Page last updated: 2024-08-25

ropivacaine and dexmedetomidine

ropivacaine has been researched along with dexmedetomidine in 122 studies

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (3.28)29.6817
2010's56 (45.90)24.3611
2020's62 (50.82)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Kida, K; Masaki, E; Ohtani, N; Shoji, K; Yasui, Y1
Gerner, P1
Amodeo, FS; Brummett, CM; Lydic, R; Padda, AK; Welch, KB1
Elcicek, K; Kati, I; Tekin, M1
Bhattacharjee, DP; Chatterjee, N; Dawn, S; Ghosh, S; Paul, S1
Amodeo, FS; Brummett, CM; Hong, EK; Janda, AM; Lydic, R1
Albert, NT; Bernard, PM; Côté, M; Létourneau, DR; Rancourt, MP1
Kettner, SC; Marhofer, D; Marhofer, P; Pils, S; Weber, M; Zeitlinger, M1
Li, Q; Lin, YN; Liu, JC; Mao, ZX; Yang, RM1
Chen, GZ; Cui, YY; Dong, YL; Wang, W; Wu, HH; Yin, JB; Zhang, T1
Bala, I; Bharti, N; Praveen, R1
Ding, Z; Han, C; Jiang, X; Wu, X1
Keplinger, M; Kettner, SC; Kimberger, O; Marhofer, D; Marhofer, P; Zeitlinger, M1
Eksborg, S; Lönnqvist, PA; Lundblad, M; Marhofer, D1
Chen, GZ; Cui, YY; Kaye, AD; Mei, XP; Shen, XF; Wu, HH; Yin, JB; Zhai, MZ; Zhang, H; Zhu, X1
Cho, JE; Kil, HK; Kim, JY; Park, SJ1
Mahapatra, AK; Palo, N; Panigrahi, R; Prasad, A; Priyadarshi, A; Roy, R1
Chen, JY; Li, N; Xu, YQ1
Gu, Y; Huang, X; Li, Y; Qi, X; Rahe-Meyer, N; Wang, X; Wen, Y1
Feng, J; Li, J; Luan, H; Zhang, X; Zhao, Z; Zhu, P1
Deng, R; Hu, Z; Huang, X; Tu, W1
Liu, Y; Xin, Y; Yi, X; Zhao, Y1
Dutta, V; Jayant, A; Kumar, B; Mishra, AK1
Gaspar-Carrillo, SP; Mejía-Terrazas, GE; Peña-Riveron, AA; Velázquez-Delgado, E1
Andersen, JH; Dahl, JB; Grevstad, U; Jæger, P; Mathiesen, O; Siegel, H1
Dong, CS; Lu, Y; Sun, H; Wu, C; Yu, JM; Zhang, Y1
Halaszynski, T; Hu, X; Li, J; Wang, Q; Xia, F; Xu, X; Zhou, R1
Dong, B; Li, J; Ma, J; Wang, H; Wu, X1
Mitra, S; Purohit, S; Sharma, M1
Choi, YS; Do, HY; Kim, HW; Kim, SH; Park, SJ; Shin, S1
Ding, W; Guo, C; Jiang, J; Li, J; Li, W; Zeng, X1
Hu, Z; McQuillan, PM; Shen, J; Xu, L1
Chen, XN; Li, YL; Qi, DM; Sun, WG; Sun, YJ; Yang, SH1
Feng, J; Gu, X; Luan, H; Tian, L; Wu, Y; Yan, Y; Zhang, X; Zhao, Z; Zhu, P1
Chen, X; Hu, X; Wang, Y; Xu, J; Yang, X; Zhang, J1
Kapsokalyvas, I; Katsanevaki, A; Koraki, E; Stachtari, C; Stergiouda, Z; Trikoupi, A1
Baek, SH; Choi, JH; Kim, BS; Lee, DH1
Li, C; Zhang, W1
Huang, QX; Li, QF; Lin, H; Wang, P; Yang, DJ1
Li, B; Sun, M; Zhang, J; Zhang, S; Zhang, W1
Chen, Y; Ding, W; Li, D; Liu, H; Wang, H; Wang, L; Zeng, X1
Hua, H; Jiang, M; Liu, Z; Xu, T1
Feng, J; Luan, H; Tian, L; Wu, Y; Xiu, M; Xu, D; Zhang, X; Zhao, Z; Zhu, P1
He, WS; Liu, Z; Sun, HJ; Wang, XL; Wu, ZY; Yang, XC1
Dai, W; He, K; Tang, M1
Deng, Y; Li, M; Li, Y; Wang, H; Yao, Y1
Chung, W; Hong, B; Jo, Y; Jung, C; Kang, H; Kim, YH; Ko, Y; Lim, C1
Hattori, K; Kido, H; Komasawa, N; Minami, T; Omori, M1
Geng, J; Guo, XY; Li, M; Li, ZQ; Ma, D; Masters, J; Sun, YB; Wang, DX; Wang, SL; Yu, ZY1
Brummett, CM; Lirk, P1
Gao, YT; Liu, XF1
Bai, XL; Cheng, ZJ; Guo, Z; Jia, PY; Li, YN; Yang, JX; Zhang, EF; Zhao, XY1
Dai, WX; Lin, CX; Shu, LP; Wang, HL; Wei, QF; Zhang, GY; Zheng, RF1
Gupta, R; Jindal, S; Kataria, S; Mitra, S; Saroa, R1
Dong, BH; Li, J; Yang, JS; Ye, JM1
Bi, X; Cheng, Q; Lu, Y; Tian, H; Zhang, W1
Chao, L; Liu, Y; Qiu, D; Yang, Y1
Lai, J; Li, H; Liu, T; Qin, Z; Xia, Z; Xiang, C; Zhan, L; Zhang, M1
Hwang, JT; Hwang, SM; Jang, JS; Kim, DY; Kim, YB; Lee, HN; Lee, JJ; Lee, S; Lee, SS; Song, DK1
Chen, X; Feng, Y; Fu, F; Huang, X; Tang, Y; Yang, M1
Diwan, SM; Dongre, H; Khurjekar, K; Nair, A; Turan, A; Yamak Altinpulluk, E1
Ben Gabsia, A; Chkili, R; Daiki, M; Ferjani, M; Labbène, I; Najar, M; Rafrafi, A1
Bruno, TS; Cassu, RN; Costa, JS; Nicácio, GM; Nicácio, IP; Stelle, ABF1
Han, J; Xiong, H; Xu, S; Yao, F; Zhang, W; Zhu, A1
He, Z; Liu, Y; Sun, Z; Wu, X; Zhong, J; Zhu, X1
Dong, B; Hao, J; Luo, Z; Wu, Z1
Chen, G; Gong, M; Liu, Y1
Fan, J; Han, X; Leng, Y; Liu, Y; Ma, X; Xue, X; Yu, J1
Chapman, BC; Moore, R; Nelson, EC; Shepherd, B; Stanley, DJ1
Fan, W; Sun, J; Wang, B; Yang, H; Yang, Y; Zhang, H; Zhou, J1
Gao, F; Liu, J; Qian, M; Xu, P1
Basset, B; Bataille, B; Casalprim, J; Chassery, C; Chaubard, M; De Lussy, A; Delbos, A; Delbos, MC; Ferre, F; Marquis, C; Marty, P; Merouani, M; Naudin, C; Rontes, O; Vuillaume, C1
Li, Q; Li, Y; Liu, R; Ma, W; Wang, C; Zhang, Z1
Deng, F; Liao, C; Wang, L; Wu, Q; Zhang, W; Zhao, J1
Cai, M; Chen, X; Lei, X; Yu, J1
Ida, KK; Markuszewski, MJ; Marolf, V; Sandersen, C; Siluk, D; Struck-Lewicka, W1
Gao, P; Gao, Z; Li, Y; Qiu, G; Rao, J; Wang, Q; Wang, Y; Zhong, W1
Li, H; Ni, C; Sun, L; Wang, Q; Wei, S; Zhang, G; Zheng, H1
Liu, Y; Zhang, H; Zhang, W1
Cui, Y; Lei, J; Sun, Y; Xia, M; Yao, D1
Astuto, M; La Via, L; Messina, S; Morgana, A; Sanfilippo, F1
Chen, X; Gao, C; Jiang, Z; Wang, S; Xie, YH; Zhang, JP; Zhang, N; Zhang, W; Zhou, Y1
Jin, XB; Liu, C; Liu, LF; Luo, YR; Xiao, R; Xu, GH; Zhou, W1
Bornemann-Cimenti, H; Gebauer, D; Köstenberger, M; Labmayr, V; Leithner, A; Reinbacher, P; Rief, M; Sadoghi, P; Sandner-Kiesling, A; Schittek, GA; Simonis, H; Vielgut, I1
Jie-Ting, L; Jun, L; Min, W; Rong, T; Sheng-Hui, H; Yan, Z; Yi, L; Yi-Han, W1
Gupta, KK; Panda, BP; Singh, A; Singh, G1
Feng, JL; Mei, Z; Ni, JX; Ni, LF; Qian, XW; Song, CZ; Song, SB; Yao, SJ; Yu, J1
Marolf, V; Picavet, P; Sandersen, C; Selz, J; Spadavecchia, C; Tutunaru, A1
Guo, G; Liu, W; Wen, J; Zhao, Y; Zhou, H1
Cao, R; Fan, M; Hu, L; Li, J; Lu, S1
He, Y; Hu, R; Ning, R; Niu, J; Sun, H; Yang, N; Yu, J1
Chen, Z; Cui, K; Dang, X; Jiang, N; Su, S; Wang, Y1
Chai, X; Chu, L; Liao, B; Wang, XF; Wei, JM; Yang, JS; Zhang, R; Zhang, X; Zhao, YT; Zou, P1
Feng, XY; Lei, YJ; Wang, XR; Wang, ZH; Yang, J; Zhang, JW; Zhang, XR; Zhao, M1
Bao, N; Chen, Z; Gao, Y; He, Y; Papadimos, TJ; Shi, K; Wang, Q; Wu, Y; Xia, Y; Zhou, R1
Huang, Z; Liu, G; Shan, R; Sun, C; Wang, G; Wang, L; Zhang, X; Zhong, Y1
Fu, H; Jian, C; Shen, Y; Yu, L1
An, G; Fu, J; Li, Z; Wang, G; Zhang, X; Zhao, B; Zhao, X1
Hao, D; Zhang, Z1
Chen, L; Li, X; Luo, X; Shen, S; Wang, J; Xu, W1
Hou, Z; Qiu, Q; Wan, W1
Chen, X; Dong, S; Liao, L; Liu, J; Liu, Y; Zeng, L; Zhang, T1
Bagntasarian, S; Christidis, P; Koraki, E; Mantzoros, I; Sifaki, F; Theodoraki, K1
Chen, X; Liu, M; Prudence, B; Wang, B1
Chen, J; Ding, Z; Liu, Z; Lu, H; Zhao, E; Zhou, K; Zhou, Z1
Sun, W; Zhu, M1
Li, F; Liu, P; Qiao, H; Wang, R1
Kame, BS; Kumar, VU; Subramaniam, A1
Bagntasarian, S; Chatzopoulos, S; Koraki, E; Sifaki, F; Stachtari, C; Stergiouda, Z1
Chen, C; Chen, W; Gao, P; Li, YH; Lu, Y; Rao, J1
Li, Z; Lu, Y; Ma, X; Sun, H; Wang, S; Zhu, H1
Bosco, M; Marrone, F; Paventi, S; Pullano, C; Tomei, M1
Hao, C; Li, H; Luan, H; Zhang, X; Zhao, Z; Zhu, P1
Bai, X; Dai, W; Li, Z; Lyu, J; Zhang, X; Zheng, Z1
Fan, W; Guo, Y; Jiang, P; Wang, D; Wang, J; Yang, X1
Erdoes, G; Gerber, D; Guensch, DP; Terbeck, S1
Ali, KA; Deng, X; Fang, Z; Li, W; Li, Y1
Bhatia, P; Goel, AD; Goyal, S; Kothari, N; Kumari, K; Mohan, AM; Sethi, P; Sharma, A; Vyas, R1
Chen, J; Feng, J; Huang, F; Mo, X; Wu, X; Zeng, J1
Guo, L; Huang, Z; Li, F; Lin, F; Pan, L1
Feng, C; Fu, J; Li, Y; Lu, G; Sun, J; Wang, L; Xie, T1

