Page last updated: 2024-09-03

ro 32-0432 and pyrroles

ro 32-0432 has been researched along with pyrroles in 53 studies

Compound Research Comparison

Studies (ro 32-0432)	Trials (ro 32-0432)	Recent Studies (post-2010) (ro 32-0432)	Studies (pyrroles)	Trials (pyrroles)	Recent Studies (post-2010) (pyrroles)
56	0	13	26,129	2,815	12,100

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (13.21)	18.2507
2000's	32 (60.38)	29.6817
2010's	14 (26.42)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Birchall, AM; Bishop, J; Bradshaw, D; Cline, A; Coffey, J; Elliott, LH; Gibson, VM; Greenham, A; Hallam, TJ; Harris, W	1
Gozal, D; Gozal, E; Graff, GR; Khicha, SG; Nayak, GS; Simakajornboon, N; Torres, JE	1
Nambi, P; Wu, HL	1
Breton, JJ; Chabot-Fletcher, M	1
Bandla, HP; Gozal, D; Graff, GR; Simakajornboon, N	1
Chergui, K; Lacey, MG	1
Goekjian, PG; Jirousek, MR	1
Morris, AP; Sellin, JH; Umar, S	1
Kataoka, K; Nakamura, Y; Si, Q	1
Aiyar, N; Benovic, JL; Dang, K; Disa, J; Nambi, P; Pronin, AN	1
Huang, HC; Nguyen, T; Pickett, CB	1
Cook, DA; Nessim, MA; Vollrath, B; Wickman, G	1
Cheung, GT; Frohlich, J; Lynn, EG; O, K; Siow, YL	1
Hu, J; Krieger, C; Pelech, SL; Raymond, LA; Wagey, R	1
Huang, Y; Ishizawa, M; Ishizuka, T; Kajita, K; Kawai, Y; Kimura, M; Miura, A; Morita, H; Uno, Y; Yasuda, K	1
Mizuo, K; Narita, M; Shibasaki, M; Suzuki, T	1
Dekura, E; Kojima, F; Kosugi, Y; Naraba, H; Oh-ishi, S; Ueno, A; Yoshimura, M	1
Curtis, JL; Hu, B; Polak, T; Punturieri, A; Sonstein, J; Todt, JC	1
Hatori, K; Heisel, R; Kim, SU; Nagai, A; Ryu, JK	1
Del Pilar Gomez, M; Nasi, E; Piccoli, G	1
Lan, C; Vollrath, B; Wickman, G	1
Hofmann, DK; Thieme, C	1
Francis, K; Ham, J; Lewis, BM; Lewis, MD; Rees, DA; Scanlon, MF	1
Fresco, P; Gonçalves, J; Pinto, E; Saraiva, L	1
Han, JS; Kim, DS; Kim, TW; Yoon, MS	1
Kato, H; Narita, M; Oe, K; Shibasaki, M; Suzuki, T; Yajima, Y; Yamazaki, M	1
Diniz, C; Fresco, P; Gonçalves, J	1
Borbely, A; Mezosi, E; Nagy, EV; Paragh, G; Szabo, J; Varga, E; Varga, Z	1
Fukuda, T; Ishii, K; Isobe, K; Kawakami, Y; Nanmoku, T; Takekoshi, K	1
Bowman, L; Castranova, V; Ding, M; Huang, C; Lu, Y; Vallyathan, V	1
Alkon, DL; Bennett, MC; Epstein, H; Kuzirian, A; Nelson, TJ	1
Brown, Z; Cronshaw, DG; Kouroumalis, A; Parry, R; Ward, SG; Webb, A	1
Carr, AN; Dorn, GW; Hahn, H; Hambleton, M; Hewett, TE; Kimball, TF; Klevitsky, R; Koch, WJ; Kuhn, MC; Molkentin, JD; Pleger, ST	1
Abdala-Valencia, H; Cook-Mills, JM	1
Edvinsson, L; Henriksson, M; Stenman, E; Vikman, P	1
Miller, GM; Xie, Z	1
Bibb, JA; Greene, RW; Hawasli, AH; Molkentin, JD; Sahin, B	1
Polk, DB; Rao, RK; Seth, A; Yan, F	1
Arandarcikaite, O; Barauskaite, J; Borutaite, V; Brown, GC; Jekabsone, A; Morkuniene, R	1
Azuma, M; Morimoto-Tochigi, A; Nakajima, E; Shearer, TR; Walkup, RD	1
Brunner-Weinzierl, MC; Hollenbach, E; Kandolf, R; Kavuri, S; Klar, S; Klingel, K; Leverkus, M; Neumann, M; Wilisch-Neumann, A	1
Abuduwali, N; Jäger, A; Kraus, D; Lossdörfer, S	1
Baryshnikov, A; Grigorieva, I; Lichinitser, M; Solomko, E; Stepanova, E; Vartanian, A	1
Bogatcheva, NV; Daglis, GA; Gorshkov, BA; Kim, KM; Poirier, C; Verin, AD; Zemskova, MA	1
Correll, RN; Hajjar, RJ; Houser, SR; Ishikawa, K; Kawase, Y; Ladage, D; Molkentin, JD; Tilemann, L	1
Abuduwali, N; Deschner, J; Jäger, A; Kraus, D; Lossdörfer, S	1
Ayuzawa, R; Doi, C; Kawabata, A; Matsuzuka, T; Nguyen, TA; Pickel, L; Reischman, J; Seiler, G; Tamura, M	1
Arora, S; Rehni, AK; Singh, TG	1
Aoki, Y; Mizoguchi, H; Sakurada, S; Sakurada, T; Takeda, K; Watanabe, C	1
Liu, W; Liu, XC; Liu, ZC; Tang, SB; Yu, EH; Zhu, BH	1
Alkon, DL; Liu, QY; Xu, C	1
Chen, BC; Lin, CH; Shih, CH	1
Adhikari, P; Xu, H	1

