ropitoin hydrochloride has been researched along with phenytoin in 5 studies
*Phenytoin: An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs. [MeSH]
*Phenytoin: An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanchez-Chapula, J; Valenzuela, C | 1 |
| Elizalde, A; Sanchéz-Chapula, J | 1 |
| Lucchesi, BR; Lynch, J; Montgomery, D; Ventura, A; Wilber, D | 1 |
| Gonzalez-Jasso, E; Hong, E; Peon, J | 1 |
| Hong, E; Mena, MA; Vidrio, H | 1 |
5 other study(ies) available for ropitoin hydrochloride and phenytoin
| Article | Year |
|---|---|
Electrophysiologic interactions between mexiletine-quinidine and mexiletine-ropitoin in guinea pig papillary muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Drug Interactions; Electric Stimulation; Electrophysiology; Female; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Mexiletine; Papillary Muscles; Phenytoin; Quinidine; Temperature | 1989 |
Effects of the novel antiarrhythmic compound TR 2985 (ropitoin) on action potentials of different mammalian cardiac tissues.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Guinea Pigs; Heart; In Vitro Techniques; Papillary Muscles; Phenytoin; Purkinje Fibers | 1988 |
Antiarrhythmic vs. antifibrillatory activity of the basic diphenylhydantoin derivative 3-[3-(4-phenyl-1-piperidyl)propyl]-5-(4-methoxyphenyl)-5-phenylhydantoin hydrochloride.
Topics: Anesthesia, General; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Dogs; Electric Stimulation; Electrocardiography; Heart Ventricles; Male; Myocardial Infarction; Phenytoin; Tachycardia | 1986 |
Antiarrhythmic activity of ropitoin in rats subjected to coronary artery ligation.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Ligation; Phenytoin; Rats | 1986 |
Antiarrhythmic activity of TR 2985, a novel diphenylhydantoin derivative.
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anura; Coronary Vessels; Dogs; Electric Stimulation; Female; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Lidocaine; Male; Mice; Ouabain; Phenytoin; Propranolol; Quinidine | 1980 |