Reviews

6 review(s) available for ropivacaine and dexmedetomidine

ArticleYear
The effect and safety of dexmedetomidine added to ropivacaine in brachial plexus block: A meta-analysis of randomized controlled trials.
    Medicine, 2018, Volume: 97, Issue:41

    Topics: Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Brachial Plexus Block; Dexmedetomidine; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; Ropivacaine; Time Factors

2018
Dexmedetomidine versus fentanyl as adjuvants to ropivacaine for epidural anaesthesia: A systematic review and meta-analysis.
    International journal of clinical practice, 2021, Volume: 75, Issue:5

    Topics: Anesthesia, Epidural; Anesthetics, Local; Dexmedetomidine; Fentanyl; Humans; Ropivacaine

2021
Evaluation of ropivacaine combined with dexmedetomidine versus ropivacaine alone for epidural anesthesia: A meta-analysis.
    Medicine, 2021, Apr-09, Volume: 100, Issue:14

    Topics: Adrenergic alpha-2 Receptor Agonists; Age Factors; Anesthesia, Epidural; Anesthetics, Local; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Male; Randomized Controlled Trials as Topic; Ropivacaine

2021
Evaluation of the effect of dexmedetomidine combined with ropivacaine in epidural labor analgesia: a systematic review and meta-analysis.
    Minerva anestesiologica, 2022, Volume: 88, Issue:10

    Topics: Amides; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Anesthetics, Local; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Pregnancy; Ropivacaine; Sufentanil

2022
Analgesic Effects of Ropivacaine Combined With Dexmedetomidine in Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2023, Volume: 38, Issue:3

    Topics: Abdominal Muscles; Analgesics; Anesthetics, Local; Cholecystectomy, Laparoscopic; Dexmedetomidine; Humans; Pain, Postoperative; Ropivacaine

2023
Effects of dexmedetomidine as an adjuvant to ropivacaine or ropivacaine alone on duration of postoperative analgesia: A systematic review and meta-analysis of randomized controlled trials.
    PloS one, 2023, Volume: 18, Issue:10

    Topics: Analgesia; Anesthetics, Local; Dexmedetomidine; Humans; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Ropivacaine; Sufentanil

2023

Trials

82 trial(s) available for ropivacaine and dexmedetomidine

ArticleYear
Postoperative pain status after intraoperative systemic dexmedetomidine and epidural neostigmine in patients undergoing lower abdominal surgery.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:11

    Topics: Abdomen; Adult; Amides; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthesia, General; Dexmedetomidine; Female; General Surgery; Humans; Intraoperative Period; Middle Aged; Neostigmine; Pain, Postoperative; Parasympathomimetics; Ropivacaine

2008
The effects of intravenous dexmedetomidine on spinal hyperbaric ropivacaine anesthesia.
    Journal of anesthesia, 2010, Volume: 24, Issue:4

    Topics: Adult; Amides; Analgesics, Non-Narcotic; Anesthesia, Spinal; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Ropivacaine

2010
Efficacy of intra-articular dexmedetomidine for postoperative analgesia in arthroscopic knee surgery.
    The Ceylon medical journal, 2010, Volume: 55, Issue:4

    Topics: Adolescent; Adult; Amides; Arthroscopy; Dexmedetomidine; Double-Blind Method; Female; Humans; Joint Diseases; Knee Joint; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Ropivacaine; Young Adult

