rofecoxib and mobic
rofecoxib has been researched along with mobic in 44 studies
Research
Studies (44)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (9.09) | 18.2507 |
| 2000's | 31 (70.45) | 29.6817 |
| 2010's | 9 (20.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Brideau, C; Chan, CC; Charleson, S; Cromlish, W; Ethier, D; Evans, JF; Ford-Hutchinson, AW; Gauthier, JY; Gordon, R; Gresser, M; Guay, J; Kargman, S; Kennedy, B; Leblanc, Y; Léger, S; Mancini, J; O'Neill, GP; Ouellet, M; Percival, MD; Perrier, H; Prasit, P; Riendeau, D; Rodger, I; Wang, Z; Zamboni, R | 1 |
| Byun, Y; Choi, JK; Choi, YH; Chung, S; Jeong, YS; Kim, JK; Kim, JY; Koh, HJ; Lee, KW; Lim, KM; Moh, JH; Noh, MS; Oh, YI; Park, YH; Shin, SS | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Houben, JJ; Liem, B | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Sliwowski, Z; Stachura, J | 1 |
| Brater, DC | 1 |
| Hawkey, CJ; Jackson, LM | 1 |
| Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K | 1 |
| Frölich, JC; Stichtenoth, DO | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Ptak, A; Sliwowski, Z | 1 |
| Mejza, F; Nizankowska, E | 1 |
| Swaak, AJ; Theunissen, DJ | 1 |
| Capriotti, T | 1 |
| Hawkey, CJ | 1 |
| Lane, S; Linley, W; Maskrey, N; McQuade, C; Micklewright, R; Thompson, F | 1 |
| Devière, J | 1 |
| Heeley, E; Hughes, K; Layton, D; Shakir, SA | 2 |
| Burke, TA; Goldstein, JL; MacDonald, TM; Morant, SV; Pettitt, D | 1 |
| Bhatia, S; Seedher, N | 1 |
| Bavbek, S; Celik, G; Misirligil, Z; Mungan, D; Ozer, F | 1 |
| Degner, F; Lesaffre, E; Zeidler, H | 1 |
| Chem, YC; Cheng, TT; Chiu, CK; Lai, HM | 1 |
| Antonicelli, L; Bilò, MB; Bonadonna, P; Crivellaro, MA; Dama, AR; Schiappoli, M; Senna, G | 1 |
| Dahlborg, R; Day, CA; Jacob, RF; Mason, RP; Walter, MF; Weng, Y | 1 |
| Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Hsiao, FY; Huang, WF; Shih, YT; Tsai, YW; Wen, YW | 1 |
| Adelsberg, JV; Bolognese, JA; Cavanaugh, P; Chen, PY; Giannini, EH; Goodman, S; Kiss, MH; Lovell, DJ; Reicin, AS; Reiff, A; Zavaler, MF | 1 |
| Cağici, CA; Calişkan, EE; Erkan, AN; Gencay, S; Ozlüoğlu, LN; Sener, M; Yavuz, H; Yilmaz, I; Yilmazer, C | 1 |
| Chen, SH; Hsieh, YH; Lin, SJ | 1 |
| Dudhgaonkar, SP; Kumar, D; Naik, AK; Raviprakash, V; Tandan, SK | 1 |
| Aghazadeh-Habashi, A; Harirforoosh, S; Jamali, F | 1 |
| Boursinos, L; Karachalios, T; Khaldi, L; Malizos, KN; Poultsides, L | 1 |
| Chantler, I; Fuller, A; Mitchell, D | 1 |
| Harirforoosh, S; Jamali, F | 1 |
| Alfieri, AB; Linares-Fernández, B | 1 |
| Kumar, A; Kumar, P; Kumari, B | 1 |
| Barozzi, N; Peeters, GM; Tett, SE | 1 |
| Matteson, EL; Thongprayoon, C; Ungprasert, P | 1 |
| Choi, HK; Dalal, DS; Dubreuil, M; Felson, DT; Lee, T; Lu, N; Zhang, Y | 1 |
| Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM | 1 |
| Aghazadeh-Habashi, A; Asghar, W; Jamali, F | 1 |
| Borges, A; Casoti, R; da Cunha, NL; da Rocha Pissurno, AP; da Silva de Laurentiz, R; E Silva, MLA; Kawano, DF | 1 |
Reviews
10 review(s) available for rofecoxib and mobic
| Article | Year |
|---|---|
Effects of nonsteroidal anti-inflammatory drugs on renal function: focus on cyclooxygenase-2-selective inhibition.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Kidney; Lactones; Meloxicam; Membrane Proteins; Nabumetone; Natriuresis; Nephritis, Interstitial; Potassium; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Renal Circulation; Sodium; Sulfonamides; Sulfones; Thiazines; Thiazoles | 1999 |
COX-2 selective nonsteroidal anti-Inflammatory drugs: do they really offer any advantages?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Etodolac; Humans; Lactones; Meloxicam; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2000 |
[Therapy with preferential and specific COX-2 inhibitors].
