Compounds > ro 32-0432
Page last updated: 2024-09-03

ro 32-0432 and bisindolylmaleimide i

ro 32-0432 has been researched along with bisindolylmaleimide i in 4 studies

Compound Research Comparison

Studies
(ro 32-0432)		Trials
(ro 32-0432)		Recent Studies (post-2010)
(ro 32-0432)		Studies
(bisindolylmaleimide i)		Trials
(bisindolylmaleimide i)		Recent Studies (post-2010) (bisindolylmaleimide i)
560131,1981174

Protein Interaction Comparison

ProteinTaxonomyro 32-0432 (IC50)bisindolylmaleimide i (IC50)
Chain A, Protein kinase C, iotaHomo sapiens (human)5.8
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)9
G2/mitotic-specific cyclin-B2Homo sapiens (human)2.3
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.5
Protein kinase C gamma typeHomo sapiens (human)0.03
Protein kinase C beta typeHomo sapiens (human)0.0054
Cyclin-dependent kinase 1Homo sapiens (human)2.3
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.068
Cyclin-dependent kinase 4Homo sapiens (human)0.99
G2/mitotic-specific cyclin-B1Homo sapiens (human)2.3
Lethal factorBacillus anthracis1.5
Protein kinase C alpha typeHomo sapiens (human)0.0055
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.36
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoformOryctolagus cuniculus (rabbit)0.7
G1/S-specific cyclin-D1Homo sapiens (human)0.99
Protein kinase C eta typeHomo sapiens (human)0.0066
G1/S-specific cyclin-E1Homo sapiens (human)0.99
Cyclin-dependent kinase 2Homo sapiens (human)0.99
cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus (Norway rat)2
Protein kinase C iota typeHomo sapiens (human)3.463
Glycogen synthase kinase-3 betaHomo sapiens (human)0.19
Protein kinase C epsilon typeHomo sapiens (human)0.0067
Protein kinase C theta typeHomo sapiens (human)0.0061
Protein kinase C zeta typeHomo sapiens (human)5.8
Protein kinase C delta typeHomo sapiens (human)0.0096
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)0.006
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)7.3
G2/mitotic-specific cyclin-B3Homo sapiens (human)2.3
Serine/threonine-protein kinase LMTK3Homo sapiens (human)0.0001

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goekjian, PG; Jirousek, MR1
Han, JS; Kim, DS; Kim, TW; Yoon, MS1
Bowman, L; Castranova, V; Ding, M; Huang, C; Lu, Y; Vallyathan, V1
Azuma, M; Morimoto-Tochigi, A; Nakajima, E; Shearer, TR; Walkup, RD1

Reviews

1 review(s) available for ro 32-0432 and bisindolylmaleimide i

ArticleYear
Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.
    Current medicinal chemistry, 1999, Volume: 6, Issue:9

    Topics: Azepines; Bryostatins; Carbazoles; Enzyme Inhibitors; Humans; Hydroxybenzoates; Indoles; Lactones; Macrolides; Maleimides; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Pyrroles; Signal Transduction; Thionucleotides

1999

Other Studies

3 other study(ies) available for ro 32-0432 and bisindolylmaleimide i

ArticleYear
Thyrotropin-releasing hormone increases phospholipase D activity through stimulation of protein kinase C in GH3 cells.
    Endocrine, 2004, Volume: 23, Issue:1

    Topics: Animals; Calcium; Cell Line, Tumor; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Isoenzymes; Maleimides; Phospholipase D; Protein Kinase C; Protein Transport; Pyrroles; Pyrrolidinones; Rats; Thyrotropin-Releasing Hormone

2004
Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2

    Topics: Animals; Cell Line; Crystallization; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; MAP Kinase Signaling System; Mice; Naphthalenes; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Pyrroles; Silicon Dioxide; Transcription Factor AP-1; Transfection

2006
Mechanism for carbachol-induced secretion of lacritin in cultured monkey lacrimal acinar cells.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:9

    Topics: Anilides; Animals; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Enzyme Inhibitors; Eye Proteins; Gene Expression Profiling; Glycoproteins; Immunohistochemistry; Indoles; Lacrimal Apparatus; Macaca mulatta; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; Protein Kinase C; Pyrroles; RNA, Messenger; Signal Transduction; Thiadiazoles

2010