2010
Posterior tibial nerve sensory blockade duration prolonged by adding dexmedetomidine to ropivacaine.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:4

    Topics: Adolescent; Adult; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Nerve Block; Prospective Studies; Ropivacaine; Tibial Nerve; Time Factors; Young Adult

2012
Dexmedetomidine as an adjuvant to ropivacaine prolongs peripheral nerve block: a volunteer study.
    British journal of anaesthesia, 2013, Volume: 110, Issue:3

    Topics: Adjuvants, Anesthesia; Adolescent; Adrenergic alpha-Agonists; Adult; Amides; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Heart Rate; Humans; Male; Nerve Block; Peripheral Nerves; Prospective Studies; Ropivacaine; Ulnar Nerve; Ultrasonography, Interventional; Young Adult

2013
Addition of dexmedetomidine to ropivacaine improves cervical plexus block.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2013, Volume: 51, Issue:2

    Topics: Adult; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Arterial Pressure; Cervical Plexus; Dexmedetomidine; Female; Heart Rate; Humans; Male; Nerve Block; Ropivacaine; Time Factors

2013
A dose-response study of caudal dexmedetomidine with ropivacaine in pediatric day care patients undergoing lower abdominal and perineal surgeries: a randomized controlled trial.
    Paediatric anaesthesia, 2014, Volume: 24, Issue:11

    Topics: Abdomen; Amides; Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Local; Child; Child, Preschool; Day Care, Medical; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infant; Male; Pain, Postoperative; Perineum; Prospective Studies; Ropivacaine; Treatment Outcome

2014
A pharmacodynamic evaluation of dexmedetomidine as an additive drug to ropivacaine for peripheral nerve blockade: A randomised, triple-blind, controlled study in volunteers.
    European journal of anaesthesiology, 2015, Volume: 32, Issue:11

    Topics: Adult; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Nerve Block; Paresthesia; Prospective Studies; Ropivacaine; Time Factors; Ulnar Nerve; Young Adult

2015
Dexmedetomidine as adjunct to ilioinguinal/iliohypogastric nerve blocks for pediatric inguinal hernia repair: an exploratory randomized controlled trial.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:9

    Topics: Amides; Anesthesia Recovery Period; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Hernia, Inguinal; Humans; Hypnotics and Sedatives; Infant; Male; Nerve Block; Pain, Postoperative; Prospective Studies; Ropivacaine

2015
The Effect of 1 µg/kg Dexmedetomidine Combined with High-Volume/Low-Concentration Caudal Ropivacaine in Children Undergoing Ambulatory Orchiopexy.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Ambulatory Care; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Arterial Pressure; Child, Preschool; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Heart Rate; Humans; Infant; Male; Orchiopexy; Pain Measurement; Pain, Postoperative; Ropivacaine

2015
Intra-articular Adjuvant Analgesics following Knee Arthroscopy: Comparison between Single and Double Dose Dexmedetomidine and Ropivacaine A Multicenter Prospective Double-blind Trial.
    Orthopaedic surgery, 2015, Volume: 7, Issue:3

    Topics: Adult; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Arthroscopy; Blood Pressure; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Heart Rate; Humans; Injections, Intra-Articular; Knee Joint; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Care; Prospective Studies; Ropivacaine; Young Adult

2015
Intrathecal dexmedetomidine as adjuvant to ropivacaine in hysteroscopic surgery: a prospective, randomized control study.
    International journal of clinical pharmacology and therapeutics, 2016, Volume: 54, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Amides; Anesthesia, Spinal; Anesthetics, Local; Dexmedetomidine; Female; Humans; Hysteroscopy; Prospective Studies; Ropivacaine; Single-Blind Method

2016
Effect of dexmedetomidine added to ropivacaine on ultrasound-guided transversus abdominis plane block for postoperative analgesia after abdominal hysterectomy surgery: a prospective randomized controlled trial.
    Minerva anestesiologica, 2016, Volume: 82, Issue:9

    Topics: Abdominal Muscles; Adult; Aged; Amides; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Humans; Hysterectomy; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine; Ultrasonography, Interventional

2016
Effect of Epidural Dexmedetomidine Combined With Ropivacaine in Labor Analgesia: A Randomized Double-Blinded Controlled Study.
    The Clinical journal of pain, 2017, Volume: 33, Issue:4

    Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Blood Pressure; Cesarean Section; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Humans; Labor Pain; Labor, Obstetric; Pain Measurement; Pregnancy; Ropivacaine; Young Adult

2017
Effect of Continuous Paravertebral Dexmedetomidine Administration on Intraoperative Anesthetic Drug Requirement and Post-Thoracotomy Pain Syndrome After Thoracotomy: A Randomized Controlled Trial.
    Journal of cardiothoracic and vascular anesthesia, 2017, Volume: 31, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Humans; Intraoperative Care; Middle Aged; Morphine; Nerve Block; Pain Measurement; Pain, Postoperative; Propofol; Ropivacaine; Syndrome; Thoracotomy; Young Adult

2017
Postoperative analgesia with dexmedetomidine in interscalene block. Comparative study.
    Revista espanola de anestesiologia y reanimacion, 2017, Volume: 64, Issue:3

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Amides; Analgesia; Analgesics; Anesthetics, Local; Arthroscopy; Clonidine; Dexmedetomidine; Drug Synergism; Electric Stimulation; Female; Hemodynamics; Humans; Male; Middle Aged; Motor Activity; Nerve Block; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine; Sensation; Shoulder; Single-Blind Method; Ultrasonography, Interventional; Young Adult

2017
Does Dexmedetomidine Have a Perineural Mechanism of Action When Used as an Adjuvant to Ropivacaine?: A Paired, Blinded, Randomized Trial in Healthy Volunteers.
    Anesthesiology, 2017, Volume: 126, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Amides; Anesthetics, Local; Dexmedetomidine; Drug Therapy, Combination; Humans; Male; Middle Aged; Nerve Block; Peripheral Nerves; Reference Values; Ropivacaine; Single-Blind Method; Young Adult

2017
The Analgesic Effect of Ropivacaine Combined With Dexmedetomidine for Incision Infiltration After Laparoscopic Cholecystectomy.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2016, Volume: 26, Issue:6

    Topics: Adult; Amides; Analgesics, Non-Narcotic; Anesthesia, Local; Anesthetics, Local; Cholecystectomy, Laparoscopic; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Gallbladder Diseases; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Care; Retrospective Studies; Ropivacaine; Treatment Outcome

2016
Dexmedetomidine Added to Local Anesthetic Mixture of Lidocaine and Ropivacaine Enhances Onset and Prolongs Duration of a Popliteal Approach to Sciatic Nerve Blockade.
    Clinical therapeutics, 2017, Volume: 39, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amides; Anesthetics, Local; Animals; Dexmedetomidine; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Ropivacaine; Sciatic Nerve

2017
Adding dexmedetomidine to ropivacaine for femoral nerve block inhibits local inflammatory response.
    Minerva anestesiologica, 2017, Volume: 83, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Anesthetics, Local; Arthroplasty, Replacement, Knee; Dexmedetomidine; Drug Therapy, Combination; Female; Femoral Nerve; Humans; Inflammation; Male; Nerve Block; Postoperative Complications; Prospective Studies; Ropivacaine

2017
Postoperative Analgesia After Wound Infiltration With Tramadol and Dexmedetomidine as an Adjuvant to Ropivacaine for Lumbar Discectomies: A Randomized-controlled Clinical Trial.
    Journal of neurosurgical anesthesiology, 2017, Volume: 29, Issue:4

    Topics: Adult; Aged; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Diskectomy; Double-Blind Method; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine; Tramadol

2017
Comparison of Dexmedetomidine and Fentanyl as an Adjuvant to Ropivacaine for Postoperative Epidural Analgesia in Pediatric Orthopedic Surgery.
    Yonsei medical journal, 2017, Volume: 58, Issue:3

