Compounds > ro 32-0432
Page last updated: 2024-09-03

ro 32-0432 and ro 31-8220

ro 32-0432 has been researched along with ro 31-8220 in 4 studies

Compound Research Comparison

Studies
(ro 32-0432)		Trials
(ro 32-0432)		Recent Studies (post-2010)
(ro 32-0432)		Studies
(ro 31-8220)		Trials
(ro 31-8220)		Recent Studies (post-2010) (ro 31-8220)
56013587164

Protein Interaction Comparison

ProteinTaxonomyro 32-0432 (IC50)ro 31-8220 (IC50)
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)0.008
Serine/threonine-protein kinase 10Homo sapiens (human)0.099
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.9
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.01
Protein kinase C alpha typeHomo sapiens (human)0.033
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.0068
Ribosomal protein S6 kinase beta-1Homo sapiens (human)0.015
Mitogen-activated protein kinase kinase kinase 8Homo sapiens (human)9.95
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0116
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)0.01
Protein kinase C beta typeRattus norvegicus (Norway rat)0.01
Homeodomain-interacting protein kinase 1Homo sapiens (human)0.621
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)0.875
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)0.0529
NAD-dependent protein deacetylase sirtuin-1Homo sapiens (human)3.9
Serine/threonine-protein kinase VRK1Homo sapiens (human)0.743
NAD-dependent protein deacetylase sirtuin-3, mitochondrialHomo sapiens (human)3.7
Serine/threonine-protein kinase TBK1Homo sapiens (human)0.656

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goekjian, PG; Jirousek, MR1
Carr, AN; Dorn, GW; Hahn, H; Hambleton, M; Hewett, TE; Kimball, TF; Klevitsky, R; Koch, WJ; Kuhn, MC; Molkentin, JD; Pleger, ST1
Arandarcikaite, O; Barauskaite, J; Borutaite, V; Brown, GC; Jekabsone, A; Morkuniene, R1
Correll, RN; Hajjar, RJ; Houser, SR; Ishikawa, K; Kawase, Y; Ladage, D; Molkentin, JD; Tilemann, L1

Reviews

1 review(s) available for ro 32-0432 and ro 31-8220

ArticleYear
Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.
    Current medicinal chemistry, 1999, Volume: 6, Issue:9

    Topics: Azepines; Bryostatins; Carbazoles; Enzyme Inhibitors; Humans; Hydroxybenzoates; Indoles; Lactones; Macrolides; Maleimides; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Pyrroles; Signal Transduction; Thionucleotides

1999

Other Studies

3 other study(ies) available for ro 32-0432 and ro 31-8220

ArticleYear
Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure.
    Circulation, 2006, Aug-08, Volume: 114, Issue:6

    Topics: Animals; Calcium; Cardiac Output, Low; Cardiomyopathy, Dilated; DNA; Enzyme Activation; Female; Gene Expression Regulation; Genetic Therapy; Indoles; Male; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Infarction; Myocardium; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction

2006
Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release.
    Journal of biomedical science, 2009, Aug-11, Volume: 16

    Topics: Animals; Apoptosis; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Cytochromes c; Indoles; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Donors; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Triazenes

2009
Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.
    Circulation research, 2011, Dec-09, Volume: 109, Issue:12

    Topics: Animals; Cardiac Output; Coronary Occlusion; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heart; Heart Failure; Indoles; Maleimides; Myocardial Contraction; Myocardial Infarction; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Stroke Volume; Swine

2011