Reviews

1 review(s) available for ro 32-0432 and pyrroles

Article	Year
Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development. Current medicinal chemistry, 1999, Volume: 6, Issue:9 Topics: Azepines; Bryostatins; Carbazoles; Enzyme Inhibitors; Humans; Hydroxybenzoates; Indoles; Lactones; Macrolides; Maleimides; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Pyrroles; Signal Transduction; Thionucleotides	1999

Article

Year

Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.

Current medicinal chemistry, 1999, Volume: 6, Issue:9

Topics: Azepines; Bryostatins; Carbazoles; Enzyme Inhibitors; Humans; Hydroxybenzoates; Indoles; Lactones; Macrolides; Maleimides; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Pyrroles; Signal Transduction; Thionucleotides

1999

Other Studies

52 other study(ies) available for ro 32-0432 and pyrroles

Article	Year
Ro 32-0432, a selective and orally active inhibitor of protein kinase C prevents T-cell activation. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2 Topics: Administration, Oral; Amino Acid Sequence; Animals; Arthritis, Experimental; Female; Indoles; Lymphocyte Activation; Male; Mice; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Rats; Rats, Inbred Lew; T-Lymphocytes	1994
Cardiorespiratory responses to systemic administration of a protein kinase C inhibitor in conscious rats. Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:2 Topics: Animals; Blood Pressure; Enzyme Inhibitors; Heart Rate; Hypercapnia; Hypoxia; Indoles; Male; Neocortex; Protein Kinase C; Pulmonary Ventilation; Pyrroles; Rats; Rats, Sprague-Dawley	1998
Transforming growth factor-beta-mediated proliferation of renal tubular epithelial cells involves pertussis toxin-sensitive G protein-and protein kinase C-dependent pathways. Pharmacology, 1998, Volume: 57, Issue:1 Topics: Animals; Cell Division; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; GTP-Binding Proteins; Indoles; Pertussis Toxin; Protein Kinase C; Pyrroles; Signal Transduction; Thymidine; Transforming Growth Factor beta; Tritium; Virulence Factors, Bordetella	1998
Effect of staurosporine on transcription factor NF-kappaB in human keratinocytes. Biochemical pharmacology, 1998, Jul-01, Volume: 56, Issue:1 Topics: Base Sequence; Cells, Cultured; Enzyme Inhibitors; Genes, Reporter; Humans; Indoles; Interleukin-8; Keratinocytes; Luciferases; NF-kappa B; Protein Kinase C; Proto-Oncogene Proteins; Pyrroles; RNA, Messenger; Staurosporine; Transcription Factor RelB; Transcription Factors	1998
Protein kinase C modulates ventilatory patterning in the developing rat. American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:3 Topics: Aging; Animals; Animals, Newborn; Blotting, Western; Brain Stem; Cerebral Cortex; Enzyme Inhibitors; Indoles; Plethysmography, Whole Body; Protein Kinase C; Pulmonary Ventilation; Pyrroles; Rats; Rats, Sprague-Dawley; Tidal Volume	1999
Modulation by dopamine D1-like receptors of synaptic transmission and NMDA receptors in rat nucleus accumbens is attenuated by the protein kinase C inhibitor Ro 32-0432. Neuropharmacology, 1999, Volume: 38, Issue:2 Topics: Animals; Dopamine; Enzyme Inhibitors; Evoked Potentials; In Vitro Techniques; Indoles; Male; Membrane Potentials; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission	1999
Murine colonic mucosa hyperproliferation. II. PKC-beta activation and cPKC-mediated cellular CFTR overexpression. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:5 Topics: Animals; Cell Division; Cell Membrane; Colon; Cystic Fibrosis Transmembrane Conductance Regulator; Cytoskeleton; Cytosol; Enzyme Inhibitors; Gene Expression Regulation; Hyperplasia; Indoles; Intestinal Mucosa; Kinetics; Male; Mice; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles	2000
Differential regulation of microglial NO production by protein kinase C inhibitors. Neurochemistry international, 2001, Volume: 38, Issue:1 Topics: Animals; Carbazoles; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Indoles; Isoquinolines; Lipopolysaccharides; Microglia; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Isoforms; Protein Kinase C; Pyrroles; Rats; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate	2001
Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors. European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2 Topics: Adenylyl Cyclases; Animals; beta-Adrenergic Receptor Kinases; Binding, Competitive; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Antisense; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; G-Protein-Coupled Receptor Kinase 5; G-Protein-Coupled Receptor Kinases; Humans; Indoles; Iodine Radioisotopes; Membranes; Peptide Fragments; Protein Serine-Threonine Kinases; Pyrroles; Radioligand Assay; Receptors, Calcitonin Gene-Related Peptide; Swine	2000
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2. Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23 Topics: Animals; Antioxidants; beta-Naphthoflavone; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Hydroquinones; Indoles; Leucine Zippers; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Kinase C; Pyrroles; Rats; Response Elements; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured	2000
The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm. British journal of pharmacology, 2001, Volume: 133, Issue:1 Topics: Animals; Anti-Bacterial Agents; Bradykinin; Cells, Cultured; Cerebral Arteries; Dogs; Dose-Response Relationship, Drug; Endothelin-1; Female; Gentamicins; Indoles; Isometric Contraction; Kanamycin; Male; Muscle, Smooth, Vascular; Neomycin; Peptides, Cyclic; Polyamines; Polyelectrolytes; Protein Kinase C; Pyrroles; Streptomycin; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasospasm, Intracranial	2001
Lipoprotein-X stimulates monocyte chemoattractant protein-1 expression in mesangial cells via nuclear factor-kappa B. Kidney international, 2001, Volume: 60, Issue:2 Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Cholesterol; Diglycerides; Diltiazem; Enzyme Inhibitors; Foam Cells; Gene Expression; Genes, Recessive; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Humans; Indoles; Lecithin Cholesterol Acyltransferase Deficiency; Lipoprotein-X; Male; Molecular Sequence Data; Monocytes; NF-kappa B; Phosphatidylcholines; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Type C Phospholipases	2001
Modulation of NMDA-mediated excitotoxicity by protein kinase C. Journal of neurochemistry, 2001, Volume: 78, Issue:4 Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Fractionation; Cell Line; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Humans; Immunoblotting; Indoles; Isoenzymes; Mitogen-Activated Protein Kinases; N-Methylaspartate; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Protein Subunits; Pyrroles; Rats; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate; Transfection	2001
Differential effect of PKC isoform on insulin- and phorbol ester-stimulated glucose uptake mechanism in rat adipocytes. IUBMB life, 2001, Volume: 51, Issue:5 Topics: Adipocytes; Androstadienes; Animals; Biological Transport, Active; Deoxyglucose; Enzyme Activation; Enzyme Inhibitors; Glucose; In Vitro Techniques; Indoles; Insulin; Male; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin	2001
Up-regulation of the G(q/11alpha) protein and protein kinase C during the development of sensitization to morphine-induced hyperlocomotion. Neuroscience, 2002, Volume: 111, Issue:1 Topics: Animals; Disease Susceptibility; Drug Administration Schedule; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Hyperkinesis; Indoles; Limbic System; Male; Mesencephalon; Mice; Morphine; Narcotics; Prosencephalon; Protein Isoforms; Protein Kinase C; Pyrroles; RGS Proteins; Up-Regulation	2002
Effects of dexamethasone and protein kinase C inhibitors on the induction of bradykinin B1 mRNA and the bradykinin B1 receptor-mediated contractile response in isolated rat ileum. Biochemical pharmacology, 2002, Jun-01, Volume: 63, Issue:11 Topics: Animals; Bradykinin; Cycloheximide; Dactinomycin; Dexamethasone; Ileum; Indoles; Interleukin-1; Isotonic Solutions; Lipopolysaccharides; Male; Muscle Contraction; Polymyxin B; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B1; Receptors, Bradykinin; RNA, Messenger; Temperature; Time Factors	2002