    Topics: Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Female; Fentanyl; Humans; Injections, Epidural; Leg; Male; Orthopedic Procedures; Pain, Postoperative; Postoperative Period; Ropivacaine; Treatment Outcome

2017
Effect of Adding Dexmedetomidine to Ropivacaine on Ultrasound-Guided Dual Transversus Abdominis Plane Block after Gastrectomy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017, Volume: 21, Issue:6

    Topics: Abdominal Muscles; Adult; Aged; Amides; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Gastrectomy; Humans; Male; Middle Aged; Nerve Block; Outcome Assessment, Health Care; Prospective Studies; Ropivacaine; Ultrasonography, Interventional

2017
Efficacy of US-guided transversus abdominis plane block and rectus sheath block with ropivacaine and dexmedetomidine in elderly high-risk patients.
    Minerva anestesiologica, 2018, Volume: 84, Issue:1

    Topics: Abdominal Muscles; Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Humans; Male; Nerve Block; Prospective Studies; Rectus Abdominis; Risk Factors; Ropivacaine; Treatment Outcome; Ultrasonography, Interventional

2018
[Effects of different doses of dexmedetomidine combined with ropivacaine for brachial plexus nerve block in children undergoing polydactyly surgery].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2017, Jun-20, Volume: 37, Issue:6

    Topics: Amides; Anesthetics, Local; Brachial Plexus; Child; Dexmedetomidine; Double-Blind Method; Humans; Nerve Block; Polydactyly; Ropivacaine

2017
Effect of dexmedetomidine as an adjuvant to ropivacaine for wound infiltration in patients undergoing open gastrectomy: A prospective randomized controlled trial.
    Medicine, 2017, Volume: 96, Issue:38

    Topics: Adult; Aged; Amides; Analgesia, Patient-Controlled; Analgesics; Anesthetics, Local; Chemotherapy, Adjuvant; Dexmedetomidine; Double-Blind Method; Female; Gastrectomy; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Ropivacaine; Sufentanil; Treatment Outcome; Wound Healing

2017
Multilevel Thoracic Paravertebral Block Using Ropivacaine With/Without Dexmedetomidine in Video-Assisted Thoracoscopic Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2018, Volume: 32, Issue:1

    Topics: Adult; Aged; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nerve Block; Pain, Postoperative; Prospective Studies; Ropivacaine; Thoracic Surgery, Video-Assisted; Thoracic Vertebrae

2018
Dexmedetomidine as an adjuvant to 0.5% ropivacaine in ultrasound-guided axillary brachial plexus block.
    Journal of clinical pharmacy and therapeutics, 2018, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Brachial Plexus Block; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Forearm; Hand; Humans; Male; Middle Aged; Prospective Studies; Ropivacaine; Ultrasonography, Interventional; Young Adult

2018
EC50 of Epidural Ropivacaine Combined With Dexmedetomidine for Labor Analgesia.
    The Clinical journal of pain, 2018, Volume: 34, Issue:10

    Topics: Adult; Analgesia, Obstetrical; Analgesics; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Labor Pain; Labor, Obstetric; Pregnancy; Ropivacaine

2018
Paravertebral dexmedetomidine as an adjuvant to ropivacaine protects against independent lung injury during one-lung ventilation: a preliminary randomized clinical trial.
    BMC anesthesiology, 2018, 06-15, Volume: 18, Issue:1

    Topics: Acute Lung Injury; Adult; Aged; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Inflammation Mediators; Male; Middle Aged; One-Lung Ventilation; Retrospective Studies; Ropivacaine

2018
Investigation of single-dose thoracic paravertebral analgesia for postoperative pain control after thoracoscopic lobectomy - A randomized controlled trial.
    International journal of surgery (London, England), 2018, Volume: 57

    Topics: Aged; Amides; Analgesics; Anesthesia, Epidural; Dexmedetomidine; Female; Humans; Intraoperative Care; Male; Middle Aged; Morphine; Nerve Block; Pain Management; Pain, Postoperative; Pneumonectomy; Postoperative Period; Prospective Studies; Ropivacaine; Thoracoscopy; Treatment Outcome

2018
Analgesic effect of Ropivacaine combined with Dexmedetomidine on brachial plexus block.
    BMC anesthesiology, 2018, 08-16, Volume: 18, Issue:1

    Topics: Adult; Analgesics, Non-Narcotic; Brachial Plexus Block; Dexmedetomidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Middle Aged; Oxygen; Pain; Ropivacaine; Time Factors; Visual Analog Scale; Young Adult

2018
Effect of dexmedetomidine added to ropivicaine for caudal anesthesia in patients undergoing hemorrhoidectomy: A prospective randomized controlled trial.
    Medicine, 2018, Volume: 97, Issue:34

    Topics: Adult; Amides; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anesthetics, Local; Dexmedetomidine; Drug Therapy, Combination; Female; Hemorrhoidectomy; Humans; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Ropivacaine; Treatment Outcome

2018
The effect of dexmedetomidine in coracoid approach brachial plexus block under dual stimulation.
    Medicine, 2018, Volume: 97, Issue:39

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Amides; Anesthesia; Anesthetics, Local; Brachial Plexus Block; Dexmedetomidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Narcotics; Pain Measurement; Prospective Studies; Ropivacaine; Time Factors; Tramadol; Young Adult

2018
[Effect of dexmedetomidine on supraclavicular brachial plexus block: a randomized double blind prospective study].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2018, Oct-18, Volume: 50, Issue:5

    Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Arthroscopy; Brachial Plexus; Brachial Plexus Block; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Prospective Studies; Ropivacaine; Shoulder Joint

2018
Sedation with dexmedetomidine prolongs the analgesic duration of brachial plexus block: a randomised controlled trial.
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:3

    Topics: Adult; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Local; Brachial Plexus Block; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Middle Aged; Orthopedic Procedures; Ropivacaine; Time Factors; Upper Extremity

2019
Sedative effect of dexmedetomidine in spinal-epidural anesthesia on hysteromyomectomy.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:6(Special)

    Topics: Administration, Intravenous; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Consciousness; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Injections, Spinal; Lidocaine; Middle Aged; Propofol; Ropivacaine; Time Factors; Uterine Myomectomy

2018
Ultrasound-Guided Continuous Femoral Nerve Block with Dexmedetomidine Combined with Low Concentrations of Ropivacaine for Postoperative Analgesia in Elderly Knee Arthroplasty.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2019, Volume: 28, Issue:5

    Topics: Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Arthroplasty, Replacement, Knee; Dexmedetomidine; Drug Combinations; Female; Femoral Nerve; Humans; Male; Nerve Block; Pain, Postoperative; Ropivacaine; Treatment Outcome; Ultrasonography; Visual Analog Scale

2019
A Randomized Double Blinded Trial Comparing Dexmedetomidine With Dexamethasone as an Adjunct to Ropivacaine in Ultrasound Guided Interscalene Block for Arthroscopic Shoulder Surgery.
    Asian journal of anesthesiology, 2019, Volume: 57, Issue:1

    Topics: Adult; Arthroscopy; Brachial Plexus Block; Dexamethasone; Dexmedetomidine; Double-Blind Method; Female; Humans; Male; Outcome Assessment, Health Care; Pain, Postoperative; Ropivacaine; Shoulder; Ultrasonography, Interventional

2019
The Effect of Dexmedetomidine Added to Preemptive Ropivacaine Infiltration on Postoperative Pain After Lumbar Fusion Surgery: A Randomized Controlled Trial.
    Spine, 2019, Oct-01, Volume: 44, Issue:19

    Topics: Anesthetics, Local; Dexmedetomidine; Humans; Lumbar Vertebrae; Morphine; Pain, Postoperative; Ropivacaine; Spinal Fusion

