Page last updated: 2024-08-24

ro 5-3335 and pyrroles

ro 5-3335 has been researched along with pyrroles in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (93.75)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Clercq, E; Desmyter, J; Pauwels, R; Reymen, D; Schols, D; Vandamme, AM; Witvrouw, M; Yamamoto, N1
Holly, M; Hsu, MC; Potash, MJ; Richman, DD; Schutt, AD; Sherman, MI; Slice, LW; Volsky, DJ2
Hsu, MC; Shahabuddin, M; Volsky, B; Volsky, DJ1
Bentsman, G; McKinley, G; Potash, MJ; Volsky, DJ1
Balzarini, J; De Clercq, E; Debyser, Z; Desmyter, J; Thormar, H; Witvrouw, M1
Desai-Yajnik, V; Gechlik, G; Hadzic, E; Malhotra, S; Modlinger, P; Samuels, HH1
Cupelli, LA; Hsu, MC1
Pitha, PM; Popik, W1
Crowe, SM; Dunne, AL; Mills, J; Siregar, H1
Braddock, M; Cannon, P; Kingsman, AJ; Kingsman, SM; Muckenthaler, M1
Kisanuki, S; Kiso, Y1
Baba, M; Gohnai, K; Hashimoto, K; Sato, M; Shigeta, S1
Baba, M; Hashimoto, K; Kira, T; Okamoto, T; Shigeta, S1
Czarnik, AW; Galan, AA; Halim, NS; Heldsinger, A; Loo, JA; Mack, DP; Mei, HY; Moreland, DW; Sannes-Lowery, KA; Sharmeen, L; Truong, HN1
Feng, DY; Li, WY; Luo, MC; Wang, HY; Xiao, J; Xu, CD; Zhou, SY; Zhou, T1

Other Studies

16 other study(ies) available for ro 5-3335 and pyrroles

ArticleYear
Cell type-specific anti-human immunodeficiency virus type 1 activity of the transactivation inhibitor Ro5-3335.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:12

    Topics: Antiviral Agents; Benzodiazepinones; Cytopathogenic Effect, Viral; DNA; HIV-1; Humans; Pyrroles; RNA; Transcriptional Activation

1992
Discovery and characterization of an HIV-1 Tat antagonist.
    Biochemical Society transactions, 1992, Volume: 20, Issue:2

    Topics: Animals; Antiviral Agents; Benzodiazepinones; CHO Cells; Cricetinae; Gene Deletion; Gene Expression; Gene Products, tat; Genes, tat; HIV Long Terminal Repeat; HIV-1; HIV-2; Kinetics; Promoter Regions, Genetic; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Virus Replication; Zidovudine

1992
Restoration of cell surface CD4 expression in human immunodeficiency virus type 1-infected cells by treatment with a Tat antagonist.
    Journal of virology, 1992, Volume: 66, Issue:11

    Topics: Antiviral Agents; Benzodiazepinones; CD4 Antigens; Cells, Cultured; Dose-Response Relationship, Drug; Gene Products, env; Gene Products, tat; HIV Envelope Protein gp160; HIV-1; Humans; Protein Precursors; Pyrroles; RNA, Messenger; T-Lymphocytes; tat Gene Products, Human Immunodeficiency Virus; Virus Replication

1992
A Tat antagonist inhibits HIV-1 induction in naturally infected and experimentally infected T cells.
    Biochemical and biophysical research communications, 1992, Nov-30, Volume: 189, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Benzodiazepinones; Cell Line; Cloning, Molecular; DNA, Viral; Gene Products, tat; HIV Core Protein p24; HIV-1; Pyrroles; Rats; T-Lymphocytes; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate

1992
Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist.
    Science (New York, N.Y.), 1991, Dec-20, Volume: 254, Issue:5039

    Topics: Antiviral Agents; Benzodiazepinones; Cell Line; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; HIV-2; Humans; Kinetics; Promoter Regions, Genetic; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Virus Replication; Zidovudine

1991
Inhibition of visna virus replication and cytopathic effect in sheep choroid plexus cell cultures by selected anti-HIV agents.
    Antiviral research, 1995, Volume: 27, Issue:1-2

    Topics: Animals; Antiviral Agents; Benzodiazepinones; Cattle; Cells, Cultured; Choroid Plexus; Cytopathogenic Effect, Viral; HIV-1; Lectins; Pyrroles; Reverse Transcriptase Inhibitors; Sheep; Virus Replication; Visna-maedi virus

1995
Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator.
    Journal of virology, 1995, Volume: 69, Issue:8

