ro 5-4864 and n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide

ro 5-4864 has been researched along with n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (23.08)18.2507
2000's7 (53.85)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW; TenBrink, RE1
Goodman, MM; Miller, AH; Voll, RJ; Wang, E; Yu, W1
Ittner, LM; Kassiou, M; Scarf, AM1
Cavallaro, S; Costa, E; Guidotti, A; Korneyev, A; Kozikowski, AP; Ma, D; Polo, A; Romeo, E1
Boujrad, N; Kotoula, M; Kozikowski, AP; Ma, D; Papadopoulos, V; Tückmantel, W1
Chopde, CT; Jain, SP; Khisti, RT1
Biggio, G; Latrofa, A; Papi, G; Pisu, MG; Porcu, P; Serra, M; Trapani, G1
Carayon, P; Gavish, M; Höpfner, M; Jansen, A; Kozikowski, AP; Maaser, K; Riecken, EO; Scherübl, H; Weisinger, G; Weizman, A; Zeitz, M1
Belachew, S; Hans, G; Lallemend, F; Malgrange, B; Moonen, G; Nguyen, L; Rigo, JM; Robe, P; Rogister, B; Wislet-Gendebien, S1
Campàs, C; Coll-Mulet, L; Cosialls, AM; de Frias, M; Domingo, A; Gil, J; González-Gironès, DM; Iglesias-Serret, D; Pons, G; Santidrián, AF1
Burnett, AL; Chen, H; Chung, JY; Midzak, A; Papadopoulos, V; Zirkin, BR1
Bode, J; Caballero, B; Gavish, M; Leschiner, S; Veenman, L1
Li, X; Wu, C; Yang, B; Yu, S; Zhang, Y1

Reviews

1 review(s) available for ro 5-4864 and n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide

ArticleYear
The translocator protein (18 kDa): central nervous system disease and drug design.
    Journal of medicinal chemistry, 2009, Feb-12, Volume: 52, Issue:3

    Topics: Acetamides; Apoptosis; Central Nervous System; Central Nervous System Diseases; Drug Design; Humans; Indoleacetic Acids; Indoles; Mitochondrial Membranes; Neurodegenerative Diseases; Phenyl Ethers; Pyrazoles; Pyrimidines; Receptors, GABA

2009

Other Studies

12 other study(ies) available for ro 5-4864 and n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide

ArticleYear
(S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Animals; Antipsychotic Agents; Biological Availability; CHO Cells; Cricetinae; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ergolines; Humans; Molecular Structure; Piperazines; Protein Binding; Quinpirole; Receptors, Adrenergic; Receptors, Dopamine D4; Receptors, Serotonin; Schizophrenia; Sulfonamides

1996
Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Binding, Competitive; Fluorine Radioisotopes; Isoquinolines; Kidney; Ligands; Mitochondrial Membranes; Positron-Emission Tomography; Radioligand Assay; Radiopharmaceuticals; Rats; Receptors, GABA-A

2008
Stimulation of brain steroidogenesis by 2-aryl-indole-3-acetamide derivatives acting at the mitochondrial diazepam-binding inhibitor receptor complex.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Behavior, Animal; Benzodiazepinones; Binding, Competitive; Brain; Carrier Proteins; Corticosterone; Diazepam Binding Inhibitor; In Vitro Techniques; Indoleacetic Acids; Isoquinolines; Male; Mitochondria; Orchiectomy; Pregnenolone; Rats; Rats, Sprague-Dawley; Solubility; Steroids; Tricarboxylic Acids

1993
Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor.
    Journal of medicinal chemistry, 1997, Aug-01, Volume: 40, Issue:16

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Benzodiazepinones; Biological Transport; Cholesterol; Clonazepam; Fluorescent Dyes; Hypolipidemic Agents; Indoleacetic Acids; Isoquinolines; Ligands; Male; Mice; Microscopy, Fluorescence; Mitochondria; Rats; Receptors, GABA-A; Tumor Cells, Cultured