Activation of protein kinase C beta II by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages. The Journal of biological chemistry, 2002, Sep-27, Volume: 277, Issue:39 Topics: Acetophenones; Animals; Apoptosis; Benzopyrans; Blotting, Western; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Activation; Female; Flow Cytometry; Immunoblotting; Indoles; Inhibitory Concentration 50; Isoenzymes; Liposomes; Macrophages; Mice; Mice, Inbred C57BL; Myristic Acid; Phagocytosis; Protein Isoforms; Protein Kinase C; Protein Kinase C beta; Protein Transport; Pyrroles; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors	2002
Fractalkine and fractalkine receptors in human neurons and glial cells. Journal of neuroscience research, 2002, Aug-01, Volume: 69, Issue:3 Topics: Astrocytes; Cell Culture Techniques; Chemokine CX3CL1; Chemokines, CX3C; CX3C Chemokine Receptor 1; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoblotting; Immunohistochemistry; Indoles; Membrane Proteins; Microglia; Neurons; Protein Kinase C; Pyrroles; Receptors, Cytokine; Receptors, HIV; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction	2002
Role of protein kinase C in light adaptation of molluscan microvillar photoreceptors. The Journal of physiology, 2002, Sep-01, Volume: 543, Issue:Pt 2 Topics: Adaptation, Ocular; Animals; Calcium; Enzyme Inhibitors; Indoles; Isoenzymes; Membrane Potentials; Mollusca; Photic Stimulation; Photoreceptor Cells, Invertebrate; Protein Kinase C; Protein Kinase C-alpha; Pyrroles	2002
Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm. Circulation research, 2003, Apr-18, Volume: 92, Issue:7 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Basilar Artery; Benzamides; Biological Transport; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Muscle, Smooth, Vascular; Oxyhemoglobins; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rabbits; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Vasoconstriction	2003
Control of head morphogenesis in an invertebrate asexually produced larva-like bud ( Cassiopea andromeda; Cnidaria: Scyphozoa). Development genes and evolution, 2003, Volume: 213, Issue:3 Topics: Alkaloids; Animals; Benzophenanthridines; Biological Assay; Chromatography, Gel; Indoles; Metamorphosis, Biological; Morphogenesis; Phenanthridines; Protein Kinase C; Psychosine; Pyrroles; Reproduction; Scyphozoa	2003
Adenosine-induced IL-6 expression in pituitary folliculostellate cells is mediated via A2b adenosine receptors coupled to PKC and p38 MAPK. British journal of pharmacology, 2003, Volume: 140, Issue:4 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Androstadienes; Animals; Cells, Cultured; Dexamethasone; Estrenes; Indoles; Interleukin-6; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pituitary Gland, Anterior; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptor, Adenosine A2B; Type C Phospholipases; Vascular Endothelial Growth Factors; Wortmannin	2003
Isoform-selectivity of PKC inhibitors acting at the regulatory and catalytic domain of mammalian PKC-alpha, -betaI, -delta, -eta and -zeta. Journal of enzyme inhibition and medicinal chemistry, 2003, Volume: 18, Issue:6 Topics: Acetophenones; Alkaloids; Animals; Benzophenanthridines; Benzopyrans; Catalysis; Enzyme Inhibitors; Escherichia coli; Indoles; Isoenzymes; Phenanthridines; Piperidines; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Pyrroles; Saccharomyces cerevisiae; Sphingosine; Tamoxifen; Yeasts	2003
Thyrotropin-releasing hormone increases phospholipase D activity through stimulation of protein kinase C in GH3 cells. Endocrine, 2004, Volume: 23, Issue:1 Topics: Animals; Calcium; Cell Line, Tumor; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Isoenzymes; Maleimides; Phospholipase D; Protein Kinase C; Protein Transport; Pyrroles; Pyrrolidinones; Rats; Thyrotropin-Releasing Hormone	2004
Implication of spinal protein kinase C in the suppression of morphine-induced rewarding effect under a neuropathic pain-like state in mice. Neuroscience, 2004, Volume: 125, Issue:3 Topics: Analgesics, Opioid; Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Indoles; Ligation; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Neuralgia; Protein Kinase C; Pyrroles; Reward; Sciatic Neuropathy; Spinal Cord; Up-Regulation	2004