2019
Dexmedetomidine versus sufentanil with high- or low-concentration ropivacaine for labor epidural analgesia: A randomized trial.
    The journal of obstetrics and gynaecology research, 2019, Volume: 45, Issue:11

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Blood Pressure; Dexmedetomidine; Female; Heart Rate; Humans; Labor Pain; Labor, Obstetric; Pain Measurement; Pregnancy; Ropivacaine; Sufentanil; Treatment Outcome

2019
The impact of dexmedetomidine added to ropivicaine for transversus abdominis plane block on stress response in laparoscopic surgery: a randomized controlled trial.
    BMC anesthesiology, 2019, 10-11, Volume: 19, Issue:1

    Topics: Abdominal Muscles; Adrenergic alpha-2 Receptor Agonists; Adult; Anesthetics, Local; Blood Pressure; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Laparoscopy; Middle Aged; Nerve Block; Prospective Studies; Ropivacaine; Stress, Physiological; Ultrasonography, Interventional

2019
Dexmedetomidine combined with interscalene brachial plexus block has a synergistic effect on relieving postoperative pain after arthroscopic rotator cuff repair.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2020, Volume: 28, Issue:7

    Topics: Adult; Aged; Anesthetics, Local; Arthroscopy; Body Mass Index; Brachial Plexus Block; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Interleukin-1beta; Interleukin-6; Interleukin-8; Magnetic Resonance Imaging; Male; Middle Aged; Pain, Postoperative; Patient Satisfaction; Postoperative Period; Ropivacaine; Rotator Cuff; Rotator Cuff Injuries; Visual Analog Scale

2020
Comparison of the ED50 of intrathecal hyperbaric ropivacaine co-administered with or without intrathecal dexmedetomidine for cesarean section: A prospective, double-blinded, randomized dose-response trial using up-down sequential allocation method.
    Journal of clinical anesthesia, 2020, Volume: 62

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dexmedetomidine; Double-Blind Method; Female; Humans; Injections, Spinal; Pregnancy; Prospective Studies; Ropivacaine

2020
Postoperative analgesia after wound infiltration with Dexmedetomidine and Ropivacaine versus Ropivacaine alone for lumbar discectomies: a randomized-controlled trial.
    La Tunisie medicale, 2019, Volume: 97, Issue:12

    Topics: Adult; Analgesia; Analgesics, Opioid; Dexmedetomidine; Diskectomy; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Pain Management; Pain, Postoperative; Ropivacaine; Surgical Wound

2019
Comparison of intraperitoneal ropivacaine and ropivacaine-dexmedetomidine for postoperative analgesia in cats undergoing ovariohysterectomy.
    Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:3

    Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Cats; Dexmedetomidine; Double-Blind Method; Female; Hysterectomy; Injections, Intraperitoneal; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine

2020
Impacts of different administration modes of dexmedetomidine with 0.5% ropivacaine on intercostal nerve block.
    Annals of palliative medicine, 2020, Volume: 9, Issue:2

    Topics: Adult; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Female; Humans; Intercostal Nerves; Male; Nerve Block; Pain, Postoperative; Prospective Studies; Ropivacaine; Young Adult

2020
Protective effect of dexmedetomidine infusion combined with epidural blockade on postoperative complications after surgery: A prospective randomized controlled clinical trial.
    The Journal of international medical research, 2020, Volume: 48, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; China; Dexmedetomidine; Female; Humans; Infusions, Parenteral; Male; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine

2020
Addition of dexmedetomidine to ropivacaine for local infiltration anaesthesia improves analgesic efficacy after tonsillectomy and adenoidectomy: A randomized controlled trial.
    International journal of pediatric otorhinolaryngology, 2020, Volume: 137

    Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Anesthesia, Local; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Female; Humans; Male; Pain Management; Pain Measurement; Pain, Postoperative; Ropivacaine; Time Factors; Tonsillectomy

2020
Comparison of ropivacaine plus sufentanil and ropivacaine plus dexmedetomidine for labor epidural analgesia: A randomized controlled trial protocol.
    Medicine, 2020, Sep-04, Volume: 99, Issue:36

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Pregnancy; Ropivacaine; Sufentanil

2020
Total knee arthroplasty under quadruple nerve block with ropivacaine 0.32%: effect of addition of intravenous dexmedetomidine to intravenous dexamethasone on analgesic duration.
    Regional anesthesia and pain medicine, 2021, Volume: 46, Issue:2

    Topics: Analgesics; Anesthetics, Local; Arthroplasty, Replacement, Knee; Dexamethasone; Dexmedetomidine; Double-Blind Method; Femoral Nerve; Humans; Nerve Block; Pain, Postoperative; Ropivacaine

2021
Nalbuphine and dexmedetomidine as adjuvants to ropivacaine in ultrasound-guided erector spinae plane block for video-assisted thoracoscopic lobectomy surgery: A randomized, double-blind, placebo-controlled trial.
    Medicine, 2021, Aug-13, Volume: 100, Issue:32

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nalbuphine; Nerve Block; Pain, Postoperative; Paraspinal Muscles; Peripheral Nerves; Pneumonectomy; Ropivacaine; Thoracic Surgery, Video-Assisted; Treatment Outcome; Ultrasonography, Interventional

2021
Dexmedetomidine Added to Ropivacaine for Ultrasound-guided Erector Spinae Plane Block Prolongs Analgesia Duration and Reduces Perioperative Opioid Consumption After Thoracotomy: A Randomized, Controlled Clinical Study.
    The Clinical journal of pain, 2021, 10-12, Volume: 38, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Dexmedetomidine; Humans; Nerve Block; Pain, Postoperative; Ropivacaine; Thoracotomy; Ultrasonography, Interventional

2021
Dexmedetomidine Combined with Femoral Nerve Block Provides Effective Analgesia Similar to Femoral Nerve Combined with Sciatic Nerve Block in Patients Undergoing Total Knee Arthroplasty: A Randomized Controlled Study.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthetics, Local; Arthroplasty, Replacement, Knee; Dexmedetomidine; Female; Femoral Nerve; Humans; Male; Middle Aged; Nerve Block; Pain Management; Pain Measurement; Pain, Postoperative; Ropivacaine; Sciatic Nerve

2022
Combined femoral and popliteal nerve block is superior to local periarticular infiltration anaesthesia for postoperative pain control after total knee arthroplasty.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022, Volume: 30, Issue:12

    Topics: Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Arthroplasty, Replacement, Knee; Dexmedetomidine; Femoral Nerve; Humans; Nerve Block; Pain, Postoperative; Ropivacaine

2022
Dexmedetomidine combined with ropivacaine for erector spinae plane block after posterior lumbar spine surgery: a randomized controlled trial.
    BMC musculoskeletal disorders, 2022, Mar-11, Volume: 23, Issue:1

    Topics: Child; Dexmedetomidine; Humans; Nerve Block; Pain, Postoperative; Paraspinal Muscles; Ropivacaine

2022
Evaluation of Dexmedetomidine as an Adjuvant to Ropivacaine in Transversus Abdominis Plane Block for Postoperative Analgesia in Unilateral Infraumbilical Surgeries-A Randomized Prospective Trial.
    Asian journal of anesthesiology, 2022, 03-01, Volume: 60, Issue:1

    Topics: Abdominal Muscles; Adolescent; Adult; Aged; Analgesia; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Middle Aged; Pain, Postoperative; Prospective Studies; Ropivacaine; Ultrasonography, Interventional; Young Adult

2022
Determination of the Dose-Response Relationship of Epidural Dexmedetomidine Combined with Ropivacaine for Labor Analgesia.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Pregnancy; Ropivacaine

2022
Effects of perineural dexmedetomidine combined with ropivacaine on postoperative methadone requirements in dogs after tibial plateau levelling osteotomy: a two-centre study.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:3

    Topics: Anesthetics, Local; Animals; Dexmedetomidine; Dog Diseases; Dogs; Hospitals, Animal; Hospitals, Teaching; Methadone; Osteotomy; Pain, Postoperative; Prospective Studies; Ropivacaine; Sciatic Nerve

