rofecoxib and morphine
rofecoxib has been researched along with morphine in 23 studies
Research
Studies (23)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 20 (86.96) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Connelly, NR; Reuben, SS | 1 |
| Andriole, GL; Hsu, H; Huang, JJ; Kurz, A; Taguchi, A | 1 |
| Meyer, R | 1 |
| Déciga-Campos, M; López, UG; López-Muñoz, FJ; Reval, MI | 1 |
| Akyürek, C; Celik, C; Celik, JB; Reisli, R; Sarkilar, G; Tuncer, S | 1 |
| Halaszynski, T; Luther, MA; Shaheen, Y; Shen, QJ; Sinatra, RS | 1 |
| Baumann, PC; Bombeli, T; Haller, U; Hegi, TR; Pasch, T; Seifert, B; Spahn, DR; Zalunardo, MP | 1 |
| An, HY; Feng, Y; Ju, H; Yang, BX; Zhou, YY | 1 |
| Cabrera, MC; Derderian, T; Santelices, E; Schmied, S; Vega, R; Verdugo, F; White, PF | 1 |
| Bell, AC; Gilron, I; O'Neill, JP; Orr, E; Tu, D; Zamora, JE | 1 |
| Ackermann, DK; Engeler, DS; Keel, A; Osterwalder, JJ; Schmid, HP | 1 |
| Beiderlinden, M; Eikermann, M; Hoffmann, O; Neuhäuser, M; Peters, J; Pospiech, J; Riest, G; Weiss, M | 1 |
| Andersen, PJ; Dahl, JB; Enggaard, TP; Hansen, M; Henriksen, J; Hilsted, KL; Hjortsø, NC; Jørgensen, DG; Mikkelsen, S | 1 |
| Alleyne, CH; French, A; Macomson, SD; Rahimi, SY; Smith, JR; Vender, JR | 1 |
| Boscariol, R; Gilron, I; Orr, E | 1 |
| Carignan, M; Dorion, D; Lafrenaye, S; Vallée, E | 1 |
| Angeby-Möller, K; Berge, OG; Hamers, FP | 1 |
| Betnér, I; Briem, S; Bueters, T; Dahlström, J; Kvalvågnaes, K | 1 |
Trials
14 trial(s) available for rofecoxib and morphine
| Article | Year |
|---|---|
Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Enzyme Inhibitors; Humans; Lactones; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Premedication; Pyrazoles; Spinal Fusion; Sulfonamides; Sulfones | 2000 |
Preoperative oral rofecoxib does not decrease postoperative pain or morphine consumption in patients after radical prostatectomy: a prospective, randomized, double-blinded, placebo-controlled trial.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Prostatectomy; Sulfones | 2001 |
A comparative study of the effect of rofecoxib (a COX 2 inhibitor) and naproxen sodium on analgesic requirements after abdominal hysterectomy.
Topics: Adult; Analgesia; Cyclooxygenase Inhibitors; Dyspepsia; Female; Gastrointestinal Diseases; Heartburn; Humans; Hysterectomy; Lactones; Middle Aged; Morphine; Naproxen; Placebos; Postoperative Nausea and Vomiting; Premedication; Sulfones | 2003 |
Preoperative rofecoxib oral suspension as an analgesic adjunct after lower abdominal surgery: the effects on effort-dependent pain and pulmonary function.
Topics: Abdomen; Aged; Analgesics, Opioid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Forced Expiratory Flow Rates; Humans; Intraoperative Care; Isoenzymes; Lactones; Lung; Male; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Period; Premedication; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Respiratory Mechanics; Spirometry; Sulfones; Suspensions; Vital Capacity | 2004 |
Effect of rofecoxib on platelet aggregation and blood loss in gynaecological and breast surgery compared with diclofenac.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Blood Loss, Surgical; Breast Neoplasms; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Hemostasis, Surgical; Humans; Hysterectomy; Lactones; Middle Aged; Morphine; Pain Measurement; Platelet Aggregation; Pregnancy; Prospective Studies; Sulfones; Treatment Outcome | 2004 |
[Postoperative analgesic and anti-inflammatory effects of rofecoxib after total knee replacement].
Topics: Administration, Oral; Aged; Analgesia, Epidural; Anti-Inflammatory Agents; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Lactones; Male; Middle Aged; Morphine; Pain, Postoperative; Premedication; Sulfones | 2004 |
Efficacy of oral rofecoxib versus intravenous ketoprofen as an adjuvant to PCA morphine after urologic surgery.