Facilitation of noradrenaline release by activation of adenosine A(2A) receptors triggers both phospholipase C and adenylate cyclase pathways in rat tail artery. Cardiovascular research, 2004, Sep-01, Volume: 63, Issue:4 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Arteries; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Activation; Indoles; Isoquinolines; Male; Norepinephrine; Phenethylamines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptor, Adenosine A2A; Signal Transduction; Sulfonamides; Tail; Tetradecanoylphorbol Acetate; Triazoles; Tritium; Type C Phospholipases	2004
Nongenomic effect of thyroid hormone on free-radical production in human polymorphonuclear leukocytes. The Journal of endocrinology, 2005, Volume: 185, Issue:1 Topics: Adult; Aged; Case-Control Studies; Cell Culture Techniques; Chelating Agents; Diiodothyronines; Dose-Response Relationship, Drug; Egtazic Acid; Female; Free Radicals; GTP-Binding Proteins; Humans; Hyperthyroidism; Hypothyroidism; Indoles; Iodine Radioisotopes; Middle Aged; Naphthalenes; Neutrophil Activation; Neutrophils; Peroxidase; Pertussis Toxin; Protein Kinase C; Pyrroles; Reactive Oxygen Species; Stimulation, Chemical; Superoxides; Thyroid Diseases; Thyroid Hormones; Thyroxine; Triiodothyronine	2005
Stimulation of catecholamine biosynthesis via the PKC pathway by prolactin-releasing peptide in PC12 rat pheochromocytoma cells. The Journal of endocrinology, 2005, Volume: 186, Issue:1 Topics: Animals; Catecholamines; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Hypothalamic Hormones; Indoles; Isoquinolines; MAP Kinase Signaling System; Neuropeptides; Pheochromocytoma; Prolactin-Releasing Hormone; Protein Kinase C; Pyrroles; Rats; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Sulfonamides; Tyrosine 3-Monooxygenase	2005
Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway. American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2 Topics: Animals; Cell Line; Crystallization; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; MAP Kinase Signaling System; Mice; Naphthalenes; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Pyrroles; Silicon Dioxide; Transcription Factor AP-1; Transfection	2006
Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning. Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-08, Volume: 102, Issue:45 Topics: Animals; Bryostatins; GTP-Binding Proteins; Hermissenda; Immunohistochemistry; Indoles; Learning; Macrolides; Memory; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Kinase C; Pyrroles	2005
Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22. Journal of leukocyte biology, 2006, Volume: 79, Issue:6 Topics: Acetophenones; Benzopyrans; Calcium; Calcium Channels; Calcium Signaling; Catalytic Domain; Cell Line, Tumor; Chemokine CCL17; Chemokine CCL22; Chemokines, CC; Chemotaxis; Chromones; Diglycerides; Estrenes; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Leukemia-Lymphoma, Adult T-Cell; Morpholines; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphothreonine; Protein Processing, Post-Translational; Pyrroles; Pyrrolidinones; Receptors, CCR4; Receptors, Chemokine; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; T-Lymphocytes; Th2 Cells	2006
Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure. Circulation, 2006, Aug-08, Volume: 114, Issue:6 Topics: Animals; Calcium; Cardiac Output, Low; Cardiomyopathy, Dilated; DNA; Enzyme Activation; Female; Gene Expression Regulation; Genetic Therapy; Indoles; Male; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Infarction; Myocardium; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction	2006
VCAM-1 signals activate endothelial cell protein kinase Calpha via oxidation. Journal of immunology (Baltimore, Md. : 1950), 2006, Nov-01, Volume: 177, Issue:9 Topics: Animals; Antibodies; Carbazoles; Cell Movement; Cells, Cultured; Endothelial Cells; Enzyme Activation; Humans; Hydrogen Peroxide; Indoles; Mice; NADPH Oxidases; Oxidation-Reduction; Phosphorylation; Protein Kinase C-alpha; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Spleen; Threonine; Vascular Cell Adhesion Molecule-1	2006