1997
Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:1

    Topics: Animals; Antidepressive Agents; Benzodiazepinones; Bicuculline; Fluoxetine; Indoleacetic Acids; Male; Mice; Pregnanolone; Receptors, GABA-A; Swimming; Time Factors

2000
Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes.
    European journal of pharmacology, 2001, Dec-07, Volume: 432, Issue:2-3

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Flumazenil; Imidazoles; Indoleacetic Acids; Isoquinolines; Ligands; Membrane Proteins; Membranes; Nordazepam; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tritium

2001
Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells.
    British journal of cancer, 2001, Nov-30, Volume: 85, Issue:11

    Topics: Adult; Aged; Apoptosis; Benzodiazepinones; Cell Cycle; Colorectal Neoplasms; Dose-Response Relationship, Drug; G1 Phase; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Indoleacetic Acids; Intracellular Membranes; Isoquinolines; Ligands; Membrane Potentials; Middle Aged; Mitochondria; Receptors, GABA-A; Resting Phase, Cell Cycle; RNA, Messenger; Tumor Cells, Cultured

2001
Peripheral benzodiazepine receptor (PBR) ligand cytotoxicity unrelated to PBR expression.
    Biochemical pharmacology, 2005, Mar-01, Volume: 69, Issue:5

    Topics: Apoptosis; Benzodiazepinones; Cell Survival; Humans; Indoleacetic Acids; Jurkat Cells; Ligands; Membrane Potentials; Mitochondria; Necrosis; Neuroblastoma; Oligopeptides; Receptors, GABA-A

2005
The potential anticancer agent PK11195 induces apoptosis irrespective of p53 and ATM status in chronic lymphocytic leukemia cells.
    Haematologica, 2007, Volume: 92, Issue:12

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; B-Lymphocytes; Benzodiazepinones; Caspase Inhibitors; Caspases; Cell Cycle Proteins; Cytochromes c; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Enzyme Activation; Female; Humans; Hypolipidemic Agents; Indoleacetic Acids; Isoquinolines; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Protein Serine-Threonine Kinases; Receptors, GABA; T-Lymphocytes; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Voltage-Dependent Anion Channels

2007
Drug ligand-induced activation of translocator protein (TSPO) stimulates steroid production by aged brown Norway rat Leydig cells.
    Endocrinology, 2013, Volume: 154, Issue:6

    Topics: Age Factors; Androstenols; Animals; Benzodiazepinones; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Indoleacetic Acids; Leydig Cells; Male; Mice; Rats; Rats, Inbred BN; Receptors, GABA; Steroids; Testis

2013
Concentration-dependent bimodal effect of specific 18 kDa translocator protein (TSPO) ligands on cell death processes induced by ammonium chloride: potential implications for neuropathological effects due to hyperammonemia.
    CNS & neurological disorders drug targets, 2014, Volume: 13, Issue:4

    Topics: Ammonium Chloride; Benzodiazepinones; Cardiolipins; Cell Death; Cell Line, Tumor; Cell Shape; Dose-Response Relationship, Drug; GABA Agents; Glutamine; Humans; Hyperammonemia; Indoleacetic Acids; Isoquinolines; L-Lactate Dehydrogenase; Ligands; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mitochondria; Neuroprotective Agents; Propidium; Receptors, GABA

2014
The ligands of translocator protein inhibit human Th1 responses and the rejection of murine skin allografts.
    Clinical science (London, England : 1979), 2017, 02-01, Volume: 131, Issue:4

    Topics: Adolescent; Adult; Animals; Benzodiazepinones; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Drug Evaluation, Preclinical; Female; Graft Rejection; Humans; Indoleacetic Acids; Ligands; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphorylation; Receptors, GABA; Signal Transduction; Skin Transplantation; STAT Transcription Factors; T-Box Domain Proteins; Th1 Cells; Young Adult

2017