics: Anti-Bacterial Agents; Autotrophic Processes; Bacterial Proteins; Listeria monocytogenes; Riboflavin	2016
The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists. PLoS neglected tropical diseases, 2017, Volume: 11, Issue:4 Topics: Amino Acid Sequence; Animals; Cell Line; Crithidia fasciculata; Humans; Leishmania mexicana; Life Cycle Stages; Linear Models; Membrane Transport Proteins; Multigene Family; Protozoan Proteins; Rats; Riboflavin; Trypanosoma cruzi	2017
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting. Cell chemical biology, 2017, May-18, Volume: 24, Issue:5 Topics: Animals; Anti-Bacterial Agents; Base Sequence; Escherichia coli; Flavin Mononucleotide; Homeostasis; Methicillin-Resistant Staphylococcus aureus; Mice; Models, Molecular; Molecular Targeted Therapy; Protein Conformation; Pyrimidines; Riboflavin; Riboswitch; Staphylococcus aureus	2017
Two Are Better Than One: Dual Targeting of Riboswitches by Metabolite Analogs. Cell chemical biology, 2017, May-18, Volume: 24, Issue:5 Topics: Anti-Bacterial Agents; Biological Transport; Methicillin-Resistant Staphylococcus aureus; Molecular Targeted Therapy; Riboflavin; Riboswitch	2017
Characterization of the small flavin-binding dodecin in the roseoflavin producer Streptomyces davawensis. Microbiology (Reading, England), 2018, Volume: 164, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; Flavin Mononucleotide; Flavins; Gene Deletion; Gene Expression; Metabolome; Oxidative Stress; Protein Binding; Protein Multimerization; Protein Stability; Riboflavin; Streptomyces; Streptomyces coelicolor	2018
OPTIMIZATION OF THE CULTIVATION CONDITIONS AND THE BASIC MOLECULAR TOOLS FOR ROSEOFLAVIN PRODUCER STREPTOMYCES DAVAWENSIS. Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 2016, Volume: 78, Issue:4 Topics: Anti-Bacterial Agents; Bacillus cereus; Bacillus subtilis; Culture Media; DNA, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Micrococcus luteus; Plasmids; Polymerase Chain Reaction; Riboflavin; Staphylococcus aureus; Streptomyces; Transformation, Genetic	2016
Comparative biochemical and structural analysis of the flavin-binding dodecins from Microbiology (Reading, England), 2019, Volume: 165, Issue:10 Topics: Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Membrane Transport Proteins; Models, Molecular; Mutagenesis, Site-Directed; Protein Multimerization; Protein Stability; Riboflavin; Species Specificity; Streptomyces; Streptomyces coelicolor; Temperature	2019
Metabolic engineering of roseoflavin-overproducing microorganisms. Microbial cell factories, 2019, Aug-26, Volume: 18, Issue:1 Topics: Anti-Bacterial Agents; Bacillus subtilis; Corynebacterium glutamicum; Metabolic Engineering; Riboflavin; Streptomyces	2019
The roseoflavin producer Streptomyces davaonensis has a high catalytic capacity and specific genetic adaptations with regard to the biosynthesis of riboflavin. Environmental microbiology, 2020, Volume: 22, Issue:8 Topics: Adaptation, Physiological; Catalysis; Genetic Complementation Test; Riboflavin; Streptomyces; Vitamin B Complex	2020
The novel phosphatase RosC catalyzes the last unknown step of roseoflavin biosynthesis in Streptomyces davaonensis. Molecular microbiology, 2020, Volume: 114, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; Catalysis; Flavin Mononucleotide; Phosphoric Monoester Hydrolases; Riboflavin; Streptomyces	2020
Selection of Riboflavin Overproducing Strains of Lactic Acid Bacteria and Riboflavin Direct Quantification by Fluorescence. Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2280 Topics: Bacteriological Techniques; Culture Media; Drug Resistance, Bacterial; Fermented Foods; Fluorescence; Lactobacillales; Riboflavin	2021
A second riboflavin import system is present in flavinogenic Streptomyces davaonensis and supports roseoflavin biosynthesis. Molecular microbiology, 2021, Volume: 116, Issue:2 Topics: Bacillus subtilis; Membrane Transport Proteins; Riboflavin; Secondary Metabolism; Streptomyces; Streptomyces coelicolor	2021
Roseoflavin, a Natural Riboflavin Analogue, Possesses Antimicrobial agents and chemotherapy, 2022, 10-18, Volume: 66, Issue:10 Topics: Animals; Antimalarials; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Malaria; Mice; Plasmodium falciparum; Riboflavin	2022
Mechanistic Insights into Roseoflavin Synthesis by Journal of chemical information and modeling, 2023, 06-26, Volume: 63, Issue:12 Topics: Molecular Dynamics Simulation; Riboflavin; Rosa	2023
Efficient production of bacterial antibiotics aminoriboflavin and roseoflavin in eukaryotic microorganisms, yeasts. Microbial cell factories, 2023, Jul-20, Volume: 22, Issue:1 Topics: Anti-Bacterial Agents; Eukaryota; Riboflavin	2023