Compounds > ro 32-0432
Page last updated: 2024-09-03

ro 32-0432 and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ro 32-0432 has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 2 studies

Compound Research Comparison

Studies
(ro 32-0432)		Trials
(ro 32-0432)		Recent Studies (post-2010)
(ro 32-0432)		Studies
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)		Trials
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)		Recent Studies (post-2010) (2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)
560134,82351,810

Protein Interaction Comparison

ProteinTaxonomyro 32-0432 (IC50)2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one (IC50)
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Methyltransferase WbddEscherichia coli68
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)1.6413
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)1.4218
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.002
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)9.614
Cytochrome P450 1A2Homo sapiens (human)1
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)1.6
Serine/threonine-protein kinase pim-1Homo sapiens (human)3.364
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)1.6
Casein kinase II subunit alpha'Homo sapiens (human)6.9
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)3.1638
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.796
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.002
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)2.3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformBos taurus (cattle)3.7533
Type-1 angiotensin II receptorOryctolagus cuniculus (rabbit)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)1.4593
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Mus musculus (house mouse)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)1.2922
Serine/threonine-protein kinase mTORHomo sapiens (human)4.1638
Serine/threonine-protein kinase mTORRattus norvegicus (Norway rat)2.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)2.4845
Glycogen synthase kinase-3 betaHomo sapiens (human)8.1
Serine/threonine-protein kinase PLK1Homo sapiens (human)2.05
Casein kinase II subunit betaHomo sapiens (human)6.9
Casein kinase II subunit alphaHomo sapiens (human)6.9
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)1.32
Mu-type opioid receptorCavia porcellus (domestic guinea pig)1.6
Serine/threonine-protein kinase pim-3Homo sapiens (human)1.4
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)1.72
Serine/threonine-protein kinase PLK3Homo sapiens (human)3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akao, Y; Iinuma, M; Itoh, T; Nozawa, Y; Ohguchi, K1
Brown, Z; Cronshaw, DG; Kouroumalis, A; Parry, R; Ward, SG; Webb, A1

Other Studies

2 other study(ies) available for ro 32-0432 and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation.
    Bioorganic & medicinal chemistry, 2008, Apr-15, Volume: 16, Issue:8

    Topics: Animals; Calcium; Cell Degranulation; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Garcinia mangostana; Histamine; Immunoglobulin E; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; MAP Kinase Signaling System; Molecular Structure; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Protein-Tyrosine Kinases; Rats; Reactive Oxygen Species; Receptors, IgE; Structure-Activity Relationship; Syk Kinase; Xanthones

2008
Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22.
    Journal of leukocyte biology, 2006, Volume: 79, Issue:6

    Topics: Acetophenones; Benzopyrans; Calcium; Calcium Channels; Calcium Signaling; Catalytic Domain; Cell Line, Tumor; Chemokine CCL17; Chemokine CCL22; Chemokines, CC; Chemotaxis; Chromones; Diglycerides; Estrenes; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Leukemia-Lymphoma, Adult T-Cell; Morpholines; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphothreonine; Protein Processing, Post-Translational; Pyrroles; Pyrrolidinones; Receptors, CCR4; Receptors, Chemokine; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; T-Lymphocytes; Th2 Cells

2006