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Pain; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2001 |
[Selective cyclooxygenase 2 inhibitors (COX-2)].
Topics: Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inflammation; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2001 |
The new NSAIDs: cox-2 inhibitors.
Topics: Advertising; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Industry; Gastrointestinal Diseases; Humans; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Safety; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2000 |
Cyclooxygenase inhibition: between the devil and the deep blue sea.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastroscopy; Humans; Isoenzymes; Kidney; Lactones; Meloxicam; Membrane Proteins; Myocardial Infarction; Prostaglandin-Endoperoxide Synthases; Proton Pump Inhibitors; Pyrazoles; Randomized Controlled Trials as Topic; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2002 |
Review article: NSAIDs, gastroprotection and cyclo-oxygenase-II-selective inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Practice Guidelines as Topic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2003 |
Do selective cyclo-oxygenase inhibitors eliminate the adverse events associated with nonsteroidal anti-inflammatory drug therapy?
Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Meloxicam; Neoplasms; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2002 |
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprofen; Incidence; Indomethacin; Lactones; Meloxicam; Naproxen; Observational Studies as Topic; Odds Ratio; Piroxicam; Proportional Hazards Models; Stroke; Sulfones; Thiazines; Thiazoles | 2016 |
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Celecoxib; Child; Child, Preschool; Chronic Disease; Chronic Pain; Fenoprofen; Humans; Ibuprofen; Lactones; Meloxicam; Methoxsalen; Naproxen; Randomized Controlled Trials as Topic; Sulfones; Thiazines; Thiazoles | 2017 |
Trials
7 trial(s) available for rofecoxib and mobic
| Article | Year |
|---|---|
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2 | 2000 |
Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Immunologic Tests; Lactones; Male; Meloxicam; Middle Aged; Single-Blind Method; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome; Urticaria | 2004 |
A single-blind, randomized, controlled trial to assess the efficacy and tolerability of rofecoxib, diclofenac sodium, and meloxicam in patients with acute gouty arthritis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Diclofenac; Female; Humans; Lactones; Male; Meloxicam; Middle Aged; Single-Blind Method; Sulfones; Thiazines; Thiazoles | 2004 |
Tolerability of three selective cyclo-oxygenase-2 inhibitors, meloxicam, celecoxib and rofecoxib in NSAID-sensitive patients.
Topics: Adolescent; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cross Reactions; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Forced Expiratory Volume; Hemodynamics; Humans; Isoenzymes; Lactones; Male; Meloxicam; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Recurrence; Rhinitis, Allergic, Perennial; Single-Blind Method; Sulfonamides; Sulfones; Thiazines; Thiazoles; Urticaria | 2004 |
Evaluation of the comparative efficacy and tolerability of rofecoxib and naproxen in children and adolescents with juvenile rheumatoid arthritis: a 12-week randomized controlled clinical trial with a 52-week open-label extension.
Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Lactones; Longitudinal Studies; Male; Meloxicam; Naproxen; Sulfones; Thiazines; Thiazoles; Treatment Outcome | 2006 |
[Postoperative pain management in clinics of otolaryngology].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Dipyrone; Etodolac; Female; Humans; Lactones; Male; Meloxicam; Middle Aged; Naproxen; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Postoperative Period; Sulfones; Thiazines; Thiazoles; Treatment Outcome | 2006 |
The effect of three cyclo-oxygenase inhibitors on intensity of primary dysmenorrheic pain.
Topics: Adult; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Dysmenorrhea; Female; Humans; Lactones; Meloxicam; Pain Measurement; Self Medication; Sulfones; Thiazines; Thiazoles | 2008 |
Other Studies
27 other study(ies) available for rofecoxib and mobic
| Article | Year |
|---|---|
The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor.
Topics: Administration, Oral; Animals; Biological Availability; CHO Cells; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Sulfones | 1999 |
In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives.
Topics: Adult; Animals; Arthritis, Experimental; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Furans; Humans; In Vitro Techniques; Isoenzymes; Macrophages, Peritoneal; Male; Membrane Proteins; Mice; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Effectiveness, safety, and costs of measures for prevention of gastropathy due to the use of nonsteroidal antiinflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Clinical Trials as Topic; Confounding Factors, Epidemiologic; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Humans; Lactones; Meloxicam; Nabumetone; Pyrazoles; Stomach Diseases; Sulfonamides; Sulfones; Thiazines; Thiazoles | 1999 |
Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Gastric Mucosa; Gastrins; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Time Factors | 1999 |
Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Gastrins; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Male; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
[Safety of specific cyclo-oxygenase 2 inhibitors].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Gastritis; Humans; Lactones; Meloxicam; Netherlands; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2001 |
Comparison of the incidence rates of selected gastrointestinal events reported for patients prescribed rofecoxib and meloxicam in general practice in England using prescription-event monitoring data.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Prescriptions; England; Family Practice; Female; Gastrointestinal Diseases; Humans; Incidence; Isoenzymes; Lactones; Male; Meloxicam; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Sex Factors; Sulfones; Thiazines; Thiazoles | 2003 |
Comparison of the incidence rates of thromboembolic events reported for patients prescribed rofecoxib and meloxicam in general practice in England using prescription-event monitoring (PEM) data.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chi-Square Distribution; Cohort Studies; Cyclooxygenase Inhibitors; England; Family Practice; Female; Humans; Incidence; Lactones; Male; Meloxicam; Middle Aged; Osteoarthritis; Risk Factors; Sulfones; Survival Analysis; Thiazines; Thiazoles; Thromboembolism | 2003 |
Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bias; Celecoxib; Cohort Studies; Databases, Factual; Family Practice; Female; Gastrointestinal Hemorrhage; Humans; Lactones; Male; Meloxicam; Middle Aged; Pyrazoles; Risk Factors; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2003 |
Solubility enhancement of Cox-2 inhibitors using various solvent systems.
Topics: Celecoxib; Chemistry, Pharmaceutical; Cyclooxygenase 2; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoenzymes; Lactones; Meloxicam; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Solubility; Solvents; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2003 |
Re: Layton et al. Comparison of the incidence rates of selected gastrointestinal events reported for patients prescribed rofecoxib and meloxicam in general practice in England using prescription-event monitoring data.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Bias; Gastrointestinal Diseases; Humans; Lactones; Meloxicam; Sulfones; Thiazines; Thiazoles | 2004 |
Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs.
Topics: Animals; Antioxidants; Celecoxib; Cholesterol, LDL; Chromans; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Isoprostanes; Isoxazoles; Lactones; Meloxicam; Naproxen; Oxidation-Reduction; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2004 |
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2 | 2006 |
Cardiovascular events associated with long-term use of celecoxib, rofecoxib and meloxicam in Taiwan: an observational study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Angina Pectoris; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Databases, Factual; Female; Humans; Insurance, Pharmaceutical Services; Ischemic Attack, Transient; Lactones; Male; Meloxicam; Middle Aged; Myocardial Infarction; National Health Programs; Proportional Hazards Models; Pyrazoles; Risk Assessment; Stroke; Sulfonamides; Sulfones; Taiwan; Thiazines; Thiazoles; Time Factors | 2006 |
Simultaneous determination of celecoxib, meloxicam, and rofecoxib using capillary electrophoresis with surfactant and application in drug formulations.
