Compounds > ro 5-4864

ro 5-4864 and picrotoxin

ro 5-4864 has been researched along with picrotoxin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnard, EA; Darlison, MG; Harvey, RJ; Zaman, SH1
Drummer, HL; Woolley, DE1
Dai, KS; Drummer, HL; Hasan, ZA; Woolley, DE1
Dai, KS; Woolley, DE1
Gee, KW; Lawrence, LJ; Yamamura, HI1
Simmonds, MA1
Arbilla, S; Langer, SZ; Lista, A1
File, SE; Pellow, S2
File, SE1
File, SE; Green, AR; Nutt, DJ; Vincent, ND1
Ramanjaneyulu, R; Ticku, MK1

Reviews

2 review(s) available for ro 5-4864 and picrotoxin

ArticleYear
Interactions of pyrethroid insecticides with chloride ionophore-associated binding sites.
    Neurotoxicology, 1985,Summer, Volume: 6, Issue:2

    Topics: Animals; Benzodiazepinones; Brain; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Drug Interactions; Guinea Pigs; Ion Channels; Picrotoxin; Pyrethrins; Radioligand Assay; Rats; Receptors, GABA-A; Sesterterpenes

1985
Behavioural actions of Ro 5-4864: a peripheral-type benzodiazepine?
    Life sciences, 1984, Jul-16, Volume: 35, Issue:3

    Topics: Animals; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain; Convulsants; Drug Interactions; Flumazenil; Humans; Isoquinolines; Kidney; Phenytoin; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A

1984

Other Studies

10 other study(ies) available for ro 5-4864 and picrotoxin

ArticleYear
Unusual effects of benzodiazepines and cyclodiene insecticides on an expressed invertebrate GABAA receptor.
    FEBS letters, 1992, Aug-03, Volume: 307, Issue:3

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Diazepam; Endrin; Heptachlor Epoxide; Insecticides; Lymnaea; Picrotoxin; Receptors, GABA-A; RNA; Transcription, Genetic

1992
Toxicokinetics of Ro 5-4864, lindane and picrotoxin compared.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2

    Topics: Animals; Behavior, Animal; Benzodiazepinones; Body Temperature; Body Weight; Convulsants; Dose-Response Relationship, Drug; Eating; Female; Hexachlorocyclohexane; Picrotoxin; Rats; Rats, Inbred Strains; Seizures

1991
Changes in limbic evoked potentials produced by the atypical benzodiazepine Ro 5-4864.
    Proceedings of the Western Pharmacology Society, 1991, Volume: 34

    Topics: Animals; Benzodiazepinones; Convulsants; Evoked Potentials; Female; Hexachlorocyclohexane; Hippocampus; Limbic System; Picrotoxin; Rats; Rats, Inbred Strains; Seizures

1991
Ro 5-4864, like picrotoxin, enhances EPSP-spike coupling in the freely behaving rat.
    Brain research bulletin, 1991, Volume: 27, Issue:1

    Topics: Animals; Benzodiazepinones; Convulsants; Electric Stimulation; Evoked Potentials; Female; Hippocampus; Picrotoxin; Rats; Rats, Inbred Strains; Seizures

1991
Antagonism of flurazepam and other effects of Ro15-1788, PK8165 and Ro5-4864 on the GABA-A receptor complex in rat cuneate nucleus.
    European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1

    Topics: Animals; Anticonvulsants; Benzodiazepinones; Drug Synergism; Flumazenil; Flurazepam; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Pentobarbital; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A

1985
The facilitation by diazepam of the electrically evoked release of [3H]5-HT from rat cortical slices is antagonized by picrotoxin and Ro 5-4864.
    European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2

    Topics: Animals; Benzodiazepinones; Cerebral Cortex; Diazepam; Electric Stimulation; In Vitro Techniques; Picrotoxin; Rats; Serotonin

1988
Pro- and anti-convulsant properties of PK 11195, a ligand for benzodiazepine binding sites: development of tolerance.
    British journal of pharmacology, 1984, Volume: 83, Issue:2

    Topics: Animals; Anticonvulsants; Benzodiazepinones; Convulsants; Diazepam; Drug Interactions; Drug Tolerance; Isoquinolines; Ligands; Male; Mice; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Strychnine

1984
RO5-4864, a ligand for benzodiazepine micromolar and peripheral binding sites: antagonism and enhancement of behavioural effects.
    Psychopharmacology, 1983, Volume: 80, Issue:2

    Topics: Animals; Behavior, Animal; Benzodiazepinones; Drug Interactions; Flumazenil; Male; Motor Activity; Phenytoin; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A

1983
On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain.
    Psychopharmacology, 1984, Volume: 82, Issue:3

    Topics: Animals; Benzodiazepinones; Binding Sites; Brain; Convulsants; Diazepam; Electroshock; Flumazenil; Male; Mice; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures

1984
RO5-4864 inhibits the binding of [35S]t-butylbicyclophosphorothionate to rat brain membranes.
    Life sciences, 1984, Feb-13, Volume: 34, Issue:7

    Topics: Androstanes; Animals; Azasteroids; Benzodiazepinones; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Male; Picrotoxin; Radioligand Assay; Rats

1984