rofecoxib and sc 560
rofecoxib has been researched along with sc 560 in 25 studies
Research
Studies (25)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 18 (72.00) | 29.6817 |
| 2010's | 7 (28.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Blobaum, AL; Crews, BC; Daniel, CM; Ghebreselasie, K; Kingsley, PJ; Liedtke, AJ; Marnett, LJ | 1 |
| Gretzer, B; Maricic, N; Peskar, BM; Respondek, M; Schuligoi, R | 1 |
| Hase, S; Miyazawa, T; Takeuchi, K; Tanaka, A | 1 |
| Campos, MD; Domínguez, R; López-Muñoz, FJ; Martínez, RV; Reval, M; Terrón, JA | 1 |
| Aoi, M; Kagawa, S; Kawauchi, S; Mimaki, H; Takeuchi, K | 1 |
| Hayashi, Y; Matsumoto, M; Miyazawa, T; Takeuchi, K | 1 |
| Hayashi, Y; Murakami, M; Takeeda, M; Takeuchi, K; Yamato, M | 1 |
| Hayashi, Y; Kubo, Y; Takeuchi, K; Tanaka, A | 1 |
| Brzozowski, T; Drozdowicz, D; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Pawlik, WW; Sliwowski, Z | 1 |
| Takahira, Y; Takeuchi, K; Tanaka, A; Taniguchi, M; Yokota, A | 1 |
| Takeuchi, K; Tanaka, A; Taniguchi, M; Yokota, A | 1 |
| Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Egger, T; Ehrlich, K; Peskar, BM; Sattler, W | 1 |
| Nylander, O; Pihl, L | 1 |
| Takahira, Y; Takeuchi, K; Tanaka, A; Yokota, A | 1 |
| Aihara, E; Nakashima, M; Nishio, H; Takeuchi, K; Terashima, S | 1 |
| de Godoy, MA; Rattan, N; Rattan, S | 1 |
| Murakami, M; Nakagiri, A | 1 |
| Akino, H; Aoki, Y; Nagase, K; Tanaka, I; Tanase, K; Yokoyama, O | 1 |
| Amagase, K; Kato, S; Satoh, H; Takeuchi, K; Tanaka, A | 1 |
| Frölich, S; Kern, N; Narumiya, S; Nüsing, RM; Olliges, A; Schreiber, Y | 1 |
| Brzozowski, B; Brzozowski, T; Jasnos, K; Konturek, PC; Konturek, SJ; Kwiecien, S; Magierowski, M; Mitis-Musiol, M; Pawlik, MW; Sliwowski, Z | 1 |
| Jansson, L; Sandberg, M | 1 |
| Brzozowski, T; Czekaj, R; Kwiecien, S; Magierowska, K; Magierowski, M; Majka, J; Pajdo, R; Ptak-Belowska, A; Sliwowski, Z; Surmiak, M | 1 |
Reviews
1 review(s) available for rofecoxib and sc 560
| Article | Year |
|---|---|
Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Indomethacin; Intestine, Small; Lactones; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfones | 2010 |
Other Studies
24 other study(ies) available for rofecoxib and sc 560
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Screening Assays, Antitumor; Female; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Sheep; Stereoisomerism; Structure-Activity Relationship; Sulindac | 2012 |
Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Furans; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Hydrochloric Acid; Indomethacin; Isoenzymes; Lactones; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; RNA, Messenger; Stomach; Sulfones | 2001 |
Up-regulation of cyclooxygenase-2 by inhibition of cyclooxygenase-1: a key to nonsteroidal anti-inflammatory drug-induced intestinal damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enteritis; Intestinal Mucosa; Isoenzymes; Lactones; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones; Up-Regulation | 2002 |
Involvement of peripheral cyclooxygenase-1 and cyclooxygenase-2 in inflammatory pain.
Topics: Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Inflammation; Lactones; Pain; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Sulfones; Uric Acid | 2002 |
COX and NOS isoforms involved in acid-induced duodenal bicarbonate secretion in rats.
Topics: Animals; Bicarbonates; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Duodenum; Guanidines; Indomethacin; Isoenzymes; Lactones; Male; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfones | 2002 |
Both selective COX-1 and COX-2 inhibitors aggravate gastric damage induced in rats by 2-deoxy-D-glucose. relation to gastric hypermotility and COX-2 expression.
Topics: Animals; Cyclooxygenase Inhibitors; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Isoenzymes; Lactones; Male; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfones | 2003 |
Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.
Topics: Administration, Oral; Animals; Body Weight; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Acid; Gastric Mucosa; Gastritis; Gene Expression; Indomethacin; Injections, Subcutaneous; Iodoacetamide; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach Ulcer; Sulfones; Vagotomy | 2004 |
Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs: importance of gastric hypermotility.