    Topics: Antiviral Agents; Base Sequence; Benzodiazepinones; Chloramphenicol O-Acetyltransferase; Gene Products, tat; HeLa Cells; HIV Long Terminal Repeat; HIV-1; Humans; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Pyrroles; Receptors, Thyroid Hormone; tat Gene Products, Human Immunodeficiency Virus

1995
The human immunodeficiency virus type 1 Tat antagonist, Ro 5-3335, predominantly inhibits transcription initiation from the viral promoter.
    Journal of virology, 1995, Volume: 69, Issue:4

    Topics: Antiviral Agents; Benzodiazepinones; Chloramphenicol O-Acetyltransferase; Gene Products, tat; HeLa Cells; HIV Long Terminal Repeat; HIV-1; Humans; Promoter Regions, Genetic; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic

1995
Differential effect of tumor necrosis factor-alpha and herpes simplex virus type 1 on the Tat-targeted inhibition of human immunodeficiency virus type 1 replication.
    Virology, 1994, Aug-01, Volume: 202, Issue:2

    Topics: Antiviral Agents; Benzodiazepinones; Gene Expression Regulation, Viral; Gene Products, tat; Genes, tat; Herpesvirus 1, Human; HIV-1; Humans; In Vitro Techniques; Lymphocytes; Pyrroles; Retroviridae Proteins; RNA, Viral; tat Gene Products, Human Immunodeficiency Virus; Tumor Necrosis Factor-alpha; Virus Replication

1994
HIV replication in chronically infected macrophages is not inhibited by the Tat inhibitors Ro-5-3335 and Ro-24-7429.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:3

    Topics: Antigens, Viral; Antiviral Agents; Benzodiazepines; Benzodiazepinones; Cells, Cultured; HIV-1; Humans; Macrophages; Pyrroles; Virus Replication

1994
Inhibition of human immunodeficiency virus type 1 Tat-dependent activation of translation in Xenopus oocytes by the benzodiazepine Ro24-7429 requires trans-activation response element loop sequences.
    Journal of virology, 1994, Volume: 68, Issue:1

    Topics: Animals; Antiviral Agents; Base Sequence; Benzodiazepines; Benzodiazepinones; Gene Expression Regulation, Viral; Gene Products, tat; HIV-1; Humans; Models, Genetic; Molecular Sequence Data; Nucleic Acid Conformation; Oocytes; Protein Biosynthesis; Pyrroles; Regulatory Sequences, Nucleic Acid; RNA, Viral; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation; Tumor Cells, Cultured; Virus Replication; Xenopus

1994
[Anti-HIV compounds].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Benzodiazepinones; Gene Products, tat; HIV; HIV Protease Inhibitors; Humans; Nitroso Compounds; Pyrroles; tat Gene Products, Human Immunodeficiency Virus

1993
Heat shock induces HIV-1 replication in chronically infected promyelocyte cell line OM10.1.
    Archives of virology, 1996, Volume: 141, Issue:3-4

    Topics: Alkaloids; Antibodies; Antiviral Agents; Benzodiazepinones; Cell Line; Enzyme Inhibitors; Gene Products, tat; Granulocytes; Heat-Shock Response; HIV-1; Humans; NF-kappa B; Pentoxifylline; Protein Kinase C; Pyrroles; Staurosporine; tat Gene Products, Human Immunodeficiency Virus; Tumor Necrosis Factor-alpha; Virus Activation

1996
2-Glycineamide-5-chlorophenyl 2-pyrryl ketone, a non-benzodiazepin Tat antagonist, is effective against acute and chronic HIV-1 infections in vitro.
    Antiviral research, 1996, Volume: 32, Issue:2

    Topics: Anti-HIV Agents; Benzodiazepines; Benzodiazepinones; Cell Line; Gene Products, tat; HIV-1; Humans; Molecular Structure; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Virus Replication

1996
Discovery of selective, small-molecule inhibitors of RNA complexes--I. The Tat protein/TAR RNA complexes required for HIV-1 transcription.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:6

    Topics: Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Base Sequence; Benzodiazepinones; Camptothecin; Gene Products, tat; HeLa Cells; HIV-1; Humans; Molecular Sequence Data; Pyrroles; RNA, Viral; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Transcriptional Activation; Virus Replication

1997
Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock.
    The Journal of biological chemistry, 2016, Oct-14, Volume: 291, Issue:42

    Topics: Animals; Benzodiazepinones; Core Binding Factor Alpha 2 Subunit; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Mice; NF-kappa B p50 Subunit; Protein Binding; Pyrroles; RAW 264.7 Cells; Shock, Septic; Signal Transduction; Toll-Like Receptor 4

2016