robustaflavone and amentoflavone

robustaflavone has been researched along with amentoflavone* in 5 studies

Other Studies

5 other study(ies) available for robustaflavone and amentoflavone

ArticleYear
Two new phenolic glycosides from the leaves of Garcinia epunctata Stapf.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2020, Jan-28, Volume: 75, Issue:1-2

    The leaves of Garcinia epunctata Stapf have furnished two new phenolic glucosides, epunctosides A and B, along with 13 known secondary metabolites identified as lanceoloside A, betulinic acid, lupeol, stigmasterol, β-sitosterol, β-sitosterol-3-O-β-d-glucopyranoside, stigmasterol-3-O-β-d-glucopyranoside, luteolin-7-O-glucoside, quercitin-7-O-glucoside, amentoflavone, robustaflavone, 4'-O-methyl-amentoflavone and 4'-O-methyl-robustaflavone. All structures were established from chemical and spectroscopic evidence including 1D and 2D NMR data as well as by comparing the obtained spectroscopic data with literature. This is the first report of the presence of phenolic glucosides in the genus Garcinia.

    Topics: Betulinic Acid; Biflavonoids; Garcinia; Glycosides; Pentacyclic Triterpenes; Phenols; Plant Leaves; Secondary Metabolism; Sitosterols; Stigmasterol; Triterpenes

2020
Probing the Antiallergic and Anti-inflammatory Activity of Biflavonoids and Dihydroflavonols from Dietes bicolor.
    Journal of natural products, 2018, 02-23, Volume: 81, Issue:2

    Dietes bicolor (Iridaceae) is an ornamental plant used by African local healers to treat diarrhea and dysentery. A new dihydroflavonol, (2R,3R)-3,5,7-trihydroxy-8-methoxyflavanone (1); two known dihydroflavonols, trans-3-hydroxy-5-methoxy-6,7-methylenedioxyflavanone (2) and trans-3-hydroxy-5,7-dimethoxyflavanone (3); the known isoflavone orobol 7,3'-di-O-methyl ether (4); the known biflavones lanaroflavone (5), robustaflavone (6), and amentoflavone (7); and β-sitosterol (8) were isolated from the CH

    Topics: Anti-Allergic Agents; Anti-Inflammatory Agents; Biflavonoids; Cell Line, Tumor; Humans; Iridaceae; Mast Cells; Plant Extracts; Plant Leaves; Sitosterols

2018
In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania) amazonensis.
    Memorias do Instituto Oswaldo Cruz, 2014, Volume: 109, Issue:8

    This study is the first phytochemical investigation of Selaginella sellowii and demonstrates the antileishmanial activity of the hydroethanolic extract from this plant (SSHE), as well as of the biflavonoids amentoflavone and robustaflavone, isolated from this species. The effects of these substances were evaluated on intracellular amastigotes of Leishmania (Leishmania) amazonensis, an aetiological agent of American cutaneous leishmaniasis. SSHE was highly active against intracellular amastigotes [the half maximum inhibitory concentration (IC50) = 20.2 µg/mL]. Fractionation of the extract led to the isolation of the two bioflavonoids with the highest activity: amentoflavone, which was about 200 times more active (IC50 = 0.1 μg/mL) and less cytotoxic than SSHE (IC50 = 2.2 and 3 μg/mL, respectively on NIH/3T3 and J774.A1 cells), with a high selectivity index (SI) (22 and 30), robustaflavone, which was also active against L. amazonensis (IC50 = 2.8 µg/mL), but more cytotoxic, with IC50 = 25.5 µg/mL (SI = 9.1) on NIH/3T3 cells and IC50 = 3.1 µg/mL (SI = 1.1) on J774.A1 cells. The production of nitric oxide (NO) was lower in cells treated with amentoflavone (suggesting that NO does not contribute to the leishmanicidal mechanism in this case), while NO release was higher after treatment with robustaflavone. S. sellowii may be a potential source of biflavonoids that could provide promising compounds for the treatment of cutaneous leishmaniasis.

    Topics: Animals; Antiprotozoal Agents; Biflavonoids; Female; Leishmania; Leishmaniasis, Cutaneous; Macrophages; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; NIH 3T3 Cells; Nitric Oxide; Phytotherapy; Plant Extracts; Primary Cell Culture; Selaginellaceae

2014
Bioactive compounds of inhibiting xanthine oxidase from Selaginella labordei.
    Natural product research, 2009, Volume: 23, Issue:4

    Four flavone compounds were isolated from the effective fractions inhibiting xanthine oxidase (XOD) of the medicinal plant Selaginella labordei with anti-virus activity, and the structures were elucidated as 4'-methylether robustaflavone (1), robustaflavone (2), eriodictyol (3) and amentoflavone (4). The 50% inhibitory concentration (IC(50)) of the three compounds of inhibiting XOD were 61.0, 0.199, 16.0 and 32.0 mg L(-1), respectively. All of these compounds were isolated from the species for the first time, and eriodictyol was found from Selaginellaceae for the first time. Among these compounds, robustaflavone has been reported as an effective compound against the hepatitis B virus.

    Topics: Biflavonoids; Enzyme Activation; Flavanones; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts; Selaginellaceae; Xanthine Oxidase

2009
[Study on HPLC fingerprint characteristics of Selaginella plants].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:20

    To establish a method to analyze HPLC fingerprint characteristics of 10 plants from Selaginella.. HPLC was applied for establishment of fingerprints, which were used to evaluate and distinguish the different species of Selaginella.. The different species from Selaginella showed different HPLC fingerprint characteristic. The samples of the same species but collected in different period, different environment or different locations showed certain difference in fingerprints. 2 important mutual fingerprint peaks were found in the 10 plants of Selaginella species and 5 peaks can be used as "main fingerprint peaks". The dates of these peaks can used for assessment of phylogenetic relation among species and evaluation of quality.

    Topics: Biflavonoids; China; Chromatography, High Pressure Liquid; Plants, Medicinal; Selaginellaceae; Species Specificity

2007