Page last updated: 2024-08-16

rofecoxib and elastin

rofecoxib has been researched along with elastin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirota, T; Ikeda, T; Inoue, S; Kawai, K; Koyama, K; Oitate, M1
Hirota, T; Hosokawa, T; Ikeda, T; Miura, S; Murai, T; Oitate, M; Oonishi, T; Senoo, A; Takahashi, M1
Hirota, T; Ikeda, T; Miura, S; Murai, T; Oitate, M1
Hirota, T; Miyajima, A; Muto, T; Okamoto, M1

Other Studies

4 other study(ies) available for rofecoxib and elastin

ArticleYear
Covalent binding of radioactivity from [14C]rofecoxib, but not [14C]celecoxib or [14C]CS-706, to the arterial elastin of rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:8

    Topics: Animals; Aorta, Thoracic; Carbon Radioisotopes; Celecoxib; Cyclooxygenase 2 Inhibitors; Elastin; Lactones; Male; Protein Binding; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones; Tissue Distribution

2006
Mechanism for covalent binding of rofecoxib to elastin of rat aorta.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Chromatography, High Pressure Liquid; Elastin; In Vitro Techniques; Lactones; Male; Microscopy, Electron, Transmission; Molecular Structure; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sulfones; Tandem Mass Spectrometry

2007
Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:10

    Topics: 2-Aminoadipic Acid; Aged; Aldehydes; Animals; Aorta, Abdominal; Aorta, Thoracic; Cell Line; Cyclooxygenase 2 Inhibitors; Elastin; Female; Humans; Lactones; Male; Rats; Rats, Sprague-Dawley; Sulfones

2007
Disruption of elastic lamellae in aorta and dysfunction of vaso-regulation by rofecoxib in rats.
    The Journal of toxicological sciences, 2013, Volume: 38, Issue:5

    Topics: Administration, Oral; Age Factors; Amino Acids; Animals; Aorta; Arterial Pressure; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Desmosine; Elastic Tissue; Elasticity; Elastin; Humans; Injections, Subcutaneous; Isodesmosine; Lactones; Male; Rats; Rats, Sprague-Dawley; Sulfones

2013
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