Page last updated: 2024-08-16

rofecoxib and thromboxane a2

rofecoxib has been researched along with thromboxane a2 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
García Rodríguez, LA; Patrignani, P; Patrono, C1
Vane, JR1
Austin, SC; Cheng, Y; Coffman, TM; FitzGerald, GA; Grosser, T; Koller, BH; Lawson, JA; Rocca, B1
Frankish, H1
Calhoun, BC; Hoeldtke, NJ; Howard, BC; Kovac, CM; Napolitano, PG1
Gately, S; Li, WW1
Fitzgerald, GA1
Byrne, D; McAdam, BF; Morrow, JD; Oates, JA1
de Leon-Casasola, OA; Kotob, F; Lema, MJ1
Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD1
Guo, ZR1
Dogné, JM; Hanson, J; Pratico, D; Supuran, C1
Cerletti, C; Dell'Elba, G; Evangelista, V; Manarini, S; Rotondo, S1
Marwali, MR; Mehta, JL1

Reviews

5 review(s) available for rofecoxib and thromboxane a2

ArticleYear
Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Blood Platelets; Cardiovascular Diseases; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Depression, Chemical; Dinoprostone; Epoprostenol; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Incidence; Intestinal Mucosa; Isoenzymes; Lactones; Membrane Proteins; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Randomized Controlled Trials as Topic; Substrate Specificity; Sulfonamides; Sulfones; Thromboembolism; Thromboxane A2; Treatment Outcome

2001
Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy.
    Seminars in oncology, 2004, Volume: 31, Issue:2 Suppl 7

    Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Celecoxib; Cell Movement; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epidermal Growth Factor; Epoprostenol; Humans; Interleukin-12; Isoenzymes; Lactones; Matrix Metalloproteinases; Membrane Proteins; Neoplasms; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Signal Transduction; Sulfonamides; Sulfones; Thromboxane A2; Vascular Endothelial Growth Factor A

2004
[Innovation of anti-inflammatory drugs--inhibition of cyclooxygenases].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Epoprostenol; Humans; Lactones; Pyrazoles; Sulfonamides; Sulfones; Thromboxane A2

2005
Coxibs and cardiovascular side-effects: from light to shadow.
    Current pharmaceutical design, 2006, Volume: 12, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Epoprostenol; Humans; Isoxazoles; Lactones; Pyrazoles; Structure-Activity Relationship; Sulfonamides; Sulfones; Thromboxane A2

2006
COX-2 inhibitors and cardiovascular risk. Inferences based on biology and clinical studies.
    Thrombosis and haemostasis, 2006, Volume: 96, Issue:4

    Topics: Animals; Blood Platelets; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Labeling; Endothelium, Vascular; Epoprostenol; Humans; Lactones; Platelet Aggregation; Product Surveillance, Postmarketing; Pyrazoles; Randomized Controlled Trials as Topic; Risk Assessment; Sulfonamides; Sulfones; Thromboxane A2

2006

Trials

1 trial(s) available for rofecoxib and thromboxane a2

ArticleYear
Contribution of cyclooxygenase-2 to elevated biosynthesis of thromboxane A2 and prostacyclin in cigarette smokers.
    Circulation, 2005, Aug-16, Volume: 112, Issue:7

    Topics: Adult; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Double-Blind Method; Epoprostenol; Humans; Lactones; Male; Membrane Proteins; Platelet Activation; Prostaglandins; Reference Values; Smoking; Sulfones; Thromboxane A2

2005

Other Studies

8 other study(ies) available for rofecoxib and thromboxane a2

ArticleYear
Biomedicine. Back to an aspirin a day?
    Science (New York, N.Y.), 2002, Apr-19, Volume: 296, Issue:5567

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carotid Artery Injuries; Cell Division; Clinical Trials as Topic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epoprostenol; Homeostasis; Humans; Isoenzymes; Lactones; Membrane Proteins; Mice; Muscle, Smooth, Vascular; Myocardial Infarction; Naproxen; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfones; Thromboxane A2

2002
Role of prostacyclin in the cardiovascular response to thromboxane A2.
    Science (New York, N.Y.), 2002, Apr-19, Volume: 296, Issue:5567

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carotid Artery Injuries; Carotid Artery, Common; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Epoprostenol; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; Naphthalenes; Platelet Activation; Platelet Aggregation; Propionates; Prostaglandin-Endoperoxide Synthases; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfones; Tetrahydronaphthalenes; Thromboxane A2; Tunica Intima

2002
Why do COX-2 inhibitors increase risk of cardiovascular events?
    Lancet (London, England), 2002, Apr-20, Volume: 359, Issue:9315

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Lactones; Membrane Proteins; Mice; Myocardial Infarction; Naproxen; Prostaglandin-Endoperoxide Synthases; Sulfones; Thromboxane A2

2002
The effects of a cyclo-oxygenase II inhibitor on placental artery production of thromboxane and prostacyclin.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:3

    Topics: Angiotensin II; Arteries; Culture Media; Culture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Epoprostenol; Female; Humans; Isoenzymes; Lactones; Membrane Proteins; Placenta; Pregnancy; Prostaglandin-Endoperoxide Synthases; Sulfones; Thromboxane A2

2003
Coxibs and cardiovascular disease.
    The New England journal of medicine, 2004, Oct-21, Volume: 351, Issue:17

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Approval; Drug Industry; Epoprostenol; Gastrointestinal Diseases; Humans; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Naproxen; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Risk; Sulfonamides; Sulfones; Thromboxane A2; United States; United States Food and Drug Administration

2004
NSAIDs and cardiovascular risk.
    Cell metabolism, 2005, Volume: 2, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular System; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hypertension; Lactones; Sulfones; Thromboxane A2

2005
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2

2006
The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit.
    European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3

    Topics: Acetates; Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Electrocardiography; Heart Rate; Inflammation; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; N-Formylmethionine Leucyl-Phenylalanine; Pyrroles; Rabbits; Sulfones; Thromboxane A2; Time Factors

2006