ro 46-2005 has been researched along with bq 123 in 9 studies
| Studies (ro 46-2005) | Trials (ro 46-2005) | Recent Studies (post-2010) (ro 46-2005) | Studies (bq 123) | Trials (bq 123) | Recent Studies (post-2010) (bq 123) |
|---|---|---|---|---|---|
| 26 | 0 | 1 | 1,391 | 63 | 152 |
| Protein | Taxonomy | ro 46-2005 (IC50) | bq 123 (IC50) |
|---|---|---|---|
| Endothelin-1 receptor | Homo sapiens (human) | 0.017 | |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | 0.014 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azuma, H; Hamasaki, H; Isotani, E; Matsubara, O; Obayashi, S; Sato, J | 1 |
| Kizawa, Y; Murakami, H; Nakajima, Y; Nakano, J; Sano, M; Uno, H | 1 |
| Chiou, WJ; Huang, ZJ; Opgenorth, TJ; Vidal, MJ; Wu-Wong, JR | 1 |
| Buchan, KW; Magnusson, H; Rabe, KF; Sumner, MJ; Watts, IS | 1 |
| Battistini, B; Corder, R; Doherty, AM; Warner, TD | 1 |
| Chiou, WJ; Dixon, DB; Opgenorth, TJ; Wu-Wong, JR | 1 |
| Aso, T; Azuma, H; Hamasaki, H; Obayashi, S; Sakamoto, S; Sato, J | 1 |
| Goto, K | 1 |
| Kataoka, K; Kurihara, H; Kurihara, Y | 1 |
3 review(s) available for ro 46-2005 and bq 123
| Article | Year |
|---|---|
Endothelin receptor antagonists: actions and rationale for their development.
Topics: Animals; Antibodies, Monoclonal; Aspartic Acid Endopeptidases; Disease Models, Animal; Drug Design; Endothelin Receptor Antagonists; Endothelin-Converting Enzymes; Endothelins; Humans; Metalloendopeptidases; Oligopeptides; Peptides, Cyclic; Pyrimidines; Receptors, Endothelin; Sulfonamides | 1994 |
[Discovery of endothelin and its significance].
Topics: Amino Acid Sequence; Animals; Azepines; Cardiovascular Diseases; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Humans; Indans; Indoles; Molecular Sequence Data; Peptides, Cyclic; Pyrimidines; Receptors, Endothelin; Sulfonamides; Vasoconstriction | 2004 |
[Endothelin and essential hypertension].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Humans; Hypertension; Mice; Mice, Knockout; Muscle Contraction; Muscle, Smooth, Vascular; Peptides, Cyclic; Pyrimidines; Receptors, Endothelin; Sulfonamides | 2004 |
6 other study(ies) available for ro 46-2005 and bq 123
| Article | Year |
|---|---|
Different localization of ETA and ETB receptors in the hyperplastic vascular wall.
Topics: Analysis of Variance; Angioplasty; Angioplasty, Balloon; Animals; Binding, Competitive; Carotid Arteries; Endothelins; Hyperplasia; Male; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Rabbits; Radioligand Assay; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides | 1995 |
Pharmacological profiles of contractile endothelin receptors in guinea pig hilar bronchus.
Topics: Animals; Binding, Competitive; Bronchi; Endothelin Receptor Antagonists; Endothelins; Guinea Pigs; In Vitro Techniques; Male; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Receptors, Endothelin; Sulfonamides; Vasoconstrictor Agents; Viper Venoms | 1994 |
Endothelin receptors in human smooth muscle cells: antagonist potency differs on agonist-evoked responses.
Topics: Binding Sites; Cells, Cultured; DNA; Endothelin Receptor Antagonists; Endothelins; Humans; Ligands; Molecular Weight; Muscle, Smooth, Vascular; Peptides, Cyclic; Pericardium; Pyrimidines; Receptors, Endothelin; Signal Transduction; Sulfonamides | 1994 |
Characterisation of the endothelin receptor mediating contraction of human pulmonary artery using BQ123 and Ro 46-2005.
Topics: Aged; Amino Acid Sequence; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Peptides, Cyclic; Pulmonary Artery; Pyrimidines; Receptors, Endothelin; Sulfonamides; Vasoconstrictor Agents; Viper Venoms | 1994 |
Dissociation characteristics of endothelin ETA receptor agonists and antagonists.
Topics: Amino Acid Sequence; Animals; Azepines; Endothelin Receptor Antagonists; Endothelins; Indoles; Molecular Sequence Data; Peptides, Cyclic; Pituitary Neoplasms; Pyrimidines; Rats; Receptor, Endothelin A; Receptors, Endothelin; Sulfonamides; Tumor Cells, Cultured | 1995 |
The mechanism of myometrial contractions induced by endothelin-1 in rat.
Topics: Animals; Endothelin Receptor Antagonists; Endothelin-1; Female; Peptides, Cyclic; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides; Uterine Contraction | 1997 |