ro 48-8071 has been researched along with fluorouracil in 1 studies
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balliano, G; Bussolino, F; Di Nicolantonio, F; Giraudo, E; Maione, F; Meda, C; Oliaro-Bosso, S; Viola, F | 1 |
1 other study(ies) available for ro 48-8071 and fluorouracil
| Article | Year |
|---|---|
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination.
Topics: Animals; Apoptosis; Benzophenones; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholesterol; Colonic Neoplasms; Disease Models, Animal; Fluorouracil; HCT116 Cells; Humans; Intramolecular Transferases; Male; Mice; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |