Page last updated: 2024-08-24

rolofylline and 1,3-dipropyl-8-cyclopentylxanthine

rolofylline has been researched along with 1,3-dipropyl-8-cyclopentylxanthine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (69.23)18.2507
2000's3 (23.08)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ichikawa, S; Ishii, A; Nonaka, H; Ono, E; Shimada, J; Shiozaki, S; Suzuki, F1
Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F1
Ishii, A; Nonaka, H; Shimada, J; Suzuki, F1
Jacobson, KA; van Galen, PJ; Williams, M1
Baker, SP; Belardinelli, L; Lee, G; Linden, J; Lum, RT; Milner, P; Pfister, JR; Schreiner, G; Stanley, WC1
Bondavalli, F; Botta, M; Bruno, O; Ciacci, A; Corelli, F; Fossa, P; Lucacchini, A; Manetti, F; Martini, C; Menozzi, G; Mosti, L; Ranise, A; Schenone, S; Tafi, A; Trincavellic, ML1
El-Tayeb, A; Inamdar, GS; Li, W; Müller, CE; Scheiff, AB; Sudarsanam, V; Vasu, KK; Yerande, SG1
Batuman, V; Cai, H; Guan, S; Puschett, DB; Puschett, JB1
Karasawa, A; Mizumoto, H1
Brause, M; Delabar, U; Eckardt, KU; Gleiter, CH; Zebski, H1
Habu, Y; Hashimoto, Y; Inui, K; Katsura, T; Nagai, J; Yano, I1
Dubey, RK; Forman, MB; Jackson, EK; Murray, JJ; Velasco, CE; Vitola, JV1
Diekmann, M; Fülle, F; Hinz, S; Klotz, KN; Müller, CE; Schumacher, B; Weyler, S1

Reviews

1 review(s) available for rolofylline and 1,3-dipropyl-8-cyclopentylxanthine

ArticleYear
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship

1992

Other Studies

12 other study(ies) available for rolofylline and 1,3-dipropyl-8-cyclopentylxanthine

ArticleYear
7,8-Dihydro-8-ethyl-2-(3-noradamantyl)-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one: a potent and water-soluble adenosine A1 antagonist.
    Journal of medicinal chemistry, 1992, Sep-18, Volume: 35, Issue:19

    Topics: Adamantane; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hemodynamics; Imidazoles; Purinergic Antagonists; Purinones; Rats; Receptors, Purinergic; Solubility; Vasodilator Agents

1992
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.
    Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16

    Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines

1992
8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors.
    Journal of medicinal chemistry, 1992, Mar-06, Volume: 35, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; Corpus Striatum; Guinea Pigs; Humans; Molecular Conformation; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Receptors, Purinergic; Stereoisomerism; Structure-Activity Relationship; Xanthines

1992
Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine.
    Journal of medicinal chemistry, 1997, Jun-06, Volume: 40, Issue:12

    Topics: Animals; Diuresis; Guinea Pigs; Humans; Models, Molecular; Molecular Structure; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Xanthines

1997
Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.
    Journal of medicinal chemistry, 2002, Oct-24, Volume: 45, Issue:22

    Topics: Animals; Binding, Competitive; Cattle; Cerebral Cortex; Ligands; Models, Molecular; Purinergic P1 Receptor Antagonists; Pyridines; Radioligand Assay; Receptors, Purinergic P1; Structure-Activity Relationship

2002
2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Adenosine A1 Receptor Antagonists; Animals; Drug Design; Humans; Molecular Structure; Rats; Receptor, Adenosine A1; Stereoisomerism; Structure-Activity Relationship; Thiazoles

2010
Phosphate transport inhibition by KW-3902, an adenosine A1 receptor antagonist, is mediated by cyclic adenosine monophosphate.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1995, Volume: 26, Issue:5

    Topics: Animals; Biological Transport; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Female; Kidney Tubules, Proximal; Parathyroid Hormone; Phosphates; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Xanthines

1995
Effects of adenosine A1-agonist and -antagonist on urinary volume and Na excretion in IAP-treated and non-treated rats.
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:2

    Topics: Animals; Diuresis; Diuretics; Glomerular Filtration Rate; Male; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1; Sodium; Virulence Factors, Bordetella; Xanthines

1993
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
    Kidney international, 1997, Volume: 52, Issue:2

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines

1997
Inhibitory effect of KW-3902, an adenosine A(1) receptor antagonist, on p-aminohippurate transport in OK cells.
    Biochimica et biophysica acta, 1999, Jul-15, Volume: 1419, Issue:2

    Topics: Adenosine Deaminase; Animals; Anion Transport Proteins; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cell Line; Ketoglutaric Acids; Kinetics; p-Aminohippuric Acid; Purinergic P1 Receptor Antagonists; Staurosporine; Xanthines

1999
Sustained reduction in myocardial reperfusion injury with an adenosine receptor antagonist: possible role of the neutrophil chemoattractant response.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3

    Topics: Animals; Coronary Circulation; Dogs; Female; Male; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Xanthines

2000
Improving potency, selectivity, and water solubility of adenosine A1 receptor antagonists: xanthines modified at position 3 and related pyrimido[1,2,3-cd]purinediones.
    ChemMedChem, 2006, Volume: 1, Issue:8

    Topics: Adamantane; Adenosine A1 Receptor Antagonists; Animals; Cells, Cultured; Humans; Phosphates; Prodrugs; Rats; Solubility; Structure-Activity Relationship; Water; Xanthine; Xanthines

2006