Topics: Administration, Oral; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Spinal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Costs; Humans; Injections, Intravenous; Isoenzymes; Ketoprofen; Lactones; Male; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases; Sulfones; Urologic Surgical Procedures, Male | 2004 |
A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy.
Topics: Adult; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lactones; Male; Middle Aged; Morphine; Movement; Pain Measurement; Pain, Postoperative; Retrospective Studies; Sulfones; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2005 |
A double-blind, placebo controlled comparison of the morphine sparing effect of oral rofecoxib and diclofenac for acute renal colic.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Kidney Diseases; Lactones; Male; Middle Aged; Morphine; Multivariate Analysis; Pain Measurement; Sulfones | 2005 |
Does perioperative administration of rofecoxib improve analgesia after spine, breast and orthopaedic surgery?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Breast; Cyclooxygenase 2 Inhibitors; Diskectomy; Double-Blind Method; Female; Humans; Lactones; Male; Mastectomy; Middle Aged; Morphine; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Perioperative Care; Spine; Sulfones | 2006 |
The effect of gabapentin on post-operative pain following tonsillectomy in adults.
Topics: Adolescent; Adult; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lactones; Male; Meperidine; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Sulfones; Tonsillectomy | 2006 |
Postoperative pain management after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Craniotomy; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hospital Costs; Humans; Injections, Intravenous; Lactones; Length of Stay; Male; Middle Aged; Morphine; Narcotics; Oxycodone; Pain Measurement; Pain, Postoperative; Single-Blind Method; Sulfones; Treatment Outcome | 2006 |
Chronobiological characteristics of postoperative pain: diurnal variation of both static and dynamic pain and effects of analgesic therapy.
Topics: Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Circadian Rhythm; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lactones; Morphine; Pain Measurement; Pain, Postoperative; Single-Blind Method; Sulfones; Time Factors | 2007 |
Comparative study of acetaminophen-morphine versus rofecoxib-morphine for post-tonsillectomy pain control.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Lactones; Male; Morphine; Pain Measurement; Pain, Postoperative; Sulfones; Tonsillectomy | 2007 |
Other Studies
9 other study(ies) available for rofecoxib and morphine
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
[Cox-2 inhibitors in the focus. Rofecoxib as effective as the "classics"].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Humans; Lactones; Morphine; Pain, Postoperative; Pyrazoles; Risk Factors; Spinal Fusion; Sulfonamides; Sulfones; Time Factors | 2001 |
Rofecoxib reduces perioperative morphine consumption for abdominal hysterectomy and laparoscopic gastric banding.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Interactions; Female; Gastroplasty; Humans; Hysterectomy; Lactones; Laparoscopy; Morphine; Pain Measurement; Pain, Postoperative; Preoperative Care; Prognosis; Retrospective Studies; Sulfones | 2002 |
[Rofecoxib in surgical pain. Saving morphine!].
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Lactones; Morphine; Pain Measurement; Pain, Postoperative; Premedication; Sulfones | 2002 |
Enhancement of antinociception by co-administration of an opioid drug (morphine) and a preferential cyclooxygenase-2 inhibitor (rofecoxib) in rats.
Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Arthralgia; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Isoenzymes; Lactones; Male; Morphine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach; Stomach Ulcer; Sulfones; Time Factors; Uric Acid | 2003 |
Using the CatWalk method to assess weight-bearing and pain behaviour in walking rats with ankle joint monoarthritis induced by carrageenan: effects of morphine and rofecoxib.
Topics: Analgesics; Analgesics, Opioid; Animals; Ankle Joint; Anti-Inflammatory Agents; Arthralgia; Arthritis; Behavior, Animal; Biomechanical Phenomena; Carrageenan; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Inflammation Mediators; Lactones; Lameness, Animal; Male; Morphine; Pain Measurement; Pattern Recognition, Automated; Rats; Rats, Sprague-Dawley; Sulfones; Treatment Outcome; Video Recording; Walking; Weight-Bearing | 2008 |
High-throughput analysis of standardized pharmacokinetic studies in the rat using sample pooling and UPLC-MS/MS.
Topics: Administration, Oral; Animals; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Diclofenac; Ions; Lactones; Male; Mass Spectrometry; Morphine; Phenytoin; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sulfones | 2011 |