Topics: Animals; Atropine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastrointestinal Motility; Indomethacin; Isoenzymes; Lactones; Male; Omeprazole; Peroxidase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stomach; Stomach Ulcer; Sulfones | 2004 |
Ischemic preconditioning of remote organs attenuates gastric ischemia-reperfusion injury through involvement of prostaglandins and sensory nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Dinoprostone; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Sulfones; Tumor Necrosis Factor-alpha | 2004 |
Rofecoxib produces intestinal but not gastric damage in the presence of a low dose of indomethacin in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Colony Count, Microbial; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enterobacteriaceae; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Lactones; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Ulcer; Sulfones | 2005 |
Development of intestinal, but not gastric damage caused by a low dose of indomethacin in the presence of rofecoxib.
Topics: Ampicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrointestinal Motility; Gene Expression; Guanidines; Indomethacin; Intestinal Mucosa; Intestine, Small; Lactones; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stomach; Sulfones | 2005 |
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2 | 2006 |
Dexamethasone impairs the gastric mucosal integrity in rats treated with a cyclooxygenase-1 but not with a cyclooxygenase-2 inhibitor.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Drug Interactions; Drug Therapy, Combination; Gastric Mucosa; Lactones; Male; Pyrazoles; Rats; Rats, Wistar; Sulfones; Time Factors | 2006 |
Products of cyclooxygenase-2 depress duodenal function in rats subjected to abdominal surgery.
Topics: Animals; Bicarbonates; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Duodenum; Gastrointestinal Motility; Intestinal Absorption; Intestinal Mucosa; Isoxazoles; Lactones; Laparotomy; Male; Osmolar Concentration; Perfusion; Pyrazoles; Rats; Rats, Inbred Lew; Sodium Chloride; Sulfones | 2006 |
Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lactones; Male; Naproxen; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfones; Time Factors; Up-Regulation | 2006 |
Involvement of prostaglandin E receptor EP3 subtype and prostacyclin IP receptor in decreased acid response in damaged stomach.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bridged Bicyclo Compounds; Caproates; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Lactones; Male; Membrane Potentials; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrazoles; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Stomach Diseases; Sulfones; Taurocholic Acid | 2007 |
COX-1 vs. COX-2 as a determinant of basal tone in the internal anal sphincter.
Topics: Anal Canal; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Indomethacin; Lactones; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Polymerase Chain Reaction; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; RNA, Messenger; Sulfones | 2009 |
Roles of NADPH oxidase in occurrence of gastric damage and expression of cyclooxygenase-2 during ischemia/reperfusion in rat stomachs.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Gastric Mucosa; Hydrogen Peroxide; Indomethacin; Ischemia; Lactones; Male; NADPH Oxidases; Onium Compounds; Peroxidase; Pyrazoles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfones; Up-Regulation | 2009 |
Improvement in neurogenic detrusor overactivity by peripheral C fiber's suppression with cyclooxygenase inhibitors.
Topics: Animals; Cerebral Infarction; Cyclooxygenase Inhibitors; Female; Lactones; Nerve Fibers, Unmyelinated; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfones; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2010 |
Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Intramolecular Oxidoreductases; Kidney; Lactones; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Prostaglandin-E Synthases; Pyrazoles; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfones; Time Factors | 2012 |
Interaction between selective cyclooxygenase inhibitors and capsaicin-sensitive afferent sensory nerves in pathogenesis of stress-induced gastric lesions. Role of oxidative stress.
Topics: Aldehydes; Animals; Capsaicin; Cyclooxygenase Inhibitors; Gastric Mucosa; Glutathione; Lactones; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; Sensory Receptor Cells; Stress, Psychological; Sulfones; Superoxide Dismutase | 2012 |
Effects of cyclooxygenase inhibition on insulin release and pancreatic islet blood flow in rats.
Topics: Animals; Blood Flow Velocity; Blood Glucose; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Duodenum; Glucose; Indomethacin; Insulin; Islets of Langerhans; Lactones; Male; Membrane Proteins; Piperazines; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; Sulfones; Thiazoles | 2014 |
Mechanisms of curcumin-induced gastroprotection against ethanol-induced gastric mucosal lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; CDX2 Transcription Factor; Curcumin; Cyclooxygenase 2 Inhibitors; Denervation; Down-Regulation; Ethanol; Female; Gastric Mucosa; Gastrins; Gene Expression; Heme Oxygenase (Decyclizing); Hypoxia-Inducible Factor 1, alpha Subunit; Indomethacin; Lactones; Male; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; RNA, Messenger; Stomach Diseases; Sulfones; Superoxide Dismutase; TRPV Cation Channels; Up-Regulation | 2018 |