Topics: Celecoxib; Chemistry, Pharmaceutical; Cyclooxygenase 2 Inhibitors; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Lactones; Meloxicam; Molecular Structure; Pyrazoles; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Sulfones; Surface-Active Agents; Thiazines; Thiazoles | 2006 |
Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
Topics: Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Guanidines; Hyperalgesia; Lactones; Male; Meloxicam; Neuralgia; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase Type II; Nociceptors; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Reaction Time; Sciatic Neuropathy; Sulfones; Thiazines; Thiazoles; Treatment Outcome | 2007 |
Extent of renal effect of cyclo-oxygenase-2-selective inhibitors is pharmacokinetic dependent.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Kidney; Lactones; Male; Meloxicam; Placebos; Potassium; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2006 |
The effects of the short-term administration of low therapeutic doses of anti-COX-2 agents on the healing of fractures. An experimental study in rabbits.
Topics: Analysis of Variance; Animals; Bony Callus; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Fracture Healing; Fractures, Bone; Indomethacin; Lactones; Male; Meloxicam; Prednisolone; Rabbits; Sulfones; Thiazines; Thiazoles | 2007 |
Effect of inflammation on kidney function and pharmacokinetics of COX-2 selective nonsteroidal anti-inflammatory drugs rofecoxib and meloxicam.
Topics: Administration, Oral; Animals; Area Under Curve; Arthritis, Experimental; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Kidney; Kidney Function Tests; Lactones; Male; Meloxicam; Rats; Rats, Sprague-Dawley; Sulfones; Thiazines; Thiazoles | 2008 |
[Changes in nitric oxide, prostaglandins and myeloperoxidase activity in acrolein-induced cystitis in rats].
Topics: Acrolein; Androstanes; Animals; Benzimidazoles; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystitis; Dinoprostone; Drug Evaluation, Preclinical; Lactones; Male; Meloxicam; Membrane Proteins; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfones; Thiazines; Thiazoles; Urinary Bladder | 2009 |
Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress.
Topics: Animals; Anxiety; Catalase; Chronic Disease; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Glutathione; Isoxazoles; Lactones; Lipid Peroxidation; Male; Meloxicam; Memory; Mice; Motor Activity; Naproxen; Nitrites; Random Allocation; Stress, Psychological; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2010 |
Actions following adverse drug events - how do these influence uptake and utilisation of newer and/or similar medications?
Topics: Aged; Australia; Bone Density Conservation Agents; Celecoxib; Cyclooxygenase 2 Inhibitors; Diphosphonates; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lactones; Medication Adherence; Meloxicam; Osteoporosis; Sulfones; Thiazines; Thiazoles | 2015 |
Use of non-steroidal anti-inflammatory drugs correlates with the risk of venous thromboembolism in knee osteoarthritis patients: a UK population-based case-control study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Logistic Models; Male; Meloxicam; Middle Aged; Naproxen; Odds Ratio; Osteoarthritis, Knee; Risk Factors; Sulfones; Thiazines; Thiazoles; Treatment Outcome; United Kingdom; Venous Thromboembolism | 2016 |
Drug-Disease Interaction: Effect of Inflammation and Nonsteroidal Anti-Inflammatory Drugs on Cytochrome P450 Metabolites of Arachidonic Acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Celecoxib; Cytochrome P-450 Enzyme System; Heart; Hydroxyeicosatetraenoic Acids; Inflammation; Kidney; Lactones; Male; Meloxicam; Rats; Rats, Sprague-Dawley; Sulfones; Thiazines; Thiazoles | 2018 |
COX Inhibition Profiles and Molecular Docking Studies of the Lignan Hinokinin and Some Synthetic Derivatives.
Topics: 4-Butyrolactone; Benzodioxoles; Binding Sites; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Lactones; Lignans; Meloxicam; Molecular Docking Simulation; Protein Binding; Quantitative Structure-Activity Relationship; Substrate Specificity; Sulfones | 2018 |