2022
Efficacy and safety of dexmedetomidine-ropivacaine versus sufentanil-ropivacaine for epidural labor analgesia: a randomized controlled trial.
    Annals of palliative medicine, 2022, Volume: 11, Issue:4

    Topics: Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Female; Humans; Infant, Newborn; Pain; Ropivacaine; Sufentanil

2022
Effect of intratracheal dexmedetomidine combined with ropivacaine on postoperative sore throat: a prospective randomised double-blinded controlled trial.
    BMC anesthesiology, 2022, 05-14, Volume: 22, Issue:1

    Topics: Dexmedetomidine; Humans; Intubation, Intratracheal; Pain; Pharyngitis; Postoperative Complications; Prospective Studies; Ropivacaine

2022
Ropivacaine with Dexmedetomidine or Dexamethasone in a Thoracic Paravertebral Nerve Block Combined with an Erector Spinae Plane Block for Thoracoscopic Lobectomy Analgesia: A Randomized Controlled Trial.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Analgesia; Anesthesia, General; Dexamethasone; Dexmedetomidine; Humans; Nerve Block; Ropivacaine; Sufentanil

2022
Dexmedetomidine prolongs the duration of local anesthetics when used as an adjuvant through both perineural and systemic mechanisms: a prospective randomized double-blinded trial.
    BMC anesthesiology, 2022, 06-07, Volume: 22, Issue:1

    Topics: Anesthetics, Local; Brachial Plexus Block; Dexmedetomidine; Humans; Prospective Studies; Ropivacaine

2022
Assessment of the effect of perineural dexmedetomidine on oxidative stress during peritoneal dialysis catheter insertion: a randomized, controlled trial.
    International urology and nephrology, 2022, Volume: 54, Issue:12

    Topics: Anesthetics, Local; Catheters; Dexmedetomidine; Glutathione Peroxidase; Humans; Kidney Failure, Chronic; Malondialdehyde; Nerve Block; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Ropivacaine; Superoxide Dismutase; Ultrasonography, Interventional

2022
Effects of ultrasound-guided erector spinae plane block with dexmedetomidine combined with ropivacaine of the same dose and different concentrations on analgesic effect and rehabilitation quality of patients undergoing thoracoscopic wedge resection of the
    BMC anesthesiology, 2022, 07-16, Volume: 22, Issue:1

    Topics: Anesthetics, Local; Cough; Dexmedetomidine; Humans; Lung; Nerve Block; Pain, Postoperative; Prospective Studies; Ropivacaine; Ultrasonography, Interventional

2022
Opioid-free anesthesia compared to opioid anesthesia for laparoscopic radical colectomy with pain threshold index monitoring: a randomized controlled study.
    BMC anesthesiology, 2022, 07-29, Volume: 22, Issue:1

    Topics: Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia; Blood Glucose; Colectomy; Dexmedetomidine; Humans; Laparoscopy; Pain Threshold; Pain, Postoperative; Ropivacaine; Sevoflurane

2022
Optimal Dose of Dexmedetomidine for Preemptive Analgesia Combined with Transversus Abdominis Plane Block after Colon Cancer Surgery.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2022, Volume: 89, Issue:4

    Topics: Abdominal Muscles; Analgesia; Anesthetics, Local; Colonic Neoplasms; Dexmedetomidine; Double-Blind Method; Humans; Pain; Pain, Postoperative; Prospective Studies; Ropivacaine

2022
Study on the protective mechanism of dexmedetomidine on the liver of perioperative diabetic patients: A randomized controlled trial.
    Medicine, 2022, Oct-14, Volume: 101, Issue:41

    Topics: Adrenergic alpha-2 Receptor Agonists; Biomarkers; Blood Glucose; Cholesterol; Dexmedetomidine; Diabetes Mellitus, Type 2; Humans; Interleukin-6; Liver; Ropivacaine; Saline Solution; Superoxide Dismutase; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha

2022
The Effect of Ultrasound-guided Bilateral Erector Spinae Plane Block With and Without Dexmedetomidine on Intraoperative and Postoperative Pain in Laparoscopic Cholecystectomies: A Randomized, Controlled, Double-blind, Prospective Trial.
    Pain physician, 2022, Volume: 25, Issue:7

    Topics: Analgesics, Opioid; Anesthetics, Local; Cholecystectomy, Laparoscopic; Dexmedetomidine; Humans; Morphine; Nerve Block; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Remifentanil; Ropivacaine; Saline Solution; Ultrasonography, Interventional

2022
Effect of different doses of epidural dexmedetomidine on reducing visceral traction reaction for cesarean section: a double-blind randomized controlled trial.
    Journal of anesthesia, 2023, Volume: 37, Issue:3

    Topics: Anesthetics, Local; Cesarean Section; Dexmedetomidine; Double-Blind Method; Female; Humans; Infant, Newborn; Pregnancy; Ropivacaine; Traction; Vomiting

2023
Dexmedetomidine Prolongs the Analgesic Effects of Periarticular Infiltration Analgesia following Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial.
    The Journal of arthroplasty, 2023, Volume: 38, Issue:7

    Topics: Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Dexmedetomidine; Double-Blind Method; Epinephrine; Humans; Pain Management; Pain, Postoperative; Postoperative Complications; Prospective Studies; Ropivacaine

2023
Spinal Anaesthesia for Urological Surgery: A Comparison of Isobaric Solutions of Levobupivacaine and Ropivacaine with Dexmedetomidine.
    Ethiopian journal of health sciences, 2023, Volume: 33, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Humans; Levobupivacaine; Prospective Studies; Ropivacaine

2023
Dexmedetomidine as an adjuvant to scalp block in patients undergoing elective craniotomy: A prospective randomized controlled trial.
    Clinical neurology and neurosurgery, 2023, Volume: 227

    Topics: Craniotomy; Dexmedetomidine; Fentanyl; Humans; Pain, Postoperative; Propofol; Prospective Studies; Remifentanil; Ropivacaine; Scalp

2023
Effect of different modes of administration of dexmedetomidine on the quality of recovery in ambulatory thyroidectomy: a randomized, controlled trial.
    The Journal of international medical research, 2023, Volume: 51, Issue:5

    Topics: Adjuvants, Immunologic; Dexmedetomidine; Humans; Pain; Ropivacaine; Thyroidectomy

2023
Low-dose intranasal dexmedetomidine premedication improves epidural labor analgesia onset and reduces procedural pain on epidural puncture: a prospective randomized double-blind clinical study.
    BMC anesthesiology, 2023, 05-30, Volume: 23, Issue:1

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Humans; Infant, Newborn; Pain; Pain Management; Pain, Procedural; Prospective Studies; Punctures; Ropivacaine; Sufentanil

2023
Effect of interscalene brachial plexus block with dexmedetomidine and ropivacaine on postoperative analgesia in patients undergoing arthroscopic shoulder surgery: a randomized controlled clinical trial.
    Trials, 2023, Jun-12, Volume: 24, Issue:1

    Topics: Adult; Analgesia; Brachial Plexus Block; Dexmedetomidine; Humans; Pain; Ropivacaine; Shoulder; Sufentanil

2023
Perineural dexmedetomidine in femoral nerve blocks increases the duration of postoperative analgesia for anterolateral thigh flap donor sites in patients with oral cancer.
    Neuroscience letters, 2023, 08-24, Volume: 812

    Topics: Amides; Analgesia; Anesthetics, Local; Bradycardia; Dexmedetomidine; Femoral Nerve; Humans; Mouth Neoplasms; Pain, Postoperative; Ropivacaine; Thigh