Protein kinase C inhibition attenuates vascular ETB receptor upregulation and decreases brain damage after cerebral ischemia in rat. BMC neuroscience, 2007, Jan-09, Volume: 8 Topics: Animals; Atrophy; Brain; Brain Ischemia; Cerebrovascular Circulation; Indoles; Male; Middle Cerebral Artery; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Receptor, Endothelin B; Up-Regulation	2007
Trace amine-associated receptor 1 is a modulator of the dopamine transporter. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1 Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Luciferases; Macaca mulatta; Methamphetamine; Methylphenidate; Phosphorylation; Protein Kinase C; Pyrroles; Receptors, G-Protein-Coupled; Stimulation, Chemical	2007
Negative regulation of cyclin-dependent kinase 5 targets by protein kinase C. European journal of pharmacology, 2008, Mar-10, Volume: 581, Issue:3 Topics: Animals; Cyclin-Dependent Kinase 5; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Response Relationship, Drug; Immunoprecipitation; In Vitro Techniques; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Proteins; Pyrroles; Time Factors	2008
Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism. American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:4 Topics: Bacterial Proteins; beta Catenin; Butadienes; Caco-2 Cells; Cadherins; Dose-Response Relationship, Drug; Electric Impedance; HT29 Cells; Humans; Hydrogen Peroxide; Indoles; Intestinal Mucosa; Inulin; Lacticaseibacillus rhamnosus; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Occludin; Permeability; Phosphoproteins; Probiotics; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Pyrroles; Tight Junctions; Time Factors; Zonula Occludens-1 Protein	2008
Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release. Journal of biomedical science, 2009, Aug-11, Volume: 16 Topics: Animals; Apoptosis; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Cytochromes c; Indoles; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Donors; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Triazenes	2009
Mechanism for carbachol-induced secretion of lacritin in cultured monkey lacrimal acinar cells. Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:9 Topics: Anilides; Animals; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Enzyme Inhibitors; Eye Proteins; Gene Expression Profiling; Glycoproteins; Immunohistochemistry; Indoles; Lacrimal Apparatus; Macaca mulatta; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; Protein Kinase C; Pyrroles; RNA, Messenger; Signal Transduction; Thiadiazoles	2010
Glycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradation. Oncogene, 2011, May-26, Volume: 30, Issue:21 Topics: Carbazoles; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoblotting; Immunoprecipitation; Indoles; Jurkat Cells; Maleimides; Mutation; Phosphorylation; Protein Binding; Protein Kinase C; Pyrroles; RNA Interference; Signal Transduction; Substrate Specificity; Transcription Factor RelB	2011
Intermittent administration of PTH(1-34) regulates the osteoblastic differentiation of human periodontal ligament cells via protein kinase C- and protein kinase A-dependent pathways in vitro. Journal of periodontal research, 2011, Volume: 46, Issue:3 Topics: Adolescent; Alkaline Phosphatase; Calcification, Physiologic; Cell Count; Cell Culture Techniques; Cell Differentiation; Cell Physiological Phenomena; Child; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Extracellular Matrix; Humans; Indoles; Isoquinolines; Osteoblasts; Osteocalcin; Parathyroid Hormone; Peptide Fragments; Periodontal Ligament; Protein Kinase C; Pyrroles; Signal Transduction; Teriparatide	2011
VEGFR1 and PKCα signaling control melanoma vasculogenic mimicry in a VEGFR2 kinase-independent manner. Melanoma research, 2011, Volume: 21, Issue:2 Topics: Animals; Cell Line, Tumor; Female; Humans; Indoles; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Protein Kinase C-alpha; Pyrroles; RNA, Small Interfering; Signal Transduction; Skin Neoplasms; Transfection; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2	2011
Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability. American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:6 Topics: 2-Methoxyestradiol; Animals; Capillary Permeability; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Estradiol; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Indoles; Male; Maleimides; Membrane Proteins; Mice; Microfilament Proteins; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Protein Kinase C; Pyrroles; rho-Associated Kinases; Tubulin Modulators	2011
Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury. Circulation research, 2011, Dec-09, Volume: 109, Issue:12 Topics: Animals; Cardiac Output; Coronary Occlusion; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heart; Heart Failure; Indoles; Maleimides; Myocardial Contraction; Myocardial Infarction; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Stroke Volume; Swine	2011
Intermittent PTH(1-34) signals through protein kinase A to regulate osteoprotegerin production in human periodontal ligament cells in vitro. Clinical oral investigations, 2012, Volume: 16, Issue:2 Topics: Adolescent; Cell Culture Techniques; Child; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Isoquinolines; Osteoprotegerin; Parathyroid Hormone; Peptide Fragments; Periodontal Ligament; Protein Kinase C; Pyrroles; Signal Transduction; Teriparatide	2012
C1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosis. Cancer biology & therapy, 2012, Volume: 13, Issue:10 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Indoles; Injections, Intralesional; Isoenzymes; Mice; Mice, SCID; Peptide Fragments; Peptides; Phosphorylation; Protein Interaction Domains and Motifs; Protein Kinase C; Pyrroles; Serine; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2012
Ro 32-0432 attenuates mecamylamine-precipitated nicotine withdrawal syndrome in mice. Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:3 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 5; Indoles; Male; Maze Learning; Mecamylamine; Mice; Nicotine; Pyrroles; Substance Withdrawal Syndrome	2013
Potential involvement of μ-opioid receptor dysregulation on the reduced antinociception of morphine in the inflammatory pain state in mice. Journal of pharmacological sciences, 2014, Volume: 124, Issue:2 Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Indoles; Inflammation; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Phosphorylation; Protein Kinase C-alpha; Pyrroles; Receptors, Opioid, mu; Spinal Cord	2014
Translocation of protein kinase C δ contributes to the moderately high glucose-, but not hypoxia-induced proliferation in primary cultured human retinal endothelial cells. Molecular medicine reports, 2014, Volume: 9, Issue:5 Topics: Acetophenones; Benzopyrans; Cell Proliferation; Cells, Cultured; Endothelial Cells; Gene Expression; Glucose; Humans; Hypoxia; Indoles; Primary Cell Culture; Protein Kinase C-delta; Protein Transport; Pyrroles; Retinal Pigment Epithelium	2014
PKC activators enhance GABAergic neurotransmission and paired-pulse facilitation in hippocampal CA1 pyramidal neurons. Neuroscience, 2014, May-30, Volume: 268 Topics: Action Potentials; Animals; Bryostatins; CA1 Region, Hippocampal; Caprylates; Enkephalin, Methionine; Enzyme Activators; Enzyme Inhibitors; gamma-Aminobutyric Acid; Indoles; Inhibitory Postsynaptic Potentials; Interneurons; Male; Maze Learning; Neurotransmitter Agents; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Pyramidal Cells; Pyrroles; Rats; Synapses; Synaptic Transmission	2014
Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-κB pathways in human lung epithelial cells. European journal of pharmacology, 2015, Nov-15, Volume: 767 Topics: Animals; Apigenin; Casein Kinase II; Cells, Cultured; Epithelial Cells; Humans; Indoles; Interleukin-8; Lung; NF-kappa B; Phosphorylation; Pyrroles; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Thrombin; Transcription Factor RelA; Triazoles	2015
PKC-dependent phosphorylation of Munc18a at Ser313 in activated RBL-2H3 cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2018, Volume: 67, Issue:1 Topics: Animals; Cell Degranulation; Cell Line, Tumor; Indoles; Mast Cells; Munc18 Proteins; Phosphorylation; Protein Kinase C; Pyrroles; Rats	2018