ro 46-2005 has been researched along with bosentan anhydrous in 2 studies
| Studies (ro 46-2005) | Trials (ro 46-2005) | Recent Studies (post-2010) (ro 46-2005) | Studies (bosentan anhydrous) | Trials (bosentan anhydrous) | Recent Studies (post-2010) (bosentan anhydrous) |
|---|---|---|---|---|---|
| 26 | 0 | 1 | 1,836 | 215 | 630 |
| Protein | Taxonomy | ro 46-2005 (IC50) | bosentan anhydrous (IC50) |
|---|---|---|---|
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | 0.095 | |
| Endothelin receptor type B | Homo sapiens (human) | 0.3044 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.2317 | |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | 0.0047 | |
| Endothelin-1 receptor | Sus scrofa (pig) | 0.0075 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolli, MH; Boss, C; Gatfield, J | 1 |
| Bruneval, P; Clozel, JP; Clozel, M; Heudes, D; Osterwalder, R; Qiu, C; Roeckel, A | 1 |
1 review(s) available for ro 46-2005 and bosentan anhydrous
| Article | Year |
|---|---|
From bosentan (Tracleer®) to macitentan (Opsumit®): The medicinal chemistry perspective.
Topics: Bosentan; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Humans; Molecular Structure; Pyrimidines; Receptors, Endothelin; Structure-Activity Relationship; Sulfonamides | 2016 |
1 other study(ies) available for ro 46-2005 and bosentan anhydrous
| Article | Year |
|---|---|
Effects of nonpeptide endothelin receptor antagonists in rats with reduced renal mass.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bosentan; Cilazapril; Endothelin Receptor Antagonists; Kidney; Kidney Function Tests; Male; Organ Size; Proteinuria; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides | 1999 |