2023
Effect of erector spinae plane block with different doses of dexmedetomidine as adjuvant for ropivacaine on the postoperative quality of recovery after video-assisted thoracoscopic lobectomy surgery: a randomized controlled trial.
    BMC anesthesiology, 2023, 08-07, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Dexmedetomidine; Flurbiprofen; Humans; Middle Aged; Nerve Block; Pain, Postoperative; Postoperative Nausea and Vomiting; Ropivacaine; Thoracic Surgery, Video-Assisted; Ultrasonography, Interventional; Young Adult

2023
Dexamethasone and dexmedetomidine as adjuvants to ropivacaine do not prolong analgesia in wound infiltration for lumbar spinal fusion: a prospective randomized controlled study.
    Journal of orthopaedic surgery and research, 2023, Sep-04, Volume: 18, Issue:1

    Topics: Adult; Agnosia; Analgesia; Analgesics, Opioid; Dexamethasone; Dexmedetomidine; Humans; Hydromorphone; Lumbar Vertebrae; Pain; Prospective Studies; Ropivacaine; Spinal Fusion

2023
Comparison of Caudal Dexmedetomidine and Midazolam as an Adjuvant to Ropivacaine for Postoperative Pain Relief in Children Undergoing Infra-Umbilical Surgeries: A Randomized Controlled Trial.
    Asian journal of anesthesiology, 2023, 06-01, Volume: 61, Issue:2

    Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Agnosia; Child; Child, Preschool; Dexmedetomidine; Drug-Related Side Effects and Adverse Reactions; Humans; Midazolam; Pain, Postoperative; Ropivacaine

2023
Intrathecal dexmedetomidine as an adjuvant to plain ropivacaine for spinal anesthesia during cesarean section: a prospective, double-blinded, randomized trial for ED
    BMC anesthesiology, 2023, 09-25, Volume: 23, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Cesarean Section; Dexmedetomidine; Female; Humans; Infant, Newborn; Pregnancy; Prospective Studies; Ropivacaine

2023
Effects of Subcostal Anterior Quadratus Lumborum Block with and without Dexmedetomidine on Postoperative Rehabilitation in Patients Undergoing Laparoscopic Renal Surgery: A Prospective Double-Blinded Randomized Controlled Study.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Humans; Kidney; Laparoscopy; Pain, Postoperative; Prospective Studies; Ropivacaine

2023

Other Studies

34 other study(ies) available for ropivacaine and dexmedetomidine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
"Above all, do no harm": hippocrates.
    Anesthesiology, 2009, Volume: 111, Issue:5

    Topics: Amides; Anesthetics, Local; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Nerve Block; Rats; Ropivacaine; Sciatic Nerve

2009
Perineural dexmedetomidine added to ropivacaine causes a dose-dependent increase in the duration of thermal antinociception in sciatic nerve block in rat.
    Anesthesiology, 2009, Volume: 111, Issue:5

    Topics: Adrenergic alpha-Agonists; Amides; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Male; Nerve Block; Pain Management; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve

2009
Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current.
    Anesthesiology, 2011, Volume: 115, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Analgesia; Anesthetics, Local; Animals; Behavior, Animal; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dexmedetomidine; Dose-Response Relationship, Drug; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Hypnotics and Sedatives; Idazoxan; Male; Nerve Block; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Prazosin; Pyrimidines; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve

2011
Inhibiting spinal neuron-astrocytic activation correlates with synergistic analgesia of dexmedetomidine and ropivacaine.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Amides; Analgesia; Animals; Astrocytes; Chronic Pain; Dexmedetomidine; Drug Synergism; Freund's Adjuvant; Glial Fibrillary Acidic Protein; Injections, Spinal; Male; Neurons; Rats, Sprague-Dawley; Ropivacaine; Spinal Cord Dorsal Horn

2014
[Application of dexmedetomidine combined with ropivacaine in the cesarean section under epidural anesthesia].
    Zhonghua yi xue za zhi, 2014, Dec-02, Volume: 94, Issue:44

    Topics: Amides; Analgesics; Anesthesia, Epidural; Anesthetics, Local; Cesarean Section; Dexmedetomidine; Drug Combinations; Female; Fentanyl; Humans; Pain, Postoperative; Pregnancy; Ropivacaine

2014
Dexmedetomidine Dose-Dependently Attenuates Ropivacaine-Induced Seizures and Negative Emotions Via Inhibiting Phosphorylation of Amygdala Extracellular Signal-Regulated Kinase in Mice.
    Molecular neurobiology, 2016, Volume: 53, Issue:4

    Topics: Amides; Amygdala; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Emotions; Extracellular Signal-Regulated MAP Kinases; Male; Mice, Inbred C57BL; Phosphorylation; Reaction Time; Ropivacaine; Seizures

2016
Single Shot Adductor Canal Block for Postoperative Analgesia of Pediatric Patellar Dislocation Surgery: A Case-Series Report.
    Medicine, 2015, Volume: 94, Issue:48

    Topics: Adolescent; Amides; Anesthetics, Local; Child; Dexmedetomidine; Female; Femoral Nerve; Humans; Hypnotics and Sedatives; Male; Nerve Block; Orthopedic Procedures; Pain, Postoperative; Patellar Dislocation; Ropivacaine

2015
Dexmedetomidine reduces neuropathic pain in a rat model of skin/muscle incision and retraction.
    Asian journal of surgery, 2017, Volume: 40, Issue:1

    Topics: Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Dermatologic Surgical Procedures; Dexmedetomidine; Drug Administration Schedule; Drug Therapy, Combination; Injections; Male; Muscle, Skeletal; Neuralgia; Pain Measurement; Pain, Postoperative; Preoperative Care; Random Allocation; Rats; Rats, Sprague-Dawley; Ropivacaine; Thigh; Treatment Outcome

2017
Effects of Intraneural Injection of Dexmedetomidine in Combination With Ropivacaine in Rat Sciatic Nerve Block.
    Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:4

    Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Autonomic Nerve Block; Dexmedetomidine; Drug Therapy, Combination; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve

2018
[Analgesic effects of intravenous infusion of dexmedetomidine combined with local infiltration of ropivacaine in patients underwent nasal endoscopic surgery].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2016, Apr-20, Volume: 30, Issue:8

    Topics: Amides; Analgesics; Dexmedetomidine; Double-Blind Method; Endoscopy; Humans; Infusions, Intravenous; Nasal Cavity; Pain, Postoperative; Ropivacaine

2016
[Ultrasound-guided Thoracic Epidural and Spinal Anesthesia for the Management of Patients Undergoing Systemic Neurofibroma Resection].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:9

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Bupivacaine; Dexmedetomidine; Humans; Male; Neurofibroma; Pain, Postoperative; Pulmonary Disease, Chronic Obstructive; Ropivacaine; Skin Neoplasms; Ultrasonography

2016
Dexmedetomidine enhances ropivacaine-induced sciatic nerve injury in diabetic rats.
    British journal of anaesthesia, 2019, Volume: 122, Issue:1

    Topics: Adjuvants, Anesthesia; Anesthetics, Local; Animals; Cytokines; Dexmedetomidine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Synergism; Inflammation Mediators; Male; Nerve Block; Neural Conduction; Peripheral Nerve Injuries; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve

2019
Regional anaesthesia, diabetic neuropathy, and dexmedetomidine: a neurotoxic combination?
    British journal of anaesthesia, 2019, Volume: 122, Issue:1

    Topics: Anesthesia, Conduction; Animals; Dexmedetomidine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Rats; Ropivacaine; Sciatic Nerve

2019
Dose-dependent neurotoxicity caused by the addition of perineural dexmedetomidine to ropivacaine for continuous femoral nerve block in rabbits.
    The Journal of international medical research, 2019, Volume: 47, Issue:6

    Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Femoral Nerve; Nerve Block; Neurotoxicity Syndromes; Rabbits; Ropivacaine

2019
Topical anesthetic analgesic therapy using the combination of ropivacaine and dexmedetomidine: hyaluronic acid modified long-acting nanostructured lipid carriers containing a skin penetration enhancer.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Animals; BALB 3T3 Cells; Dexmedetomidine; Drug Carriers; Drug Liberation; Hyaluronic Acid; Lipids; Mice; Nanoparticles; Nanostructures; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Ropivacaine; Skin Absorption; Vitamin E

2019
Bilateral erector spinae plane block for scoliosis surgery: Case series.
    Revista espanola de anestesiologia y reanimacion, 2020, Volume: 67, Issue:3

    Topics: Adolescent; Anesthetics, Intravenous; Anesthetics, Local; Child; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Nerve Block; Pain, Postoperative; Paraspinal Muscles; Propofol; Ropivacaine; Scoliosis

2020
Effects of local dexmedetomidine administration on the neurotoxicity of ropivacaine for sciatic nerve block in rats.
    Molecular medicine reports, 2020, Volume: 22, Issue:5

    Topics: Animals; Apoptosis; Autonomic Nerve Block; Caspase 3; Chemotherapy, Adjuvant; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Male; Neurotoxicity Syndromes; Rats; Ropivacaine; Sciatic Nerve

2020
Dual adjunct therapy with dexamethasone and dexmedetomidine in transversus abdominis plane blocks reduces postoperative opioid use in colorectal surgery.
    American journal of surgery, 2021, Volume: 222, Issue:1

    Topics: Abdominal Muscles; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Colectomy; Dexamethasone; Dexmedetomidine; Drug Utilization; Female; Humans; Male; Middle Aged; Nerve Block; Pain Management; Pain Measurement; Pain, Postoperative; Perioperative Care; Postoperative Period; Retrospective Studies; Ropivacaine; Treatment Outcome

2021
Application of dexmedetomidine combined with ropivacaine in axillary brachial plexus block in children and its effect on inflammatory factors.
    Cellular and molecular biology (Noisy-le-Grand, France), 2020, Jul-31, Volume: 66, Issue:5

    Topics: Anesthetics, Local; Arterial Pressure; Brachial Plexus Block; Child; Dexmedetomidine; Female; Heart Rate; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Male; Pain Measurement; Ropivacaine; Tumor Necrosis Factor-alpha

2020
Perineural Dexmedetomidine Reduces the Median Effective Concentration of Ropivacaine for Adductor Canal Block.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Mar-17, Volume: 27

    Topics: Aged; Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; China; Dexmedetomidine; Female; Femoral Nerve; Humans; Knee Joint; Male; Middle Aged; Nerve Block; Pain Management; Pain Measurement; Quadriceps Muscle; Ropivacaine; Thigh

2021
Obesity decreases the EC50 of epidural ropivacaine when combined with dexmedetomidine for labor analgesia.
    Expert review of clinical pharmacology, 2021, Volume: 14, Issue:8

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Female; Humans; Labor Pain; Labor, Obstetric; Obesity; Pain Measurement; Pregnancy; Ropivacaine

2021
Effects of perineural administration of ropivacaine combined with perineural or intravenous administration of dexmedetomidine for sciatic and saphenous nerve blocks in dogs.
    American journal of veterinary research, 2021, Volume: 82, Issue:6

    Topics: Administration, Intravenous; Anesthetics, Local; Animals; Dexmedetomidine; Dogs; Nerve Block; Ropivacaine; Sciatic Nerve

2021
Effect of Dexmedetomidine Combined with Ropivacaine on Cognitive Dysfunction and Inflammatory Response in Patients Undergoing Craniocerebral Surgery.
    BioMed research international, 2021, Volume: 2021

    Topics: Analgesics; Anesthesia; Cognitive Dysfunction; Dexmedetomidine; Female; Heart Rate; Humans; Inflammation; Male; Middle Aged; Oxygen Saturation; Pain Measurement; Ropivacaine

2021
Computerized Tomography Image Features under the Reconstruction Algorithm in the Evaluation of the Effect of Ropivacaine Combined with Dexamethasone and Dexmedetomidine on Assisted Thoracoscopic Lobectomy.
    Journal of healthcare engineering, 2021, Volume: 2021

    Topics: Algorithms; Dexamethasone; Dexmedetomidine; Humans; Ropivacaine; Tomography; Tomography, X-Ray Computed

2021
The strong rationale for the use of dexmedetomidine instead of fentanyl as adjuvant to ropivacaine for epidural anaesthesia.
    International journal of clinical practice, 2021, Volume: 75, Issue:12

    Topics: Anesthesia, Epidural; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Ropivacaine

2021
Efficacy of dexmedetomidine as an adjunct to ropivacaine in bilateral dual-transversus abdominis plane blocks in patients with ovarian cancer who underwent cytoreductive surgery.
    BMC anesthesiology, 2022, 01-12, Volume: 22, Issue:1

    Topics: Abdominal Muscles; Adult; Aged; Anesthetics, Local; Cytoreduction Surgical Procedures; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Nerve Block; Ovarian Neoplasms; Pain, Postoperative; Ropivacaine; Treatment Outcome

2022
Different Doses of Ropivacaine either with Sufentanil or with Dexmedetomidine for Labor Epidural Anesthesia regarding Painless Childbirth: A Retrospective, Multicenter Study.
    Pharmacology, 2022, Volume: 107, Issue:7-8

    Topics: Amides; Analgesia, Epidural; Analgesics; Anesthesia, Epidural; Anesthetics, Local; Bradycardia; Cesarean Section; Child; Dexmedetomidine; Double-Blind Method; Female; Humans; Infant, Newborn; Labor, Obstetric; Pregnancy; Retrospective Studies; Ropivacaine; Sufentanil

2022
The feasibility and safety of cocktail treatment of triple anti-inflammatory agents loaded with gelatin sponge promotes early recovery after posterior percutaneous endoscopic cervical discectomy.
    Journal of orthopaedic surgery and research, 2022, May-26, Volume: 17, Issue:1

    Topics: Anti-Inflammatory Agents; Cervical Vertebrae; Dexamethasone; Dexmedetomidine; Diskectomy; Feasibility Studies; Gelatin; Humans; Pain; Retrospective Studies; Ropivacaine; Treatment Outcome; Vitamin B 12

2022
Dexmedetomidine pretreatment alleviates ropivacaine-induced neurotoxicity via the miR-10b-5p/BDNF axis.
    BMC anesthesiology, 2022, 09-26, Volume: 22, Issue:1

    Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Dexmedetomidine; Humans; Lactate Dehydrogenases; Mice; MicroRNAs; Neuroblastoma; Neuroprotective Agents; Ropivacaine

2022
Postoperative analgesic effect of dexmedetomidine combined with TPVB applied to open gastrectomy for gastric cancer.
    Immunopharmacology and immunotoxicology, 2023, Volume: 45, Issue:2

    Topics: Analgesics; Anesthetics, Local; Dexmedetomidine; Gastrectomy; Humans; Nerve Block; Pain, Postoperative; Ropivacaine; Stomach Neoplasms

2023
Dexmedetomidine protects against Ropivacaine-induced neuronal pyroptosis via the Nrf2/HO-1 pathway.
    The Journal of toxicological sciences, 2023, Volume: 48, Issue:3

    Topics: Cell Line, Tumor; Dexmedetomidine; Heme Oxygenase-1; Humans; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Ropivacaine

2023
Dexamethasone and dexmedetomidine together as adjuvants of ropivacaine 0.15% for a brachial plexus block lasting 20 hours.
    Minerva anestesiologica, 2023, Volume: 89, Issue:11

    Topics: Adjuvants, Pharmaceutic; Anesthetics, Local; Brachial Plexus Block; Dexamethasone; Dexmedetomidine; Humans; Ropivacaine

2023
Local vasoconstriction following ropivacaine/dexmedetomidine parasternal block in a neonate.
    Paediatric anaesthesia, 2023, Volume: 33, Issue:12

    Topics: Amides; Anesthetics, Local; Dexmedetomidine; Humans; Infant, Newborn; Ropivacaine; Vasoconstriction

2023